메뉴 건너뛰기




Volumn 4, Issue 1, 2005, Pages 35-50

Epidemiologic, immunologic and practical considerations in developing and evaluating a human hookworm vaccine

Author keywords

Hookworm; Recombinant vaccine

Indexed keywords

ALBENDAZOLE; ALUMINUM HYDROXIDE; ANTHELMINTIC AGENT; BENZIMIDAZOLE DERIVATIVE; COMPLEMENTARY DNA; HOOKWORM VACCINE; MEBENDAZOLE; PRAZIQUANTEL; RECOMBINANT ANTIGEN; RECOMBINANT ASP2 ANTIGEN; TIABENDAZOLE; UNCLASSIFIED DRUG;

EID: 14744280289     PISSN: 14760584     EISSN: None     Source Type: Journal    
DOI: 10.1586/14760584.4.1.35     Document Type: Review
Times cited : (37)

References (101)
  • 1
    • 0346056892 scopus 로고    scopus 로고
    • Malaria vaccine developments
    • Moorthy VS, Good MF, Hill AV. Malaria vaccine developments. Lancet 363, 150-156 (2004).
    • (2004) Lancet , vol.363 , pp. 150-156
    • Moorthy, V.S.1    Good, M.F.2    Hill, A.V.3
  • 4
    • 0042827212 scopus 로고    scopus 로고
    • Progress in the development of a recombinant vaccine for human hookworm disease: The human hookworm vaccine initiative
    • Hotez PJ, Zhan B, Bethony JM et al. Progress in the development of a recombinant vaccine for human hookworm disease: the human hookworm vaccine initiative. Int. J. Parasitol. 33, 1245-1258 (2003).
    • (2003) Int. J. Parasitol. , vol.33 , pp. 1245-1258
    • Hotez, P.J.1    Zhan, B.2    Bethony, J.M.3
  • 5
    • 0345293239 scopus 로고    scopus 로고
    • Soil-transmitted helminth infections: Updating the global picture
    • de Silva NR, Brooker S, Hotez PJ et al. Soil-transmitted helminth infections: updating the global picture. Trends Parasitol. 19, 547-551 (2003).
    • (2003) Trends Parasitol. , vol.19 , pp. 547-551
    • De Silva, N.R.1    Brooker, S.2    Hotez, P.J.3
  • 7
    • 65349105779 scopus 로고    scopus 로고
    • Annex Table 3, Burden of disease in DALYs by cause, sex and mortality stratum in WHO Regions, estimates for 2001
    • World Health Organization, Geneva
    • WHO. Annex Table 3, Burden of disease in DALYs by cause, sex and mortality stratum in WHO Regions, estimates for 2001. In: The World Health Report 2002, Reducing Risks, Promoting Health Life. World Health Organization, Geneva, 192-193 (2002).
    • (2002) The World Health Report 2002, Reducing Risks, Promoting Health Life , pp. 192-193
  • 8
    • 0006072935 scopus 로고    scopus 로고
    • Prevention and control of schistosomiasis and soil-transmitted helminthiases. WHO Technical Report Series 912
    • Geneva
    • WHO. Prevention and control of schistosomiasis and soil-transmitted helminthiases. WHO Technical Report Series 912. World Health Organization, Geneva, 2 (2002).
    • (2002) World Health Organization , pp. 2
  • 9
    • 0017887292 scopus 로고
    • Necator americanus and Ancylostoma duodenale: Life history parameters and epidemiological implications of two sympatric hookworms of humans
    • Hoagland KE, Schad GA. Necator americanus and Ancylostoma duodenale: life history parameters and epidemiological implications of two sympatric hookworms of humans. Exp. Parasitol. 44, 36-49 (1978).
    • (1978) Exp. Parasitol. , vol.44 , pp. 36-49
    • Hoagland, K.E.1    Schad, G.A.2
  • 10
    • 0002127163 scopus 로고
    • Hookworm infection, nutritional status and productivity
    • Schad GA, Warren KS (Eds). Taylor and Francis, London, UK
    • Crompton DWT, Stephenson LS. Hookworm infection, nutritional status and productivity. In: Hookworm Disease Current Status and New Directions. Schad GA, Warren KS (Eds). Taylor and Francis, London, UK, 231-264 (1990).
    • (1990) Hookworm Disease Current Status and New Directions , pp. 231-264
    • Crompton, D.W.T.1    Stephenson, L.S.2
  • 11
    • 0031014002 scopus 로고    scopus 로고
    • Epidemiology of iron-deficiency anemia in Zanzibari schoolchildren: The importance of hookworms
    • Stoltzfus RJ, Chwaya HM, Tielsch JM et al. Epidemiology of iron-deficiency anemia in Zanzibari schoolchildren: the importance of hookworms. Am. J. Clin. Nutr. 65, 153-159 (1997).
    • (1997) Am. J. Clin. Nutr. , vol.65 , pp. 153-159
    • Stoltzfus, R.J.1    Chwaya, H.M.2    Tielsch, J.M.3
  • 12
    • 0025274961 scopus 로고
    • Benzimidoles in a wormy world
    • Horton RJ. Benzimidoles in a wormy world. Parasitol. Today 6, 106 (1990).
    • (1990) Parasitol. Today , vol.6 , pp. 106
    • Horton, R.J.1
  • 13
    • 0025267185 scopus 로고
    • Mode of action of benzimidazoles
    • Lacey E. Mode of action of Benzimidazoles. Parasitol. Today 6, 112-115 (1990).
    • (1990) Parasitol. Today , vol.6 , pp. 112-115
    • Lacey, E.1
  • 14
    • 1242296814 scopus 로고    scopus 로고
    • Schistosomiasis and soil-transmitted helminthiasis: Common drugs for treatment and control
    • Utzinger J, Keiser J. Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control. Expert Opin. Pharmaco. 5, 263-286 (2004). Reviews the development, current experience and future prospects of human anthelmintic chemotherapy.
    • (2004) Expert Opin. Pharmaco. , vol.5 , pp. 263-286
    • Utzinger, J.1    Keiser, J.2
  • 15
    • 0034142307 scopus 로고    scopus 로고
    • Reducing intestinal nematode infection: Efficacy of albendazole and mebendazole
    • Bennett A, Guyatt H. Reducing intestinal nematode infection: efficacy of albendazole and mebendazole. Parasitol. Today 16, 71-74 (2000). Analyzes published data on cure rates and egg reduction rates of mebendazole and albendazole for treating intestinal nematode infections in humans.
    • (2000) Parasitol. Today , vol.16 , pp. 71-74
    • Bennett, A.1    Guyatt, H.2
  • 16
    • 0034439133 scopus 로고    scopus 로고
    • Albendazole: A review of anthelmintic efficacy and safety in humans
    • Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology 121, S113-S132 (2000). Summarizes the efficacy and safety of albendazole's use as an anthelminthic in humans.
    • (2000) Parasitology , vol.121
    • Horton, J.1
  • 17
    • 0034772196 scopus 로고    scopus 로고
    • Anthelmintic resistance in human helminths: A review
    • Geerts S, Gryseels B. Anthelmintic resistance in human helminths: a review. Trop. Med. Int. Health 6, 915-921 (2001). Critically analyzes reports on drug resistance in human helminths and reviews experiences with helminths of livestock.
    • (2001) Trop. Med. Int. Health , vol.6 , pp. 915-921
    • Geerts, S.1    Gryseels, B.2
  • 18
    • 0037726601 scopus 로고    scopus 로고
    • Impact of chemotherapy on the morbidity due to soil-transmitted nematodes
    • de Silva NR. Impact of chemotherapy on the morbidity due to soil-transmitted nematodes. Acta Trop. 96, 197-214 (2003).
    • (2003) Acta Trop. , vol.96 , pp. 197-214
    • De Silva, N.R.1
  • 19
    • 10444241029 scopus 로고    scopus 로고
    • Human hookworm infection in the 21st century
    • Brooker S, Bethony J, Hotez PJ. Human hookworm infection in the 21st century. Adv. Parasitol. 58, 197-288 (2004).
    • (2004) Adv. Parasitol. , vol.58 , pp. 197-288
    • Brooker, S.1    Bethony, J.2    Hotez, P.J.3
  • 20
    • 0031045601 scopus 로고    scopus 로고
    • Better health, nutrition and education for the school-aged child
    • Partnership for Child Development. Better health, nutrition and education for the school-aged child. Trans. R. Soc. Trop. Med. Hyg. 91, 1-2 (1997).
    • (1997) Trans. R. Soc. Trop. Med. Hyg. , vol.91 , pp. 1-2
  • 21
    • 0344947564 scopus 로고    scopus 로고
    • Schistosomiasis and soil-transmitted helminth infections: Forging control efforts
    • Savioli L, Stansfield S, Bundy DAP et al. Schistosomiasis and soil-transmitted helminth infections: forging control efforts. Trans. R. Soc. Trop. Med. Hyg. 96, 577-579 (2002).
    • (2002) Trans. R. Soc. Trop. Med. Hyg. , vol.96 , pp. 577-579
    • Savioli, L.1    Stansfield, S.2    Bundy, D.A.P.3
  • 22
    • 0028851648 scopus 로고
    • Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area
    • Albonico M, Smith PG, Ercole E et al. Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area. Trans. R. Soc. Trop. Med. Hyg. 89, 538-541 (1995).
    • (1995) Trans. R. Soc. Trop. Med. Hyg. , vol.89 , pp. 538-541
    • Albonico, M.1    Smith, P.G.2    Ercole, E.3
  • 23
    • 0027287708 scopus 로고
    • Reinfection with hookworm after chemotherapy in Papua New Guinea
    • Quinnell RJ, Slater AFG, Tighe P et al. Reinfection with hookworm after chemotherapy in Papua New Guinea. Parasitology 106, 379-385 (1993).
    • (1993) Parasitology , vol.106 , pp. 379-385
    • Quinnell, R.J.1    Slater, A.F.G.2    Tighe, P.3
  • 24
    • 0021875922 scopus 로고
    • Community control of helminth infections of man by mass and selective chemotherapy
    • Anderson RM, Medley GF. Community control of helminth infections of man by mass and selective chemotherapy. Parasitology 90, 629-660 (1985).
    • (1985) Parasitology , vol.90 , pp. 629-660
    • Anderson, R.M.1    Medley, G.F.2
  • 25
    • 0031434430 scopus 로고    scopus 로고
    • Transmission patterns and the epidemiology of hookworm
    • Chan MS, Bradley M, Bundy DAP. Transmission patterns and the epidemiology of hookworm. Int. J. Epidemiol. 26, 1392-1400 (1997). Describes models of hookworm transmission dynamics where school-based, adult- and population-targeted chemotherapy programs are compared.
    • (1997) Int. J. Epidemiol. , vol.26 , pp. 1392-1400
    • Chan, M.S.1    Bradley, M.2    Bundy, D.A.P.3
  • 26
    • 0028023473 scopus 로고
    • Vaccines or drugs: Complementarity is crucial
    • Tanner M, Evans D. Vaccines or drugs: complementarity is crucial. Parasitol. Today 10, 196-202 (1994).
    • (1994) Parasitol. Today , vol.10 , pp. 196-202
    • Tanner, M.1    Evans, D.2
  • 27
    • 0034110649 scopus 로고    scopus 로고
    • Drug resistance in human helminths: Current situation and lessons from livestock
    • Geerts S, Gryseels B. Drug resistance in human helminths: current situation and lessons from livestock. Clin. Microbiol. Rev. 13, 207-222 (2000).
    • (2000) Clin. Microbiol. Rev. , vol.13 , pp. 207-222
    • Geerts, S.1    Gryseels, B.2
  • 28
    • 0030797492 scopus 로고    scopus 로고
    • Failure of mebendazole in treatment of human hookworm infection in the southern region of Mali
    • de Clerq D, Sacko M, Behnke J et al. Failure of mebendazole in treatment of human hookworm infection in the southern region of Mali. Am. J. Trop. Med. Hyg. 57, 25-30 (1997).
    • (1997) Am. J. Trop. Med. Hyg. , vol.57 , pp. 25-30
    • De Clerq, D.1    Sacko, M.2    Behnke, J.3
  • 29
    • 0031446782 scopus 로고    scopus 로고
    • Failure of pyrantel in treatment of human hookworm infection (Ancylostoma duodenale) in the Kimberely region of North West Australia
    • Reynoldson JA, Behnke JM, Pallant LJ et al. Failure of pyrantel in treatment of human hookworm infection (Ancylostoma duodenale) in the Kimberely region of North West Australia. Acta Tropica 68, 301-312 (1997).
    • (1997) Acta Tropica , vol.68 , pp. 301-312
    • Reynoldson, J.A.1    Behnke, J.M.2    Pallant, L.J.3
  • 30
    • 0037899938 scopus 로고    scopus 로고
    • Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar
    • Albonico M, Bickle Q, Ramsan M et al. Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar. Bull. WHO 81, 343-352 (2003). Provide field data on the reduced efficacy of anthelminthic following repeated rounds of treatment.
    • (2003) Bull. WHO , vol.81 , pp. 343-352
    • Albonico, M.1    Bickle, Q.2    Ramsan, M.3
  • 31
    • 0041828329 scopus 로고    scopus 로고
    • Global anthelmintic chemotherapy programs: Learning from history
    • Horton J. Global anthelmintic chemotherapy programs: learning from history. Trends Parasitol. 19, 405-409 (2003).
    • (2003) Trends Parasitol. , vol.19 , pp. 405-409
    • Horton, J.1
  • 32
    • 0029012685 scopus 로고
    • The practicality and sustainability of vaccination as an approach to parasite control
    • Bundy DAP, Chan MS, Guyatt HL. The practicality and sustainability of vaccination as an approach to parasite control. Parasitology 110, S51-S58 (1995). Reviews the understanding of parasite population dynamics and epidemiology and how these influence the feasibility and sustainability of any new vaccine.
    • (1995) Parasitology , vol.110
    • Bundy, D.A.P.1    Chan, M.S.2    Guyatt, H.L.3
  • 34
    • 0001784230 scopus 로고
    • The population dynamics and control of hookworm and roundworm infection
    • Anderson RM (Ed.). Chapman and Hall, London, UK
    • Anderson RM. The population dynamics and control of hookworm and roundworm infection. In: Population Dynamics of Infectious Diseases: Theory and Applications. Anderson RM (Ed.). Chapman and Hall, London, UK, 67-109 (1982).
    • (1982) Population Dynamics of Infectious Diseases: Theory and Applications , pp. 67-109
    • Anderson, R.M.1
  • 35
    • 0026525716 scopus 로고
    • Immunoepidemiology of human geohelminthiasis: Ecological and immunological determinants of worm burden
    • Bundy DAP, Medley GE Immunoepidemiology of human geohelminthiasis: ecological and immunological determinants of worm burden. Parasitology 104, S105-S119 (1992).
    • (1992) Parasitology , vol.104
    • Bundy, D.A.P.1    Medley, G.E.2
  • 36
    • 8744310145 scopus 로고    scopus 로고
    • Epidemiology of helminth infections and their relationship to clinical malaria in southwest Uganda
    • Shapiro AE, Tukahebwa EM, Kasten J et al. Epidemiology of helminth infections and their relationship to clinical malaria in southwest Uganda. Trans. R. Soc. Trop. Med. Hyg. 99, 18-24 (2005).
    • (2005) Trans. R. Soc. Trop. Med. Hyg. , vol.99 , pp. 18-24
    • Shapiro, A.E.1    Tukahebwa, E.M.2    Kasten, J.3
  • 37
    • 0027519733 scopus 로고
    • Antischistosomal vaccines: Beyond the laboratory
    • Basch PF. Antischistosomal vaccines: beyond the laboratory. Trans. Roy. Soc. Trop. Med. Hyg. 87, 589-592 (1993).
    • (1993) Trans. Roy. Soc. Trop. Med. Hyg. , vol.87 , pp. 589-592
    • Basch, P.F.1
  • 38
    • 0027839480 scopus 로고
    • Herd immunity: History, theory, practice
    • Fine PEM. Herd immunity: history, theory, practice. Epidemiol Rev. 15(2), 265-302 (1993).
    • (1993) Epidemiol Rev. , vol.15 , Issue.2 , pp. 265-302
    • Fine, P.E.M.1
  • 39
    • 0034767749 scopus 로고    scopus 로고
    • Immune responses in hookworm infections
    • Loukas A, Prociv P. Immune responses in hookworm infections. Clin. Microbiol. Rev. 14, 689-703 (2001). Thorough review of hookworm biology, immune responses against the different parasitic stages and parasite mechanisms to escape the host's immune response.
    • (2001) Clin. Microbiol. Rev. , vol.14 , pp. 689-703
    • Loukas, A.1    Prociv, P.2
  • 40
    • 0023123039 scopus 로고
    • Antigen expression during development of the human hookworm, Necator americanus (Nematoda)
    • Carr A, Pritchard DI. Antigen expression during development of the human hookworm, Necator americanus (Nematoda). Parasite Immunol. 9, 219-234 (1987).
    • (1987) Parasite Immunol. , vol.9 , pp. 219-234
    • Carr, A.1    Pritchard, D.I.2
  • 41
    • 0026448737 scopus 로고
    • Isotypic variation in antibody responses in a community in Papua New Guinea to larval and adult antigens during infection, and following reinfection, with the hookworm Necator americanus
    • Pritchard DI, Walsh EA, Quinnell RJ et al. Isotypic variation in antibody responses in a community in Papua New Guinea to larval and adult antigens during infection, and following reinfection, with the hookworm Necator americanus. Parasite Immunol. 6, 617-631 (1992).
    • (1992) Parasite Immunol. , vol.6 , pp. 617-631
    • Pritchard, D.I.1    Walsh, E.A.2    Quinnell, R.J.3
  • 43
    • 0032696178 scopus 로고    scopus 로고
    • Infection and disease in human Schistosomiasis mansoni are under distinct major gene control
    • Dessein AJ, Marquet S, Henri S et al. Infection and disease in human Schistosomiasis mansoni are under distinct major gene control. Microbes Infect. 1, 561-567 (1999).
    • (1999) Microbes Infect. , vol.1 , pp. 561-567
    • Dessein, A.J.1    Marquet, S.2    Henri, S.3
  • 44
    • 0036095758 scopus 로고    scopus 로고
    • Infection with Schistosoma mansoni correlates with altered immune responses to Ascaris lumbricoides and hookworm
    • Corrêa-Oliveira R, Golgher DB, Oliveira GC et al. Infection with Schistosoma mansoni correlates with altered immune responses to Ascaris lumbricoides and hookworm. Acta Trop. 83, 123-132 (2002).
    • (2002) Acta Trop. , vol.83 , pp. 123-132
    • Corrêa-Oliveira, R.1    Golgher, D.B.2    Oliveira, G.C.3
  • 45
    • 0016396471 scopus 로고
    • Elevation of total serum IgE in rats following helminth parasite infection
    • Jarrett E, Bazin H. Elevation of total serum IgE in rats following helminth parasite infection. Nature 251 (5476), 613-614 (1974).
    • (1974) Nature , vol.251 , Issue.5476 , pp. 613-614
    • Jarrett, E.1    Bazin, H.2
  • 46
    • 0028928711 scopus 로고
    • Immunity in humans to Necator americanus: IgE, parasite weight and fecundity
    • Pritchard DI, Quinnell RJ, Walsh EA. Immunity in humans to Necator americanus: IgE, parasite weight and fecundity. Parasite Immunol. 2, 71-75 (1995).
    • (1995) Parasite Immunol. , vol.2 , pp. 71-75
    • Pritchard, D.I.1    Quinnell, R.J.2    Walsh, E.A.3
  • 47
    • 0027180578 scopus 로고
    • Atopy and helminth parasites
    • Pritchard DI. Atopy and helminth parasites. Int. J. Parasitol. 2, 167-168 (1993).
    • (1993) Int. J. Parasitol. , vol.2 , pp. 167-168
    • Pritchard, D.I.1
  • 48
    • 0035305904 scopus 로고    scopus 로고
    • Is Necator americanus approaching a mutualistic symbiotic relationship with humans?
    • Pritchard DI, Brown A. Is Necator americanus approaching a mutualistic symbiotic relationship with humans? Trends Parasitol. 4, 169-172 (2001)
    • (2001) Trends Parasitol. , vol.4 , pp. 169-172
    • Pritchard, D.I.1    Brown, A.2
  • 49
  • 50
    • 2142711132 scopus 로고    scopus 로고
    • Cellular responses and cytokine production in post-treatment hookworm patients from an endemic area in Brazil
    • Geiger SM, Massara CL, Bethony J, Soboslay PT, Correa-Oliveira R. Cellular responses and cytokine production in post-treatment hookworm patients from an endemic area in Brazil. Clin. Exp. Immunol. 2, 334-340 (2004).
    • (2004) Clin. Exp. Immunol. , vol.2 , pp. 334-340
    • Geiger, S.M.1    Massara, C.L.2    Bethony, J.3    Soboslay, P.T.4    Correa-Oliveira, R.5
  • 51
    • 3242776207 scopus 로고    scopus 로고
    • Immune responses in human necatoriasis: Association between interleukin-5 responses and resistance to reinfection
    • Quinnell RJ, Pritchard DI, Raiko A, Brown AP, Shaw MA. Immune responses in human necatoriasis: association between interleukin-5 responses and resistance to reinfection. J. Infect. Dis. 190(3), 430-438 (2004). One of the first articles evaluating the cellular immune response against hookworm infection and during reinfection. Associates interleukin-5 secretion in peripheral blood mononuclear cells with resistance to reinfection.
    • (2004) J. Infect. Dis. , vol.190 , Issue.3 , pp. 430-438
    • Quinnell, R.J.1    Pritchard, D.I.2    Raiko, A.3    Brown, A.P.4    Shaw, M.A.5
  • 52
    • 4844229387 scopus 로고    scopus 로고
    • Helminth parasites - Masters of regulation
    • Maizels RM, Balic A, Gomez-Escobar N et al. Helminth parasites - masters of regulation. Immunol. Rev. 201, 89-116 (2004). State-of-the-art review regarding the knowledge in immunoregulation due to helminth parasites. Integrates experimental models with human studies and attempts to shed some light on the complex cytokine network and the parasite-host interactions.
    • (2004) Immunol. Rev. , vol.201 , pp. 89-116
    • Maizels, R.M.1    Balic, A.2    Gomez-Escobar, N.3
  • 53
    • 1342324588 scopus 로고    scopus 로고
    • The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells
    • Hesse M, Piccirillo CA, Belkaid Y et al. The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells. J. Immunol. 5, 3157-3166 (2004).
    • (2004) J. Immunol. , vol.5 , pp. 3157-3166
    • Hesse, M.1    Piccirillo, C.A.2    Belkaid, Y.3
  • 54
    • 0032745930 scopus 로고    scopus 로고
    • Antibody-dependent reductions in mouse hookworm burden after vaccination with Ancylostoma caninum secreted protein 1
    • Ghosh K, Hotez PJ. Antibody-dependent reductions in mouse hookworm burden after vaccination with Ancylostoma caninum secreted protein 1. J. Infect. Dis. 5, 1674-1681 (1999).
    • (1999) J. Infect. Dis. , vol.5 , pp. 1674-1681
    • Ghosh, K.1    Hotez, P.J.2
  • 55
    • 12244275041 scopus 로고    scopus 로고
    • Successful vaccination of BALB/c mice against human hookworm (Necator americanus): The immunological phenotype of the protective response
    • Girod N, Brown A, Pritchard DI, Billett EE. Successful vaccination of BALB/c mice against human hookworm (Necator americanus): the immunological phenotype of the protective response. Int. J. Parasitol. 1, 71-80 (2003).
    • (2003) Int. J. Parasitol. , vol.1 , pp. 71-80
    • Girod, N.1    Brown, A.2    Pritchard, D.I.3    Billett, E.E.4
  • 56
    • 0032696177 scopus 로고    scopus 로고
    • Strategies for a schistosome vaccine: Can we manipulate the immune response effectively?
    • Wilson AR, Coulson PS. Strategies for a schistosome vaccine: can we manipulate the immune response effectively? Microbes Infect. 1, 535-543 (1999).
    • (1999) Microbes Infect. , vol.1 , pp. 535-543
    • Wilson, A.R.1    Coulson, P.S.2
  • 57
    • 0035111178 scopus 로고    scopus 로고
    • Effect of deworming on human T-cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacillus Calmette-Guerin (BCG) vaccination
    • Elias D, Wolday D, Akuffo H et al. Effect of deworming on human T-cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacillus Calmette-Guerin (BCG) vaccination. Clin. Exp. Immunol. 123, 219-225 (2001).
    • (2001) Clin. Exp. Immunol. , vol.123 , pp. 219-225
    • Elias, D.1    Wolday, D.2    Akuffo, H.3
  • 58
    • 0033956299 scopus 로고    scopus 로고
    • The human hookworm pathogen Necator americanus induces apoptosis in T-lymphocytes
    • Chow SC, Brown A, Pritchard D. The human hookworm pathogen Necator americanus induces apoptosis in T-lymphocytes. Parasite Immunol. 1, 21-29 (2000). Important article for the discovery of molecules and mechanisms through which hookworms may evade the host's immune system. Demonstrates that the parasites can disarm host effector mechanisms or redirect the immune response in order to create a site of immune privilege.
    • (2000) Parasite Immunol. , vol.1 , pp. 21-29
    • Chow, S.C.1    Brown, A.2    Pritchard, D.3
  • 59
    • 0034547887 scopus 로고    scopus 로고
    • Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo
    • Culley FJ, Brown A, Conroy DM et al. Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo. J. Immunol. 11, 6447-6453 (2000). Important article for the discovery of molecules and mechanisms through which hookworms may evade the host's immune system. Demonstrates that the parasites can disarm host effector mechanisms or redirect the immune response in order to create a site of immune privilege.
    • (2000) J. Immunol. , vol.11 , pp. 6447-6453
    • Culley, F.J.1    Brown, A.2    Conroy, D.M.3
  • 60
    • 4043095493 scopus 로고    scopus 로고
    • A secreted protein from the human hookworm Necator americanus binds selectively to NK cells and induces IFN-γ production
    • Hsieh GC, Loukas A, Wahl AM et al. A secreted protein from the human hookworm Necator americanus binds selectively to NK cells and induces IFN-γ production. J. Immunol. 173(4), 2699-2704 (2004). Important article for the discovery of molecules and mechanisms through which hookworms may evade the host's immune system. Demonstrates that the parasites can disarm host effector mechanisms or redirect the immune response in order to create a site of immune privilege.
    • (2004) J. Immunol. , vol.173 , Issue.4 , pp. 2699-2704
    • Hsieh, G.C.1    Loukas, A.2    Wahl, A.M.3
  • 61
    • 0030272242 scopus 로고    scopus 로고
    • Hookworm: Developmental biology of the infectious process
    • Hawdon JM, Hotez PJ. Hookworm: developmental biology of the infectious process. Curr. Opin. Genet. Dev. 6, 618-623 (1996).
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 618-623
    • Hawdon, J.M.1    Hotez, P.J.2
  • 63
  • 64
    • 0035341708 scopus 로고    scopus 로고
    • Mitigation of hookworm disease by immunization with soluble extracts of Ancylostoma ceylanicum
    • Bungito RD, Green J, Kruglov E, Cappello M. Mitigation of hookworm disease by immunization with soluble extracts of Ancylostoma ceylanicum. J. Infect. Dis. 183, 1380-1387 (2001).
    • (2001) J. Infect. Dis. , vol.183 , pp. 1380-1387
    • Bungito, R.D.1    Green, J.2    Kruglov, E.3    Cappello, M.4
  • 65
    • 0031802959 scopus 로고    scopus 로고
    • Profound suppression of cellular proliferation mediated by the secretions of nematodes
    • Allen JE, MacDonald AS. Profound suppression of cellular proliferation mediated by the secretions of nematodes. Parasite Immunol. 20, 241-247 (1998).
    • (1998) Parasite Immunol. , vol.20 , pp. 241-247
    • Allen, J.E.1    MacDonald, A.S.2
  • 66
    • 0018062307 scopus 로고
    • Industrial development and field use of the canine hookworm vaccine
    • Miller TA. Industrial development and field use of the canine hookworm vaccine. Adv. Parasitol. 16, 333-342 (1978).
    • (1978) Adv. Parasitol. , vol.16 , pp. 333-342
    • Miller, T.A.1
  • 67
    • 0032726958 scopus 로고    scopus 로고
    • Experimental approaches to the development of a recombinant hookworm vaccine
    • Hotez PJ, Ghosh K, Hawdon JM et al. Experimental approaches to the development of a recombinant hookworm vaccine. Immunol. Rev. 171, 163-171 (1999).
    • (1999) Immunol. Rev. , vol.171 , pp. 163-171
    • Hotez, P.J.1    Ghosh, K.2    Hawdon, J.M.3
  • 68
    • 0032934497 scopus 로고    scopus 로고
    • Ancylostoma secreted protein 2: Cloning and characterization of a second member of a family of nematode-secreted proteins from Ancylostoma caninum
    • Hawdon JM, Narasmihan S, Hotez PJ. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode-secreted proteins from Ancylostoma caninum. Mol. Biochem. Parasitol. 30, 149-165 (1999).
    • (1999) Mol. Biochem. Parasitol. , vol.30 , pp. 149-165
    • Hawdon, J.M.1    Narasmihan, S.2    Hotez, P.J.3
  • 69
    • 12144287751 scopus 로고    scopus 로고
    • Cloning, yeast expression, isolation and vaccine testing of recombinant Ancylostoma-secreted protein 1 (ASP-1) and ASP-2 from Ancylostoma ceylanicum
    • Goud GN, Zhan B, Ghosh K et al. Cloning, yeast expression, isolation and vaccine testing of recombinant Ancylostoma-secreted protein 1 (ASP-1) and ASP-2 from Ancylostoma ceylanicum. J. Infect. Dis. 189, 919-929 (2004).
    • (2004) J. Infect. Dis. , vol.189 , pp. 919-929
    • Goud, G.N.1    Zhan, B.2    Ghosh, K.3
  • 70
    • 20144387080 scopus 로고    scopus 로고
    • Effect of combining the larval antigens Ancylostoma-secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum
    • In Press
    • Mendez S, Zhan B, Goud G et al. Effect of combining the larval antigens Ancylostoma-secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine (2005) (In Press).
    • (2005) Vaccine
    • Mendez, S.1    Zhan, B.2    Goud, G.3
  • 72
    • 4143121138 scopus 로고    scopus 로고
    • Ac-SAA-1 an immunodominant 16-kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum
    • Zhan B, Wang Y, Liu YY et al. Ac-SAA-1 an immunodominant 16-kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. Int. J. Parasitol. 34, 1037-1045 (2004).
    • (2004) Int. J. Parasitol. , vol.34 , pp. 1037-1045
    • Zhan, B.1    Wang, Y.2    Liu, Y.Y.3
  • 73
    • 0037046107 scopus 로고    scopus 로고
    • A developmentally regulated metalloprotease secreted by host stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases
    • Zhan B, Hotez PJ, Wang Y, Hawdon J. A developmentally regulated metalloprotease secreted by host stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Mol. Bio. Parasitol. 120, 291-296 (2002).
    • (2002) Mol. Bio. Parasitol. , vol.120 , pp. 291-296
    • Zhan, B.1    Hotez, P.J.2    Wang, Y.3    Hawdon, J.4
  • 74
    • 4143054944 scopus 로고    scopus 로고
    • A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms
    • Williamson AL, Lecchi P, Turk BE et al. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J. Bio. Chem. 279, 35950-35957 (2004).
    • (2004) J. Bio. Chem. , vol.279 , pp. 35950-35957
    • Williamson, A.L.1    Lecchi, P.2    Turk, B.E.3
  • 76
    • 2442680125 scopus 로고    scopus 로고
    • Vaccination of dogs with recombinant cysteine protease from the intestine of canine hookworms diminishes fecundity and growth of worms
    • Loukas A, Bethony JM, Williamson AL et al. Vaccination of dogs with recombinant cysteine protease from the intestine of canine hookworms diminishes fecundity and growth of worms. J. Infect. Dis. 189, 1952-1961 (2004).
    • (2004) J. Infect. Dis. , vol.189 , pp. 1952-1961
    • Loukas, A.1    Bethony, J.M.2    Williamson, A.L.3
  • 77
    • 4143054944 scopus 로고    scopus 로고
    • A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms
    • Williamson AL, Lecchi P, Turk BE et al. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J. Biol. Chem. 279, 35950-35957 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 35950-35957
    • Williamson, A.L.1    Lecchi, P.2    Turk, B.E.3
  • 78
    • 0036139151 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms
    • Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Mol. Biochem. Parasitol. 119, 107-116 (2002).
    • (2002) Mol. Biochem. Parasitol. , vol.119 , pp. 107-116
    • Jones, B.F.1    Hotez, P.J.2
  • 80
    • 0023275137 scopus 로고
    • Evaluating interventions against tropical diseases
    • Smith PG. Evaluating interventions against tropical diseases. Int. J. Epidemiol. 16, 159-166 (1987).
    • (1987) Int. J. Epidemiol. , vol.16 , pp. 159-166
    • Smith, P.G.1
  • 81
    • 0030045041 scopus 로고    scopus 로고
    • Evaluating new vaccines for developing countries. Efficacy or effectiveness?
    • Clemens J, Brenner R, Rao M, Tafari N, Lowe C. Evaluating new vaccines for developing countries. Efficacy or effectiveness? JAMA 275, 390-397 (1996).
    • (1996) JAMA , vol.275 , pp. 390-397
    • Clemens, J.1    Brenner, R.2    Rao, M.3    Tafari, N.4    Lowe, C.5
  • 82
    • 0032736845 scopus 로고    scopus 로고
    • Preparation for a pneumococcal vaccine trial in The Gambia: Individual or community randomisation?
    • Jaffar S, Leach A, Hall AJ et al. Preparation for a pneumococcal vaccine trial in The Gambia: individual or community randomisation? Vaccine 18, 633-640 (2000).
    • (2000) Vaccine , vol.18 , pp. 633-640
    • Jaffar, S.1    Leach, A.2    Hall, A.J.3
  • 83
    • 0033891962 scopus 로고    scopus 로고
    • Design and analysis issues in cluster-randomized trials of interventions against infectious diseases
    • Hayes RJ, Alexander ND, Bennett S, Cousens SN. Design and analysis issues in cluster-randomized trials of interventions against infectious diseases. Stats. Methods Med. Res. 9(2), 95-116 (2000).
    • (2000) Stats. Methods Med. Res. , vol.9 , Issue.2 , pp. 95-116
    • Hayes, R.J.1    Alexander, N.D.2    Bennett, S.3    Cousens, S.N.4
  • 84
    • 0036330433 scopus 로고    scopus 로고
    • Practical and ethical issues in the development of a vaccine against Schistosomiasis mansoni
    • Todd CW, Colley DG. Practical and ethical issues in the development of a vaccine against Schistosomiasis mansoni. Am. J. Trop. Med. Hyg. 66, 348-358 (2002). Discusses desired characteristics of a schistosomal vaccine and the practical steps required to develop such a vaccine.
    • (2002) Am. J. Trop. Med. Hyg. , vol.66 , pp. 348-358
    • Todd, C.W.1    Colley, D.G.2
  • 85
    • 0345865108 scopus 로고    scopus 로고
    • The influence of sampling effort and the performance of the Kato-Katz technique in diagnosing Schistosoma mansoni and hookworm coinfections in rural Cote d'Ivoire
    • Booth M, Vounatsou P, N'goran EK, Tanner M, Utzinger J. The influence of sampling effort and the performance of the Kato-Katz technique in diagnosing Schistosoma mansoni and hookworm coinfections in rural Cote d'Ivoire. Parasitology 127, 525-531 (2003).
    • (2003) Parasitology , vol.127 , pp. 525-531
    • Booth, M.1    Vounatsou, P.2    N'goran, E.K.3    Tanner, M.4    Utzinger, J.5
  • 86
    • 0029961305 scopus 로고    scopus 로고
    • Hemoquant determination of hookworm-related blood loss and its role in iron deficiency in African children
    • Stoltzfus RJ, Albonico M, Chwaya HM et al. Hemoquant determination of hookworm-related blood loss and its role in iron deficiency in African children. Am. J. Trop. Med. Hyg. 55(4), 399-404 (1996). Provides data on the relationships among hookworm infection, intestinal blood loss, and iron status among school children.
    • (1996) Am. J. Trop. Med. Hyg. , vol.55 , Issue.4 , pp. 399-404
    • Stoltzfus, R.J.1    Albonico, M.2    Chwaya, H.M.3
  • 87
    • 0026569490 scopus 로고
    • The epidemiology and population biology of Necator americanus infection in a rural community in Zimbabwe
    • Bradley M, Chandiwana SK, Bundy DAP, Medley GF. The epidemiology and population biology of Necator americanus infection in a rural community in Zimbabwe. Trans. R. Soc. Trop. Med Hyg. 86, 73-76 (1992). causes of hookworm anemia. Am. J. Trop. Med. Hyg. 15, 1031-110 (1966).
    • (1992) Trans. R. Soc. Trop. Med Hyg. , vol.86 , pp. 73-76
    • Bradley, M.1    Chandiwana, S.K.2    Bundy, D.A.P.3    Medley, G.F.4
  • 88
    • 0000743028 scopus 로고
    • Bradley M, Chandiwana SK, Bundy DAP, Medley GF. The epidemiology and population biology of Necator americanus infection in a rural community in Zimbabwe. Trans. R. Soc. Trop. Med Hyg. 86, 73-76 (1992). causes of hookworm anemia. Am. J. Trop. Med. Hyg. 15, 1031-110 (1966).
    • (1966) Am. J. Trop. Med. Hyg. , vol.15 , pp. 1031-1110
  • 89
    • 10444279377 scopus 로고    scopus 로고
    • The economics of worm control
    • Holland CV, Kennedy MW (Eds). Kluwer Academic Publishers, Boston, USA
    • Guyatt HL. The economics of worm control. In: The Geohelminths. Ascaris, Trichuris and Hookworm. Holland CV, Kennedy MW (Eds). Kluwer Academic Publishers, Boston, USA, 75-87 (2001). Summarizes and evaluates the costs incurred in implementing school-based delivery of anthelmintics.
    • (2001) The Geohelminths. Ascaris, Trichuris and Hookworm , pp. 75-87
    • Guyatt, H.L.1
  • 90
    • 0142026120 scopus 로고    scopus 로고
    • Methodological issues and new developments in the economic evaluation of vaccines
    • Beutels P, van Doorslaer E, van Damme, Hall J. Methodological issues and new developments in the economic evaluation of vaccines. Expert Rev. Vaccines 2, 89-100 (2003).
    • (2003) Expert Rev. Vaccines , vol.2 , pp. 89-100
    • Beutels, P.1    Van Doorslaer, E.2    Van Damme3    Hall, J.4
  • 91
    • 0029000468 scopus 로고
    • Desirable characteristics of a schistosomiasis vaccine: Some implications of a cost-effectiveness analysis
    • Guyatt HL, Evans D. Desirable characteristics of a schistosomiasis vaccine: some implications of a cost-effectiveness analysis. Acta Tropica 59, 197-209 (1995). Investigates the relative cost effectiveness of a vaccine for schistosomiasis relative to chemotherapy.
    • (1995) Acta Tropica , vol.59 , pp. 197-209
    • Guyatt, H.L.1    Evans, D.2
  • 92
    • 0030801912 scopus 로고    scopus 로고
    • Human schistosomiasis: Potential long term consequences of vaccination programs
    • Chan MS, Woolhouse MEJ, Bundy DAP. Human schistosomiasis: potential long term consequences of vaccination programs. Vaccine 15, 1545-1550 (1997).
    • (1997) Vaccine , vol.15 , pp. 1545-1550
    • Chan, M.S.1    Woolhouse, M.E.J.2    Bundy, D.A.P.3
  • 93
    • 0031836574 scopus 로고    scopus 로고
    • Comparison of the cost effectiveness of vaccines and insecticide impregnation of mosquito nets for the prevention of malaria
    • Graves PM. Comparison of the cost effectiveness of vaccines and insecticide impregnation of mosquito nets for the prevention of malaria. Ann. Trop. Med. Parasitol. 92, 399-410 (1998).
    • (1998) Ann. Trop. Med. Parasitol. , vol.92 , pp. 399-410
    • Graves, P.M.1
  • 94
    • 0034141644 scopus 로고    scopus 로고
    • Schistosomiasis vaccines: A devil's advocate view
    • Gryseels B. Schistosomiasis vaccines: a devil's advocate view. Parasitol. Today 16, 46-48 (2000). Adopting a position of devil's advocate, raises some scientific, ethical and practical concerns about develop a schistosomal vaccine.
    • (2000) Parasitol. Today , vol.16 , pp. 46-48
    • Gryseels, B.1
  • 95
    • 0345471386 scopus 로고    scopus 로고
    • Some important issues in the planning of Phase III HIV vaccine efficacy trials
    • Boily MC, Masse BR, Desai K, Alary M, Anderson RM. Some important issues in the planning of Phase III HIV vaccine efficacy trials. Vaccine 17, 989-1004 (1999).
    • (1999) Vaccine , vol.17 , pp. 989-1004
    • Boily, M.C.1    Masse, B.R.2    Desai, K.3    Alary, M.4    Anderson, R.M.5
  • 96
    • 0036106141 scopus 로고    scopus 로고
    • Mathematical modeling of Schistosomiasis japonica: Comparison of control strategies in the People's Republic of China
    • Williams GM, Sleigh AC, Li Y et al. Mathematical modeling of Schistosomiasis japonica: comparison of control strategies in the People's Republic of China. Acta Trop. 82, 253-262 (2002).
    • (2002) Acta Trop. , vol.82 , pp. 253-262
    • Williams, G.M.1    Sleigh, A.C.2    Li, Y.3
  • 97
    • 0027964626 scopus 로고
    • The development and validation of an age-stratified model for the evaluation of disease control strategies for intestinal helminths
    • Chan MS, Guyatt HL, Bundy DAP, Medley GF. The development and validation of an age-stratified model for the evaluation of disease control strategies for intestinal helminths. Parasitology 109, 389-396 (1994).
    • (1994) Parasitology , vol.109 , pp. 389-396
    • Chan, M.S.1    Guyatt, H.L.2    Bundy, D.A.P.3    Medley, G.F.4
  • 101
    • 0019362251 scopus 로고
    • Introduction to sample size determination and power analysis for clinical trials
    • Lachin JM. Introduction to sample size determination and power analysis for clinical trials. Control. Clin. Trials 2, 93-113 (1981).
    • (1981) Control. Clin. Trials , vol.2 , pp. 93-113
    • Lachin, J.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.