The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis

Apoptosis

Volumn 9, Issue 1, 2004, Pages 83-95

  Chu, F ^a   Borthakur, A ^a   Sun, X ^a   Barkinge, J ^a   Gudi, R ^a   Hawkins, S ^a   Prasad, Kanteti V S ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Apoptosis; BAX; BCL XL; BCL2; Caspase 3; Caspase 9; Cytochrome c; Siva; Siva 1; TNFR

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; PEPTIDE; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL STRAIN MCF 7; CELL STRAIN MDA MB 231; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RADIATION INJURY; SENSITIZATION; SIVA 1 GENE; ULTRAVIOLET RADIATION;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CELL LINE, TUMOR; COS CELLS; CYTOCHROMES C; CYTOSOL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE DELETION; GENETIC VECTORS; GLUTATHIONE TRANSFERASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS; ULTRAVIOLET RAYS;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 1442301666     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:APPT.0000012125.01799.4c     Document Type: Article

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