The role of alternative splicing and C-terminal amino acids in thromboxane receptor stabilization

Biochemical and Biophysical Research Communications

Volumn 329, Issue 3, 2005, Pages 898-904

  Valentin, François ^a   Tippins, John R ^a   Field, Mark C ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

ER associated degradation; Isoprostane; Mutagenesis; Oxidative stress; Protein turnover; Thromboxane

Indexed keywords

AMINO ACID; ARGININE; ISOPROTEIN; THROMBOXANE RECEPTOR;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLUSTER ANALYSIS; CONTROLLED STUDY; NONHUMAN; NONSENSE MUTATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS;

EID: 14844283128     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.02.058     Document Type: Article

References (28)

1. S. Narumiya, Y. Sugimoto, and F. Ushikubi Prostanoid receptors: structures, properties, and functions Physiol. Rev. 79 1999 1193 1226
2. M. Negishi, Y. Sugimoto, and A. Ichikawa Prostanoid receptors and their biological actions Prog. Lipid Res. 32 1993 417 434
3. R.A. Coleman, W.L. Smith, and S. Narumiya International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes Pharmacol. Rev. 46 1994 205 229
4. M. Hirata, Y. Hayashi, F. Ushikubi, Y. Yokota, R. Kageyama, S. Nakanishi, and S. Narumiya Cloning and expression of cDNA for a human thromboxane A2 receptor Nature 349 1991 617 620
5. M.K. Raychowdhury, M. Yukawa, L.J. Collins, S.H. McGrail, K.C. Kent, and J.A. Ware Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A(2), receptor J. Biol. Chem. 269 1994 19256 19261
6. M. Walsh, J.F. Foley, and B.T. Kinsella Investigation of the role of the carboxyl-terminal tails of the alpha and beta isoforms of the human thromboxane A(2) receptor (TP) in mediating receptor:effector coupling Biochim. Biophys. Acta 1496 2000 164 182
7. Y. Gao, S. Tang, S. Zhou, and J.A. Ware The thromboxane A2 receptor activates mitogen-activated protein kinase via protein kinase C-dependent Gi coupling and Src-dependent phosphorylation of the epidermal growth factor receptor J. Pharmacol. Exp. Ther. 296 2001 426 433
8. S. Rodrigues, Q.D. Nguyen, S. Faivre, E. Bruyneel, L. Thim, B. Westley, F. May, G. Flatau, M. Mareel, C. Gespach, and S. Emami Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways FASEB J. 15 2001 1517 1528
9. S.M. Miggin, and B.T. Kinsella Regulation of extracellular signal-regulated kinase cascades by alpha- and beta-isoforms of the human thromboxane A(2) receptor Mol. Pharmacol. 61 2002 817 831
10. Z. Li, G. Zhang, G.C. Le Breton, X. Gao, A.B. Malik, and X. Du Two waves of platelet secretion induced by thromboxane A2 receptor, and a critical role for phosphoinositide 3-kinases J. Biol. Chem. 2003
11. C. Gallet, S. Blaie, S. Levy-Toledano, and A. Habib Epidermal-growth- factor receptor and metalloproteinases mediate thromboxane A2-dependent extracellular-signal-regulated kinase activation Biochem. J. 371 2003 733 742
12. 2 receptor is required for ERK2 activation in collagen-induced platelet aggregation FEBS Lett. 556 2004 227 235
13. M.D. Rochdi, V. Watier, C. La Madeleine, H. Nakata, T. Kozasa, and J.L. Parent Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50) J. Biol. Chem. 277 2002 40751 40759
14. M.D. Rochdi, and J.L. Parent Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50 J. Biol. Chem. 278 2003 17827 17837
15. J.L. Parent, P. Labrecque, M.D. Rochdi, and J.L. Benovic Role of the differentially spliced carboxyl terminus in thromboxane A2 receptor trafficking: identification of a distinct motif for tonic internalization J. Biol. Chem. 276 2001 7079 7085
16. S.M. Miggin, and B.T. Kinsella Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms Biochim. Biophys. Acta 1425 1998 543 559
17. 2α Br. J. Pharmacol. 119 1996 1276 1280
18. M.P. Reilly, D. Pratico, N. Delanty, G. DiMinno, E. Tremoli, D. Rader, S. Kapoor, J. Rokach, J. Lawson, and G.A. FitzGerald Increased formation of distinct F2 isoprostanes in hypercholesterolemia Circulation 98 1998 2822 2828
19. D. Pratico, L. Iuliano, A. Mauriello, L. Spagnoli, J.A. Lawson, J. Maclouf, F. Violi, and G.A. FitzGerald Localization of distinct F2-isoprostanes in human atherosclerotic lesions J. Clin. Invest. 100 1997 2028 2034
20. C. Vassalle, N. Botto, M.G. Andreassi, S. Berti, and A. Biagini Evidence for enhanced 8-isoprostane plasma levels, as index of oxidative stress in vivo, in patients with coronary artery disease Coron. Artery Dis. 14 2003 213 218
21. F. Valentin, M.C. Field, and J.R. Tippins The mechanism of oxidative stress stabilization of the thromboxane receptor in COS-7 cells J. Biol. Chem. 279 2004 8316 8324
22. G.W. Dorn, J.L. Trask, D.E. Mais, M.E. Assey, and P.V. Halushka Increased platelet thromboxane A2 prostaglandin H2 receptors in patients with acute myocardial infarction Circulation 81 1990 212 218
23. S.D. Katugampola, and A.P. Davenport Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT(1) receptor antagonist losartan Br. J. Pharmacol. 134 2001 1385 1392
24. S.D. Katugampola, R.E. Kuc, J.J. Maguire, and A.P. Davenport G-protein-coupled receptors in human atherosclerosis: comparison of vasoconstrictors (endothelin and thromboxane) with recently de-orphanized (urotensin-II, apelin and ghrelin) receptors Clin. Sci. (Lond.) 103 Suppl. 48 2002 171S 175S
25. B.T. Kinsella Thromboxane A2 signalling in humans: a 'Tail' of two receptors Biochem. Soc. Trans. 29 2001 641 654
26. R.Y. Hampton Proteolysis and sterol regulation Annu. Rev. Cell Dev. Biol. 18 2002 345 378
27. B.L. Song, and R.A. DeBose-Boyd Ubiquitination of 3-hydroxy-3- methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase J. Biol. Chem. 279 2004 28798 28806
28. H.H. Cheng, L. Xu, H. Kumagai, and R.D. Simoni Oligomerization state influences the degradation rate of 3-hydroxy-3-methylglutaryl-CoA reductase J. Biol. Chem. 274 1999 17171 17178