-
7
-
-
85030814893
-
-
U.S. Patent 5468767, 1995
-
Cipollina, J. A., Mattson, R. J., Sloan, C. P. U.S. Patent 5468767, 1995
-
-
-
Cipollina, J.A.1
Mattson, R.J.2
Sloan, C.P.3
-
8
-
-
4444353338
-
-
T. Heinrich, H. Böttcher, R. Gericke, G.D. Bartoszyk, S. Anzali, C.A. Seyfried, H.E. Greiner, and C. van Amsterdam J. Med. Chem. 47 2004 4684 4692
-
(2004)
J. Med. Chem.
, vol.47
, pp. 4684-4692
-
-
Heinrich, T.1
Böttcher, H.2
Gericke, R.3
Bartoszyk, G.D.4
Anzali, S.5
Seyfried, C.A.6
Greiner, H.E.7
Van Amsterdam, C.8
-
9
-
-
85030812412
-
-
U.S. Patent 5846982, 1998
-
Audia, J. E., Koch, D. J., Mabry, T. E., Rocco, V., P., Xu, Y-C. U.S. Patent 5846982, 1998
-
-
-
Audia, J.E.1
Koch, D.J.2
Mabry, T.E.3
Rocco, V.4
Xu, Y.-C.5
-
10
-
-
0035939309
-
-
K.L. Meagher, R.E. Mewshaw, D.A. Evrard, P. Zhou, D.L. Smith, R. Scerni, T. Spangler, S. Abulhawa, X. Shi, L.E. Schechter, and T.H. Andree Bioorg. Med. Chem. Lett. 11 2001 1885 1888
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 1885-1888
-
-
Meagher, K.L.1
Mewshaw, R.E.2
Evrard, D.A.3
Zhou, P.4
Smith, D.L.5
Scerni, R.6
Spangler, T.7
Abulhawa, S.8
Shi, X.9
Schechter, L.E.10
Andree, T.H.11
-
11
-
-
3142579793
-
-
R.E. Mewshaw, D. Zhou, P. Zhou, X. Shi, G. Hornby, T. Spangler, R. Scerni, D. Smith, L.E. Schechter, and T.H. Andree J. Med. Chem. 47 2004 3823 3842
-
(2004)
J. Med. Chem.
, vol.47
, pp. 3823-3842
-
-
Mewshaw, R.E.1
Zhou, D.2
Zhou, P.3
Shi, X.4
Hornby, G.5
Spangler, T.6
Scerni, R.7
Smith, D.8
Schechter, L.E.9
Andree, T.H.10
-
15
-
-
2142819957
-
-
M. Dukat, C. Smith, K. Herrick-Davis, M. Teitler, and R.A. Glennon Bioorg. Med. Chem. 12 2004 2545 2552
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 2545-2552
-
-
Dukat, M.1
Smith, C.2
Herrick-Davis, K.3
Teitler, M.4
Glennon, R.A.5
-
19
-
-
85030812895
-
-
note
-
Percent inhibition at both norepinephrine and dopamine transporters was found to be <50% at a concentration of 1 μM for all active (<1000 nM) SERT compounds listed in Table 1. The most potent compounds exhibited the best selectivity; for example, 2J showed 14% inhibition at the norepinephrine transporter and 4% at the dopamine transporter at 1 μM
-
-
-
-
20
-
-
0026462892
-
-
J.E. Macor, J. Blake, C.B. Fox, C. Johnson, B.K. Koe, L.A. Lebel, J.M. Morrone, K. Ryan, A.W. Schmidt, D.W. Schulz, and S.H. Zorn J. Med. Chem. 35 1992 4503 4505
-
(1992)
J. Med. Chem.
, vol.35
, pp. 4503-4505
-
-
MacOr, J.E.1
Blake, J.2
Fox, C.B.3
Johnson, C.4
Koe, B.K.5
Lebel, L.A.6
Morrone, J.M.7
Ryan, K.8
Schmidt, A.W.9
Schulz, D.W.10
Zorn, S.H.11
-
21
-
-
0026754567
-
-
J.E. Macor, C.B. Fox, C. Johnson, B.K. Koe, L.A. Lebel, and S.H. Zorn J. Med. Chem. 35 1992 3625 3632
-
(1992)
J. Med. Chem.
, vol.35
, pp. 3625-3632
-
-
MacOr, J.E.1
Fox, C.B.2
Johnson, C.3
Koe, B.K.4
Lebel, L.A.5
Zorn, S.H.6
-
22
-
-
0034704821
-
-
L. Matzen, C. Amsterdam, W. Rautenberg, H.E. Greiner, J. Harting, C.A. Seyfried, and H. Bottcher J. Med. Chem. 43 2000 1149 1157
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1149-1157
-
-
Matzen, L.1
Amsterdam, C.2
Rautenberg, W.3
Greiner, H.E.4
Harting, J.5
Seyfried, C.A.6
Bottcher, H.7
-
23
-
-
3843139591
-
-
K.M. Boy, M. Dee, J. Yevich, J. Torrente, Q. Gao, L. Iben, A. Stark, and R.J. Mattson Bioorg. Med. Chem. Lett. 14 2004 4467 4470
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 4467-4470
-
-
Boy, K.M.1
Dee, M.2
Yevich, J.3
Torrente, J.4
Gao, Q.5
Iben, L.6
Stark, A.7
Mattson, R.J.8
-
24
-
-
12444346791
-
-
N. Toda, K. Tago, S. Marumoto, K. Takami, M. Ori, N. Yamada, K. Koyama, S. Naruto, K. Abe, R. Yamazaki, T. Hara, A. Aoyagi, Y. Abe, T. Kaneko, and H. Kogen Bioorg. Med. Chem. 11 2003 4389 4415
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 4389-4415
-
-
Toda, N.1
Tago, K.2
Marumoto, S.3
Takami, K.4
Ori, M.5
Yamada, N.6
Koyama, K.7
Naruto, S.8
Abe, K.9
Yamazaki, R.10
Hara, T.11
Aoyagi, A.12
Abe, Y.13
Kaneko, T.14
Kogen, H.15
|