Glucocorticoid-induced changes in the global gene expression of lens epithelial cells

Journal of Ocular Pharmacology and Therapeutics

Volumn 21, Issue 1, 2005, Pages 11-27

  James, Eric R ^a   Fresco, Victor M ^a   Robertson, Lorie L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; DIMETHYL SULFOXIDE; GLUCOCORTICOID; TRANSCRIPTION FACTOR;

ARTICLE; CELL ADHESION; CELL CYCLE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; DNA HYBRIDIZATION; DNA MICROARRAY; DOWN REGULATION; DRUG EFFECT; EPITHELIUM CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LENS EPITHELIUM; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; UPREGULATION;

EID: 14044257231     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2005.21.11     Document Type: Article

References (48)

1. Leske, M.C., Chylack, L.T. Jr., He, Q., et al. Incidence and progression of cortical and posterior subcapsular opacities: The longitudinal study of cataract. LSC Group Ophthalmol. 104:1987-1993, 1997.
2. Klein, B.E., Klein, R., and Lee, K.E. Incidence of age-related cataract: The Beaver Dam Eye Study. Arch Ophthalmol. 116:219-225, 1998.
3. McCarty, C.A., Nanjan, M.B., and Taylor, H.R. Attributable risk estimates for cataract to prioritize medical and public health action. Invest. Ophthalmol. Vis. Sci. 41:3720-3725, 2000.
4. Hiller, R., Sperduto, R.D., and Reed, G.F., et al. Serum lipids and age-related lens opacities: A longitudinal investigation: The Framingham Studies. Ophthalmology 110:578-583, 2003.
5. Costagliola, C., Cati-Giovannelli, B., Piccirillio, A., et al. Cataracts associated with long-term topical steroids. Brit. J. Dermatol. 120:472-473, 1989.
6. Renfro, L., and Snow, J.S. Ocular effects of topical and systemic steroids. Dermatol. Clin. 10:505-512, 1992.
7. Veenstra, D.L., Best, J.H., and Hornberger, J., et al. Incidence and long-term cost of steroid-related side-effects after renal transplantation. Am. J. Kidney Dis. 33:829-839, 1999.
8. Urban, R.C. Jr., and Cotlier, E. Corticosteroid-induced cataracts. Surv. Ophthalmol. 31:102-110, 1986.
9. Dickerson, J.E. Jr., Dotzel, E., and Clark, A.F. Steroid-induced cataract: New perspective from in vitro and lens culture studies. Exp. Eye Res. 65:507-516, 1997.
10. Riccardi, C., Bruscoli, S., Ayroldi, E., et al. GILZ, a glucocorticoid hormone-induced gene, modulates T lymphocytes activation and death through interaction with NF-kB. Adv. Exp. Med. Biol. 495:31-39, 2001.
11. Tuckermann, J.P., Reichardt, H.M., Arribas, R., et al. The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin. J. Cell Biol. 147:1365-1370, 1999.
12. James, E.R., Robertson, L., Ehlert, E., et al. Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells. Invest. Ophthalmol. Vis. Sci. 44:5269-5276, 2003.
13. Riccardi, C., Zollo, O., Nocentini, G., et al. Glucocorticoid hormones in the regulation of cell death. Therapie 55:165-169, 2000.
14. Siebler, T., Robson, H., Shalet, S.M., et al. Dexamethasone inhibits and thyroid hormone promotes differentiation of mouse chondrogenic ATDC5 cells. Bone 31:457-464, 2002.
15. Greenberg, A.K., Hu, J., Basu, S., et al. Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators. Am. J. Respir. Cell. Mol. Biol. 27:320-328, 2002.
16. Kolbus, A., Blazques-Domingo, M., Carotta, S., et al. Cooperative signaling between cytokine receptors and the glucocorticoid receptor in expansion of erythroid progenitors: Molecular analysis by expression profiling. Blood 102:3136-3146, 2003.
17. Jeon, J.W., Lee, S.J., Kim, J.B., et al. Cellular proliferative effect of dexamethasone in immortalized trabecular meshwork cell (TM5) line. Yonsei Med. J. 44:299-306, 2003.
18. Lyu, J., Kim, J.A., Chung, S.K., et al. Alteration of cadherin in dexamethasone-induced cataract organ-cultured rat lens. Invest. Ophthalmol. Vis. Sci. 44:2034-2040, 2003.
19. Li, C., and Wong, H.W. DNA-chip analyzer (dChip). Parmigiani, G., Garrett, E.S., Irizarry, R., and Zeger, S.L., eds. The Analysis of Gene Expression Data: Methods and Software, New York: Springer, 120-141, 2003.
20. Li, C., and Wong, H.W. Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection. Proc. Natl. Acad. Sci. 98:31-36, 2001.
21. Liu, G., Loraine, A.E., Shigeta, R., et al. NetAffx: Affymetrix probesets and annotations. Nucleic Acids Res. 31:82-86, 2003.
22. Schaaf, M.J., and Cidlowski, J.A. Molecular determinants of glucocorticoid receptor mobility in living cells: The importance of ligand affinity. Mol. Cell. Biol. 23:1922-1934, 2003.
23. Newton, R. Molecular mechanisms of glucocorticoid action: What is important? Thorax 55:603-613, 2000.
24. Jenkins, B.D., Pullen, C.B., and Darimont, B.D. Novel glucocorticoid receptor coactivator effector mechanisms. Trends Endocrinol. Metab. 12:122-126, 2001.
25. Leung, D.Y., and Bloom, J.W. Update on glucocorticoid action and resistance. J. Allergy Clin. Immunol. 111:3-22, 2003.
26. Aurrekoetxea-Hernandez, K., and Buetti, E. Transforming growth factor beta enhances the glucocorticoid response of the mouse mammary tumor virus promoter through Smad and GA-binding proteins. J. Virol. 78:2201-2211, 2004.
27. Wu, W., Chaudhuri, S., Brickley, D.R., et al. Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells. Cancer Res. 64:1757-1764, 2004.
28. Naray-Fejes-Toth, A., Fejes-Toth, G., Volk, K.A., et al. SGK is a primary glucocorticoid-induced gene in the human. J. Steroid Biochem. Mol. Biol. 75:51-56, 2000.
29. D'Adamio, F., Zollo, O., Moraca, R., et al. A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death. Immunity 7:803-812, 1997.
30. Wang, X., Garcia, C.M., Shu, Y.-B., et al. Expression of crystallins in the mammalian lens epithelium, Association for Research in Vision and Ophthalmology (ARVO), Ft. Lauderdale, FL, 2004; abs 3961.
31. Badea, T., Niculescu, F., Soane, L., et al. RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase. J. Biol. Chem. 277:502-508, 2002.
32. Shvarts, A., Brummelkamp, T.R., Scheeren, F., et al. A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling. Genes Dev. 16:681-686, 2002.
33. Engelbrecht, Y., de Wet, H., Horsch, K., et al. Glucocorticoids induce rapid up regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines. Endocrinology 144:412-422, 2003.
34. Liao, Q., Guo, J., Kleeff, J., et al. Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells. Gastroenterology 124:1830-1845, 2003.
35. Gitler, A.D., and Epstein, J.A. Regulating heart development: The role of Nf1. Cell Cycle 2:96-98, 2003.
36. Donovan, S., See, W., Bonifas, J., et al. Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells. Cancer Cell 2:507-514, 2002.
37. Landolt, R.M., Vaughan, L., Winterhalter, K.H., et al. Versican is selectively expressed in embryonic tissues that act as barriers to neural crest cell migration and axon outgrowth. Development 121:2303-2312, 1995.
38. Henderson, D.J., and Copp, A.J. Versican expression is associated with chamber specification, septation, and valvulogenesis in the developing mouse heart. Circ. Res. 83:523-532, 1998.
39. Chen, J.S., Coustan-Smith, E., Suzuki, T., et al. Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia. Blood 97:2115-2120, 2001.
40. Walker, J., and Rigley, K. Gene expression profiling in human peripheral blood mononuclear cells using high-density, filter-based cDNA microarrays. J. Immunol. Meth. 239:167-179, 2000.
41. Andley, U.P., Patel, H.C., Xi, J.-H., et al. Identification of genes responsive to UV-A radiation in human lens epithelial cells using complementary DNA microarrays. Photochem. Photobiol. 80:61-71, 2004.
42. Hawse, J.R., Hejtmancik, J.F., Huang, Q., et al. Identification and functional clustering of global gene expression differences between human age-related cataract and clear lenses. Mol. Vis. 9:515-537, 2003. 〈http://www.molvis.org/molvis/v9/a65/〉.
43. Segev, F., Mor, O., Segec, A., et al. Downregulation of gene expression in the aging lens: A possible contributory factor in senile cataract. Eye 19:80-85, 2005. epub: 23 April http://nature.com/cgi-taf/Dynapage.taf?File/ege/ Journal/v19/nl/full/6701423a.html
44. Wormstone, I.M., Liu, C.S., Rakic, J.M., et al. Human lens epithelial cell proliferation in a protein-free medium. Invest. Ophthalmol. Vis. Sci. 38:396-404, 1997.
45. Huang, J.X., Feldmeier, M., Shui, Y.B., et al. Evaluation of fibroblast growth factor signaling during lens fiber cell differentiation. Invest. Ophthalmol. Vis. Sci. 44:680-690, 2003.
46. Alemany, J., Girbau, M., Bassas, L., et al. Insulin receptors and insulin-like growth factor I receptors are functional during organogenesis of the lens. Mol. Cell. Endocrinol. 74:155-162, 1990.
47. Belecky-Adams, T.L., Adler, R., and Beebe, D.C. Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development; 129:3795-3802, 2002.
48. Lowe, C., Gray, D.H., and Reid, I.R. Serum blocks the osteolytic effect of cortisol in neonatal mouse calvaria. Calcif. Tissue Int. 50:189-192, 1992.