Prevention of naphthalene-induced pulmonary toxicity by glutathione prodrugs: Roles for glutathione depletion in adduct formation and cell injury

Journal of Biochemical and Molecular Toxicology

Volumn 19, Issue 1, 2005, Pages 42-51

  Phimister, Andrew J ^a   Nagasawa, H T ^b   Buckpitt, A R ^a   Plopper, C G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cysteine Glutathione Mixed Disulfide; Glutathione Prodrugs; Naphthalene; Pulmonary Toxicology

Indexed keywords

CYSTEINE GLUTATHIONE MIXED DISULFIDE; GLUTATHIONE DERIVATIVE; GLUTATHIONE DISULFIDE; GLUTATHIONE ETHYL ESTER; NAPHTHALENE; NAPHTHALENE PROTEIN ADDUCT; PRODRUG; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEATH; CLARA CELL; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COVALENT BOND; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ASSAY; EXPLANT; IN VITRO STUDY; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN BINDING; TOXICOKINETICS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROCHEMISTRY; EPITHELIUM; GLUTATHIONE; LUNG; MALE; MICE; NAPHTHALENES; PRODRUGS; SOLUBILITY; WATER;

EID: 14644426650     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.20052     Document Type: Article

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