Activation and attenuation of apoptosis of CD4+ T cells following in vivo exposure to two common environmental toxicants, trichloroacetaldehyde hydrate and trichloroacetic acid

Journal of Autoimmunity

Volumn 23, Issue 3, 2004, Pages 211-220

  Blossom, Sarah J ^a   Pumford, Neil R ^b   Gilbert, Kathleen M ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS   (United States)

Author keywords

Apoptosis; CD4+ T cells; Environmental toxicant; Trichloroacetaldehyde hydrate; Trichloroacetic acid

Indexed keywords

CD4 ANTIGEN; CHLORAL HYDRATE; DRINKING WATER; GAMMA INTERFERON; PADGEM PROTEIN; TRICHLOROACETIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ATTENUATION; AUTOIMMUNE DISEASE; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNOREGULATION; INTERFERON PRODUCTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 14244254310     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaut.2004.06.007     Document Type: Article

References (48)

1. I. Kimber, and R.J. Dearman Immunologic basis for autoimmunity and the potential influences of xenobiotics Toxicol Lett 127 2002 77 81
2. X.S. He, A.A. Ansari, and M.E. Gershwin Xenobiotic considerations for the development of autoimmune liver diseases: bad genes and bad luck Rev Environ Health 16 2001 191 202
3. A.T.S.D.R. Toxicological profile for trichloroethylene. Update Draft for Public Comments. U.S. Department of Health and Human Services: Agency for Toxic Substances and Disease Registry; 1995.
4. V.S. Byers, A.S. Levin, D.M. Ozonoff, and R.W. Baldwin Association between clinical symptoms and lymphocyte abnormalities in a population with chronic domestic exposure to industrial solvent-contaminated domestic water supply and a high incidence of leukaemia Cancer Immunol Immunother 27 1988 77 81
5. P.A. Waller, D. Clauw, T. Cupps, J.S. Metcalf, R.M. Silver, and E.C. Leroy Fasciitis (not scleroderma) following prolonged exposure to an organic solvent (trichloroethylene) J Rheumatol 21 1994 1567 1570
6. D.S. Yanez, M. Moran, P. Unamuno, and M. Armijo Silica and trichloroethylene-induced progressive systemic sclerosis Dermatology 184 1992 98 102
7. B.L. Hansen, and H. Isager [A scleroderma-resembling disease - exposure to trichloroethylene and trichloroethane, is there a causal connection?] Ugeskr Laeger 150 1988 805
8. E.M. Saihan, J.L. Burton, and K.W. Heaton A new syndrome with pigmentation, scleroderma, gynaecomastia, Raynaud's phenomenon and peripheral neuropathy Br J Dermatol 99 1978 437 440
9. H. Flindt-Hansen, and H. Isager Scleroderma after occupational exposure to trichloroethylene and trichloroethane Acta Derm Venereol 67 1987 263 264
10. K.H. Kilburn, and R.H. Warshaw Prevalence of symptoms of systemic lupus erythematosus (SLE) and of fluorescent antinuclear antibodies associated with chronic exposure to trichloroethylene and other chemicals in well water Environ Res 57 1992 1 9
11. P.J. Nietert, S.E. Sutherland, R.M. Silver, J.P. Pandey, R.G. Knapp, and D.G. Hoel Is occupational organic solvent exposure a risk factor for scleroderma? Arthritis Rheum 41 1998 1111 1118
12. M.F. Khan, B.S. Kaphalia, B.S. Prabhakar, M.F. Kanz, and G.A. Ansari Trichloroethene-induced autoimmune response in female MRL+/+ mice Toxicol Appl Pharmacol 134 1995 155 160
13. D.H. Kono, M.S. Park, A. Szydlik, K.M. Haraldsson, J.D. Kuan, and D.L. Pearson Resistance to xenobiotic-induced autoimmunity maps to chromosome 1 J Immunol 167 2001 2396 2403
14. K.M. Pollard, D.L. Pearson, P. Hultman, T.N. Deane, U. Lindh, and D.H. Kono Xenobiotic acceleration of idiopathic systemic autoimmunity in lupus-prone bxsb mice Environ Health Perspect 109 2001 27 33
15. B.H. Hahn Animal Models of systemic lupus erythematosus F.P. Quismorio J.R. Klinenberg Dubois' lupus erythematosus 1993 Lea & Febiger Philadelphia 157 177
16. J.M. Griffin, K.M. Gilbert, L.W. Lamps, and N.R. Pumford CD4(+) T-cell activation and induction of autoimmune hepatitis following trichloroethylene treatment in MRL+/+ mice Toxicol Sci 57 2000 345 352
17. J.M. Griffin, K.M. Gilbert, and N.R. Pumford Inhibition of CYP2E1 reverses CD4+ T-cell alterations in trichloroethylene-treated MRL+/+ mice Toxicol Sci 54 2000 384 389
18. J.M. Griffin, S.J. Blossom, S.K. Jackson, K.M. Gilbert, and N.R. Pumford Trichloroethylene accelerates an autoimmune response by Th1 T cell activation in MRL +/+ mice Immunopharmacology 46 1999 123 137
19. F.P. Guengerich, and T. Shimada Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes Chem Res Toxicol 4 1991 391 407
20. I.W. Davidson, and R.P. Beliles Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics Drug Metab Rev 23 1991 493 599
21. K.M. Gilbert, A.B. Whitlow, and N.R. Pumford Environmental contaminant and disinfection by-product trichloroacetaldehyde stimulates T cells in vitro, Int Immunopharmacology 4 2004 25 36
22. S. Blossom, and K.M. Gilbert Antibody production in autoimmune BXSB mice. I. CD40L-expressing B cells need fewer signals for polyclonal antibody synthesis Clin Exp Immunol 118 1999 147 153
23. M. Ahmadzadeh, S.F. Hussain, and D.L. Farber Heterogeneity of the memory CD4 T cell response: persisting effectors and resting memory T cells J Immunol 166 2001 926 935
24. C.C. Chao, R. Jensen, and M.O. Dailey Mechanisms of L-selectin regulation by activated T cells J Immunol 159 1997 1686 1694
25. V.A. Boussiotis, G.J. Freeman, J.G. Gribben, J. Daley, G. Gray, and L.M. Nadler Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation Proc Natl Acad Sci 90 1993 11059 11063
26. J.G. Monroe, and J.C. Cambier Level of mIa expression on mitogen-stimulated murine B lymphocytes is dependent on position in cell cycle J Immunol 130 1983 626 631
27. D. Balomenos, R. Rumold, and A.N. Theofilopoulos Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice J Clin Invest 101 1998 364 371
28. F. Le Deist, J.F. Emile, F. Rieux-Laucat, M. Benkerrou, I. Roberts, and N. Brousse Clinical, immunological, and pathological consequences of Fas-deficient conditions Lancet 348 1996 719 723
29. M.L. Watson, J.K. Rao, G.S. Gilkeson, P. Ruiz, E.M. Eicher, and D.S. Pisetsky Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci J Exp Med 176 1992 1645 1656
30. K.M. Gilbert, J.M. Griffin, and N.R. Pumford Trichloroethylene activates CD4+ T cells: potential role in an autoimmune response Drug Metab Rev 31 1999 901 916
31. D. Laderach, S. Koutouzov, J.F. Bach, and A.M. Yamamoto Concomitant early appearance of anti-ribonucleoprotein and anti-nucleosome antibodies in lupus prone mice J Autoimmun 20 2003 161 170
32. Autoimmune Diseases Coordinating Committee. 2002. Autoimmune Disease Research Plan. National Institutes of Health, pp. 1-61.
33. F.B. Daniel, A.B. DeAngelo, J.A. Stober, G.R. Olson, and N.P. Page Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse Fundam Appl Toxicol 19 1992 159 168
34. S.L. Herren-Freund, M.A. Pereira, M.D. Khoury, and G. Olson The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver Toxicol Appl Pharmacol 90 1987 183 189
35. Y. Adachi, M. Inaba, A. Sugihara, M. Koshiji, K. Sugiura, and Y. Amoh Effects of administration of monoclonal antibodies (anti-CD4 or anti-CD8) on the development of autoimmune diseases in (NZW × BXSB)F1 mice Immunobiology 198 1998 451 464
36. M. Goldman, P. Druet, and E. Gleichmann TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity Immunol Today 12 1991 223 227
37. J. Rossert, L. Pelletier, R. Pasquier, and P. Druet Autoreactive T cells in mercury-induced autoimmunity. Demonstration by limiting dilution analysis Eur J Immunol 18 1988 1761 1766
38. L.M. Bradley, G.G. Atkins, and S.L. Swain Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor J Immunol 148 1992 324 331
39. A. Cerwenka, T.M. Morgan, and R.W. Dutton Naive, effector, and memory CD8 T cells in protection against pulmonary influenza virus infection: homing properties rather than initial frequencies are crucial J Immunol 163 1999 5535 5543
40. C. Haas, B. Ryffel, and M. Le Hir IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice J Immunol 158 1997 5484 5491
41. X. Fan, and R.P. Wuthrich Upregulation of lymphoid and renal interferon-gamma mRNA in autoimmune MRL-Fas(lpr) mice with lupus nephritis Inflammation 21 1997 105 112
42. R.P. Wuthrich, A.M. Jevnikar, F. Takei, L.H. Glimcher, and V.E. Kelley Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis Am J Pathol 136 1990 441 450
43. A. Kretz-Rommel, and R.L. Rubin Persistence of autoreactive T cell drive is required to elicit anti-chromatin antibodies in a murine model of drug-induced lupus J Immunol 162 1999 813 820
44. M.J. McCabe Jr., M.J. Whitekus, J. Hyun, K.G. Eckles, G. McCollum, and A.J. Rosenspire Inorganic mercury attenuates CD95-mediated apoptosis by interfering with formation of the death inducing signaling complex Toxicol Appl Pharmacol 190 2003 146 156
45. F.A. Beland, T.C. Schmitt, N.F. Fullerton, and J.F. Young Metabolism of chloral hydrate in mice and rats after single and multiple doses J Toxicol Environ Health 154 1998 209 226
46. R.R. Abbas, C.S. Seckel, J.K. Kidney, and J.W. Fisher Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice Drug Metab Dispos 24 1996 1340 1346
47. D.D. Breimer Clinical pharmacokinetics of hypnotics Clin Pharmacokinet 2 1977 93 109
48. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Chloral and chloral hydrate vol. 63 1995 International Agency for Research in Cancer p. 245-69