Inhibition of p38 Mitogen-Activated Protein Kinase Enhances Adrenergic-Stimulated Arylalkylamine N-Acetyltransferase Activity in Rat Pinealocytes

Endocrinology

Volumn 145, Issue 3, 2004, Pages 1167-1174

  Man, J R ^a   Rustaeus, S ^a   Price, D M ^a   Chik, C L ^a   Ho, A K ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b 7 26 Medical Sciences Building ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 METHOXYTRYPTAMINE; ACETYLSEROTONIN METHYLTRANSFERASE; ARALKYLAMINE ACETYLTRANSFERASE; CYCLIC AMP DERIVATIVE; MELATONIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NORADRENALIN; UNCLASSIFIED DRUG;

ADRENERGIC ACTIVITY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; HORMONE SYNTHESIS; MALE; NONHUMAN; PINEALOCYTE; PRIORITY JOURNAL; RAT;

ACETYLSEROTONIN N-METHYLTRANSFERASE; ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; BUCLADESINE; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMIDAZOLES; MALE; MELATONIN; MITOGEN-ACTIVATED PROTEIN KINASES; NOREPINEPHRINE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PINEAL GLAND; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SYMPATHOMIMETICS;

EID: 1442274662     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-1170     Document Type: Article

References (45)

1. Klein DC 1985 Photoneural regulation of the mammalian pineal gland. In: Evered D, Clark S, eds. Photoperiodism, melatonin and the pineal. Ciba Foundation Symposium. London: Pitman; vol 117:38-56
2. Klein DC, Coon SL, Roseboom PH, Weller JL, Bernard M, Gastel JA, Zatz M, Iuvone PM, Rodriguez IR, Begay V, Falcon J, Cahill GM, Cassone VM, Baler R 1997 The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland. Recent Prog Horm Res 52:307-357
3. Gastel JA, Roseboom PH, Rinaldi PA, Weller JL, Klein DC 1998 Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation. Science 279:1358-1360
4. Ganguly S, Gastel JA, Weller JL, Schwartz C, Jaffe H, Namboodiri MA, Coon SL, Hickman AB, Rollag M, Obsil T, Beauverger P, Ferry G, Boutin JA, Klein DC 2001 Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/ 14-3-3-binding switch in melatonin synthesis. Proc Natl Acad Sci USA 98: 8083-8088
5. Klein DC 1974 Circadian rhythms in indole metabolism in the rat pineal gland. In: Schmitt FO, Worden FG, eds. The neurosciences: third study program. Cambridge: MIT Press; 509-516
6. Ho AK, Hashimoto K, Chik CL 1999 3′,5′-Cyclic guanosine monophosphate activates mitogen-activated protein kinase in rat pinealoctyes. J Neurochem 73:598-604
7. Ho AK, Chik CL 2000 Adrenergic regulation of mitogen-activated protein kinase in rat pinealocytes: opposing effects of protein kinase A and protein kinase G. Endocrinology 141:4496-4502
8. Ho AK, Mackova M, Cho C, Chik CL 2003 Regulation of 90-kilodalton ribosomal S6 kinase phosphorylation in the rat pineal gland. Endocrinology 144:3344-3350
9. Seger R, Krebs EG 1995 The MAPK signaling cascade. FASEB J 9:726-735
10. Cobb MH 1999 MAP kinase pathways. Prog Biophys Mol Biol 71:479-500
11. Ray LB, Sturgill TW 1987 Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. Proc Natl Acad Sci USA 84:1502-1506
12. Boulton TG, Yancopoulos G D, Gregory JS, Slaughter C, Moomaw C, Hsu J, Cobb MH 1990 An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. Science 249:64-67
13. Jiang Y, Chen C, Li Z, Guo W, Gegner JA, Lin S, Han J 1996 Characterization of the structure and function of a new mitogen-activated protein kinase (p38β). J Biol Chem 271:17920-17926
14. Stein B, Yang MX, Young DB, Janknecht R, Hunter T, Murray BW, Barbosa MS 1997 p38-2, a novel mitogen-activated protein kinase with distinct properties. J Biol Chem 272:19509-19517
15. Pulverer BJ, Kyriakis JM, Avruch J, Nikolakaki E, Woodgett JR 1991 Phosphorylation of c-jun mediated by MAP kinases. Nature 353:670-674
16. Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B, Davis RJ 1996 Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 15:2760-2770
17. MAPK phosphorylation in rat pinealocytes. Endocrinology 141:4202-4208
18. 1A-adrenoceptors in Rat-1 cells inhibits extracellular signal-regulated kinase by activating p38 mitogen-activated protein kinase. Mol Pharmacol 54:755-760
19. MAPK cascade. J Biol Chem 274:19593-19600
20. Rolli-Derkinderen M, Machavoine F, Baraban JM, Grolleau A, Beretta L, Dy M 2003 ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1. J Biol Chem 278:18859-18867
21. Rosenberger SF, Finch JS, Gupta A, Bowden GT 1999 Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced activator protein 1 activation. J Biol Chem 274:1124-1130
22. Xing J, Kornhauser JM, Xia Z, Thiele EA, Greenberg ME 1998 Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol Cell Biol 18:1946-1955
23. Zanassi P, Paolillo M, Feliciello A, Avvedimento EV, Gallo V, Schinelli S 2001 cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons. J Biol Chem 276:11487-11495
24. Roseboom PH, Klein DC 1995 Norepinephrine stimulation of pineal cyclic AMP response element-binding protein phosphorylation: primary role of a β-adrenergic receptor/cyclic AMP mechanism. Mol Pharmacol 47:439-449
25. Buda M, Klein DC 1978 A suspension culture of pinealocytes: regulation of N-acetyltransferase activity. Endocrinology 103:1483-1493
26. Pfeffer M, Stehle JH 1998 Ontogeny of a diurnal rhythm in arylalkylamine-N-acetyltransferase mRNA in rat pineal gland. Neurosci Lett 248:163-166
27. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
28. Ho AK, Grota LJ, Brown GM 1984 Relationship between pineal N-acetyltransferase activity, pineal melatonin and serum melatonin in rats under different lighting conditions. Neuroendocrinology 39:465-470
29. Ho AK, Smith JA 1982 Effect of benserazide on the levels of pineal 5-hydroxytryptamine, melatonin synthesizing enzymes and serum melatonin. Biochem Pharmacol 31:2251-2255
30. Young PR, McLaughlin MM, Kumar S, Kassis S, Doyle ML, McNulty D, Gallagher TF, Fisher S, McDonnell PC, Carr SA, Huddleston MJ, Seibel G, Porter TG, Livi GP, Adams JL, Lee JC 1997 Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem 272: 12116-12121
31. Hazzalin CA, Cano E, Cuenda A, Barratt MJ, Cohen P, Mahadevan LC 1996 p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient. Curr Biol 6:1028-1031
32. Ho AK, Price L, Mackova M, Chik CL 2001 Potentiation of cAMP and cGMP accumulation by p38 mitogen-activated protein kinase inhibitors in rat pinealocytes. Biochem Pharmacol 62:1605-1611
33. Clark AR, Dean JL, Saklatvala J 2003 Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38. FEBS Lett 546:37-44
34. Johnson GL, Lapadat R 2002 Mitogen-activated protein kinase pathways mediated by ERK, JNK, p38 protein kinase. Science 298:1911-1912
35. Pramanik R, Qi X, Borowicz S, Choubey D, Schultz RM, Han J, Chen G 2003 p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant role of the isoforms in the p38 MAPK signal specificity. J Biol Chem 278:4831-4839
36. Reunanen N, Li S-P, Ahonen M, Foschi M, Han J, Kähäri V-M 2002 Activation of p38α MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J Biol Chem 277:32360-32368
37. Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ 2003 Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 278:18811-18816
38. Stehle JH, Foulkes NS, Molina CA, Simmoneaux V, Pévet P, Sassone-Corsi P 1993 Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland. Nature 365:314-320
39. Baler R, Covington S, Klein DC 1997 The rat arylalkylamine N-acetyltransferase gene promoter. cAMP activation via a cAMP-responsive element-CCAAT complex. J Biol Chem 272:6979-6985
40. Maronde E, Pfeffer M, Olcese J, Molina CA, Schlotter F, Dehghani F, Korf HW, Stehle JH 1999 Transcription factors in neuroendocrine regulation: rhythmic changes in pCREB and ICER levels frame melatonin synthesis. J Neurosci 19:3326-3336
41. 3H-melatonin in the cultured rat pineal gland. J Pharmacol Exp Ther 186:516-527
42. + exchange block stimulus-provoked pineal melatonin synthesis. Am J Physiol 263:E481-E488
43. Ribelayga C, Pévet P, Simonneaux V 2000 HIOMT drives the photoperiodic changes in the amplitude of the melatonin peak of the Siberian hamster. Am J Physiol 278:R1339-R1345
44. Ribelayga C, Gauer F, Calgari C, Pévet P, Simonneaux V 1999 Photoneural regulation of rat pineal hydroxyindole-O-methyltransferase (HIOMT) messenger ribonucleic acid expression: an analysis of its complex relationship with HIOMT activity. Endocrinology 140:1375-1384
45. Hayashi Y, Sanada K, Hirota T, Shimizu F, Fukada Y 2003 p38 mitogen-activated protein kinase regulates oscillation of chick pineal circadian clock. J Biol Chem 278:25166-25171