DNA motif associated with meiotic double-strand break regions in Saccharomyces cerevisiae

EMBO Reports

Volumn 1, Issue 3, 2000, Pages 232-238

  Blumental Perry, A ^a   Zenvirth, D ^a   Klein, S ^a   Onn, I ^a   Simchen, G ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ARG4 PROTEIN, S CEREVISIAE; FUNGAL DNA; FUNGAL PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CHEMISTRY; CHROMATIN; CHROMOSOME; CHROMOSOME BREAKAGE; CONFORMATION; FUNGAL GENE; GENETIC RECOMBINATION; GENETICS; MEIOSIS; METABOLISM; NUCLEOTIDE SEQUENCE; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

BASE SEQUENCE; CHROMATIN; CHROMOSOME BREAKAGE; CHROMOSOMES, FUNGAL; DNA, FUNGAL; FUNGAL PROTEINS; GENES, FUNGAL; MEIOSIS; NUCLEIC ACID CONFORMATION; PROMOTER REGIONS (GENETICS); RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0034280799     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvd047     Document Type: Article

References (23)

1. Alani, E., Padmore, R. and Kleckner, N. (1990) Analysis of wild type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell, 61, 419-436.
2. Baudat, F. and Nicolas, A. (1997) Clustering of meiotic double-strand breaks on yeast chromosome III. Proc. Natl Acad. Sci. USA, 94, 5213-5218.
3. Bergerat, A., de Massy, B., Gadelle, D., Varoutas, P.C., Nicolas, A. and Forterre, P. (1997) An atypical topoisomerase II from archaea with implication for meiotic recombination. Nature, 386, 414-417.
4. Borde, V., Wu, T.C. and Lichten, M. (1999) Use of a recombination reporter insert to define meiotic recombination domains on chromosome III of S. cerevisiae. Mol. Cell. Biol., 19, 4832-4842.
5. de Massy, B. and Nicolas, A. (1993) The control in cis of the position and the amount of the ARG4 meiotic double-strand break of 5. cerevisiae. EMBO J., 12, 1459-1466.
6. de Massy, B., Rocco, V. and Nicolas, A. (1995) The nucleotide mapping of DNA double-strand breaks at the CYS3 initiation site of meiotic recombination in S. cerevisiae. EMBO J., 14, 4589-1598.
7. Fan, Q., Xu, F. and Petes, T.D. (1995) Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast S. cerevisiae: control in cis and trans. Mol. Cell. Biol., 15, 1679-1688.
8. Goldway, M., Sherman, A., Zenvirth, D., Arbel, T. and Simchen, G. (1993) A short chromosomal region with major roles in yeast chromosome III meiotic disjunction, recombination and double strand breaks. Genetics, 133, 159-169.
9. Grunstein, M. (1997) Molecular model for telomeric heterochromatin in yeast. Curr. Opin. Cell Biol., 9, 383-387.
10. Guarente, L. (1999) Diverse and dynamic functions of the Sir silencing complex. Nature Genet., 23, 281-285.
11. Keeney, S., Giroux, C.N. and Kleckner, N. (1997) Meiosis-specific DNA double-strand breaks are catalyzed by Spoil, a member of a widely conserved protein family. Cell, 88, 375-384.
12. Klein, S., Zenvirth, D., Dror, V., Barton, A.B., Kaback, D.B. and Simchen, G. (1996) Patterns of meiotic double-strand breakage on native and artificial yeast chromosomes. Chromosoma, 105, 276-284.
13. Liu, J., Wu, T.C. and Lichten, M. (1995) The location and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate. EMBO J., 14, 4599-4608.
14. Ohta, K., Shibata, T. and Nicolas, A. (1994) Changes in chromatin structure at recombination initiation sites during yeast meiosis. EMBO J., 13, 5754-5763.
15. Ohta, K., Nicolas, A., Furuse, M., Nabetani, A., Ogawa, H. and Shibata, T. (1998) Mutations in the MRE11, RAD50, XRS2, and MKE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc. Natl Acad. Sci. USA, 95, 646-651.
16. Smith, K.N. and Nicolas, A. (1998) Recombination at work for meiosis. Curr. Opin. Genet. Dev., 8, 200-211.
17. Wang, J.C. (1996) DNA topoisomerases. Annu. Rev. Biociiem., 65, 635-692.
18. Wu, T.C. and Lichten, M. (1994) Meiosis-induced double-strand break sites determined by yeast chromatin structure. Science, 263, 515-518.
19. Wu, T.C. and Lichten, M. (1995) Factors that affect the location and frequency of meiosis-induced double-strand breaks in S. cerevisiae. Genetics, 140, 55-66.
20. Wyrick, J.J., Holstege, F.C., Jennings, E.G., Causton, H.C., Shore, D., Grunstein, M., Lander, E.S. and Young, R.A. (1999) Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast. Nature, 402, 418-121.
21. Xu, F. and Petes, T.D. (1996) Fine-structure mapping of meiosis-specific double-strand DNA breaks at a recombination hotspot associated with an insertion of telomeric sequences upstream of the HIS4 locus in yeast. Genetics, 143, 1115-1125.
22. Xu, L. and Kleckner, N. (1995) Sequence non-specific double-strand breaks and interhomolog interactions prior to double-strand break formation at a meiotic recombination hot spot in yeast. EMBO J., 14, 5115-5128.
23. Zenvirth, D., Arbel, T., Sherman, A., Goldway, M., Klein, S. and Simchen, G. (1992) Multiple sites for double-strand breaks in whole meiotic chromosomes of 5. cerevisiae. EMBO J., 11, 3441-3447.