Alkaline proteinase inhibitor of Pseudomonas aeruginosa. A mutational and molecular dynamics study of the role of N-terminal residues in the inhibition of Pseudomonas alkaline proteinase

Journal of Biological Chemistry

Volumn 278, Issue 28, 2003, Pages 25952-25957

  Feltzer, Rhona E ^a   Trent, John O ^a   Gray, Robert D ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYME INHIBITION; RATE CONSTANTS; X RAY CRYSTALLOGRAPHY; ZINC;

ALKALINE PROTEINASE INHIBITOR;

PROTEINS;

ALKALINE PROTEINASE; ARGININE; ASPARTIC ACID; CARBOXYL GROUP; GLUTAMINE; MUTANT PROTEIN; PROTEINASE INHIBITOR; SERINE; TRYPTOPHAN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; COMPLEX FORMATION; DISSOCIATION CONSTANT; ENZYME BINDING; ENZYME INHIBITION; ENZYME SUBSTRATE; GENE MUTATION; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PSEUDOMONAS AERUGINOSA; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; CATALYTIC DOMAIN; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; IONS; KINETICS; MODELS, MOLECULAR; MUTATION; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SERINE ENDOPEPTIDASES; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0037830594     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212691200     Document Type: Article

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