Loss of FHIT expression in squamous cell carcinoma and premalignant lesions of the larynx

Annals of Otology, Rhinology and Laryngology

Volumn 114, Issue 2, 2005, Pages 127-131

  Yuge, Tadashi ^a,b   Shibahara, Junji ^a,c   Nibu, Kenichi ^a,d   Tayama, Niro ^a,b   Kondo, Kenji ^a,c   Sugasawa, Masashi ^a,c  

^a Intl Medical Center of Japan ^*

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Dysplasia; FHIT; Head and neck squamous cell carcinoma; Larynx

Indexed keywords

FRAGILE HISTIDINE TRIAD PROTEIN;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CHROMOSOME 3P; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DYSPLASIA; EARLY DIAGNOSIS; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INACTIVATION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LARYNGEAL BIOPSY; LARYNX TUMOR; MALE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; TISSUE SPECIFICITY; TUMOR SUPPRESSOR GENE;

EID: 13844289311     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348940511400208     Document Type: Article

References (20)

1. Jones MH, Nakamura Y. Deletion mapping of chromosome 3p in female genital malignancies using microsatellite polymorphisms. Oncogene 1992;7:1631-4.
2. Ohta M, Inoue H, Cotticelli MG, et al. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 1996;84:587-97.
3. Ji L, Fang B, Yen N, Fong K, Minna JD, Roth JA. Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression. Cancer Res 1999;59:3333-9.
4. Pace HC, Garrison PN, Robinson AK, et al. Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc Natl Acad Sci U S A 1998;95:5484-9.
5. Sozzi G, Huebner K, Croce CM. FHIT in human cancer. Adv Cancer Res 1998;74:141-66.
6. Lima CD, Klein MG, Hendrickson WA. Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science 1997;278:286-90.
7. Yoshino K, Enomoto T, Nakamura T, et al. FHIT alterations in cancerous and non-cancerous cervical epithelium. Int J Cancer 2000;85:6-13.
8. Sozzi G, Pastorino U, Moiraghi L, et al. Loss of FHIT function in lung cancer and preinvasive bronchial lesions. Cancer Res 1998;58:5032-7.
9. Tanimoto K, Hayashi S, Tsuchiya E, et al. Abnormalities of the FHIT gene in human oral carcinogenesis. Br J Cancer 2000;82:838-43.
10. Virgilio L, Shuster M, Gollin SM, et al. FHIT gene alterations in head and neck squamous cell carcinomas. Proc Natl Acad Sci U S A 1996;93:9770-5.
11. Greenspan DL, Connolly DC, Wu R, et al. Loss of FHIT expression in cervical carcinoma cell lines and primary tumors. Cancer Res 1997;57:4692-8.
12. Sozzi G, Veronese ML, Negrini M, et al. The FHIT gene 3p14.2 is abnormal in lung cancer. Cell 1996;85:17-26.
13. Hayashi S, Tanimoto K, Hajiro-Nakanishi K, et al. Abnormal FHIT transcripts in human breast carcinomas: a clinicopathological and epidemiological analysis of 61 Japanese cases. Cancer Res 1997;57:1981-5.
14. Sozzi G, Tornielli S, Tagliabue E, et al. Absence of Fhit protein in primary lung tumor and cell lines with FHIT gene abnormalities. Cancer Res 1997;57:5207-12.
15. Lee JI, Soria JC, Hassan K, et al. Loss of Fhit expression is a predictor of poor outcome in tongue cancer. Cancer Res 2001;61:837-41.
16. Gotte K, Hadaczek P, Coy JF, et al. Fhit expression is absent or reduced in a subset of primary head and neck cancer. Anticancer Res 2000;20:1057-60.
17. Blackwell KE, Fu YS, Calcaterra TC. Laryngeal dysplasia. A clinicopathologic study. Cancer 1995;75:457-63.
18. Hellquist H, Lundgren J, Olofsson J. Hyperplasia, keratosis, dysplasia and carcinoma in situ of the vocal cords - a follow-up study. Clin Otolaryngol 1982;7:11-27.
19. Silvestri F, Bussani R, Pavletic N, Mannone T, Bosatra A. From epithelial dysplasia to squamous carcinoma of the head and neck region: evolutive and prognostic histopathological markers. Acta Otolaryngol Suppl (Stockh) 1997(suppl 527):49-51.
20. van Heerden WFP, Swart TJP, van Heerden MB, et al. Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas. J Oral Pathol Med 1999;28:433-7.