Discreet mutations from c-Rel to v-Rel alter κB DNA recognition, IκBα binding, and dimerization: Implications for v-Rel oncogenicity

Oncogene

Volumn 23, Issue 6, 2004, Pages 1229-1238

  Phelps, Christopher B ^a   Ghosh, Gourisankar ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MC 0359 ^*  (United States)

Author keywords

DNA binding; Fluorescence anisotropy; I B ; NF B; v Rel

Indexed keywords

CELL PROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ONCOPROTEIN; TRANSCRIPTION FACTOR REL; DNA; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PRIMER DNA; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CARCINOGENICITY; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; FLUORESCENCE ANALYSIS; GENE EXPRESSION; GENE MUTATION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION; ANIMAL; CHEMISTRY; CHICKEN; DRUG ANTAGONISM; ESCHERICHIA COLI; GENETICS; HUMAN; METABOLISM; MOLECULAR CLONING; MUTATION; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS;

AVES; UNIDENTIFIED RETROVIRUS;

ANIMALS; BASE SEQUENCE; CHICKENS; CLONING, MOLECULAR; DIMERIZATION; DNA; DNA PRIMERS; ESCHERICHIA COLI; HUMANS; I-KAPPA B PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION; NF-KAPPA B; ONCOGENE PROTEINS V-REL; PROTO-ONCOGENE PROTEINS C-REL; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 1442327513     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207242     Document Type: Article

References (63)

1. Baeuerle PA and Baltimore D. (1996). Cell, 87, 13-20.
2. Baeuerle PA and Henkel T. (1994). Annu. Rev. Immunol., 12, 141-179.
3. Baldwin Jr AS. (1996). Annu. Rev. Immunol., 14, 649-683.
4. Barroga CF, Stevenson JK, Schwarz EM and Verma IM. (1995). Proc. Natl. Acad. Sci. USA, 92, 7637-7641.
5. Berkowitz B, Huang DB, Chen-Park FE, Sigler PB and Ghosh G. (2002). J. Biol. Chem., 277, 24694-24700.
6. Bharti AC and Aggarwal BB. (2002). Biochem. Pharmacol., 64, 883-888.
7. Capobianco AJ, Chang D, Mosialos G and Gilmore TD. (1992). J. Virol., 66, 3758-3767.
8. Capobianco AJ, Simmons DL and Gilmore TD. (1990). Oncogene, 5, 257-265.
9. Carrasco D, Rizzo CA, Dorfman K and Bravo R. (1996). EMBO J., 15, 3640-3650.
10. Chen C, Agnes F and Gelinas C. (1999a). Mol. Cell. Biol., 19, 307-316.
11. Chen C, Edelstein LC and Gelinas C. (2000a). Mol. Cell. Biol., 20, 2687-2695.
12. Chen FE and Ghosh G. (1999). Oncogene, 18, 6845-6852.
13. Chen FE, Huang DB, Chen YQ and Ghosh G. (1998a). Nature, 391, 410-413.
14. Chen FE, Kempiak S, Huang DB, Phelps C and Ghosh G. (1999b). Protein Eng., 12, 423-428.
15. Chen YQ, Ghosh S and Ghosh G. (1998b). Nat. Struct. Biol., 5, 67-73.
16. Chen YQ, Sengchanthalangsy LL, Hackett A and Ghosh G. (2000b). Struc. Fold Des., 8, 419-428.
17. Cheng Q, Cant CA, Moll T, Hofer-Warbinek R, Wagner E, Birnstiel ML, Bach FH and de Martin R. (1994). J. Biol. Chem., 269, 13551-13557.
18. Cramer P, Larson CJ, Verdine GL and Muller CW. (1997). EMBO J., 16, 7078-7090.
19. Davis N, Bargmann W, Lim MY and Bose Jr H. (1990). J. Virol., 64, 584-591.
20. Duyao MP, Buckler AJ and Sonenshein GE. (1990). Proc. Natl. Acad. Sci. USA, 87, 4727-4731.
21. Epinat JC, Dvorin EL and Gilmore TD. (2000a). Oncogene, 19, 3131-3137.
22. Epinat JC, Kazandjian D, Harkness DD, Petros S, Dave J, White DW and Gilmore TD. (2000b). Oncogene, 19, 599-607.
23. Ghosh G, van Duyne G, Ghosh S and Sigler PB. (1995). Nature, 373, 303-310.
24. Ghosh S, May MJ and Kopp EB. (1998). Annu. Rev. Immunol., 16, 225-260.
25. Gilmore TD. (1999). Oncogene, 18, 6925-6937.
26. Gilmore TD and Temin HM. (1986). Cell, 44, 791-800.
27. Grumont RJ and Gerondakis S. (2000). J. Exp. Med., 191, 1281-1292.
28. Hannink M and Temin HM. (1989). Mol. Cell. Biol., 9, 4323-4336.
29. Hannink M and Temin HM. (1990). Oncogene, 5, 1843-1850.
30. Heckman CA, Mehew JW and Boxer LM. (2002). Oncogene, 21, 3898-3908.
31. Hrdlickova R, Nehyba J and Bose Jr HR. (2001). Mol. Cell. Biol., 21, 6369-6386.
32. Hrdlickova R, Nehyba J, Roy A, Humphries EH and Bose Jr HR. (1995). J. Virol., 69, 403-413.
33. Huang DB, Chen YQ, Ruetsche M, Phelps CB and Ghosh G. (2001). Struct. (Camb), 9, 669-678.
34. Huxford T, Huang DB, Malek S and Ghosh G. (1998). Cell, 95, 759-770.
35. Huxford T, Malek S and Ghosh G. (2000). J. Biol. Chem., 275, 32800-32806.
36. Jacobs MD and Harrison SC. (1998). Cell, 95, 749-758.
37. Kralova J, Liss AS, Bargmann W and Bose Jr HR. (1998). Mol. Cell. Biol., 18, 2997-3009.
38. Kumar S, Rabson AB and Gelinas C. (1992). Mol. Cell. Biol., 12, 3094-3106.
39. Li Q and Verma IM. (2002). Nat. Rev. Immunol., 2, 725-734.
40. Liss AS and Bose Jr HR. (2002). J. Virol., 76, 4928-4939.
41. Malek S, Chen Y, Huxford T and Ghosh G. (2001). J. Biol. Chem., 276, 45225-45235.
42. Malek S, Huxford T and Ghosh G. (1998). J. Biol. Chem., 273, 25427-25435.
43. McElhinny JA, Trushin SA, Bren GD, Chester N and Paya CV. (1996). Mol. Cell. Biol., 16, 899-906.
44. Morrison LE, Boehmelt G and Enrietto PJ. (1992). Oncogene, 7, 1137-1147.
45. Muller CW, Rey FA, Sodeoka M, Verdine GL and Harrison SC. (1995). Nature, 373, 311-317.
46. Nehyba J, Hrdlickova R and Bose Jr HR. (1997). Oncogene, 14, 2881-2897.
47. Perkins ND. (1997). Int. J. Biochem Cell Biol., 29, 1433-1448.
48. Petrenko O, Ischenko I and Enrietto PJ. (1997). Oncogene, 15, 1671-1680.
49. Phelps CB, Sengchanthalangsy LL, Huxford T and Ghosh G. (2000a). J. Biol. Chem., 275, 29840-29846.
50. Phelps CB, Sengchanthalangsy LL, Malek S and Ghosh G. (2000b). J. Biol. Chem., 275, 24392-24399.
51. Rayet B, Fan Y and Gelinas C. (2003). Mol. Cell. Biol., 23, 1520-1533.
52. Sachdev S, Diehl JA, McKinsey TA, Hans A and Hannink M. (1997). Oncogene, 14, 2585-2594.
53. Sachdev S and Hannink M. (1998). Mol. Cell. Biol., 18, 5445-5456.
54. Schatzle JD, Kralova J and Bose Jr HR. (1995). J. Virol., 69, 5383-5390.
55. Siebenlist U, Franzoso G and Brown K. (1994). Annu. Rev. Cell. Biol., 10, 405-455.
56. Tam WF, Wang W and Sen R. (2001). Mol. Cell. Biol., 21, 4837-4846.
57. Theilen GH, Zeigel RF and Twiehaus MJ. (1966). J. Natl. Cancer Inst., 37, 731-743.
58. Tsukahara T, Kannagi M, Ohashi T, Kato H, Arai M, Nunez G, Iwanaga Y, Yamamoto N, Ohtani K, Nakamura M and Fujii M. (1999). J. Virol., 73, 7981-7987.
59. Walker AK and Enrietto PJ. (1996). Oncogene, 12, 2515-2525.
60. White DW and Gilmore TD. (1993). J. Virol., 67, 6876-6881.
61. Wilhelmsen KC, Eggleton K and Temin HM. (1984). J. Virol., 52, 172-182.
62. Wilhelmsen KC and Temin HM. (1984). J. Virol., 49, 521-529.
63. You M, Ku PT, Hrdlickova R and Bose Jr HR. (1997). Mol. Cell. Biol., 17, 7328-7341.