메뉴 건너뛰기




Volumn 90, Issue 6, 2004, Pages 600-606

P53 expression, DNA ploidy and mitotic index as prognostic factors in patients with epithelial ovarian carcinoma

Author keywords

Genomic instability; Human; Mitotic index; Ovarian carcinoma; P53; Ploidy; Proliferation; Survival

Indexed keywords

PROTEIN P53; TOLONIUM CHLORIDE;

EID: 14244259710     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160409000612     Document Type: Article
Times cited : (7)

References (57)
  • 1
    • 0036024584 scopus 로고    scopus 로고
    • Ovarian cancer: Progress and continuing controversies in management
    • Moss C, Kaye SB: Ovarian cancer: progress and continuing controversies in management. Eur J Cancer, 38: 1701-1707, 2002.
    • (2002) Eur J Cancer , vol.38 , pp. 1701-1707
    • Moss, C.1    Kaye, S.B.2
  • 2
    • 0031026893 scopus 로고    scopus 로고
    • Epithelial ovarian carcinoma
    • Kristensen GB, Tropé C: Epithelial ovarian carcinoma. Lancet, 349: 113-117, 1997.
    • (1997) Lancet , vol.349 , pp. 113-117
    • Kristensen, G.B.1    Tropé, C.2
  • 4
    • 0347625462 scopus 로고    scopus 로고
    • Status of tumor markers in ovarian cancer screening
    • Bast RC Jr: Status of tumor markers in ovarian cancer screening. J Clin Oncol, 21 (Suppl 10): 200-205, 2003.
    • (2003) J Clin Oncol , vol.21 , Issue.SUPPL. 10 , pp. 200-205
    • Bast Jr., R.C.1
  • 6
    • 0031055966 scopus 로고    scopus 로고
    • Mib-1 evaluated proliferative activity in ovarian cancer with respect to prognostic significance
    • Marx D, Meden H, Brune T, Kron M, Korabiowska M, Kuhn W, Schauer A: Mib-1 evaluated proliferative activity in ovarian cancer with respect to prognostic significance. Anticancer Res, 17: 775-780, 1997.
    • (1997) Anticancer Res , vol.17 , pp. 775-780
    • Marx, D.1    Meden, H.2    Brune, T.3    Kron, M.4    Korabiowska, M.5    Kuhn, W.6    Schauer, A.7
  • 7
    • 0031754358 scopus 로고    scopus 로고
    • DNA content and S-phase fraction in epithelial ovarian cancer: What information do they really add?
    • Braly P: DNA content and S-phase fraction in epithelial ovarian cancer: what information do they really add? Gynecol Oncol, 71: 1-2, 1998.
    • (1998) Gynecol Oncol , vol.71 , pp. 1-2
    • Braly, P.1
  • 8
    • 0031709216 scopus 로고    scopus 로고
    • Molecular pathology of ovarian carcinomas
    • Matias-Guiu X, Prat J: Molecular pathology of ovarian carcinomas. Virchows Arch, 433: 103-111, 1998.
    • (1998) Virchows Arch , vol.433 , pp. 103-111
    • Matias-Guiu, X.1    Prat, J.2
  • 9
    • 0023281280 scopus 로고
    • International Federation of Gynecology and Obstetrics: Changes in definition of clinical staging for carcinoma of the cervix and the ovary
    • International Federation of Gynecology and Obstetrics: Changes in definition of clinical staging for carcinoma of the cervix and the ovary. Am J Obstet Gynecol, 56: 263-264, 1987.
    • (1987) Am J Obstet Gynecol , vol.56 , pp. 263-264
  • 10
    • 0030847899 scopus 로고    scopus 로고
    • Cell proliferation as an independent predictor of survival for patients with advanced nasopharyngeal carcinoma
    • Faccioli S, Cavicchi O, Caliceti U, Rinaldi Ceroni A, Chieco P: Cell proliferation as an independent predictor of survival for patients with advanced nasopharyngeal carcinoma. Mod Pathol, 10: 884-894, 1997.
    • (1997) Mod Pathol , vol.10 , pp. 884-894
    • Faccioli, S.1    Cavicchi, O.2    Caliceti, U.3    Rinaldi Ceroni, A.4    Chieco, P.5
  • 11
    • 0031741123 scopus 로고    scopus 로고
    • Retinoblastoma (RB1) gene product expression in breast carcinoma. Correlation with Ki-67 growth fraction and biopathological profile
    • Ceccarelli C, Santini D, Chieco P, Taffurelli M, Gamberini M, Pileri S, Marrano D: Retinoblastoma (RB1) gene product expression in breast carcinoma. Correlation with Ki-67 growth fraction and biopathological profile. J Clin Pathol, 51: 818-824, 1998.
    • (1998) J Clin Pathol , vol.51 , pp. 818-824
    • Ceccarelli, C.1    Santini, D.2    Chieco, P.3    Taffurelli, M.4    Gamberini, M.5    Pileri, S.6    Marrano, D.7
  • 12
    • 0027239691 scopus 로고
    • A rapid and simple staining method, using toluidine blue, for analysing mitotic figures in tissue sections
    • Chieco P, Pagnoni M, Romagnoli E, Melchiorri C: A rapid and simple staining method, using toluidine blue, for analysing mitotic figures in tissue sections. Histochem J, 25: 569-577, 1993.
    • (1993) Histochem J , vol.25 , pp. 569-577
    • Chieco, P.1    Pagnoni, M.2    Romagnoli, E.3    Melchiorri, C.4
  • 13
    • 0028064419 scopus 로고
    • Diagnostic and prognostic value of DNA ploidy and cell nuclearity in ultrasound-guided liver biopsies
    • Melchiorri C, Bolondi L, Chieco P, Pagnoni M, Gramantieri L, Barbara L: Diagnostic and prognostic value of DNA ploidy and cell nuclearity in ultrasound-guided liver biopsies. Cancer, 74: 1713-1719, 1994.
    • (1994) Cancer , vol.74 , pp. 1713-1719
    • Melchiorri, C.1    Bolondi, L.2    Chieco, P.3    Pagnoni, M.4    Gramantieri, L.5    Barbara, L.6
  • 15
    • 0026100438 scopus 로고
    • A multifaced DNA ploidy analysis to determine ovarian carcinoma aggressiveness
    • Chieco P, Melchiorri C, Lisignoli G, Marabini A, Orlandi: A multifaced DNA ploidy analysis to determine ovarian carcinoma aggressiveness. Cancer, 67: 1878-1885, 1991.
    • (1991) Cancer , vol.67 , pp. 1878-1885
    • Chieco, P.1    Melchiorri, C.2    Lisignoli, G.3    Marabini, A.4    Orlandi5
  • 16
    • 33845382806 scopus 로고
    • Nonparametric estimation for incomplete observations
    • Kaplan EL, Meier P: Nonparametric estimation for incomplete observations. J Am Statist Assoc, 53: 457-481, 1958.
    • (1958) J Am Statist Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 19
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR: Regression models and life tables (with discussion). J R Statist Soc, B3: 197-220, 1972.
    • (1972) J R Statist Soc , vol.B3 , pp. 197-220
    • Cox, D.R.1
  • 20
    • 84952094529 scopus 로고
    • Detection of influential observations in linear regression
    • Cook RD: Detection of influential observations in linear regression. Technometrics, 19: 15-18, 1977.
    • (1977) Technometrics , vol.19 , pp. 15-18
    • Cook, R.D.1
  • 21
    • 0023095251 scopus 로고
    • Tumor cell instability, diversification and progression to the metastatic phenotype: From oncogene to oncofetal expression
    • Nicolson GL: Tumor cell instability, diversification and progression to the metastatic phenotype: from oncogene to oncofetal expression. Cancer Res, 47: 1473-1487, 1987.
    • (1987) Cancer Res , vol.47 , pp. 1473-1487
    • Nicolson, G.L.1
  • 22
    • 0022600767 scopus 로고
    • Mechanisms of tumor progression
    • Nowell PC: Mechanisms of tumor progression. Cancer Res, 46: 2203-2207, 1986.
    • (1986) Cancer Res , vol.46 , pp. 2203-2207
    • Nowell, P.C.1
  • 23
    • 14244257970 scopus 로고
    • Chromosomes and cancer: The evolution of an idea
    • Nowell PC: Chromosomes and cancer: the evolution of an idea. Adv Cancer Res, 62: 1-18, 1993.
    • (1993) Adv Cancer Res , vol.62 , pp. 1-18
    • Nowell, P.C.1
  • 25
    • 0032506125 scopus 로고    scopus 로고
    • Genetic instability of cancer cells is proportional to their degree of aneuploidy
    • Duesberg P, Rausch C, Rasnik D, Hehlmann R: Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proc Natl Acad Sci (USA), 95: 13692-13697, 1998.
    • (1998) Proc Natl Acad Sci (USA) , vol.95 , pp. 13692-13697
    • Duesberg, P.1    Rausch, C.2    Rasnik, D.3    Hehlmann, R.4
  • 27
    • 0024399684 scopus 로고
    • Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis
    • Weinberg RA: Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res, 49: 3713-3721, 1989.
    • (1989) Cancer Res , vol.49 , pp. 3713-3721
    • Weinberg, R.A.1
  • 28
    • 0027202321 scopus 로고
    • Cell cycle control, DNA repair and initiation of carcinogenesis
    • Kaufmann WK, Kaufmann DG: Cell cycle control, DNA repair and initiation of carcinogenesis. FASEB J, 7: 188-191, 1993.
    • (1993) FASEB J , vol.7 , pp. 188-191
    • Kaufmann, W.K.1    Kaufmann, D.G.2
  • 31
    • 0024315022 scopus 로고
    • Prognosis of ovarian carcinomas: Prediction by histoquantitative methods
    • Haapasalo H, Collan Y, Atkin NB, Pesonen E, Seppä A: Prognosis of ovarian carcinomas: prediction by histoquantitative methods. Histopathology, 15: 167-178, 1989.
    • (1989) Histopathology , vol.15 , pp. 167-178
    • Haapasalo, H.1    Collan, Y.2    Atkin, N.B.3    Pesonen, E.4    Seppä, A.5
  • 32
    • 0032801588 scopus 로고    scopus 로고
    • Lack of prognostic significance of ploidy and S-phase measurements in advanced ovarian cancer
    • Coley HM, Sargent JM, Titley J, Taylor CG: Lack of prognostic significance of ploidy and S-phase measurements in advanced ovarian cancer. Anticancer Res, 19: 2111-2116, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 2111-2116
    • Coley, H.M.1    Sargent, J.M.2    Titley, J.3    Taylor, C.G.4
  • 33
    • 0034989378 scopus 로고    scopus 로고
    • Are DNA ploidy and epidermal growth factor receptor prognostic factors for untreated ovarian cancer? A prospective study
    • Nagai N, Oshita T, Fujii T, Katsube Y, Matsubayashi S, Ohama K: Are DNA ploidy and epidermal growth factor receptor prognostic factors for untreated ovarian cancer? A prospective study. Am J Clin Oncol, 24: 215-221, 2001.
    • (2001) Am J Clin Oncol , vol.24 , pp. 215-221
    • Nagai, N.1    Oshita, T.2    Fujii, T.3    Katsube, Y.4    Matsubayashi, S.5    Ohama, K.6
  • 34
    • 0034988636 scopus 로고    scopus 로고
    • Cell proliferation in ovarian carcinoma: Superior accuracy of S-phase fraction (SPF) by DNA labeling index versus flow cytometric SPF, lack of independent prognostic power for SPF and DNA ploidy, and limited effect of SPF on tumor growth rate
    • Meyer JS, Gersell DJ, Yim S: Cell proliferation in ovarian carcinoma: superior accuracy of S-phase fraction (SPF) by DNA labeling index versus flow cytometric SPF, lack of independent prognostic power for SPF and DNA ploidy, and limited effect of SPF on tumor growth rate. Gynecol Oncol, 81: 466-476, 2001.
    • (2001) Gynecol Oncol , vol.81 , pp. 466-476
    • Meyer, J.S.1    Gersell, D.J.2    Yim, S.3
  • 35
    • 0036144083 scopus 로고    scopus 로고
    • Multivariate analysis of the prognostic significance of DNA-ploidy and S-phase fraction in ovarian cancer determined by flow cytometry following detection of cytokeratin-labeled tumor cells
    • Kimmig R, Wimberger P, Hillemanns P, Kapsner T, Caspari C, Hepp H: Multivariate analysis of the prognostic significance of DNA-ploidy and S-phase fraction in ovarian cancer determined by flow cytometry following detection of cytokeratin-labeled tumor cells. Gynecol Oncol, 84: 21-31, 2002.
    • (2002) Gynecol Oncol , vol.84 , pp. 21-31
    • Kimmig, R.1    Wimberger, P.2    Hillemanns, P.3    Kapsner, T.4    Caspari, C.5    Hepp, H.6
  • 36
    • 0036338490 scopus 로고    scopus 로고
    • Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary
    • Itamochi H, Kigawa J, Sugiyama T, Kikuchi Y, Suzuki M, Terakawa N: Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary. Obstet Gynecol, 100: 281-287, 2002.
    • (2002) Obstet Gynecol , vol.100 , pp. 281-287
    • Itamochi, H.1    Kigawa, J.2    Sugiyama, T.3    Kikuchi, Y.4    Suzuki, M.5    Terakawa, N.6
  • 37
    • 0032747069 scopus 로고    scopus 로고
    • Volume-corrected mitotic index and P53 immunoreactivity in borderline and malignant epithelial ovarian tumors
    • Miliaras D: Volume-corrected mitotic index and P53 immunoreactivity in borderline and malignant epithelial ovarian tumors. Anal Quant Cytol Histol, 21: 425-429, 1999.
    • (1999) Anal Quant Cytol Histol , vol.21 , pp. 425-429
    • Miliaras, D.1
  • 38
    • 0032437296 scopus 로고    scopus 로고
    • P53 in breast carcinomas: Association between the presence of mutation and immunohistochemical expression using a semiquantitative approach
    • Schmitt FC, Soares R, Cirnes L, Seruca R: P53 in breast carcinomas: association between the presence of mutation and immunohistochemical expression using a semiquantitative approach. Pathol Res Pract, 194: 815-819, 1998.
    • (1998) Pathol Res Pract , vol.194 , pp. 815-819
    • Schmitt, F.C.1    Soares, R.2    Cirnes, L.3    Seruca, R.4
  • 39
    • 0031723620 scopus 로고    scopus 로고
    • Demystified... p53
    • Darnton SJ: Demystified... p53. Mol Pathol, 51: 248-253, 1998.
    • (1998) Mol Pathol , vol.51 , pp. 248-253
    • Darnton, S.J.1
  • 41
    • 0031948286 scopus 로고    scopus 로고
    • p53 in tumor progression: Life, death, and everything
    • Mowat MRA: p53 in tumor progression: life, death, and everything. Adv Cancer Res, 74: 25-48, 1998.
    • (1998) Adv Cancer Res , vol.74 , pp. 25-48
    • Mowat, M.R.A.1
  • 42
    • 0029845760 scopus 로고    scopus 로고
    • Structure and function of p53 tumor suppressor gene: Clues for rational cancer therapeutic strategies
    • Harris CC: Structure and function of p53 tumor suppressor gene: clues for rational cancer therapeutic strategies. J Natl Cancer Inst, 88: 1442-1455, 1996.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1442-1455
    • Harris, C.C.1
  • 43
    • 0037627875 scopus 로고    scopus 로고
    • Why did p53 gene therapy fail in ovarian cancer?
    • Zeimet AG, Marth C: Why did p53 gene therapy fail in ovarian cancer? Lancet Oncol, 4: 415-422, 2003.
    • (2003) Lancet Oncol , vol.4 , pp. 415-422
    • Zeimet, A.G.1    Marth, C.2
  • 44
    • 0027331811 scopus 로고
    • p53 accumulation in ovarian carcinomas and its prognostic implications
    • Bosari S, Viale G, Radaelli U, Bossi P, Bonoldi E, Coggi G: p53 accumulation in ovarian carcinomas and its prognostic implications. Hum Pathol, 24: 1175-1179, 1993.
    • (1993) Hum Pathol , vol.24 , pp. 1175-1179
    • Bosari, S.1    Viale, G.2    Radaelli, U.3    Bossi, P.4    Bonoldi, E.5    Coggi, G.6
  • 45
    • 0027945491 scopus 로고
    • Alteration of p53 gene in ovarian carcinoma: Clinicopathological correlation and prognostic significance
    • Niwa K, Itoh M, Murase T, Morishita S, Itoh N, Mori H, Tamaya T: Alteration of p53 gene in ovarian carcinoma: clinicopathological correlation and prognostic significance. Br J Cancer, 70: 1191-1197, 1994.
    • (1994) Br J Cancer , vol.70 , pp. 1191-1197
    • Niwa, K.1    Itoh, M.2    Murase, T.3    Morishita, S.4    Itoh, N.5    Mori, H.6    Tamaya, T.7
  • 48
    • 0032077390 scopus 로고    scopus 로고
    • Expression of the p53 tumour suppressor gene as a prognostic marker in platinum-treated patients with ovarian cancer
    • Marx D, Meden H, Ziemek T, Lenthe T, Kuhn W, Schauer A: Expression of the p53 tumour suppressor gene as a prognostic marker in platinum-treated patients with ovarian cancer. Eur J Cancer, 34: 845-850, 1998.
    • (1998) Eur J Cancer , vol.34 , pp. 845-850
    • Marx, D.1    Meden, H.2    Ziemek, T.3    Lenthe, T.4    Kuhn, W.5    Schauer, A.6
  • 49
    • 0036919875 scopus 로고    scopus 로고
    • Prognostic value of P53 accumulation in epithelial ovarian carcinomas
    • Berker B, Dunder I, Ensari A, Cengiz SD: Prognostic value of P53 accumulation in epithelial ovarian carcinomas. Arch Gynecol Obstet, 266: 205-209, 2002.
    • (2002) Arch Gynecol Obstet , vol.266 , pp. 205-209
    • Berker, B.1    Dunder, I.2    Ensari, A.3    Cengiz, S.D.4
  • 50
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • Giaccia AJ, Kastan MB: The complexity of p53 modulation: emerging patterns from divergent signals. Genes Develop, 12: 2973-2983, 1998.
    • (1998) Genes Develop , vol.12 , pp. 2973-2983
    • Giaccia, A.J.1    Kastan, M.B.2
  • 51
    • 3543029166 scopus 로고    scopus 로고
    • Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: Apoptosis and the cell cycle arrest
    • Wilson JW, Pritchard DM, Hickman JA, Potten CS: Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: apoptosis and the cell cycle arrest. Am J Pathol, 153: 899-909, 1998.
    • (1998) Am J Pathol , vol.153 , pp. 899-909
    • Wilson, J.W.1    Pritchard, D.M.2    Hickman, J.A.3    Potten, C.S.4
  • 53
    • 0030892447 scopus 로고    scopus 로고
    • Long-term survival and DNA ploidy in advanced epithelial ovarian cancer
    • Resnik E, Trujillo YP, Taxy JB: Long-term survival and DNA ploidy in advanced epithelial ovarian cancer. J Surg Oncol, 64: 299-303, 1997.
    • (1997) J Surg Oncol , vol.64 , pp. 299-303
    • Resnik, E.1    Trujillo, Y.P.2    Taxy, J.B.3
  • 56
    • 0035653494 scopus 로고    scopus 로고
    • Prognostic importance of DNA ploidy and p53 in early stages of epithelial ovarian carcinoma
    • Skirnisdottir I, Sorbe B, Karlsson M, Seidal T: Prognostic importance of DNA ploidy and p53 in early stages of epithelial ovarian carcinoma. Int J Oncol, 19: 1295-1302, 2001.
    • (2001) Int J Oncol , vol.19 , pp. 1295-1302
    • Skirnisdottir, I.1    Sorbe, B.2    Karlsson, M.3    Seidal, T.4
  • 57
    • 0031869758 scopus 로고    scopus 로고
    • Predicting response to cancer chemotherapy: The role of p53
    • Weller M: Predicting response to cancer chemotherapy: the role of p53. Cell Tissue Res, 292: 435-445, 1998.
    • (1998) Cell Tissue Res , vol.292 , pp. 435-445
    • Weller, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.