Structure of the carboxypeptidase Y inhibitor IC in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction

Journal of Molecular Biology

Volumn 346, Issue 5, 2005, Pages 1323-1334

  Mima, Joji ^a   Hayashida, Minoru ^a,c   Fujii, Tomomi ^a   Narita, Yusuke ^a   Hayashi, Rikimaru ^b   Ueda, Mitsuyoshi ^a   Hata, Yasuo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c RIKEN HARIMA INSTITUTE   (Japan)

Author keywords

CPY; Crystal structure; IC; PEBP; Proteinase inhibition

Indexed keywords

CARBOXYPEPTIDASE C; COGNATE PROTEINASE; ENZYME INHIBITOR; MUTANT PROTEIN; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PHOSPHOLIPID; PROTEIN DERIVATIVE; PROTEINASE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GENETIC CONSERVATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 13844281614     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.12.051     Document Type: Article

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