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Volumn 60, Issue 2, 2005, Pages 110-114

Glyceride derivatives as potential prodrugs: Synthesis, biological activity and kinetic studies of glyceride derivatives of mefenamic acid

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIHYDROXY 1,3 DIPALMITATE DERIVATIVE; 1,2,3 TRIHYDROXY 1,3 DISTEARATE DERIVATIVE; ACYLGLYCEROL DERIVATIVE; CARBOXYL GROUP; GLYCEROL; MEFENAMIC ACID; PRODRUG; UNCLASSIFIED DRUG;

EID: 14244255978     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (16)
  • 1
    • 33947295869 scopus 로고
    • An efficient synthesis of symmetrical 1,3-diglycerides
    • Bently PH, McCrae W (1969) An efficient synthesis of symmetrical 1,3-diglycerides. J Org Chem 35: 2082-2083
    • (1969) J Org Chem , vol.35 , pp. 2082-2083
    • Bently, P.H.1    McCrae, W.2
  • 2
    • 0030879768 scopus 로고    scopus 로고
    • Retrometabolic approaches for drug design and targeting
    • Bodor N (1997) Retrometabolic approaches for drug design and targeting. Pharmazie 52: 491-494.
    • (1997) Pharmazie , vol.52 , pp. 491-494
    • Bodor, N.1
  • 3
    • 0018667262 scopus 로고
    • The role of direct contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats
    • Cioli V, Putzolu S, Rossi V, Corza BP, Corradino C (1979) The role of direct contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats. Toxicol Appl Pharmacol 50: 283-289
    • (1979) Toxicol Appl Pharmacol , vol.50 , pp. 283-289
    • Cioli, V.1    Putzolu, S.2    Rossi, V.3    Corza, B.P.4    Corradino, C.5
  • 4
    • 0029803908 scopus 로고    scopus 로고
    • Synthesis and antiinflammatory activity of niflumic acid lipophilic prodrugs in brain edema
    • El Kihel L, Bourass J, Richomme P, Petit JY, Letoumeux Y (1996) Synthesis and antiinflammatory activity of niflumic acid lipophilic prodrugs in brain edema. Arzneim-Forsch/Drug Res. 46: 1040-1044.
    • (1996) Arzneim-Forsch/Drug Res , vol.46 , pp. 1040-1044
    • El Kihel, L.1    Bourass, J.2    Richomme, P.3    Petit, J.Y.4    Letoumeux, Y.5
  • 6
    • 76549245881 scopus 로고
    • The pattern of emptying of the human stomach
    • Hunt JN, Spurrel WR (1951) The pattern of emptying of the human stomach. J Physiol 113: 157-168.
    • (1951) J Physiol , vol.113 , pp. 157-168
    • Hunt, J.N.1    Spurrel, W.R.2
  • 7
    • 0035093162 scopus 로고    scopus 로고
    • Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3- nitrate, a putative prodrug of ibuprofen and glycerol-1-nitrate
    • Ingram MJ, Humphrey AM, Powell MW, Chris R (2001) Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3-nitrate, a putative prodrug of ibuprofen and glycerol-1-nitrate. J Pharm Pharmacol 53: 345-351.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 345-351
    • Ingram, M.J.1    Humphrey, A.M.2    Powell, M.W.3    Chris, R.4
  • 8
    • 0032710426 scopus 로고    scopus 로고
    • Cyclic amide derivatives as potential prodrugs II, N-hydroxy methyl succinimide/isatin esters of some NSAIDS as prodrugs with an improved therapeutic index
    • Mahfouz N, Omar FA, Aboul-Fadl T (1999) Cyclic amide derivatives as potential prodrugs II, N- hydroxy methyl succinimide/isatin esters of some NSAIDS as prodrugs with an improved therapeutic index. Eur J Med Chem 34: 551-562.
    • (1999) Eur J Med Chem , vol.34 , pp. 551-562
    • Mahfouz, N.1    Omar, F.A.2    Aboul-Fadl, T.3
  • 9
    • 0035093162 scopus 로고    scopus 로고
    • Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3- nitrate, a putative prodrug of ibuprofen and glycerol-1-nitrate
    • Matthew JI, Humphrey A, Moynihan MW, Powell CR (2001) Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3-nitrate, a putative prodrug of ibuprofen and glycerol-1-nitrate. J Pharm Pharmacol 53: 345-350.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 345-350
    • Matthew, J.I.1    Humphrey, A.2    Moynihan, M.W.3    Powell, C.R.4
  • 10
    • 0026557715 scopus 로고
    • Ester and amide prodrugs of ibuprofen and naproxen: Synthesis, anti-inflammatory activity and gastrointestinal toxicity
    • Shanbhag VR, Harpalani A, Dick RM (1992) Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity and gastrointestinal toxicity, J Pharm Sci 81: 149-154.
    • (1992) J Pharm Sci , vol.81 , pp. 149-154
    • Shanbhag, V.R.1    Harpalani, A.2    Dick, R.M.3
  • 11
    • 84873776176 scopus 로고
    • A method for evaluating both non-narcotic and narcotic analgesics
    • Siegmund E, Cadmus R, Lu G (1957) A method for evaluating both non-narcotic and narcotic analgesics. Proc Soc Exp Biol Med 95: 729-731.
    • (1957) Proc Soc Exp Biol Med , vol.95 , pp. 729-731
    • Siegmund, E.1    Cadmus, R.2    Lu, G.3
  • 12
    • 0037212569 scopus 로고    scopus 로고
    • Simultaneous determination of arylpropionic acidic non-steroidal anti-inflammatory drugs in pharmaceutical formulations and human plasma by HPLC with UV detection
    • Sun Y, Takaba K, Kido H, Nakashima MN, Nakashima K (2003) Simultaneous determination of arylpropionic acidic non-steroidal anti-inflammatory drugs in pharmaceutical formulations and human plasma by HPLC with UV detection, J Pharm Biomed Anal 30: 1611-1619.
    • (2003) J Pharm Biomed Anal , vol.30 , pp. 1611-1619
    • Sun, Y.1    Takaba, K.2    Kido, H.3    Nakashima, M.N.4    Nakashima, K.5
  • 15
    • 0035994891 scopus 로고    scopus 로고
    • Synthesis and properties of a naproxen polymeric prodrug
    • Wang LF, Chiang HN, Chem WB (2002) Synthesis and properties of a naproxen polymeric prodrug. J Pharm Pharmacol 54: 1129-1135.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 1129-1135
    • Wang, L.F.1    Chiang, H.N.2    Chem, W.B.3
  • 16
    • 67249094291 scopus 로고
    • Carrageenan-induced edema in hind paw of rats as an assay for anti-inflammatory drug
    • Winter C, Risley E, Nuss G (1962) Carrageenan-induced edema in hind paw of rats as an assay for anti-inflammatory drug. Proc Soc Exp Biol Med 111: 544-547.
    • (1962) Proc Soc Exp Biol Med , vol.111 , pp. 544-547
    • Winter, C.1    Risley, E.2    Nuss, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.