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Volumn 34, Issue 7-8, 1999, Pages 551-562

Cyclic amide derivatives as potential prodrugs II: N- hydroxymethylsuccinimide- / isatin esters of some NSAIDs as prodrugs with an improved therapeutic index

Author keywords

In vitro stability; Lipophilicity; N hydroxy methylisatin (HMIS); N hydroxymethylsuccinimide (HMSI); NSAI prodrugs; Ulcerogenicity

Indexed keywords

AMIDE; N HYDROXYMETHYLSUCCINIMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PRODRUG; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0032710426     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(00)80025-2     Document Type: Article
Times cited : (56)

References (26)
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    • Vane J.R. Nature. 231:1971;232-235.
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    • Vane, J.R.1
  • 17
    • 24544469216 scopus 로고
    • Leo A.J. Chem. Rev. 93:1993;1281-1306.
    • (1993) Chem. Rev. , vol.93 , pp. 1281-1306
    • Leo, A.J.1
  • 25
    • 0344108393 scopus 로고    scopus 로고
    • Brit. Patent 1, 220, 447, (1971); through ref. 11
    • Borrows E.T., Johnson J.M., Brit. Patent 1, 220, 447, (1971); through ref. 11.
    • Borrows, E.T.1    Johnson, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.