-
1
-
-
13844285384
-
Effect of oltipraz on phase I and phase II xenobiotic metabolizing enzymes
-
Bao,Y. and Fenwick,R. (eds) Marcel Dekker, New York, NY
-
Langouet,S., Morel,F. and Guillouzo,A. (2004) Effect of oltipraz on phase I and phase II xenobiotic metabolizing enzymes. In Bao,Y. and Fenwick,R. (eds) Phytochemicals in Health and Disease. Marcel Dekker, New York, NY, pp. 311-329.
-
(2004)
Phytochemicals in Health and Disease
, pp. 311-329
-
-
Langouet, S.1
Morel, F.2
Guillouzo, A.3
-
2
-
-
0035451390
-
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones
-
Kwak,M.K., Egner,P.A., Dolan,P.M., Ramos-Gomez,M., Groopman,J.D., Itoh,K., Yamamoto,M. and Kensler,T.W. (2001) Role of phase 2 enzyme induction in chemoprotection by dithiolethiones. Mutat. Res. 480/481, 305-315.
-
(2001)
Mutat. Res.
, vol.480-481
, pp. 305-315
-
-
Kwak, M.K.1
Egner, P.A.2
Dolan, P.M.3
Ramos-Gomez, M.4
Groopman, J.D.5
Itoh, K.6
Yamamoto, M.7
Kensler, T.W.8
-
3
-
-
0034014663
-
Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives and sulforaphane
-
Langouet,S., Furge,L.L., Kerriguy,N., Nakaimura,K., Guillouzo,A. and Guengerich,F.P. (2000) Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives and sulforaphane. Chem. Res. Toxicol., 13, 245-252.
-
(2000)
Chem. Res. Toxicol.
, vol.13
, pp. 245-252
-
-
Langouet, S.1
Furge, L.L.2
Kerriguy, N.3
Nakaimura, K.4
Guillouzo, A.5
Guengerich, F.P.6
-
4
-
-
0027497708
-
Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene and dithiolethiones
-
Morel,F., Fardel,O., Meyer,D.J. et al. (1993) Preferential increase of glutathione S-transferase class alpha transcripts in cultured human hepatocytes by phenobarbital, 3-methylcholanthrene and dithiolethiones. Cancer Res., 53, 231-234.
-
(1993)
Cancer Res.
, vol.53
, pp. 231-234
-
-
Morel, F.1
Fardel, O.2
Meyer, D.J.3
-
5
-
-
0031768584
-
Endotoxin suppresses the oltipraz-mediated induction of major hepatic glutathione transferases and cytochromes P450 in the rat
-
Maheo,K., Morel,F., Antras-Ferry,J., Langouet,S., Desmots,F., Corcos,L. and Guillouzo,A. (1998) Endotoxin suppresses the oltipraz-mediated induction of major hepatic glutathione transferases and cytochromes P450 in the rat. Hepatology, 28, 1655-1662.
-
(1998)
Hepatology
, vol.28
, pp. 1655-1662
-
-
Maheo, K.1
Morel, F.2
Antras-Ferry, J.3
Langouet, S.4
Desmots, F.5
Corcos, L.6
Guillouzo, A.7
-
6
-
-
0031950013
-
Identification of dithiolethione-inducible gene-1 as a leukotriene B4 12-hydroxydehydrogenase: Implications for chemoprevention
-
Primiano,T., Li,Y., Kensler,T.W., Trush,M.A. and Sutter,T.R. (1998) Identification of dithiolethione-inducible gene-1 as a leukotriene B4 12-hydroxydehydrogenase: implications for chemoprevention. Carcinogenesis, 19, 999-1005.
-
(1998)
Carcinogenesis
, vol.19
, pp. 999-1005
-
-
Primiano, T.1
Li, Y.2
Kensler, T.W.3
Trush, M.A.4
Sutter, T.R.5
-
7
-
-
0036021113
-
The drug efflux pump MRP2: Regulation of expression in physiopathological situations and by endogenous and exogenous compounds
-
Payen,L., Sparfel,L., Courtois,A., Vernhet,L., Guillouzo,A. and Fardel,O. (2002) The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds. Cell Biol. Toxicol., 18, 221-233.
-
(2002)
Cell Biol. Toxicol.
, vol.18
, pp. 221-233
-
-
Payen, L.1
Sparfel, L.2
Courtois, A.3
Vernhet, L.4
Guillouzo, A.5
Fardel, O.6
-
8
-
-
0031426029
-
Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP213 in rat liver and rat hepatocytes in culture
-
Langouet,S., Maheo,K., Berthou,F., Morel,F., Lagadic-Gossmann,D., Glaise,D., Coles,B., Ketterer,B. and Guillouzo,A. (1997) Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP213 in rat liver and rat hepatocytes in culture. Carcinogenesis, 18, 1343-1349.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1343-1349
-
-
Langouet, S.1
Maheo, K.2
Berthou, F.3
Morel, F.4
Lagadic-Gossmann, D.5
Glaise, D.6
Coles, B.7
Ketterer, B.8
Guillouzo, A.9
-
9
-
-
0031410750
-
Oltipraz stimulates the transcription of the manganese superoxide dismutase gene in rat hepatocytes
-
Antras-Ferry,J., Maheo,K., Chevanne,M., Dubos,M.P., Morel,F., Guillouzo,A., Cillard,P. and Cillard,J. (1997) Oltipraz stimulates the transcription of the manganese superoxide dismutase gene in rat hepatocytes. Carcinogenesis, 18, 2113-2117.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2113-2117
-
-
Antras-Ferry, J.1
Maheo, K.2
Chevanne, M.3
Dubos, M.P.4
Morel, F.5
Guillouzo, A.6
Cillard, P.7
Cillard, J.8
-
10
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
Kwak,M.K., Wakabayashi,N., Itoh,K., Motohashi,H., Yamamoto,M. and Kensler,T.W. (2003) Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J. Biol. Chem., 278, 8135-8145.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
11
-
-
0036702273
-
Strategies for chemoprevention of liver cancer
-
Kensler,T.W., Egner,P.A., Wang,J.B. et al. (2002) Strategies for chemoprevention of liver cancer. Eur. J. Cancer. Prev. 11 (suppl. 2), S58-S64.
-
(2002)
Eur. J. Cancer. Prev.
, vol.11
, Issue.SUPPL. 2
-
-
Kensler, T.W.1
Egner, P.A.2
Wang, J.B.3
-
12
-
-
0031394646
-
Oltipraz chemoprevention trial in Qidong, Jiangsu Province, People's Republic of China
-
Zhang,B.C., Zhu,Y.R., Wang,J.B. et al. (1997) Oltipraz chemoprevention trial in Qidong, Jiangsu Province, People's Republic of China. J. Cell. Biochem., 28-29 (suppl.), 166-173.
-
(1997)
J. Cell. Biochem.
, vol.28-29
, Issue.SUPPL.
, pp. 166-173
-
-
Zhang, B.C.1
Zhu, Y.R.2
Wang, J.B.3
-
13
-
-
0033577057
-
Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China
-
Wang,J.S., Shen,X., He,X. et al. (1999) Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China. J. Natl Cancer Inst. 91, 347-354.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 347-354
-
-
Wang, J.S.1
Shen, X.2
He, X.3
-
14
-
-
0028832190
-
Pharmacokinetics and pharmacodynamics of oltipraz as a chemopreventive agent
-
Gupta,E., Olopade,O.I., Ratain,M.J., Mick,R., Baker,T.M., Berezin,F.K., Benson,A.B.,III and Dolan,M.E. (1995) Pharmacokinetics and pharmacodynamics of oltipraz as a chemopreventive agent. Clin. Cancer Res., 1, 1133-1138.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1133-1138
-
-
Gupta, E.1
Olopade, O.I.2
Ratain, M.J.3
Mick, R.4
Baker, T.M.5
Berezin, F.K.6
Benson III, A.B.7
Dolan, M.E.8
-
15
-
-
0038683154
-
Role of the AP-1 element and redox factor-1 (Ref-1) in mediating transcriptional induction of DT-diaphorase gene expression by oltipraz: A target for chemoprevention
-
Yao,K.S. and O'Dwyer,P.J. (2003) Role of the AP-1 element and redox factor-1 (Ref-1) in mediating transcriptional induction of DT-diaphorase gene expression by oltipraz: a target for chemoprevention. Biochem. Pharmacol., 66, 15-23.
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 15-23
-
-
Yao, K.S.1
O'Dwyer, P.J.2
-
16
-
-
0029830816
-
Induction of hepatic heme oxygenase-1 and, ferritin in rats by cancer chemopreventive dithiolethiones
-
Primiano,T., Kensler,T.W., Kuppusamy,P., Zweier,J.L. and Sutter,T.R. (1996) Induction of hepatic heme oxygenase-1 and, ferritin in rats by cancer chemopreventive dithiolethiones. Carcinogenesis, 17, 2291-2296.
-
(1996)
Carcinogenesis
, vol.17
, pp. 2291-2296
-
-
Primiano, T.1
Kensler, T.W.2
Kuppusamy, P.3
Zweier, J.L.4
Sutter, T.R.5
-
17
-
-
0142181031
-
Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor
-
Cherrington,N.J., Slitt,A.L., Maher,J.M., Zhang,X.X., Zhang,J., Huang,W., Wan,Y.J., Moore,D.D. and Klaassen,C.D. (2003) Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor. Drug Metab. Dispos. 31, 1315-1319.
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 1315-1319
-
-
Cherrington, N.J.1
Slitt, A.L.2
Maher, J.M.3
Zhang, X.X.4
Zhang, J.5
Huang, W.6
Wan, Y.J.7
Moore, D.D.8
Klaassen, C.D.9
-
18
-
-
0037025336
-
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent
-
Le Ferrec,E., Lagadic-Gossmann,D., Rauch,C., Bardiau,C., Maheo,K., Massiere,F., Le Vee,M., Guillouzo,A. and Morel,F. (2002) Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent. J. Biol. Chem., 277, 24780-24787.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24780-24787
-
-
Le Ferrec, E.1
Lagadic-Gossmann, D.2
Rauch, C.3
Bardiau, C.4
Maheo, K.5
Massiere, F.6
Le Vee, M.7
Guillouzo, A.8
Morel, F.9
-
19
-
-
0028865229
-
Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture
-
Langouet,S., Coles,B., Morel,F., Becquemont,L., Beaune,P., Guengerich,F.P., Ketterer,B. and Guillouzo,A. (1995) Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture. Cancer Res., 55, 5574-5579.
-
(1995)
Cancer Res.
, vol.55
, pp. 5574-5579
-
-
Langouet, S.1
Coles, B.2
Morel, F.3
Becquemont, L.4
Beaune, P.5
Guengerich, F.P.6
Ketterer, B.7
Guillouzo, A.8
-
20
-
-
0035011152
-
In vivo inhibition of human CYP1A2 activity by oltipraz
-
Sofowora,G.G., Choo,E.F., Mayo,G., Shyr,Y. and Wilkinson,G.R. (2001) In vivo inhibition of human CYP1A2 activity by oltipraz. Cancer Chemother. Pharmacol., 47, 505-510.
-
(2001)
Cancer Chemother. Pharmacol.
, vol.47
, pp. 505-510
-
-
Sofowora, G.G.1
Choo, E.F.2
Mayo, G.3
Shyr, Y.4
Wilkinson, G.R.5
-
21
-
-
0031047586
-
Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: Hepatoprotective effects
-
Kim,N.D., Kwak,M.K. and Kim,S.G. (1997) Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects. Biochem. Pharmacol. 53, 261-269.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 261-269
-
-
Kim, N.D.1
Kwak, M.K.2
Kim, S.G.3
-
22
-
-
0027192867
-
Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes
-
Elegbede,J.A., Maltzman,T.H., Elson,C.E. and Gould,M.N. (1993) Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes. Carcinogenesis, 14, 1221-1223.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1221-1223
-
-
Elegbede, J.A.1
Maltzman, T.H.2
Elson, C.E.3
Gould, M.N.4
-
23
-
-
0038796599
-
Induction of NAD(P)H quinone: Oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats
-
Begleiter,A., Sivananthan,K., Curphey,T.J. and Bird,R.P. (2003) Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats. Cancer Epidemiol. Biomarkers Prev., 12, 566-572.
-
(2003)
Cancer Epidemiol. Biomarkers Prev.
, vol.12
, pp. 566-572
-
-
Begleiter, A.1
Sivananthan, K.2
Curphey, T.J.3
Bird, R.P.4
-
24
-
-
0030868098
-
Chemoprevention by inducers of carcinogen detoxication enzymes
-
Kensler,T.W. (1997) Chemoprevention by inducers of carcinogen detoxication enzymes. Environ. Health Perspect., 105 (suppl. 4), 965-970.
-
(1997)
Environ. Health Perspect.
, vol.105
, Issue.SUPPL. 4
, pp. 965-970
-
-
Kensler, T.W.1
-
25
-
-
9544250360
-
Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz
-
O'Dwyer,P.J., Szarka,C.E., Yao,K.S. et al. (1996) Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz. J. Clin. Invest., 98, 1210-1217.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1210-1217
-
-
O'Dwyer, P.J.1
Szarka, C.E.2
Yao, K.S.3
-
26
-
-
0036846489
-
Protection of retinal pigment epithelial cells from oxidative damage by oltipraz, a cancer chemopreventive agent
-
Nelson,K.C., Armstrong,J.S., Moriarty,S., Cai,J., Wu,M.W., Sternberg,P.,Jr and Jones,D.P. (2002) Protection of retinal pigment epithelial cells from oxidative damage by oltipraz, a cancer chemopreventive agent. Invest. Ophthalmol. Vis. Sci., 43, 3550-3554.
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 3550-3554
-
-
Nelson, K.C.1
Armstrong, J.S.2
Moriarty, S.3
Cai, J.4
Wu, M.W.5
Sternberg Jr., P.6
Jones, D.P.7
-
27
-
-
0038641867
-
A strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites
-
Haggerty,T.J., Zeller,K.I., Osthus,R.C., Wonsey,D.R. and Dang,C.V. (2003) A strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites. Proc. Natl Acad. Sci. USA, 100, 5313-5318.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5313-5318
-
-
Haggerty, T.J.1
Zeller, K.I.2
Osthus, R.C.3
Wonsey, D.R.4
Dang, C.V.5
-
28
-
-
0028978712
-
Involvement of NF-kappa B in the induction of NAD(P)H:Quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C
-
Yao,K.S. and O'Dwyer,P.J. (1995) Involvement of NF-kappa B in the induction of NAD(P)H:quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C. Biochem. Pharmacol., 49, 275-282.
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 275-282
-
-
Yao, K.S.1
O'Dwyer, P.J.2
-
29
-
-
0037245333
-
Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz
-
Kang,K.W., Cho,I.J., Lee,C.H. and Kim,S.G. (2003) Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz. J. Natl Cancer Inst., 95, 53-66.
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 53-66
-
-
Kang, K.W.1
Cho, I.J.2
Lee, C.H.3
Kim, S.G.4
-
30
-
-
0034676269
-
The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells
-
Kim,D.W., Gazourian,L., Quadri,S.A., Romieu-Mourez,R., Sherr,D.H. and Sonenshein,G.E. (2000) The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene, 19, 5498-5506.
-
(2000)
Oncogene
, vol.19
, pp. 5498-5506
-
-
Kim, D.W.1
Gazourian, L.2
Quadri, S.A.3
Romieu-Mourez, R.4
Sherr, D.H.5
Sonenshein, G.E.6
-
31
-
-
0037457572
-
Species, sex and inter-individual differences in DNA repair induced by nine sex steroids in primary cultures of rat and human hepatocytes
-
Martelli,A., Mattioli,F., Angiola,M., Reimann,R. and Brambilla,G. (2003) Species, sex and inter-individual differences in DNA repair induced by nine sex steroids in primary cultures of rat and human hepatocytes. Mutat. Res., 536, 69-78.
-
(2003)
Mutat. Res.
, vol.536
, pp. 69-78
-
-
Martelli, A.1
Mattioli, F.2
Angiola, M.3
Reimann, R.4
Brambilla, G.5
-
32
-
-
0025367754
-
Expression of cytochrome P-450 enzymes in cultured human hepatocytes
-
Morel,F., Beaune,P.H., Ratanasavanh,D., Flinois,J.P., Yang,C.S., Guengerich,F.P. and Guillouzo,A. (1990) Expression of cytochrome P-450 enzymes in cultured human hepatocytes. Eur. J. Biochem., 191, 437-444.
-
(1990)
Eur. J. Biochem.
, vol.191
, pp. 437-444
-
-
Morel, F.1
Beaune, P.H.2
Ratanasavanh, D.3
Flinois, J.P.4
Yang, C.S.5
Guengerich, F.P.6
Guillouzo, A.7
-
33
-
-
0037403686
-
Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products
-
Raucy,J.L. (2003) Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products. Drug Metab. Dispos., 31, 533-539.
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 533-539
-
-
Raucy, J.L.1
-
34
-
-
0026325926
-
Effect of FK 506 on human hepatic cytochromes P-450: Interaction with CyA
-
Pichard,L., Fabre,I., Domergue,J., Joyeux,H. and Maurel,P. (1991) Effect of FK 506 on human hepatic cytochromes P-450: interaction with CyA. Transplant. Proc., 23, 2791-2793.
-
(1991)
Transplant. Proc.
, vol.23
, pp. 2791-2793
-
-
Pichard, L.1
Fabre, I.2
Domergue, J.3
Joyeux, H.4
Maurel, P.5
|