Characterization of 12 silent alleles of the human butyrylcholinesterase (BCHE) gene

American Journal of Human Genetics

Volumn 58, Issue 1, 1996, Pages 52-64

  Primo Parmo, S L ^a   Bartels, C F ^b   Wiersema, B ^a   Van Der Spek, A F L ^a   Innis, J W ^a   La Du, B N ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; ENZYME ACTIVITY; ENZYME STRUCTURE; FEMALE; GENE EXPRESSION; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; MALE; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; PRIORITY JOURNAL; SILENT GENE;

EID: 0029655692     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Arnason A, Jensson O, Gudmundsson S (1975) Serum esterases of Icelanders. I. A "silent" pseudocholinesterase gene in an Icelandic family. Clin Genet 7:405-412
2. Arpagaus M, Chatonnet A, Masson P, Newton M, Vaughan TA, Bartels CF, Nogueira CP, et al (1991) Use of polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates. J Biol Chem 266:6966-6974
3. Arpagaus M, Fedon Y, Cousin X, Chatonnet A, Berge JB, Fournier D, Toutant JP (1994) cDNA, gene structure, and in vitro expression of ace-1, the gene encoding acetylcholinesterase of class A in the nematode Caenorhabditis elegans. J Biol Chem 269:9957-9965
4. Arpagaus M, Kott M, Vatsis KP, Bartels CF, La Du BN, Lockridge O ( 1990) Structure of the gene for human butyrylcholinesterase: evidence for a single copy. Biochemistry 29:124131
5. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidamn JG, Smith JA, Struhl K (1993) Current protocols in molecular biology, vol 2, section 9. John Wiley & Sons, New York, pp 9.1.1-9.1.4