-
1
-
-
0642364454
-
Heat-induced liver injury in old rats is associated with exaggerated oxidative stress and altered transcription factor activation
-
Zhang HJ, Xu L, Drake VJ, Xie L, Oberley LW, Kregel KC. Heat-induced liver injury in old rats is associated with exaggerated oxidative stress and altered transcription factor activation. FASEB J. 2003;17: 2293-2295.
-
(2003)
FASEB J
, vol.17
, pp. 2293-2295
-
-
Zhang, H.J.1
Xu, L.2
Drake, V.J.3
Xie, L.4
Oberley, L.W.5
Kregel, K.C.6
-
2
-
-
0038476368
-
Effect of age and hypoxia/reoxygenation on mRNA expression of antioxidative enzymes in rat liver and kidneys
-
Martin R, Fitzl G, Mozet C, Martin H, Welt K, Wieland E. Effect of age and hypoxia/reoxygenation on mRNA expression of antioxidative enzymes in rat liver and kidneys. Exp Gerontol 2002;37:1481-1487.
-
(2002)
Exp Gerontol
, vol.37
, pp. 1481-1487
-
-
Martin, R.1
Fitzl, G.2
Mozet, C.3
Martin, H.4
Welt, K.5
Wieland, E.6
-
3
-
-
0030039483
-
Alterations in autonomic adjustments to acute hypoxia in conscious rats with aging
-
Kregel KC. Alterations in autonomic adjustments to acute hypoxia in conscious rats with aging. J Appl Physiol. 1996;80:540-546.
-
(1996)
J Appl Physiol
, vol.80
, pp. 540-546
-
-
Kregel, K.C.1
-
4
-
-
0033035039
-
Physiological changes in respiratory function associated with ageing
-
Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J. 1999;13:197-205.
-
(1999)
Eur Respir J
, vol.13
, pp. 197-205
-
-
Janssens, J.P.1
Pache, J.C.2
Nicod, L.P.3
-
5
-
-
0037218826
-
The biology of aging
-
Troen BR. The biology of aging. Mt Sinai J Med. 2003;70:3-22.
-
(2003)
Mt Sinai J Med
, vol.70
, pp. 3-22
-
-
Troen, B.R.1
-
6
-
-
0031732240
-
Ageing affects anoxia/ reoxygenation injury in rat hepatocytes
-
Gasbarrini A, Simoncini M, Di Campli C, et al. Ageing affects anoxia/ reoxygenation injury in rat hepatocytes. Scand J Gastroenterol. 1998;33:1107-1112.
-
(1998)
Scand J Gastroenterol
, vol.33
, pp. 1107-1112
-
-
Gasbarrini, A.1
Simoncini, M.2
Di Campli, C.3
-
7
-
-
0042924108
-
Blunted cardiac autonomic responsiveness to hypoxemic stress in healthy older adults
-
Lucy SD, Kowalchuk JM, Hughson RL, Paterson DH, Cunningham DA. Blunted cardiac autonomic responsiveness to hypoxemic stress in healthy older adults. Can J Appl Physiol. 2003;28:518-535.
-
(2003)
Can J Appl Physiol
, vol.28
, pp. 518-535
-
-
Lucy, S.D.1
Kowalchuk, J.M.2
Hughson, R.L.3
Paterson, D.H.4
Cunningham, D.A.5
-
8
-
-
0033774930
-
Tolerance to ischemia and hypoxia is reduced in aged human myocardium
-
Mariani J, Ou R, Bailey M, et al. Tolerance to ischemia and hypoxia is reduced in aged human myocardium. J Thorac Cardiovasc Surg. 2000;120:660-667.
-
(2000)
J Thorac Cardiovasc Surg
, vol.120
, pp. 660-667
-
-
Mariani, J.1
Ou, R.2
Bailey, M.3
-
9
-
-
0023551385
-
Heat tolerance, thermoregulation and ageing
-
Kenney WL, Hodgson JL. Heat tolerance, thermoregulation and ageing. Sports Med. 1987;4:446-456.
-
(1987)
Sports Med
, vol.4
, pp. 446-456
-
-
Kenney, W.L.1
Hodgson, J.L.2
-
11
-
-
0035542970
-
AMP-activated protein kinase: The energy charge hypothesis revisited
-
Hardie DG, Hawley SA. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays. 2001;23:1112-1119.
-
(2001)
Bioessays
, vol.23
, pp. 1112-1119
-
-
Hardie, D.G.1
Hawley, S.A.2
-
12
-
-
0038199737
-
Management of cellular energy by the AMP-activated protein kinase system
-
Hardie DG, Scott JW, Pan DA, Hudson ER. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett. 2003;546:113-120.
-
(2003)
FEBS Lett
, vol.546
, pp. 113-120
-
-
Hardie, D.G.1
Scott, J.W.2
Pan, D.A.3
Hudson, E.R.4
-
13
-
-
0042847434
-
AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability
-
Hong YH, Varanasi US, Yang W, Leff T. AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability. J Biol Chem. 2003;278:27495-27501.
-
(2003)
J Biol Chem
, vol.278
, pp. 27495-27501
-
-
Hong, Y.H.1
Varanasi, U.S.2
Yang, W.3
Leff, T.4
-
14
-
-
0141905919
-
Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis
-
Rutter GA, Da Silva Xavier G, Leclerc I. Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis. Biochem J. 2003;375:1-16.
-
(2003)
BiochemJ
, vol.375
, pp. 1-16
-
-
Rutter, G.A.1
Da Silva Xavier, G.2
Leclerc, I.3
-
15
-
-
0036545345
-
Role of AMP-activated protein kinase in the regulation of gene transcription
-
Leclerc I, Viollet B, da Silva Xavier G, Kahn A, Rutter GA. Role of AMP-activated protein kinase in the regulation of gene transcription. Biochem Soc Trans. 2002;30:307-311.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 307-311
-
-
Leclerc, I.1
Viollet, B.2
Da Silva Xavier, G.3
Kahn, A.4
Rutter, G.A.5
-
16
-
-
1242340445
-
Differential regulation of phosphatidylinositol 3-kinase/Akt, mitogen-activated protein kinase, and AMP-activated protein kinase pathways during menadione-induced oxidative stress in the kidney of young and old rats
-
Jin Q, Jhun BS, Lee SH, et al. Differential regulation of phosphatidylinositol 3-kinase/Akt, mitogen-activated protein kinase, and AMP-activated protein kinase pathways during menadione-induced oxidative stress in the kidney of young and old rats. Biochem Biophys Res Commun. 2004;315:555-561.
-
(2004)
Biochem Biophys Res Commun
, vol.315
, pp. 555-561
-
-
Jin, Q.1
Jhun, B.S.2
Lee, S.H.3
-
17
-
-
0033870805
-
Sip2p and its partner snf1p kinase affect aging in S. cerevisiae
-
Ashrafi K, Lin SS, Manchester JK, Gordon JI. Sip2p and its partner snf1p kinase affect aging in S. cerevisiae. Genes Dev. 2000;14:1872-1885.
-
(2000)
Genes Dev
, vol.14
, pp. 1872-1885
-
-
Ashrafi, K.1
Lin, S.S.2
Manchester, J.K.3
Gordon, J.I.4
-
18
-
-
0036238675
-
AMP-activated kinase regulates cytoplasmic HuR
-
Wang W, Fan J, Yang X, et al. AMP-activated kinase regulates cytoplasmic HuR. Mol Cell Biol. 2002;22:3425-3436.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3425-3436
-
-
Wang, W.1
Fan, J.2
Yang, X.3
-
20
-
-
0036289911
-
Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations
-
Halseth AE, Ensor NJ, White TA, Ross SA, Gulve EA. Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations. Biochem Biophys Res Commun. 2002;294:798-805.
-
(2002)
Biochem Biophys Res Commun
, vol.294
, pp. 798-805
-
-
Halseth, A.E.1
Ensor, N.J.2
White, T.A.3
Ross, S.A.4
Gulve, E.A.5
-
21
-
-
0028406897
-
Role of the AMP-activated protein kinase in the cellular stress response
-
Corton JM, Gillespie JG, Hardie DG. Role of the AMP-activated protein kinase in the cellular stress response. Curr Biol. 1994;4:315-324.
-
(1994)
Curr Biol
, vol.4
, pp. 315-324
-
-
Corton, J.M.1
Gillespie, J.G.2
Hardie, D.G.3
-
22
-
-
0037323888
-
AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart
-
Hopkins TA, Dyck JR, Lopaschuk GD. AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart. Biochem Soc Trans. 2003;31:207-212.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 207-212
-
-
Hopkins, T.A.1
Dyck, J.R.2
Lopaschuk, G.D.3
-
23
-
-
0032213768
-
AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release
-
Salt IP, Johnson G, Ashcroft SJ, Hardie DG. AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release. Biochem J. 1998;335(Pt 3): 533-539.
-
(1998)
Biochem J
, vol.335
, Issue.PART 3
, pp. 533-539
-
-
Salt, I.P.1
Johnson, G.2
Ashcroft, S.J.3
Hardie, D.G.4
-
24
-
-
0035189594
-
Adenosine monophosphate-activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat
-
Peralta C, Bartrons R, Serafin A, et al. Adenosine monophosphate- activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat. Hepatology. 2001;34:1164-1173.
-
(2001)
Hepatology
, vol.34
, pp. 1164-1173
-
-
Peralta, C.1
Bartrons, R.2
Serafin, A.3
-
25
-
-
0024839973
-
Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay
-
Davies SP, Carling D, Hardie DG. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur J Biochem. 1989;186:123-128.
-
(1989)
Eur J Biochem
, vol.186
, pp. 123-128
-
-
Davies, S.P.1
Carling, D.2
Hardie, D.G.3
-
26
-
-
0038035142
-
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function
-
Wang W, Yang X, Lopez de Silanes I, Carling D, Gorospe M. Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. J Biol Chem. 2003;278:27016-27023.
-
(2003)
J Biol Chem
, vol.278
, pp. 27016-27023
-
-
Wang, W.1
Yang, X.2
De Lopez Silanes, I.3
Carling, D.4
Gorospe, M.5
-
27
-
-
0029978799
-
Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
-
Winder WW, Hardie DG. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol. 1996;270:E299-304.
-
(1996)
Am J Physiol
, vol.270
-
-
Winder, W.W.1
Hardie, D.G.2
-
28
-
-
0020792125
-
Energy metabolism in the liver of young and old rats during starvation
-
Kosenko EA, Kaminskii Iu G. [Energy metabolism in the liver of young and old rats during starvation]. Ukr Biokhim Zh. 1983;55:425-430.
-
(1983)
Ukr Biokhim Zh
, vol.55
, pp. 425-430
-
-
Kosenko, E.A.1
Kaminskii Iu, G.2
-
29
-
-
0034567756
-
The effects of galactosamine on UTP levels in the livers of young, adult and old rats
-
Kmiec Z, Smolenski RT, Zych M, Mysliwski A. The effects of galactosamine on UTP levels in the livers of young, adult and old rats. Acta Biochim Pol. 2000;47:349-353.
-
(2000)
Acta Biochim Pol
, vol.47
, pp. 349-353
-
-
Kmiec, Z.1
Smolenski, R.T.2
Zych, M.3
Mysliwski, A.4
-
30
-
-
0035120774
-
Pseudocapillarization and associated energy limitation in the aged rat liver
-
Le Couteur DG, Cogger VC, Markus AM, et al. Pseudocapillarization and associated energy limitation in the aged rat liver. Hepatology. 2001;33:537-543.
-
(2001)
Hepatology
, vol.33
, pp. 537-543
-
-
Le Couteur, D.G.1
Cogger, V.C.2
Markus, A.M.3
-
31
-
-
0038580003
-
Effect of age and photoperiodic conditions on metabolism and oxidative stress related markers at different circadian stages in rat liver and kidney
-
Martin C, Dutertre-Catella H, Radionoff M, et al. Effect of age and photoperiodic conditions on metabolism and oxidative stress related markers at different circadian stages in rat liver and kidney. Life Sci. 2003;73:327-335.
-
(2003)
Life Sci
, vol.73
, pp. 327-335
-
-
Martin, C.1
Dutertre-Catella, H.2
Radionoff, M.3
-
32
-
-
0019971866
-
Response of adenine nucleotide metabolism in the aged rat liver to fasting and succinate injections
-
Kaminskii Iu G, Kosenko EA, Kondrashova MN. [Response of adenine nucleotide metabolism in the aged rat liver to fasting and succinate injections]. Biokhimiia. 1982;47:654-659.
-
(1982)
Biokhimiia
, vol.47
, pp. 654-659
-
-
Kaminskii Iu, G.1
Kosenko, E.A.2
Kondrashova, M.N.3
-
33
-
-
0038644946
-
Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing
-
Lin SS, Manchester JK, Gordon JI. Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing. J Biol Chem. 2003;278:13390-13397.
-
(2003)
J Biol Chem
, vol.278
, pp. 13390-13397
-
-
Lin, S.S.1
Manchester, J.K.2
Gordon, J.I.3
-
34
-
-
0036535031
-
Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells
-
Fryer LG, Foufelle F, Barnes K, Baldwin SA, Woods A, Carling D. Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells. Biochem J. 2002;363:167-174.
-
(2002)
BiochemJ
, vol.363
, pp. 167-174
-
-
Fryer, L.G.1
Foufelle, F.2
Barnes, K.3
Baldwin, S.A.4
Woods, A.5
Carling, D.6
-
35
-
-
0032704115
-
Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
-
Holmes BF, Kurth-Kraczek EJ, Winder WW. Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J Appl Physiol. 1999;87:1990-1995.
-
(1999)
J Appl Physiol
, vol.87
, pp. 1990-1995
-
-
Holmes, B.F.1
Kurth-Kraczek, E.J.2
Winder, W.W.3
-
36
-
-
0036307179
-
Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome
-
Buhl ES, Jessen N, Fold R, et al. Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome. Diabetes. 2002;51:2199-2206.
-
(2002)
Diabetes
, vol.51
, pp. 2199-2206
-
-
Buhl, E.S.1
Jessen, N.2
Fold, R.3
-
37
-
-
0033815967
-
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
-
Woods A, Azzout-Marniche D, Foretz M, et al. Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol. 2000;20:6704-6711.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6704-6711
-
-
Woods, A.1
Azzout-Marniche, D.2
Foretz, M.3
-
38
-
-
0038584871
-
Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
-
da Silva Xavier G, Leclerc I, Varadi A, Tsuboi T, Moule SK, Rutter GA. Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression. Biochem J. 2003;371:761-774.
-
(2003)
Biochem J
, vol.371
, pp. 761-774
-
-
Silva Xavier, G.1
Leclerc, I.2
Varadi, A.3
Tsuboi, T.4
Moule, S.K.5
Rutter, G.A.6
-
39
-
-
0037189947
-
Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells
-
Meisse D, Van de Casteele M, Beauloye C, et al. Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells. FEBS Lett. 2002;526:38-42.
-
(2002)
FEBS Lett
, vol.526
, pp. 38-42
-
-
Meisse, D.1
Van De Casteele, M.2
Beauloye, C.3
-
40
-
-
0038363852
-
AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase
-
Kefas BA, Cai Y, Ling Z, et al. AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase. J Mol Endocrinol. 2003;30:151-161.
-
(2003)
J Mol Endocrinol
, vol.30
, pp. 151-161
-
-
Kefas, B.A.1
Cai, Y.2
Ling, Z.3
-
41
-
-
0037301056
-
AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase
-
Kefas BA, Heimberg H, Vaulont S, et al. AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase. Diabetologia. 2003;46:250-254.
-
(2003)
Diabetologia
, vol.46
, pp. 250-254
-
-
Kefas, B.A.1
Heimberg, H.2
Vaulont, S.3
-
42
-
-
0037461107
-
Constitutively active adenosine monophosphate-activated protein kinase regulates voltage-gated sodium channels in ventricular myocytes
-
Light PE, Wallace CHR, Dyck JRB. Constitutively active adenosine monophosphate-activated protein kinase regulates voltage-gated sodium channels in ventricular myocytes. Circulation. 2003;107:1962-1965.
-
(2003)
Circulation
, vol.107
, pp. 1962-1965
-
-
Light, P.E.1
Wallace, C.H.R.2
Dyck, J.R.B.3
-
43
-
-
0036167225
-
Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy
-
Arad M, Benson DW, Perez-Atayde AR, et al. Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. J Clin Invest. 2002;109:357-362.
-
(2002)
J Clin Invest
, vol.109
, pp. 357-362
-
-
Arad, M.1
Benson, D.W.2
Perez-Atayde, A.R.3
-
44
-
-
0032748767
-
The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice
-
Frenkel-Denkberg G, Gershon D, Levy AP. The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice. FEBS Lett. 1999;462:341-344.
-
(1999)
FEBS Lett
, vol.462
, pp. 341-344
-
-
Frenkel-Denkberg, G.1
Gershon, D.2
Levy, A.P.3
-
45
-
-
0141960109
-
AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
-
Lee M, Hwang JT, Lee HJ, et al. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells. J Biol Chem. 2003;278:39653-39661.
-
(2003)
J Biol Chem
, vol.278
, pp. 39653-39661
-
-
Lee, M.1
Hwang, J.T.2
Lee, H.J.3
-
46
-
-
0024242624
-
Changes in the modulations of kinetics and allosteric properties of muscle phosphofructokinase of young and old rats
-
Trigun SK, Singh SN. Changes in the modulations of kinetics and allosteric properties of muscle phosphofructokinase of young and old rats. Arch Gerontol Geriatr. 1988;7:239-247.
-
(1988)
Arch Gerontol Geriatr
, vol.7
, pp. 239-247
-
-
Trigun, S.K.1
Singh, S.N.2
|