Ionic transport in tall columnar epithelial (TCE) cells obtained by nasal brushing from non-cystic fibrosis (CF) individuals

Acta Medica Portuguesa

Volumn 17, Issue 6, 2004, Pages 427-434

  Mauricio, Ana C ^a   Penque, D ^a   Amaral, M D ^a   Ferreira, K T G ^a  

^a NONE

Author keywords

CFTR; Chloride; Functional assessment; Nasal brushing; ORCC; Patch clamp; Tall columnar epithelial (TCE) cells

Indexed keywords

CHLORIDE CHANNEL; CYCLIC AMP; ISOBUTYLMETHYLXANTHINE;

AIRWAY; ARTICLE; CELL FUNCTION; CELL ISOLATION; CHLORIDE CONDUCTANCE; COLUMNAR EPITHELIUM; CYSTIC FIBROSIS; ELECTRIC POTENTIAL; FACIAL BONE; FUNCTIONAL ASSESSMENT; HUMAN; HUMAN CELL; ION TRANSPORT; LOWER RESPIRATORY TRACT; NORMAL HUMAN; NOSE MUCOSA; PATCH CLAMP;

BIOLOGICAL TRANSPORT; CELLS, CULTURED; ELECTROPHYSIOLOGY; EPITHELIAL CELLS; HUMANS; IONS; NOSE;

EID: 14844303736     PISSN: None     EISSN: 16460758     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. - conductance through CFTR in human airway epithelia. Am J Physiol 1997; 272 (4 Pt 1), L752-L761.
2. HUG MJ, TAMADA T, BRIDGES RJ: CFTR and bicarbonate secretion by epithelial cells. News Physiol Sci 2003; 18: 32-42.
3. STUTTS MJ, CANESSA CM, OLSEN JC, HAMRICK M, COHN JA, ROSSIER BC, BOUCHER RC: CFTR as a cAMP-dependent regulator of sodium channels. Science 1995; 269: 847-850.
4. - channels by protein kinase A corrected by insertion of CFTR. Nature 1992; 358: 581-584.
5. HRYCIN DH, GUGGINO WB: Cystic fibrosis transmembrane conductance regulator and the outwardly rectifying chloride channel: a relationship between two chloride channels expressed in epithelial cells. Clin Exp Pharmacol Physiol 2000; 27: 892-895.
6. BRADBURY NA, JILLING T, BERTA G, SORSCHER EJ, BRIDGES RJ, KIRK KL: Regulation of plasma membrane recycling by CFTR. Science 1992; 256: 530-532.
7. PRINCE LS, WORKMAN RBJ, MARCHASE RB: Rapid endocytosis of the cystic fibrosis transmembrane conductance regulator chloride channel. Proc Natl Acad Sci U.S.A. 1994; 91: 5192-5196.
8. BIWERSI J, EMANS N, VERKMAN AS: Cystic fibrosis transmembrane conductance regulator activation stimulates endosome fusion in vivo. Proc Natl Acad Sci U.S.A. 1996; 93: 12484-12489.
9. TAKAHASHI A, WATKINS SC, HOWARD M, FRIZZELL RA: CFTR - dependent membrane insertion is linked to stimulation of the CFTR chloride conductance. Am J Physiol 1996; 271: C1887-C1894.
10. 2+ or microfilaments. J Cell Sci 1996; 109: 1325-1334.
11. WEBER WM, CUPPENS H, CASIMAN JJ, CLAUSS W, VAN DRIESSCHE W: Capacitance measurements reveal different pathways for the activation of CFTR. Pflügers Arch 1999; 438: 561-569.
12. --secreting epithelial cells. Pro. Natl Acad Sci U.S.A. 1990; 87: 4956-4960.
13. - secretion in epithelial cells. Am J Physiol 1994; 266: 254-268.
14. KNOWLES M, GATZY J, BOUCHER R: Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis. N Engl J Med 1981; 305: 1489-1495.
15. HAY JG, GEDDES DM: Transepithelial potential difference in cystic fibrosis. Thorax 1985; 40: 493-496.
16. ALTON EW, HAY JG, MUNRO C, GEDDES DM: Measurement of nasal potential difference in adult cystic fibrosis, Young's syndrome, and bronchiectasis. Thorax 1987; 42: 815-817.
17. HOFFMANN T, BOHMER O, HULS G, TERBRACK HG, BITTNER P, KLINGMULLER V, HEERD E, LINDEMANN H: Conventional and modified nasal potential-difference measurement in cystic fibrosis. Am J Respir Crit Care Med 1997; 155: 1908-1913.
18. HO LP, SAMWAYS JM, PORTEOUS DJ, DORIN JR, CAROTHERS A, GREENING AP, INNES JA: Correlation between nasal potential difference measurements, genotype and clinical condition in patients with cystic fibrosis. Eur Respir Jour 1997; 10(9): 2018-2022.
19. JACQUOT J, PUCHELLE E, HINNRASKY J, FUCHEY C, BETTINGER C, SPILMONT C, BONNET N, DIETERLE A, DREYER D, PAVIRANI A: Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands. Eur. Respir. J. 1993; 6: 169-176.
20. BRÉZILLON S, DUPUIT F, HINNRASKY J, MARCH V, KÄLIN N, TÜMMLER B, PUCHELLE E: Decreased expression of the CFTR protein in remodeled human nasal epithelium from non-cystic fibrosis patients. Lab Invest 1995; 72: 191-200.
21. BECK S, PENQUE D, GARCIA S, GOMES A, FARINHA C, MATA L, GULBENKIAN S, GIL-FERREIRA K, DUARTE A, PACHECO P, BARRETO C, LOPES B, CAVACO J, LAVINHA J, AMARAL MD: Cystic fibrosis patients with the 3272-26A>G mutation have mild disease, leaky alternative mRNA splicing, and CFTR protein at the cell membrane. Hum Mutat 1999; 14: 133-144.
22. RAMALHO AS, BECK S, MEYER M, PENQUE D, CUTTING GR, AMARAL MD: Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis. Am J Resp Cell Mol Biol 2002; 27(5): 619-627.
23. PENQUE D, MENDES F, BECK S, FARINHA C, PACHECO P, NOGUEIRA P, LAVINHA L, MALH R, AMARAL MD: Cystic fibrosis F508del patients have apically localized CFTR in a reduced number airway cells. Lab Invest 2000; 80: 857-868.
24. CARVALHO-OLIVEIRA I, EFTHYMIADOU A, TZETIS M, KANAVAKIS E, MALHO R, AMARAL MD, PENQUE D: Localization of CFTR in airway cells of Cystic Fibrosis patients and controls and cell lines expressing wil-type or F508del-CFTR by a panel of different antibodies. J Histochem Cytochem 2004; 52(2), 193-203.
25. DUARTE A, AMARAL M, BARRETO C, PACHECO P, LAVINHA J: Complex cystic fibrosis allele R334W-R1158X results in reduced levels of correctly processed mRNA in a pancreatic sufficient patient. Human Mutat 1996; 8: 134-139.
26. DACIE JV, LEWIS SM: Practical Haematology. Edinburgh. Churchill Livingston 1985.
27. DANEL C, ERZURUM SC, MCELVANEY NG, CRYSTAL RG: Quantitative assessment of the epithelial and inflammatory cell populations in large airways of normal and individuals with cystic fibrosis. Am J Respir Crit Care Med 1996; 153: 362-368.
28. GREGORY RJ, CHENG SH, RICH DP, MARSHALL J, PAUL S, HEHIR K, OSTEDGAARD L, KLINGER KW, WELSH MJ, SMITH AE: Expression and characterization of the cystic fibrosis transmembrane conductance regulator. Nature 1990; 347: 382-386.
29. HAMILL OP, MARTY A, NEHER E, SACKMANN B, SIGWORTH FJ: Improved patch - clamp techniques for high-resolution current recording from cells and cell - free membrane patches. Pflügers Arch 1981; 391: 85-100.
30. HALD A: Statistical Theory with Engineering Applications, pp. 391-394. John Wiley, New York, 1952.
31. FERREIRA KTG, FERNANDES PL, FERREIRA HG: Ion transport across the epithelium of the rabbit caecum. Biochimica et Biophysica Acta 1992; 1175: 27-36.
32. GRYGORCZYK R, BRIDGES MA: Whole-cell chloride conductances in cultured brushed human nasal epithelial cells. Can J Physiol Pharmacol 1992; 70(8): 1134-1141.
33. MCCANN JD, LI M, WELSH MJ: Identification and regulation of whole-cell chloride currents in airway epithelium. J Gen Physiol 1989; 94(6): 1015-1036.
34. + conductance in cystic fibrosis. Pflügers Arch 1995; 431: 1-9.
35. SCHWIEBERT EM, FLOTTE T, CUTTING GR, GUGGINO WB: Both CFTR and outwardly rectifying chloride channels contribute to cAMP-stimulated whole cell chloride currents. Am J Physiol 1994; 266: C1464-1477.