Semiautomated cell-free conversion of prion protein: Applications for high-throughput screening of potential antiprion drugs

Analytical Biochemistry

Volumn 339, Issue 1, 2005, Pages 165-173

  Breydo, Leonid ^a   Bocharova, Olga V ^a   Baskakov, Ilia V ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloid fibrils; Cell free conversion; High throughput assay; Prion protein; Thioflavin T

Indexed keywords

DIAGNOSIS; GLYCOPROTEINS; MAMMALS; RECOMBINANT PROTEINS;

AMYLOID FIBRIL; CELL-FREE; HIGH-THROUGHPUT ASSAYS; PRION PROTEIN; THIOFLAVIN T;

PRASEODYMIUM COMPOUNDS;

BLOCKING AGENT; CONGO RED; CURCUMIN; DENDRIMER; MEPACRINE; PAMAM DENDRIMER; PHTHALOCYANINE TETRASULFONATE NICKEL; PRION PROTEIN; RECOMBINANT PROTEIN; TETRACYCLINE; TETRAKIS(4 N METHYLPYRIDINE)PORPHINE IRON; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BIOASSAY; CELL FREE SYSTEM; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 14844286460     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2005.01.003     Document Type: Article

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