Crystal structure and novel recognition motif of Rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: Structural insights for recognition specificity and catalysis

Journal of Molecular Biology

Volumn 305, Issue 1, 2001, Pages 95-107

  Han, Seungil ^a   Arvai, Andrew S ^a   Clancy, Sheila B ^a   Tainer, John A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

ADP ribosyltransferase; C3 exoenzyme; Catalytic mechanism; Clostridium botulinum; NAD

Indexed keywords

ADENOSINE DIPHOSPHATE; BACTERIAL ENZYME; BACTERIAL TOXIN; CLOSTRIDIUM BOTULINUM C3 EXOENZYME; GLUTAMIC ACID; GLUTAMINE; GUANOSINE TRIPHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHENYLALANINE; RHO FACTOR; UNCLASSIFIED DRUG; VEGETATIVE INSECTICIDAL PROTEIN 2;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CLOSTRIDIUM BOTULINUM; CONTROLLED STUDY; CYTOSKELETON; DEPOLYMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MOTIF; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TARGET CELL;

EID: 0035808303     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4292     Document Type: Article

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