Butyrylcholinesterase antisense transfection increases apoptosis in differentiating retinal reaggregates of the chick embryo

Journal of Neurochemistry

Volumn 71, Issue 4, 1998, Pages 1413-1420

  Robitzki, Andrea ^a   Mack, Alexandra ^a   Hoppe, Ulrike ^a   Chatonnet, Arnaud ^b   Layer, Paul G ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^b CEMAGREF   (France)

Author keywords

Acetylcholinesterase; Antisense; Apoptosis; Butyryl cholinesterase; Differentiation; Photoreceptors

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE; COMPLEMENTARY DNA; DNA FRAGMENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; GENETIC TRANSFECTION; NERVE CELL DIFFERENTIATION; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DEVELOPMENT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL AGGREGATION; CELL DIFFERENTIATION; CYTOLOGY; ENZYMOLOGY; GENETICS; METABOLISM; MULTICELLULAR SPHEROID; PRENATAL DEVELOPMENT; RETINA;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

ACETYLCHOLINESTERASE; ANIMALS; APOPTOSIS; BUTYRYLCHOLINESTERASE; CELL AGGREGATION; CELL DIFFERENTIATION; CHICK EMBRYO; DNA FRAGMENTATION; DNA, ANTISENSE; PHOTORECEPTORS; RETINA; SPHEROIDS, CELLULAR; TRANSFECTION;

EID: 0031663777     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71041413.x     Document Type: Article

References (35)

1. Adler R. (1993) Determination of cellular types in the retina. Invest. Ophthalmol. Vis. Sci. 34, 1677-1682.
2. Altshuler D. and Lillien L. (1992) Control of photoreceptor development. Curr. Opin. Neurobiol. 2, 16-22.
3. Araki M. (1984) Immunocytochemical study on photoreceptor cell differentiation in the cultured retina of the chick. Dev. Biol. 103, 313-318.
4. Barthalay Y., Hipeau-Jacquotte R., De La Escalera S., Jimenez F., and Piovant M. (1990) Drosophila neurotactin mediates heterophilic cell adhesion. EMBO J. 9, 3603-3609.
5. Bok D. (1985) Retinal photoreceptor-pigment epithelium interactions Invest Ophthalmol. Vis. Sci. 26, 1659-1694.
6. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
7. Chatonnet A. and Lockridge O. (1989) Comparison of butyrylcholinesterase and acetylcholinesterase. Biochem. J. 260, 625-634.
8. Chatonnet A., Lorca T., Barakat A., and Jbilo O. (1991) Structure of rabbit butyrylcholinesterase gene deduced from genomic clones and from cDNA with introns. Cell. Mol. Neurobiol. 11, 119-130.
9. Darboux I., Barthalay Y., Piovant M., and Hipeau-Jacquotte R. (1996) The structure-functionships in drosophila neurotactin show that cholinesterasic domains may have adhesive properties. EMBO J. 15, 4835-4843.
10. Fernandes-Alnemri T., Litwack G., and Alnemri E. S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem. 269, 30761-30764.
11. Foster R. G., Garcia-Fernández J. M., Provencia I., and DeGrip W. J. (1993) Opsin localization and chromophore retinoids identified within the basal brain of the lizard Anolis carolinensis. J. Comp. Physiol. [A] 172, 33-45.
12. Gnatt A., Ginzberg D., Lieman-Hurwitz J., Zamir R., Zakut H., and Soreq H. (1991) Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes. Cell. Mol. Neurobiol. 11, 91-104.
13. Ichtchenko K., Hata Y., Nguyen T., Ullrich B., Missler M., Moomaw C., and Südhof T. C. (1995) Neuroligin 1: a splice-specific ligand for beta-neurexins. Cell 81, 435-443.
14. Inestrosa N. C., Alvarez A., Pérez C. A., Moreno R. D., Vicente M., Linker C., Casanueva O. I., Soto C., and Garrido J. (1996) Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 16, 881-891.
15. Kriegler M. P. (1990) DNA transfer, in Gene Transfer and Expression: A Laboratory Manual, Vol. 5, pp. 96-98. Stockton Press, New York.
16. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
17. Layer P. G. (1990) Cholinesterases preceding major tracts in vertebrate neurogenesis. Bioessays 12, 415-420.
18. Layer P. G. and Willbold E. (1993) Histogenesis of the avian retina in reaggregation culture: from dissociated cells to laminar neuronal networks. Int. Rev. Cytol. 146, 1-47.
19. Layer P. G. and Willbold E. (1995) Novel functions of cholinesterases in development, physiology and disease. Prog. Histochem. Cytochem. 29, 1-94.
20. Layer P. G., Alber R., and Rathjen F. G. (1988) Sequential activation of butyrylcholinesterase in rostral half somites and acetylcholinesterase in motoneurones and myotomes preceding growth of motor axons. Development 102, 387-396.
21. Layer P. G., Rothermel A., Hering H., Wolf B., DeGrip W. J., Hicks D., and Willbold E. (1997) Pigmented epithelium sustains cell proliferation and decreases expression of opsins and acetylcholinesterase in reaggregated chicken retinospheroids. Eur. J. Neurosci. 9, 1795-1803.
22. Liu X., Zou H., Slaughter C., and Wang X. (1997) DFF, a heterodimeric protein that functions downstream of caspase-3, triggers DNA fragmentation during apoptosis. Cell 89, 175-184.
23. Maniatis T., Fritsch E. F., and Sambrook J. (1982) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. Massoulié J., Pezzementi L., Bon S., Krejci E., and Valette F. M. (1993) Molecular and cellular biology of cholinesterases. Prog. Neurobiol. 41, 31-91.
25. Newmeyer D. D., Farschon D. M., and Reed J. C. (1994) Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 79, 353-364.
26. Reiss Y., Layer P. G., and Kröger S. (1997) Butyrylcholinesterase-positive cells of the developing chicken retina that are noncholinergic and GABA-positive. Dev. Brain Res 100, 62-72.
27. Robitzki A., Mack A., Chatonnet A., and Layer P. G. (1997a) Transfection of reaggregating embryonic chicken retinal cells with an antisense 5′-DNA butyrylcholinesterase expression vector inhibits proliferation and alters morphogenesis. J. Neurochem. 69, 823-833.
28. Robitzki A., Mack A., Hoppe U., Chatonnet A., and Layer P. G. (1997b) Regulation of cholinesterase gene expression affects neuronal differentiation as revealed by transfection studies on reaggregating embryonic chicken retinal cells. Eur. J. Neurosci. 9, 2394-2405.
29. Schwartz L. M. and Milligan C. E. (1996) Cold thoughts of death: the role of ICE proteases in neuronal cell death. Trends Neurosci. 19, 555-562.
30. Soreq H. and Zakut H. (1993) Human Cholinesterases and Anticholinesterases. Academic Press, San Diego.
31. Taylor P. and Radic Z. (1994) The cholinesterases: from genes to proteins. Annu. Rev. Pharmacol. Toxicol. 34, 281-320.
32. Tsim K. W. K., Randall W. R., and Barnard E. A. (1988) Monoclonal antibodies specific for the different subunits of asymmetric acetylcholinesterase from chick muscle. J. Neurochem. 51, 95-104.
33. Weikert T., Rathjen F. G., and Layer P. G. (1990) Developmental maps of acetylcholinesterase and G4-antigen of the early chicken brain: long distance tracts originate from AChE-producing cell bodies. J. Neurobiol. 21, 484-498.
34. Willbold E. and Layer P. G. (1992) A hidden retinal regenerative capacity from the chick ciliary margin is reactivated in vitro, that is accompanied by down-regulation of butyrylcholinesterase Eur. J. Neurosci. 4, 210-220.
35. Willbold E. and Layer P. G. (1994) Butyrylcholinesterase regulates laminar retinogenesis of the chick embryo in vitro. Eur. J. Cell Biol. 64, 192-199.