Roles of conserved proline and glycosyltransferase motifs of EmbC in biosynthesis of lipoarabinomannan

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 5651-5663

  Berg, Stefan ^a   Starbuck, James ^a   Torrelles, Jordi B ^a,b   Vissa, Varalakshmi D ^a   Crick, Dean C ^a   Chatterjee, Delphi ^a   Brennan, Patrick J ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CELLS; ENZYMES; PROTEINS; REDUCTION; SUGARS;

ETHAMBUTOL (EMB); GLYCOSYLTRANSFERASE MOTIFS M; LIPOARABINOMANNAN (LAM); POLYMERASES;

ENZYME KINETICS;

ARABINOGALACTAN; ARABINOSE DERIVATIVE; BACTERIAL POLYSACCHARIDE; BACTERIAL POLYSACCHARIDE COPOLYMERASE; BETA DEXTRO ARABINOFURANOSYL 1 MONOPHOSPHORYLDECAPRENOL; DEXTRO ARABINAN; DEXTRO ARABINOFURANOSE; ETHAMBUTOL; GENE PRODUCT; GLYCOSYLTRANSFERASE; LIPOARABINOMANNAN; MUTANT PROTEIN; PROLINE; PROTEIN DERIVATIVE; PROTEIN EMBA; PROTEIN EMBB; PROTEIN EMBC; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL WALL; CARBOHYDRATE ANALYSIS; CELL STRUCTURE; CONTROLLED STUDY; DONOR; DRUG BINDING SITE; GENETIC CONSERVATION; GENETIC LINKAGE; LIPOGENESIS; MYCOBACTERIUM SMEGMATIS; NONHUMAN; OBSERVATION; POINT MUTATION; PRECURSOR; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; CARBOHYDRATES; CHROMATOGRAPHY, GAS; CONSERVED SEQUENCE; GENES, BACTERIAL; GLYCOSYLTRANSFERASES; LIPOPOLYSACCHARIDES; METHYLATION; MOLECULAR SEQUENCE DATA; MUTATION; MYCOBACTERIUM SMEGMATIS; PROLINE; PROTEIN CONFORMATION; SEQUENCE ANALYSIS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS;

EID: 14044270954     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411418200     Document Type: Article

References (49)

1. McNeil, M., Daffe, M., and Brennan, P. J. (1990) J. Biol. Chem. 265, 18200-18206
2. McNeil, M., Daffe, M., and Brennan, P. J. (1991) J. Biol. Chem. 266, 13217-13223
3. Brennan, P. J. (2003) Tuberculosis 83, 91-97
4. Constant, P., Perez, E., Malaga, W., Laneelle, M. A., Saurel, O., Daffe, M., and Guilhot, C. (2002) J. Biol. Chem. 277, 38148-38158
5. Telenti, A., Philipp, W. J., Sreevatsan, S., Bernasconi, C., Stockbauer, K. E., Wieles, B., Musser, J. M., and Jacobs, W. R., Jr. (1997) Nat. Med. 3, 567-570
6. Ramaswamy, S. V., Amin, A. G., Goksel, S., Stager, C. E., Dou, S. J., El Sahly, H., Moghazeh, S. L., Kreiswirth, B. N., and Musser, J. M. (2000) Antimicrob. Agents Chemother. 44, 326-336
7. Dover, L. G., Cerdeno-Tarraga, A. M., Pallen, M. J., Parkhill, J., and Besra, G. S. (2004) FEMS Microbiol. Rev. 28, 225-250
8. Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B. J., Gaigalat, L., Goesmann, A., Hartmann, M., Huthmacher, K., Kramer, R., Linke, B., McHardy, A. C., Meyer, F., Mockel, B., Pfefferle, W., Puhler, A., Rey, D. A., Ruckert, C., Rupp, O., Sahm, H., Wendisch, V. F., Wiegrabe, I., and Tauch, A. (2003) J. Biotechnol. 104, 5-25
9. Escuyer, V. E., Lety, M. A., Torrelles, J. B., Khoo, K. H., Tang, J. B., Rithner, C. D., Frehel, C., McNeil, M. R., Brennan, P. J., and Chatterjee, D. (2001) J. Biol. Chem. 276, 48854-48862
10. Zhang, N., Torrelles, J. B., McNeil, M. R., Escuyer, V. E., Khoo, K. H., Brennan, P. J., and Chatterjee, D. (2003) Mol. Microbiol. 50, 69-76
11. Belanger, A. E., Besra, G. S., Ford, M. E., Mikusova, K., Belisle, J. T., Brennan, P. J., and Inamine, J. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11919-11924
12. Daniels, C., and Morona, R. (1999) Mol. Microbiol. 34, 181-194
13. Becker, A., and Puhler, A. (1998) J. Bacteriol. 180, 395-399
14. Liu, J., and Mushegian, A. (2003) Protein Sci. 12, 1418-1431
15. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402
16. Huang, X., and Miller, W. (1991) Adv. Appl. Math. 12, 337-357
17. Cuff, J. A., and Barton, G. J. (2000) Proteins 40, 502-511
18. Hofmann, K., and Stoffel, W. (1993) Biol. Chem. Hoppe-Seyler 374, 166
19. Krogh, A., Larsson, B., von Heijne, G., and Sonnhammer, E. L. (2001) J. Mol. Biol. 305, 567-580
20. Stover, C. K., de la Cruz, V. F., Fuerst, T. R., Burlein, J. E., Benson, L. A., Bennett, L. T., Bansal, G. P., Young, J. F., Lee, M. H., Hatfull, G. F., Snapper, S. B., Barletta, R. G., Jacobs, W. R., and Bloom, B. R. (1991) Nature 351, 456-460
21. Atlas, R. M. (1997) in Handbook of Microbial Media (Parks, L. C., ed) 2nd Ed., pp. 1225-1226, CRC Press, Inc., Boca Raton, FL
22. Snapper, S. B., Melton, R. E., Mustafa, S., Kieser, T., and Jacobs, W. R., Jr. (1990) Mol. Microbiol. 4, 1911-1919
23. Khoo, K. H., Douglas, E., Azadi, P., Inamine, J. M., Besra, G. S., Mikusova, K., Brennan, P. J., and Chatterjee, D. (1996) J. Biol. Chem. 271, 28682-28690
24. Mikusova, K., Slayden, R. A., Besra, G. S., and Brennan, P. J. (1995) Antimicrob. Agents Chemother. 39, 2484-2489
25. Prinzis, S., Chatterjee, D., and Brennan, P. J. (1993) J. Gen. Microbiol. 139, 2649-2658
26. Kaur, D., Lowary, T. L., Vissa, V. D., Crick, D. C., and Brennan, P. J. (2002) Microbiology 148, 3049-3057
27. Tuncer, M., and Ball, A. S. (2003) Folia Microbiol. 48, 168-172
28. McNeil, M., Chatterjee, D., Hunter, S. W., and Brennan, P. J. (1989) Methods Enzymol. 179, 215-242
29. Dell, A., Reason, A. J., Khoo, K. H., Panico, M., McDowell, R. A., and Morris, H. R. (1994) Methods Enzymol. 230, 108-132
30. Sweet, D. P., Shapiro, R. H., and Albersheim, P. (1975) Carbohydr. Res. 40, 217-225
31. McNeil, M. R., Robuck, K. G., Harter, M., and Brennan, P. J. (1994) Glycobiology 4, 165-173
32. Chatterjee, D., and Khoo, K H. (1998) Glycobiology 8, 113-120
33. Melen, K., Krogh, A., and von Heijne, G. (2003) J. Mol. Biol. 327, 735-744
34. von Heijne, G. (1989) Nature 341, 456-458
35. Bastin, D. A., Stevenson, G., Brown, P. K., Haase, A., and Reeves, P. R. (1993) Mol. Microbiol. 7, 725-734
36. Morona, R., Van den, B. L., and Daniels, C. (2000) Microbiology 146, 1-4
37. Oriol, R., Martinez-Duncker, I., Chantret, I., Mollicone, R., and Codogno, P. (2002) Mol. Biol. Evol. 19, 1451-1463
38. Jackson, M., Crick, D. C., and Brennan, P. J. (2000) J. Biol. Chem. 275, 30092-30099
39. Xin, Y., Lee, R. E., Scherman, M. S., Khoo, K. H., Besra, G. S., Brennan, P. J., and McNeil, M. (1997) Biochim. Biophys. Acta 1335, 231-234
40. Stokes, R. W., and Speert, D. P. (1995) J. Immunol. 155, 1361-1369
41. Underbill, D. M., Ozinsky, A., Smith, K. D., and Aderem, A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14459-14463
42. Chan, J., Fan, X. D., Hunter, S. W., Brennan, P. J., and Bloom, B. R. (1991) Infect. Immun. 59, 1755-1761
43. Wolucka, B. A., McNeil, M. R., de Hoffmann, E., Chojnacki, T., and Brennan, P. J. (1994) J. Biol. Chem. 269, 23328-23335
44. Unligil, U. M., and Rini, J. M. (2000) Curr. Opin. Struct. Biol. 10, 510-517
45. Maeda, Y., Watanabe, R., Harris, C. L., Hong, Y., Ohishi, K., Kinoshita, K., and Kinoshita, T. (2001) EMBO J. 20, 250-261
46. Sreevatsan, S., Stockbauer, K. E., Pan, X., Kreiswirth, B. N., Moghazeh, S. L., Jacobs, W. R., Jr., Telenti, A., and Musser, J. M. (1997) Antimicrob. Agents Chemother. 41, 1677-1681
47. Paulsen, I. T., Beness, A. M., and Saier, M. H., Jr. (1997) Microbiology 143, 2685-2699
48. Raetz, C. R., and Whitfield, C. (2002) Annu. Rev. Biochem. 71, 635-700
49. Morona, R., Van den, B. L., and Manning, P. A. (1995) J. Bacteriol. 177, 1059-1068