Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate

Journal of Biological Chemistry

Volumn 277, Issue 47, 2002, Pages 45315-45322

  Okuda, Takashi ^a   Okamura, Michiko ^a   Kaitsuka, China ^b   Haga, Tatsuya ^b   Gurwitz, David ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b GAKUSHUIN UNIVERSITY   (Japan)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CLONING; GENES; NEUROLOGY; SODIUM; SUBSTRATES; SYNTHESIS (CHEMICAL);

POLYMORPHISM;

BIOCHEMISTRY;

CARRIER PROTEIN; CHLORIDE; CHOLINE; HEMICHOLINIUM 3; HIGH AFFINITY CHOLINE TRANSPORTER; ISOLEUCINE; NUCLEOTIDE; SODIUM; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; ASSAY; BINDING AFFINITY; BIOTINYLATION; CAENORHABDITIS ELEGANS; CELL SURFACE; CHOLINERGIC ACTIVITY; CHOLINERGIC NERVE CELL; CHT1 GENE; CONTROLLED STUDY; DNA POLYMORPHISM; EMBRYO; EXON; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE SEQUENCE; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION;

ACETYLCHOLINE; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHLORIDES; CHOLINE; HUMANS; JEWS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEURONS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN STRUCTURE, SECONDARY; RNA, MESSENGER; SEQUENCE ALIGNMENT; SODIUM; SPINAL CORD;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 0037160130     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207742200     Document Type: Article

References (36)

1. Tucek, S. (1985) J. Neurochem. 44, 11-24
2. Eiden, L. E. (1998) J. Neurochem. 70, 2227-2240
3. Parsons, S. M., Prior, C., and Marshall, I. G. (1993) Int. Rev. Neurobiol. 35, 279-390
4. Haga, T. (1971) J. Neurochem. 18, 781-798
5. Yamamura, H. I., and Snyder, S. H. (1972) Science 178, 626-628
6. Haga, T., and Noda, H. (1973) Biochim. Biophys. Acta 291, 564-575
7. Kuhar, M. J., and Murrin, L. C. (1978) J. Neurochem. 30, 15-21
8. Simon, J. R., and Kuhar, M. G. (1975) Nature 255, 162-163
9. Happe, H. K., and Murrin, L. C. (1993) J. Neurochem. 60, 1191-1201
10. Okuda, T., Haga, T., Kanai, Y., Endou, H., Ishihara, T., and Katsura, I. (2000) Nat. Neurosci. 3, 120-125
11. Okuda, T., and Haga, T. (2000) FEBS Lett. 484, 92-97
12. Reizer, J., Reizer, A., and Saier, M. H., Jr. (1994) Biochim. Biophys. Acta 1197, 133-166
13. Misawa, H., Nakata, K., Matsuura, J., Nagao, M., Okuda, T., and Haga, T. (2001) Neuroscience 105, 87-98
14. Lips, K. S., Pfeil, U., Haberberger, R. V., and Kummer, W. (2002) Cell Tissue Res. 307, 275-280
15. Kobayashi, Y., Okuda, T., Fujioka, Y., Matsumura, G., Nishimura, Y., and Haga, T. (2002) Neurosci. Lett. 317, 25-28
16. Apparsundaram, S., Ferguson, S. M., George, A. L., Jr., and Blakely, R. D. (2000) Biochem. Biophys. Res. Commun. 276, 862-867
17. Wang, Y., Cao, Z., Newkirk, R. F., Ivy, M. T., and Townsel, J. G. (2001) Gene (Amst.) 268, 123-131
18. Apparsundaram, S., Ferguson, S. M., and Blakely, R. D. (2001) Biochem. Soc. Trans. 29, 711-716
19. Guermonprez, L., O'Regan, S., Meunier, F. M., and Morot Gaudry-Talarmain, Y. (2002) J. Neurochem. 82, 874-884
20. Francis, P. T., Palmer, A. M., Snape, M., and Wilcock, G. K. (1999) J. Neurol. Neurosurg. Psychiatry 66, 137-147
21. Isacscn, O., Seo, H., Lin, L., Albeck, D., and Granholm, A. C. (2002) Trends Neurosci. 25, 79-84
22. Calabresi, P., Centonze, D., Gubellini, P., Pisani, A., and Bernardi, G. (2000) Trends Neurosci. 23, 120-126
23. Hyde, T. M., and Crock, J. M. (2001) J. Chem. Neuroanat. 22, 53-63
24. Slotkin, T. A., Nemeroff, C. B., Bissette, G., and Seidler, F. J. (1994) J. Clin. Invest. 94, 696-702
25. Bissette, G., Seidler, F. J., Nemeroff, C. B., and Slotkin, T. A. (1996) Ann. N. Y. Acad. Sci. 777, 197-204
26. Turk, E., Zabel, B., Mundlos, S., Dyer, J., and Wright, E. M. (1991) Nature 350, 354-356
27. Wright, E. M. (1998) Am. J. Physiol. 275, G879-G882
28. Fujiwara, H., Tatsumi, K., Miki, K., Harada, T., Miyai, K., Takai, S., and Amino, N. (1997) Nat. Genet. 16, 124-125
29. Maruyama, K., and Sugano, S. (1994) Gene (Amst.) 138, 171-174
30. Wang, H., Huang, W., Fei, Y. J., Xia, H., Yang-Feng, T. L., Leibach, F. H., Devoe, L. D., Ganapathy, V., and Prasad, P. D. (1999) J. Biol. Chem. 274, 14875-14883
31. Kuhar, M. J., and Zarbin, M. A. (1978) J. Neurochem. 31, 251-256
32. Collins, A., Lonjou, C., and Morton, N. E. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 15173-15177
33. Turk, E., and Wright, E. M. (1997) J. Membr. Biol. 159, 1-20
34. Varoqui, H., and Erickson, J. D. (1996) J. Biol. Chem. 271, 27229-27232
35. Song, H., Ming, G., Fon, E., Bellocchio, E., Edwards, R. H., and Poo, M. (1997) Neuron 18, 815-826
36. Ohno, K., Tsujino, A., Brengman, J. M., Harper, C. M., Bajzer, Z., Udd, B., Beyring, R., Robb, S., Kirkham, F. J., and Engel, A. G. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 2017-2022