A new function for nonsense-mediated mRNA-decay factors

Trends in Genetics

Volumn 21, Issue 3, 2005, Pages 143-148

  Wilkinson, Miles F ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGO NASHI HOMOLOG PROTEIN; MESSENGER RNA; NONSENSE MEDIATED MRNA DECAY FACTOR; PROTEIN; PROTEIN RNPS1; PROTEIN Y14; UNCLASSIFIED DRUG; UP FRAMESHIFT 1 PROTEIN; UP FRAMESHIFT 2 PROTEIN; UP FRAMESHIFT 3B PROTEIN;

CELL PROTECTION; EXON; GENE MUTATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; QUALITY CONTROL; REVIEW; RNA DEGRADATION; RNA SPLICING; RNA TRANSLATION; STOP CODON; TRANSLATION INITIATION;

MAGO; MAMMALIA;

EID: 13944249950     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2005.01.007     Document Type: Article

References (49)

1. P.A. Frischmeyer, and H.C. Dietz Nonsense-mediated mRNA decay in health and disease Hum. Mol. Genet. 8 1999 1893 1900
2. M.R. Culbertson RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer Trends Genet. 15 1999 74 80
3. J.A. Holbrook Nonsense-mediated decay approaches the clinic Nat. Genet. 36 2004 801 808
4. M.S. Carter A splicing-dependent regulatory mechanism that detects translation signals EMBO J. 15 1996 5965 5975
5. S. Li, and M.F. Wilkinson Nonsense surveillance in lymphocytes? Immunity 8 1998 135 141
6. M. Morrison Smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans Proc. Natl. Acad. Sci. U. S. A. 94 1997 9782 9785
7. Q.M. Mitrovich, and P. Anderson Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans Genes Dev. 14 2000 2173 2184
8. B.P. Lewis Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans Proc. Natl. Acad. Sci. U. S. A. 100 2003 189 192
9. J.T. Mendell Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise Nat. Genet. 36 2004 1073 1078
10. L.E. Maquat Nonsense-mediated mRNA decay: Splicing, translation and mrnp dynamics Nat. Rev. Mol. Cell Biol. 5 2004 89 99
11. M.C. Wollerton Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay Mol. Cell 13 2004 91 100
12. C.I. Gonzalez Nonsense-mediated mRNA decay in Saccharomyces cerevisiae Gene 274 2001 15 25
13. T.O. Tange The ever-increasing complexities of the exon junction complex Curr. Opin. Cell Biol. 16 2004 279 284
14. J. Callis Introns increase gene expression in cultured maize cells Genes Dev. 1 1987 1183 1200
15. H. Le Hir How introns influence and enhance eukaryotic gene expression Trends Biochem. Sci. 28 2003 215 220
16. M. Braddock Intron-less RNA injected into the nucleus of Xenopus oocytes accesses a regulated translation control pathway Nucleic Acids Res. 22 1994 5255 5264
17. K. Matsumoto Nuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA EMBO J. 17 1998 2107 2121
18. A. Nott Splicing enhances translation in mammalian cells: an additional function of the exon junction complex Genes Dev. 18 2004 210 222
19. H.L. Wiegand Exon junction complexes mediate the enhancing effect of splicing on mRNA expression Proc. Natl. Acad. Sci. U. S. A. 100 2003 11327 11332
20. J. Lykke-Andersen Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1 Science 293 2001 1836 1839
21. A.B. Maderazo Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p Mol. Cell. Biol. 20 2000 4591 4603
22. W. Wang The role of upf proteins in modulating the translation read-through of nonsense-containing transcripts EMBO J. 20 2001 880 890
23. K.M. Keeling Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae RNA 10 2004 691 703
24. J.W. Harger, and J.D. Dinman Evidence against a direct role for the upf proteins in frameshifting or nonsense codon readthrough RNA 10 2004 1721 1729
25. J.T. Mendell Separable roles for RENT1/hUPF1 in altered splicing and decay of nonsense transcripts Science 298 2002 419 422
26. T. Maniatis, and R. Reed An extensive network of coupling among gene expression machines Nature 416 2002 499 506
27. N.J. Proudfoot Integrating mRNA processing with transcription Cell 108 2002 501 512
28. S. Barbaux Donor splice-site mutations in WT1 are responsible for Frasier syndrome Nat. Genet. 17 1997 467 470
29. G.E. Crawford Assembly of the dystrophin-associated protein complex does not require the dystrophin cooh-terminal domain J. Cell Biol. 150 2000 1399 1410
30. D.M. Bedwell Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line Nat. Med. 3 1997 1280 1284
31. K.M. Keeling Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-l-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation Hum. Mol. Genet. 10 2001 291 299
32. B. Klamt Frasier syndrome is caused by defective alternative splicing of wt1 leading to an altered ratio of WT1 +/-KTS splice isoforms Hum. Mol. Genet. 7 1998 709 714
33. T.P. Kerr Long mutant dystrophins and variable phenotypes: evasion of nonsense-mediated decay? Hum. Genet. 109 2001 402 407
34. S.A. Pitts HMRE11: Genomic structure and a null mutation identified in a transcript protected from nonsense-mediated mRNA decay Hum. Mol. Genet. 10 2001 1155 1162
35. F. Usuki Inhibition of nonsense-mediated mRNA decay rescues the phenotype in Ullrich's disease Ann. Neurol. 55 2004 740 744
36. P. Mitchell, and D. Tollervey An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3′→5′ degradation Mol. Cell 11 2003 1405 1413
37. A.B. Maderazo Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution Mol. Cell. Biol. 23 2003 842 851
38. F. Lejeune eIF4G is required for the pioneer round of translation in mammalian cells Nat. Struct. Mol. Biol. 11 2004 992 1000
39. A. Buzina, and M.J. Shulman Infrequent translation of a nonsense codon is sufficient to decrease mRNA level Mol. Biol. Cell 10 1999 515 524
40. J.P. Gudikote, and M.F. Wilkinson T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts EMBO J. 21 2002 125 134
41. D. Gatfield Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways EMBO J. 22 2003 3960 3970
42. D. Muhlrad, and R. Parker Recognition of yeast mRNAs as 'nonsense containing' leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decapping Mol. Biol. Cell 10 1999 3971 3978
43. F. He Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5′ to 3′ mRNA decay pathways in yeast Mol. Cell 12 2003 1439 1452
44. M.J. Lelivelt, and M.R. Culbertson Yeast upf proteins required for RNA surveillance affect global expression of the yeast transcriptome Mol. Cell. Biol. 19 1999 6710 6719
45. K. Inoue Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations Nat. Genet. 36 2004 361 369
46. S.M. Medghalchi RENT1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability Hum. Mol. Genet. 10 2001 99 105
47. H. Le Hir Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions Genes Dev. 14 2000 1098 1108
48. M.F. Wilkinson, and A.B. Shyu RNA surveillance by nuclear scanning? Nat. Cell Biol. 4 2002 E144 E147
49. J. Wang Boundary-independent polar nonsense-mediated decay EMBO Rep. 3 2002 274 279