Lipase-catalyzed resolution of (2R*,3S*)- and (2R*,3R*)-3-methyl-3-phenyl-2-aziridinemethanol at low temperatures and determination of the absolute configurations of the four stereoisomers

Journal of Organic Chemistry

Volumn 70, Issue 4, 2005, Pages 1369-1375

  Sakai, Takashi ^a   Liu, Yu ^a   Ohta, Hiroshi ^a   Korenaga, Toshinobu ^a   Ema, Tadashi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; CATALYSIS; DERIVATIVES; ESTERS; METHANOL; PHENOLS; REACTION KINETICS; X RAY ANALYSIS;

METHYLATION; NEBER REACTION; OXIME TOSYLATE; STEREOISOMERS;

ISOMERS;

3 METHYL 3 PHENYL 2 AZIRIDINEMETHANOL; ACETIC ACID; AZIRIDINE DERIVATIVE; AZIRINE DERIVATIVE; METHANOL; N 2 (6 METHOXY 2 NAPHTHYL)PROPANOYL DERIVATIVE; NAPHTHYL GROUP; OXIME; PROPANOL; TERT BUTYL 3 PHENYL 2H AZIRINE 2 CARBOXYLATE; TOLUENESULFONIC ACID DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ARTICLE; CATALYSIS; CYCLIZATION; HYDROLYSIS; LOW TEMPERATURE; METHYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOISOMERISM; X RAY ANALYSIS;

AZIRIDINES; CATALYSIS; LIPASE; METHANOL; MOLECULAR STRUCTURE; PYRIDINES; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TEMPERATURE; THIAZOLES;

EID: 13844306889     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048243n     Document Type: Article

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