Mechanical stress and glucose concentration modulate glucose transport in cultured rat podocytes

Nephrology Dialysis Transplantation

Volumn 20, Issue 2, 2005, Pages 306-311

  Lewko, Barbara ^a,b   Bryl, Ewa ^a   Witkowski, Jacek M ^a   Latawiec, Elzbieta ^a   Angielski, Stefan ^a,b   Stepinski, Jan ^a,b  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Cultured podocytes; GLUT2; GLUT4; High glucose; Mechanical stress

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DIABETIC NEPHROPATHY; FEMALE; FLOW CYTOMETRY; GLUCOSE TRANSPORT; INCUBATION TIME; MECHANICAL STRESS; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ANIMALS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; GLUCOSE TRANSPORTER TYPE 4; KIDNEY GLOMERULUS; KINETICS; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; RATS; RATS, WISTAR; STRESS, MECHANICAL;

EID: 14044278076     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/gfh612     Document Type: Article

References (20)

1. Mundel P, Kriz W. Structure and function of podocytes: an update. Anat Embryol 1995; 192: 385-397
2. Pavenstaedt H, Kriz W, Kretzler M. Cell biology of the glomerular podocyte. Physiol Rev 2003; 83: 253-307
3. Gassler N, Elger M, Kranzlin B et al. Podocyte injury underlies the progression of focal segmental glomerulosclerosis in the fa/fa Zucker rat. Kidney Int 2001; 60: 106-116
4. van Det NF, Verhagen NA, Tamsma JT et al. Regulation of glomerular epithelial cell production of fibronectin and transforming growth factor-beta by high glucose, not by angiotensin II. Diabetes 1997; 46: 834-840
5. Yard BA, Kahlert S, Engelleiter R et al. Decreased glomerular expression of agrin in diabetic nephropathy and podocytes cultured in high glucose medium. Exp Nephrol 2001; 9: 214-222
6. Pagtalunan ME, Miller PL, Jumping-Eagle S et al. Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest 1997; 99: 342-348
7. Thlemann J, Ploug T, Hellsten Y Galbo H. Effect of tension on contraction-induced glucose transport in rat skeletal muscle. Am J Physiol 1999; 277: E208-E214
8. Fischereder M, Schroeppel B, Wiese P. et al. Regulation of glucose transporters in human peritoneal mesothelial cells. J Nephrol 2003; 16: 103-109
9. Alpert E, Gruzman A, Totary H, Kaiser N, Reich R, Sasson S. A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: role of glucose and 12-hydroxyeicosatetraenoic acid. Biochem J 2002; 362: 413-422
10. Lewko B, Bryl E., Witkowski, JM et al. Characterization of glucose uptake by cultured rat podocytes. Kidney Blood Press Res 2004; 28: 1-7
11. Golos M, Lewko B, Bryl E et al. Effect of angiotensin II on ANP-dependent guanylyl cyclase activity in cultured mouse and rat podocytes. Kidney Blood Press Res 2002; 25: 296-302
12. Bergmeyer HU. Methods of Enzymatic Analysis. Academic Press, New York; 1974: 480-481
13. Zor T, Selinger Z. Linearization of the Bradford protein assay increases its sensitivity. Theoretical and experimental studies. Anal Biochem 1996; 236: 302-308
14. Durvasula RV, Petermann AT, Hiromura K et al. Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int 2004; 63: e30-39
15. Gnudi L, Viberti GC, Raij L et al. GLUT-1 overexpression. Link between hemodynamic and metabolic factors in glomerular injury? Hypertension. 2003; 42: 19-24
16. Maher F, Davies-Hill TM, Simpson IA.. Substrate specifity and kinetic parameters of GLUT3 in rat cerebellar granule neurons. Biochem J 1996; 315: 827-831
17. Li C, Xu Q. Mechanical stress-initiated signal transductions in vascular smooth muscle cells. Cell Signal 2000; 12: 435-445
18. Cortes P, Yee J. Potentiation of glucose-mediated glomerular injury by mechanical strain. Clin Exp Pharmacol Physiol 2002; 29: 149-152
19. Forbes JM, Bonnet F, Russo LM et al. Modulation of nephrin in the diabetic kidney: association with systemic hypertension and increasing albuminuria. J Hypertens 2002; 20: 985-992
20. Zatz R, Meyer TW, Rennke HG, Brenner BM. Predominance of hemodynamic rather than metabolic factors in the pathogenesis of diabetic glomerulopathy. Proc Natl Acad. Sci USA 1985; 82: 5963-5967