Development of transgenic alfalfa plants containing the foot and mouth disease virus structural polyprotein gene P1 and its utilization as an experimental immunogen

Vaccine

Volumn 23, Issue 15 SPEC. ISS., 2005, Pages 1838-1843

  Dus Santos, María J ^a   Carrillo, Consuelo ^b   Ardila, Fernando ^a   Ríos, Raúl D ^a   Franzone, Pascual ^a   Piccone, María E ^b   Wigdorovitz, Andrés ^a   Borca, Manuel V ^b  

^a INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA INTA   (Argentina)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Experimental vaccines; Foot and mouth disease virus; Transgenic plants

Indexed keywords

ANTIBODY; ANTIGEN; FOOT AND MOUTH DISEASE VACCINE; PLANT EXTRACT; POLYPROTEIN; PROTEINASE; STRUCTURAL PROTEIN;

ALFALFA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ISOLATION; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENETIC CODE; IMMUNIZATION; IMMUNOGENICITY; INFECTION PREVENTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; TRANSGENIC PLANT; VIRUS VIRULENCE;

EID: 14744305980     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.11.014     Document Type: Conference Paper

References (17)

1. T. Arakawa, D.K.X. Chong, and W.H.R. Langridge Efficacy of a food plant based oral cholera toxin B subunit vaccine Nat Biotechnol 16 1998 292 297
2. H.S. Mason, T.A. Haq, J.D. Clements, and C.J. Arntzen Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene Vaccine 16 1998 1335 1342
3. L.J. Ritcher, Y. Thanavala, C.J. Arntzen, and H.S. Mason Production of hepatitis B surface antigen in transgenic plants for oral immunization Nat Biotechnol 18 2000 1167 1171
4. C.O. Tacket, H.S. Mason, G. Losonsky, M.K. Estes, M.M. Levine, and C.J. Arntzen Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes J Infect Dis 182 2000 302 305
5. J. Yu, and W. Langridge A plant-based multicomponent vaccine protects mice from enteric diseases Nat Biotechnol 19 2001 548 552
6. A.M. Walmsley, D.D. Kirk, and H.S. Mason Passive immunization of mice pups through oral immunization of dams with a plant-derived vaccine Immunol Lett 86 2003 71 76
7. P. Sojikul, N. Buehner, and H.S. Mason A plant signal peptide-hepatitis B surface antigen fusion protein with enhanced stability and immunogenicity expressed in plant cells Proc Natl Acad Sci USA 100 2003 2209 2214 [Epub 2003 Feb 24]
8. J.M. Martin-Alonso, S. Castanon, P. Alonso, F. Parra, and R. Ordas Oral immunization using tuber extracts from transgenic potato plants expressing rabbit hemorrhagic disease virus capsid protein Trans Res 12 2003 127 130
9. A.M. Walmsley, M.L. Alvarez, Y. Jin, D.D. Kirk, S.M. Lee, and J. Pinkhasov Expression of the B subunit of Escherichia coli heat-labile enterotoxin as a fusion protein in transgenic tomato Plant Cell Rep 21 2003 1020 1026 [Epub 2003 Apr 11]
10. A. Varsani, A.L. Williamson, R.C. Rose, M. Jaffer, and E.P. Rybicki Expression of human papillomavirus type 16 major capsid protein in transgenic nicotiana tabacum cv Xanthi Arch Virol 148 2003 1771 1786
11. F. Brown Vaccination against foot and mouth disease virus Vaccine 10 1992 1022 1026
12. C. Carrillo, A. Wigdorovitz, J.C. Oliveros, P.I. Zamorano, A.M. Sadir, and N. Gómez Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants J Virol 72 1998 1688 1690
13. A. Wigdorovitz, C. Carrillo, M.J. Dus Santos, A.M. Sadir, R. Rios, and P. Franzone Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunized with alfalfa transgenic plants expressing the viral structural protein VP1 Virology 255 1999 347 353
14. C. Carrillo, A. Wigdorovitz, K. Trono, M.J. Dus Santos, A.M. Sadir, and F. Parra Induction of a virus specific antibody response to foot and mouth disease virus using the structural protein VP1 expressed in transgenic potatoes plants Virol Immunol 14 2001 49 57
15. M.J. Dus Santos, A. Wigdorovitz, K. Trono, F. Gil, R. Rios, and P. Franzone A novel methodology to develop a FMDV peptide based vaccine in transgenic plants Vaccine 20 2002 1141 1147
16. M.J. Dus Santos, A. Wigdorovitz, O. Periolo, E. Maradei, M.V. Borca, and A.M. Sadir A comparison of methods for measuring the antibody response in mice and cattle following vaccination against foot and mouth disease Vet Res Commun 24 2000 261 273
17. P.W. Mason, J. Chinsangaram, M.P. Moraes, G.A. Mayr, and M.J. Grubman Engineering better vaccines for foot-and-mouth disease Dev Biol (Basel) 114 2003 79 88