Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocket

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 5884-5891

  Krishnamurthy, Ganga ^a   Vikram, Rajagopal ^a   Singh, Sudha B ^a   Patel, Nitin ^a   Agarwal, Shruti ^a   Mukhopadhyay, Gauranga ^b   Basu, Sandip K ^a   Mukhopadhyay, Amitabha ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BINDING ENERGY; BIOLOGICAL MEMBRANES; ENZYMES; GENES; IMMUNOLOGY;

HB ENDOCYTOSIS; HEXOKINASE (HK); IMMUNOLOCALIZATION;

HEMOGLOBIN;

ADENOSINE TRIPHOSPHATE; HEMOGLOBIN RECEPTOR; HEXOKINASE; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENDOCYTOSIS; FLAGELLUM; GENE OVEREXPRESSION; GENETIC TRANSFECTION; LEISHMANIA DONOVANI; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PURIFICATION; PROTEIN SYNTHESIS INHIBITION; RECEPTOR BINDING; SEQUENCE ANALYSIS;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; FLAGELLA; HEMOGLOBINS; HEXOKINASE; KINETICS; LEISHMANIA DONOVANI; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

LEISHMANIA DONOVANI;

EID: 14044263048     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411845200     Document Type: Article

References (42)

1. Chang, K. P. (1983) Int. Rev. Cytol. Suppl. 14, 267-305
2. Sah, J. F., Ito, H., Kolli, B. K., Peterson, D. A., Sassa, S., and Chang, K. P. (2002) J. Biol. Chem. 277, 14902-14909
3. Chang, K. P., and Trager, W. (1974) Science 183, 531-532
4. Chen, C., Sparling, P. F., Lewis, L. A., Dyer, D. W., and Elkins, C. (1996) Infect. Immun. 64, 5008-5014
5. Jin, H., Ren, Z., Pozsgay, J. H., Elkins, C., Whitby, P. W., Morton, D. J., and Still, T. L. (1996) Infect. Immun. 64, 3134-3141
6. Wilson, M. E., and Britigan, B. E. (1998) Parasitol. Today 14, 348-353
7. Wandersman, C., and Stojiljkovic, I. (2000) Curr.. Opin. Microbiol. 3, 215-220
8. Sengupta, S., Tripathi, J., Tandon, R., Raje, M., Roy, R. P., Basu, S. K., and Mukhopadhyay, A. (1999) J. Biol. Chem. 274, 2758-2765
9. Singh, S. B., Tandon, R., Krishnamurthy, G., Vikram, R., Sharma, N., Basu, S. K., and Mukhopadhyay, A. (2003) EMBO J. 22, 5712-5722
10. Bastin, P., Stephan, A., Raper, J., Saint-Remy, J. M., Opperdoes, F. R., and Courtoy, P. J. (1996) Mol. Biochem. Parasitol. 76, 43-56
11. Liu, J., Qiao, X., Du, D., and Lee, M. G. (2000) J. Biol. Chem. 275, 12032-12040
12. Voyiatzaki, C. S., and Soteriadou, K. P. (1992) J. Biol. Chem. 267, 9112-9117
13. Clayton, C., Hausler, T., and Blattner, J. (1995) Microbiol. Rev. 59, 325-344
14. Overkamp, D., Mohammed, A. S., Cartledge, C., and London, J. (1988) J. Immunol. 9, 51-68
15. Mukherjee, K., Siddiqi, S. A., Hashim, S., Raje, M., Basu, S. K., and Mukhopadhyay, A. (2000) J. Cell Biol. 148, 741-743
16. Roy, J. C. (1932) Ind. J. Med. Res. 20, 355-367
17. Mazumder, S., Mukherjee, T., Ghosh, J., Ray, M., and Bhaduri, A. (1992) J. Biol. Chem. 267, 18440-18446
18. Mukherjee, K., Parashuraman, S., Raje, M., and Mukhopadhyay, A. (2001) J. Biol. Chem. 276, 23607-23615
19. Gruenberg, J., Griffiths, G., and Howell, K. E. (1989) J. Cell Biol. 108, 1301-1316
20. Bordier, C. (1981) J. Biol. Chem. 256, 1604-1607
21. Wilson, M., Sanejouand, Y. H., Perie, J., Hannaert, V., and Opperdoes, F. (2002) Chem. Biol. 9, 839-947
22. Sinha, K. M., Ghosh, M., Das, I., and Dutta, A. K. (1999) Biochem. J. 339, 667-673
23. Ha, D. S., Schwarz, J. K., Turco, S. J., and Beverley, S. M. (1996) Mol. Biochem. Parasitol. 77, 57-64
24. Kapler, G. M., Coburn, C. M., and Beverley, S. M. (1990) Mol. Cell. Biol. 10, 1084-1094
25. Fraenkel, D. G., and Horecker, B. L. (1964) J. Biol. Chem. 239, 2765-2771
26. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
27. Sutton, R. E., and Boothroyd, J. C. (1986) Cell 47, 527-535
28. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680
29. Schirch, D. M., and Wilson, J. E. (1987) Arch. Biochem. Biophys. 254, 385-396
30. Bork, P., Sander, C., and Valencia, A. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7290-7294
31. Caceres, A. J., Portillo, R., Acosta, H., Rosales, D., Quinones, W., Avilan, L., Salazar, L., Dubourdieu, M., Michels, P. A. M., and Concepcion, J. L. (2003) Mol. Biochem. Parasitol. 126, 251-262
32. Overath, P., Stierhof, Y., and Weise, M. (1997) Trends Cell Biol. 7, 27-33
33. Frommer, W. B., Schulze, W. X., and Lalonde, S. (2003) Science 300, 261-263
34. Gozalbo, D., Gil-Navarro, I., Azorin, I., Renau-Piqueras, J., Martinez, J. P., and Gil, M. L. (1998) Infect. Immun. 66, 2052-2059
35. Modun, B., Morrissey, J., and Williams, P. (2000) Trends Microbiol. 8, 231-237
36. Robbins, A. R., Ward, R. D., and Oliver, C. (1995) J. Cell Biol. 130, 1093-1104
37. Tisdale, E. J. (2002) J. Biol. Chem. 277, 3334-3341
38. Leyton, L., and Saling, P. (1989) Cell 57, 1123-1130
39. Kalab, P., Visconti, P., Leclerc, P., and Kopf, G. S. (1994) J. Biol. Chem. 269, 3810-3817
40. Moore, B., Zhou, L., Rolland, F., Hall, Q., Cheng, W. H., Liu, Y. X., Hwang, I., Jones, T., and Sheen, J. (2003) Science 300, 332-336
41. Wiese, A., Groner, F., Sonnewald, U., Deppner, H., Lerchl, J., Hebbeker, U., Flugge, U., and Weber, A. (1999) FEBS Lett. 461, 13-18
42. Holmes, E. W., Malone, J. I., Winegrad, A. I., and Oski, F. A. (1967) Science 156, 646-648