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Volumn 51, Issue 11, 1998, Pages 818-824

Retinoblastoma (RB1) gene product expression in breast carcinoma. Correlation with Ki-67 growth fraction and biopathological profile

Author keywords

Breast cancer; Immunohistochemistry; pRb; Retinoblastoma

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR; GENE PRODUCT; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 0031741123     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.51.11.818     Document Type: Article
Times cited : (34)

References (47)
  • 1
    • 0028991396 scopus 로고
    • Mutation of cell cycle regulators. Biological and clinical implications for human neoplasia
    • Cordon-Cardo C. Mutation of cell cycle regulators. Biological and clinical implications for human neoplasia. Am J Pathol 1995;147:545-60.
    • (1995) Am J Pathol , vol.147 , pp. 545-560
    • Cordon-Cardo, C.1
  • 2
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumor suppressor protein and the viral oncoproteins
    • Nevins JR. E2F: a link between the Rb tumor suppressor protein and the viral oncoproteins. Science 1992;258:424-9.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 4
    • 0010627282 scopus 로고
    • How the retinoblastoina gene may inhibit cell growth
    • Marx J. How the retinoblastoina gene may inhibit cell growth. Science 1991;252:1492.
    • (1991) Science , vol.252 , pp. 1492
    • Marx, J.1
  • 5
    • 0028861428 scopus 로고
    • Inhibition of apoptosis by the retinoblastoma gene product
    • Haas-Kogan DA, Kogan SC, Levi D, et al. Inhibition of apoptosis by the retinoblastoma gene product. EMBO J 1995;14:461-72.
    • (1995) EMBO J , vol.14 , pp. 461-472
    • Haas-Kogan, D.A.1    Kogan, S.C.2    Levi, D.3
  • 6
    • 0027263505 scopus 로고
    • Retinoblastoma (Rb) gene product expression in lymphomas. Correlation with Ki-67 growth fraction
    • Martinez JC, Piris MA, Sanchez-Beato M, et al. Retinoblastoma (Rb) gene product expression in lymphomas. Correlation with Ki-67 growth fraction. J Pathol 1993;169: 405-12.
    • (1993) J Pathol , vol.169 , pp. 405-412
    • Martinez, J.C.1    Piris, M.A.2    Sanchez-Beato, M.3
  • 7
    • 0028951023 scopus 로고
    • Expression of the retinoblastoma gene product in human hepatocellular carcinoma
    • Seki S, Kawakita N, Yanai A, et al. Expression of the retinoblastoma gene product in human hepatocellular carcinoma. Hum Pathol 1995;26:366-74.
    • (1995) Hum Pathol , vol.26 , pp. 366-374
    • Seki, S.1    Kawakita, N.2    Yanai, A.3
  • 8
    • 0029979182 scopus 로고    scopus 로고
    • Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity
    • Jares P, Campo E, Pinyol M, et al. Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity. Am J Pathol 1996;148:1591-600.
    • (1996) Am J Pathol , vol.148 , pp. 1591-1600
    • Jares, P.1    Campo, E.2    Pinyol, M.3
  • 9
    • 0029111421 scopus 로고
    • Determination of the prognostic value of cyclin D1 overexpression in breast cancer
    • McIntosh GG, Anderson JJ, Milton I, et al. Determination of the prognostic value of cyclin D1 overexpression in breast cancer. Oncogene 1995;11:885-91.
    • (1995) Oncogene , vol.11 , pp. 885-891
    • McIntosh, G.G.1    Anderson, J.J.2    Milton, I.3
  • 10
    • 0020518746 scopus 로고
    • Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
    • Cavenee WK, Dryja TP, Philips RA, et al. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 1983;305:779-84.
    • (1983) Nature , vol.305 , pp. 779-784
    • Cavenee, W.K.1    Dryja, T.P.2    Philips, R.A.3
  • 11
    • 0023686773 scopus 로고
    • Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
    • Harbour JW, Lai S-L, Whang-Peng J, et al. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 1988;241:353-7.
    • (1988) Science , vol.241 , pp. 353-357
    • Harbour, J.W.1    Lai, S.-L.2    Whang-Peng, J.3
  • 12
    • 0024318865 scopus 로고
    • Structural alterations of the RB1 gene in human soft tissue tumours
    • Stratton MR, Williams S, Fisher C, et al. Structural alterations of the RB1 gene in human soft tissue tumours. Br J Cancer 1989;60:202-5.
    • (1989) Br J Cancer , vol.60 , pp. 202-205
    • Stratton, M.R.1    Williams, S.2    Fisher, C.3
  • 13
    • 0024500043 scopus 로고
    • Point mutational inactivation of the retinoblastoma antioncogene
    • Horowitz JM, Park S-H, Bogenmann E, et al. Point mutational inactivation of the retinoblastoma antioncogene. Science 1989;243:937-40.
    • (1989) Science , vol.243 , pp. 937-940
    • Horowitz, J.M.1    Park, S.-H.2    Bogenmann, E.3
  • 14
    • 0013608735 scopus 로고
    • Molecular biology of the human retinoblastoma gene
    • Klein G, ed. New York: Marcel Dekker
    • Lee WH, Bookstein RE, Lee EYHP. Molecular biology of the human retinoblastoma gene. In: Klein G, ed. Tumour suppressor genes. New York: Marcel Dekker, 1990:160-99.
    • (1990) Tumour Suppressor Genes , pp. 160-199
    • Lee, W.H.1    Bookstein, R.E.2    Lee, E.Y.H.P.3
  • 15
    • 0027969249 scopus 로고
    • Molecular analysis of the retinoblastoma gene in primary ovarian cancer cells
    • Liu Y, Heyman M, Wang Y, et al. Molecular analysis of the retinoblastoma gene in primary ovarian cancer cells. Int J Cancer 1994;58:663-7.
    • (1994) Int J Cancer , vol.58 , pp. 663-667
    • Liu, Y.1    Heyman, M.2    Wang, Y.3
  • 16
    • 0024286232 scopus 로고
    • Structural rearrangement of the retinoblastoma gene in human breast carcinoma
    • T'Ang A, Varley JM, Chakraborty S, et al. Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science 1988;242:263-6.
    • (1988) Science , vol.242 , pp. 263-266
    • T'Ang, A.1    Varley, J.M.2    Chakraborty, S.3
  • 17
    • 0024281617 scopus 로고
    • Inactivation of the retinoblastoma susceptibility gene in human breast cancers
    • Lee EY, To H, Shew J-Y, et al. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 1988;241:218-21.
    • (1988) Science , vol.241 , pp. 218-221
    • Lee, E.Y.1    To, H.2    Shew, J.-Y.3
  • 18
    • 0024309158 scopus 로고
    • The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumors
    • Varley JM, Armour J, Swallow JE, et al. The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumors. Oncogene 1989;4:725-9.
    • (1989) Oncogene , vol.4 , pp. 725-729
    • Varley, J.M.1    Armour, J.2    Swallow, J.E.3
  • 19
    • 0027078657 scopus 로고
    • Retinoblastoma and p53 gene product expression in breast carcinoma: Immunohistochemical analysis and clinicopathologic correlation
    • Trudel M, Mulligan L, Cavenee W, et al. Retinoblastoma and p53 gene product expression in breast carcinoma: immunohistochemical analysis and clinicopathologic correlation. Hum Pathol 1992;23:1388-94.
    • (1992) Hum Pathol , vol.23 , pp. 1388-1394
    • Trudel, M.1    Mulligan, L.2    Cavenee, W.3
  • 20
    • 0026729463 scopus 로고
    • The retinoblastoma gene in breast cancer; allele loss is not correlated with loss of gene protein expression
    • Borg A, Zhang Q-X, Alm P, et al. The retinoblastoma gene in breast cancer; allele loss is not correlated with loss of gene protein expression. Cancer Res 1992;52:2991-4.
    • (1992) Cancer Res , vol.52 , pp. 2991-2994
    • Borg, A.1    Zhang, Q.-X.2    Alm, P.3
  • 21
    • 0025323366 scopus 로고
    • Role of the retinoblastoma gene in the initiation and progression of human cancer
    • Benedict WF, Xu HJ, Hu SX, et al. Role of the retinoblastoma gene in the initiation and progression of human cancer. J Clin Invest 1990;85:988-93.
    • (1990) J Clin Invest , vol.85 , pp. 988-993
    • Benedict, W.F.1    Xu, H.J.2    Hu, S.X.3
  • 22
    • 0028036251 scopus 로고
    • Evidence of functional RB protein in epithelial ovarian carcinomas despite loss of heterozygosity at the RBG locus
    • Dodson MK, Cliby WA, Xu H-J, et al. Evidence of functional RB protein in epithelial ovarian carcinomas despite loss of heterozygosity at the RBG locus. Cancer Res 1994;54:610-13.
    • (1994) Cancer Res , vol.54 , pp. 610-613
    • Dodson, M.K.1    Cliby, W.A.2    Xu, H.-J.3
  • 23
    • 0029981711 scopus 로고    scopus 로고
    • Tumor suppressor genes and related molecules in leiomyosarcoma
    • Dei Tos AP, Maestro R, Doglioni C, et al. Tumor suppressor genes and related molecules in leiomyosarcoma. Am J Pathol 1996;148:1037-45.
    • (1996) Am J Pathol , vol.148 , pp. 1037-1045
    • Dei Tos, A.P.1    Maestro, R.2    Doglioni, C.3
  • 24
    • 0026738802 scopus 로고
    • Retinoblastoma and p53 gene expression related to relapse and survival in human breast cancer: An immunohistochemical study
    • Sawan A, Randall B, Angus B, et al. Retinoblastoma and p53 gene expression related to relapse and survival in human breast cancer: an immunohistochemical study. J Pathol 1992;168;23-8.
    • (1992) J Pathol , vol.168 , pp. 23-28
    • Sawan, A.1    Randall, B.2    Angus, B.3
  • 25
    • 0028418103 scopus 로고
    • Expression of retinoblastoma protein in human breast cancer: An immunohistochemical study
    • Bianchi S, Calzolari A, Giannelli E, et al. Expression of retinoblastoma protein in human breast cancer: an immunohistochemical study. Pathologica 1995;86:146-9.
    • (1995) Pathologica , vol.86 , pp. 146-149
    • Bianchi, S.1    Calzolari, A.2    Giannelli, E.3
  • 26
    • 0028951667 scopus 로고
    • Expression of retinoblastoma gene protien (Rb) in breast cancer as related to established prognostic factors and survival
    • Pietilainen T, Lipponen P, Aaltomaa S, et al. Expression of retinoblastoma gene protien (Rb) in breast cancer as related to established prognostic factors and survival. Eur J Cancer 1995;31A:329-33.
    • (1995) Eur J Cancer , vol.31 A , pp. 329-333
    • Pietilainen, T.1    Lipponen, P.2    Aaltomaa, S.3
  • 27
    • 10244246508 scopus 로고    scopus 로고
    • Retinoblastoma protein in human breast carcinoma: Immunohistochemical study using a new monoclonal antibody effective on routinely processed tissues
    • Anderson JJ, Tinaikos DG, McIntosh GG, et al. Retinoblastoma protein in human breast carcinoma: immunohistochemical study using a new monoclonal antibody effective on routinely processed tissues. J Pathol 1996;180: 65-70.
    • (1996) J Pathol , vol.180 , pp. 65-70
    • Anderson, J.J.1    Tinaikos, D.G.2    McIntosh, G.G.3
  • 28
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. the value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up. Histopathology 1991;19:403-10.
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 29
    • 0027419982 scopus 로고
    • Demonstration of cytokeratin intermediate filaments in oocytes of the developing and adult human ovary
    • Santini D, Ceccarelli C, Mazzoleni G, et al. Demonstration of cytokeratin intermediate filaments in oocytes of the developing and adult human ovary. Histochemistry 1993;99: 311-19.
    • (1993) Histochemistry , vol.99 , pp. 311-319
    • Santini, D.1    Ceccarelli, C.2    Mazzoleni, G.3
  • 30
    • 0023261635 scopus 로고
    • The retinoblastoma susceptibility gene encodes a nuclear phosphoprotem associated with DNA binding activity
    • Lee WH, Shew JY, Hong FD, et al. The retinoblastoma susceptibility gene encodes a nuclear phosphoprotem associated with DNA binding activity. Nature 1988;329:642-5.
    • (1988) Nature , vol.329 , pp. 642-645
    • Lee, W.H.1    Shew, J.Y.2    Hong, F.D.3
  • 31
    • 0030000639 scopus 로고    scopus 로고
    • Cytometric measurement of cell proliferation in echo-guided biopsies from focal lesions of the liver
    • Faccioli S, Chieco P, Gramantieri L, et al. Cytometric measurement of cell proliferation in echo-guided biopsies from focal lesions of the liver. Mod Pathol 1996;9:120-5.
    • (1996) Mod Pathol , vol.9 , pp. 120-125
    • Faccioli, S.1    Chieco, P.2    Gramantieri, L.3
  • 32
    • 0026040813 scopus 로고
    • Quantitative study of Ki-67 antibody staining in non-Hodgkin's lymphoma using image analysis
    • Caulet S, Lesty C, Raphael M, et al. Quantitative study of Ki-67 antibody staining in non-Hodgkin's lymphoma using image analysis. Anal Quant Cytol Histol 1991;13:279-87.
    • (1991) Anal Quant Cytol Histol , vol.13 , pp. 279-287
    • Caulet, S.1    Lesty, C.2    Raphael, M.3
  • 33
    • 0027239691 scopus 로고
    • A rapid and simple staining method using toluidine blue for analysing mitotic figures in tissue sections
    • Chieco P, Pagnoni M, Romagnoli E, et al. A rapid and simple staining method using toluidine blue for analysing mitotic figures in tissue sections. Histochem J 1993;25:569-77.
    • (1993) Histochem J , vol.25 , pp. 569-577
    • Chieco, P.1    Pagnoni, M.2    Romagnoli, E.3
  • 35
    • 0027267730 scopus 로고
    • Valeur pronostique d'une variable continue et point de césure optimal
    • Hill C. Valeur pronostique d'une variable continue et point de césure optimal. Bull Cancer 1993;80:649-52.
    • (1993) Bull Cancer , vol.80 , pp. 649-652
    • Hill, C.1
  • 36
    • 15644373844 scopus 로고
    • Multiple regression and correlation part 2. Advanced applications
    • Bernstein IH, ed. New York: Springer Verlag
    • Bernstein IH, Garbin CP, Teng GK. Multiple regression and correlation part 2. Advanced applications. In: Bernstein IH, ed. Applied multivariate analysis . New York: Springer Verlag, 1988;123-4.
    • (1988) Applied Multivariate Analysis , pp. 123-124
    • Bernstein, I.H.1    Garbin, C.P.2    Teng, G.K.3
  • 37
    • 0028929726 scopus 로고
    • Multiple expression patterns of biopathological markers in primary invasive breast carcinoma: A useful tool for elucidating its biological behaviour
    • Ceccarelli C, Santini D, Chieco P, et al. Multiple expression patterns of biopathological markers in primary invasive breast carcinoma: a useful tool for elucidating its biological behaviour. Ann Oncol 1995;6:275-82.
    • (1995) Ann Oncol , vol.6 , pp. 275-282
    • Ceccarelli, C.1    Santini, D.2    Chieco, P.3
  • 39
    • 0031023425 scopus 로고    scopus 로고
    • Deregulation of cyclin e and D1 in breast cancer is associated with inactivation of the retinoblastoma protein
    • Nieslen NH, Emdin SO, Cajander J, et al. Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein. Oncogene 1997;14: 295-304.
    • (1997) Oncogene , vol.14 , pp. 295-304
    • Nieslen, N.H.1    Emdin, S.O.2    Cajander, J.3
  • 40
    • 0002187866 scopus 로고    scopus 로고
    • Putative roles of retinoblastoma protein in apoptosis
    • Ping Dou Q. Putative roles of retinoblastoma protein in apoptosis. Apoptosis 1997;2:5-18.
    • (1997) Apoptosis , vol.2 , pp. 5-18
    • Ping Dou, Q.1
  • 41
    • 0028276571 scopus 로고
    • Expression of the retinoblastoma protein is regulated in normal human tissues
    • Cordon-Cardo C, Richon VM. Expression of the retinoblastoma protein is regulated in normal human tissues. Am J Pathol 1994;144:500-10.
    • (1994) Am J Pathol , vol.144 , pp. 500-510
    • Cordon-Cardo, C.1    Richon, V.M.2
  • 42
    • 0031107250 scopus 로고    scopus 로고
    • The epidermal growth factor receptor in breast cancer
    • Fox SB, Harris AL. The epidermal growth factor receptor in breast cancer. J Mammary Gland Biol Neoplasia 1997;2: 131-41.
    • (1997) J Mammary Gland Biol Neoplasia , vol.2 , pp. 131-141
    • Fox, S.B.1    Harris, A.L.2
  • 43
    • 0028127473 scopus 로고
    • The neu-oncogene: More than a prognostic indicator?
    • De Potter CR. The neu-oncogene: more than a prognostic indicator? Hum Pathol 1994;25:1264-8.
    • (1994) Hum Pathol , vol.25 , pp. 1264-1268
    • De Potter, C.R.1
  • 45
    • 0029793758 scopus 로고    scopus 로고
    • Differentiation pathways in primary invasive breast carcinoma as suggested by intermediate filament and biopathological marker expression
    • Santini D, Ceccarelli C, Taffurelli M, et al. Differentiation pathways in primary invasive breast carcinoma as suggested by intermediate filament and biopathological marker expression. J Pathol 1996;179;386-91.
    • (1996) J Pathol , vol.179 , pp. 386-391
    • Santini, D.1    Ceccarelli, C.2    Taffurelli, M.3
  • 46
    • 0031016323 scopus 로고    scopus 로고
    • Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior
    • Hendrix MJC, Seftor EA, Seftor REB, et al. Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior. Am J Pathol 1997;150:483-95.
    • (1997) Am J Pathol , vol.150 , pp. 483-495
    • Hendrix, M.J.C.1    Seftor, E.A.2    Seftor, R.E.B.3
  • 47
    • 0344727060 scopus 로고    scopus 로고
    • p21waf1/cip1 and terminal differentiation control of normal epithelia
    • Missero C, Dotto GP. p21waf1/cip1 and terminal differentiation control of normal epithelia. Mol Cell Diff 1996;4:1 16.
    • (1996) Mol Cell Diff , vol.4 , pp. 116
    • Missero, C.1    Dotto, G.P.2


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