Synthesis and evaluation of the anti-inflammatory effects of niflumic acid lipophilic prodrugs in brain edema

Arzneimittel-Forschung/Drug Research

Volumn 46, Issue 11, 1996, Pages 1040-1044

  El Kihel, Laïla ^a   Bourass, Jilali ^a   Richomme, Pascal ^b   Petit, Jean Yves ^c   Letourneux, Yves ^a  

^a UNIVERSITÉ DE LA ROCHELLE   (France)

^b UNIVERSITÉ D'ANGERS   (France)

^c UNIVERSITÉ DE NANTES   (France)

Author keywords

anti inflammatories, blood brain barrier, lipophilic prodrugs, non steroidal; CAS 4394 00 7; niflumic acid; Nifluril

Indexed keywords

CHOLESTEROL; DEXAMETHASONE; DIACYLGLYCEROL; HEXADECANOL; NEW DRUG; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE A2; PRODRUG; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN LEVEL; CONTROLLED STUDY; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LIPOPHILICITY; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROSTAGLANDIN SYNTHESIS; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DINOPROSTONE; MALE; NIFLUMIC ACID; PHOSPHOLIPASES A; PRODRUGS; RATS; RATS, INBRED STRAINS;

EID: 0029803908     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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