Does leukocytospermia associate with poor semen parameters and sperm functions in male infertility?The role of different seminal leukocyte concentrations

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 89, Issue 2, 2000, Pages 185-191

  Kaleli, Semih ^a   Öçer, Fahri ^a   Irez, Tülay ^a   Budak, Erdal ^a   Aksu, M Feridun ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Acrosome reaction; Antisperm antibody; Hypoosmotic swelling test; Leukocytospermia; Semen analysis

Indexed keywords

SPERM ANTIBODY;

ACROSOME REACTION; ADULT; ARTICLE; CLINICAL TRIAL; HUMAN; HUMAN CELL; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OSMOTIC STRESS; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERM; UTERINE CERVIX MUCUS; WORLD HEALTH ORGANIZATION;

EID: 0034175752     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-2115(99)00204-3     Document Type: Article

References (39)

1. Hill J.A., Cohen J., Anderson D.J. The effects of lymphokines and monokines on human sperm fertilizing ability in the zona-free hamster egg penetration test. Am J Obstet Gynecol. 160:1989;1154-1159.
2. Barratt C.L.R., Bolton A.E., Cooke I.D. Functional significance of white blood cells in the male and female reproductive tract. Hum Reprod. 5:1990;639-648.
3. Krausz C., Mills C., Rogers S., Tan S.L., Aitken R.J. Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: relationships with motility and fertilization in vitro. Fertil Steril. 62:1994;599-605.
4. Wolff H., Politch J.A., Martinez A., Haimovici F., Hill J.A., Anderson D.J. Leukocytospermia is associated with poor semen quality. Fertil Steril. 53:1990;528-536.
5. Hill J.A., Haimovici F., Politch J.A., Anderson D.J. Effects of soluble products of activated lymphocytes and macrophages (lymphokines and monokines) on human sperm motion parameters. Fertil Steril. 47:1987;460-465.
6. Chan P.J., Su B.C., Tredway D.R., Whitney E.A., Pang S.C., Corselli J., Jacobsen J.D. White blood cells in semen affect hyperactivation but not sperm membrane integrity in the head and tail regions. Fertil Steril. 61:1994;986-989.
7. de Lamirande E., Gagnon C. Reactive oxygen species and human spermatozoa. I. Effects on the motility of intact spermatozoa and on sperm axonemes. J Androl. 13:1992;368-378.
8. Tomlinson M.J., Barratt C.L.R., Cooke I.D. Prospective study of leukocytes and leukocytes subpopulations in semen suggests that they are not a cause of male infertility. Fertil Steril. 60:1993;1069-1075.
9. El-Demiry M.I.M., Young H., Elton R., Hargreave T.B., James K., Chisholm G.D. Leukocytes in the ejaculates from fertile and infertile men. Br J Urol. 58:1986;715-720.
10. Glezermen M., Lunenfeld B. Diagnosis of male infertility. Insler V., Lunenfeld B., Infertility: Male and Female. 1993;317-332 Churchill Livingstone, London.
11. WHO Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 3rd edn :1992;8-50 The Press Syndicate of the University of Cambridge, London.
12. Garde J.J., Ortiz N., Garcia A., Gallego L. Use of triple-stain technique to detect viability and acrosome reaction in deer spermatozoa. Arch Androl. 39:1997;1-9.
13. Metzel S. Molecules that initiate or help stimulate the acrosome reaction by their interaction with mammalian sperm surface. Am J Anat. 174:1985;285-291.
14. Aitken R.J., Clarkson J.S. Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa. J Reprod Fertil. 81:1987;459-469.
15. Ichikawa T., Oeda T.I., Ohmori H.I., Schill W.-B.I. Reactive oxygen species influence the acrosome reaction but not acrosin activity in human spermatozoa. Int J Androl. 22:1999;37-42.
16. Bize I., Santander G., Cabello P., Driscoll D., Sharpe C. Hydrogen peroxides involved in hamster sperm capacitation in vitro. Biol Reprod. 44:1991;398-403.
17. Griveau J.F., Renard P., Le Lannou D. Superoxide anion production by human spermatozoa as a part of the ionophore-induced acrosome reaction process. Int J Androl. 18:1995;67-74.
18. de Lamirande E., Conyee T., Azia H., Gagnon C. Involvement of reactive oxygen species in human sperm acrosome reaction induced by A23187, lysophosphatidylcholine, and biological fluids. Fertil Steril. 70:(2S):1998;463. (abstract).
19. Dimitrov D.G., Petrovska M. Effects of products of activated immune cells and recombinant cytokines on spontaneous and ionophore-induced acrosome reaction. Am J Reprod Immunol. 36:1996;150-156.
20. Naz R.K., Kaplan P. Interleukin-6 enhances the fertilizing capacity of human sperm by increasing capacitation and acrosome reaction. J Androl. 15:(3):1994;228-233.
21. Gavella M., Lipovac V. Effect of leukocytes on the hypoosmotic swelling test of human sperm. Arch Androl. 30:1993;55-61.
22. Estrada L.S., Champion H.C., Wang R., Rajasekaran M., Hellstrom W.J., Aggarwal B., Sikka S.C. Effect of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human sperm motility, viability and motion parameters. Int J Androl. 20:1997;237-242.
23. de Lamirande E., Gagnon C. Reactive oxygen species and human spermatozoa. I. Effects on the motility of intact spermatozoa and on sperm axonemes. J Androl. 13:1992;368-378.
24. Arienti G., Carlini E., Saccardi C., Palmerini C.A. Interactions between prostasomes and leukocytes. Biochim Biophys Acta. 1425:(1):1998;36-40.
25. Carlini E., Palmerini C.A., Cosmi E.V., Arienti G. Fusion of sperm with prostasomes: effects on membrane fluidity. Arch Biochem Biophys. 343:1997;6-12.
26. Haidl G., Schill W.B. Changes of sperm tail morphology after kallikrein treatment. Arch Androl. 31:1993;1-8.
27. Wolff H., Anderson D.J. Immunohistologic characterization and quantitation of leukocyte subpopulations in human semen. Fertil Steril. 49:1988;497-504.
28. Ritchie A.W.S., Hargeave T.B., James K., Chisholm G.D. Intraepithelial lymphocytes in the normal epididymis: a mechanism for tolerance to sperm auto-antigens? Br J Urol. 56:1984;79-84.
29. Hsu S., Jaffe E.S. Leu M1 and peanut agglutinin stain the neoplastic cells of Hodgkin disease. Am J Clin Pathol. 82:1984;29-33.
30. Witkin S.S. Enzyme-linked immunosorbent assays for detection of antibodies to spermatozoa. Res Reprod. 15:1983;1-9.
31. Baker H.W.G., Brindle J., Irvine D.S., Aitken R.J. Protective effect of antioxidants on the impairment of sperm motility by activated polymorphonuclear leukocytes. Fertil Steril. 65:1996;411-419.
32. Plante M., de Lamirande E., Gagnon C. Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility. Fertil Steril. 62:1994;387-393.
33. Glezerman M., Bartoov B. Semen analysis. Insler V., Lunenfeld B., Infertility: Male and Female. 1993;285-316 Churchill Livingstone, London.
34. Fair W.R., Clark R.B., Webner N. A correlation of seminal polyamine levels and semen analysis in the human. Fertil Steril. 23:1972;38-42.
35. Parrish R.F., Goodpasture J.C., Zaneveld L.J.D., Polakoski K.L. Polyamine inhibition of the conversion of human proacrosin to acrosin. J Reprod Fertil. 57:1979;239-243.
36. Anderson D.J. Should male infertility patients be tested for leukocytospermia? Fertil Steril. 63:1995;246-248.
37. Kiessling A.A., Lamparelli N., Yin H.Z., Seibel M.M., Eyre R.C. Semen leukocytes: friends or foes? Fertil Steril. 64:1995;196-198.
38. Depuydt C., Zalata A., Christophe A., Mahmoud A., Comhaire F. Mechanisms of sperm deficiency in male accesory gland infection. Andrologia. 30:(Suppl. 1):1998;29-33.
39. Keck C., Gerber-Schafer C., Clad A., Wilhelm C., Breckwoldt M. Seminal tract infections. Impact on male fertility and treatment options. Hum Reprod Update. 4:(6):1998;891-903.