Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2

Nature Structural Biology

Volumn 7, Issue 4, 2000, Pages 322-328

  Reverter, David ^a,b   Fernández Catalán, Carlos ^b   Baumgartner, Roland ^b   Pfänder, Ruth ^b   Huber, Robert ^b   Bode, Wolfram ^b   Vendrell, Josep ^a   Holak, Tad A ^b   Avilés, Francesc X ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE A; ENZYME INHIBITOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; LEECH; MOLECULAR EVOLUTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOTECHNOLOGY; CARBOXYPEPTIDASES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; DRUG DESIGN; ENZYME PRECURSORS; EVOLUTION, MOLECULAR; HUMANS; LEECHES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT PROTEINS; PLIABILITY; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

HIRUDINIDA; HIRUDO MEDICINALIS; SOLANUM TUBEROSUM;

EID: 0343569968     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/74092     Document Type: Article

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