Molecular cytogenetic characterization of rearrangements involving 12p in leukemia

Cancer Genetics and Cytogenetics

Volumn 157, Issue 2, 2005, Pages 134-139

  Vieira, L ^a   Marques, B ^a   Cavaleiro, C ^a   Ambrosio A P ^a   Jorge, M ^b   Neto, A ^c   Costa, J M ^d   Junior E C ^b   Boavida, M G ^a  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b Hospital de Sta Cruz   (Portugal)

^c INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

^d Hospital Distrital de Santarm   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; AGED; ARTICLE; CASE REPORT; CHILD; CHROMOSOME 11P; CHROMOSOME 12; CHROMOSOME 12P; CHROMOSOME 13P; CHROMOSOME 13Q; CHROMOSOME 15; CHROMOSOME 21Q; CHROMOSOME 22Q; CHROMOSOME 5; CHROMOSOME 9; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CHROMOSOME REARRANGEMENT; CHROMOSOME STRUCTURE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; HUMAN; KARYOTYPE; LEUKEMIA; MALE; MIXED MYELODYSPLASTIC MYELOPROLIFERATIVE DISEASE; PRIORITY JOURNAL;

EID: 13844267724     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2004.08.013     Document Type: Article

References (26)

1. Mitelman database of chromosome aberrations in cancer. Available at: http://www.cgap.nci.nih.gov/Chromosomes/Mitelman. Accessed on June 3, 2004.
2. T.R. Golub, G.F. Barker, M. Lovett, and D.G. Gilliland Fusion of PDGF receptor β to a novel ets-like gene, TEL, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation Cell 77 1994 307 316
3. R. Berger, M. Le Coniat, V. Lacronique, M.-T. Daniel, M. Lessard, C. Berthou, P. Marynen, and O. Bernard Chromosome abnormalities of the short arm of chromosome 12 in hematopoietic malignancies: a report including three novel translocations involving the TEL/ETV6 gene Leukemia 11 1997 1400 1403
4. S. Tosi, G. Giudici, G. Mosna, J. Harbott, G. Specchia, G. Grosveld, E. Privitera, L. Kearney, A. Biondi, and G. Cazzaniga Identification of new partner chromosomes involved in fusions with the ETV6 (TEL) gene in hematologic malignancies Genes Chromosomes Cancer 21 1998 223 229
5. Y. Sato, S.K. Bohlander, H. Kobayashi, S. Reshmi, Y. Suto, E.M. Davis, R. Espinosa III, R. Hoopes, K.T. Montgomery, R.S. Kucherlapati, M.M. Le Beau, and J.D. Rowley Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in situ hybridization: TEL (ETV6) is involved in only one half Blood 90 1997 4886 4893
6. I. Wlodarska, R. La Starza, M. Baens, J. Dierlamm, A. Uyttebroeck, D. Selleslag, A. Francine, C. Mecucci, A. Hagemeijer, H. Van den Berghe, and P. Marynen Fluorescence in situ hybridisation characterization of new translocations involving TEL (ETV6) in a wide spectrum of hematologic malignancies Blood 91 1998 1399 1406
7. M.D. Odero, K. Carlson, M.J. Calasanz, I. Lahortiga, V. Chinwalla, and J.D. Rowley Identification of new translocations involving ETV6 in hematologic malignancies by fluorescence in situ hybridization and spectral karyotyping Genes Chromosomes Cancer 31 2001 134 142
8. F. Yagasaki, D. Wakao, Y. Yokoyama, Y. Uchida, I. Murohashi, H. Kayano, M. Taniwaki, A. Matsuda, and M. Bessho Fusion of ETV6 to fibroblast growth factor receptor 3 in peripheral T-cell lymphoma with a t(4;12)(p16;p13) chromosomal translocation Cancer Res 61 2001 8371 8374
9. M.D. Odero, J.L. Vizmanos, J.P. Román, I. Lahortiga, C. Panizo, M.J. Calasanz, N.J. Zeleznik-Le, J.D. Rowley, and F.J. Novo A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome Genes Chromosomes Cancer 35 2002 11 19
10. E.M. Penas, J. Cools, P. Algenstaedt, K. Hinz, D. Seeger, P. Schafhausen, G. Schilling, P. Marynen, D.K. Hossfeld, and J. Dierlamm A novel cryptic translocation t(12;17)(p13;p12∼p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene Genes Chromosomes Cancer 37 2003 79 83
11. Y. Qiao, S. Ogawa, A. Hangaishi, K. Yuji, K. Izutsu, A. Kunisato, Y. Imai, L. Wang, N. Hosoya, Y. Nannya, Y. Sato, K. Maki, K. Mitani, and H. Hirai Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis Leukemia 17 2003 1112 1120
12. T.R. Golub, G.F. Barker, S.K. Bohlander, S.W. Hiebert, D.C. Ward, P. Bray-Ward, E. Morgan, S.C. Raimondi, J.D. Rowley, and D.G. Gilliland Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia Proc Natl Acad Sci USA 92 1995 4917 4921
13. S.P. Romana, M. Mauchauffé, M. Le Coniat, I. Chumakov, D. Le Paslier, R. Berger, and O.A. Bernard The t(12;21) of acute lymphoblastic leukemia results in a TEL-AML1 gene fusion Blood 85 1995 3662 3670
14. I. Wlodarska, P. Marynen, R. La Starza, C. Mecucci, and H. Van den Berghe The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberrations in different hematological malignancies Cytogenet Cell Genet 72 1996 229 235
15. ISCN An international system for human cytogenetic nomenclature F. Mitelman 1995 S. Karger Basel
16. M. Baens, P. Peeters, C. Guo, J. Aerssens, and P. Marynen Genomic organization of TEL: the human ETS-variant gene 6 Genome Res 6 1996 404 413
17. P. Matos, J. Skaug, B. Marques, S. Beck, F. Veríssimo, C. Gespach, M.G. Boavida, S.W. Scherer, and P. Jordan Small GTPase RAC1: structure, localization and expression of the human gene Biochem Biophys Res Commun 277 2000 741 751
18. J.J.M. van Dongen, E.A. Macintyre, J.A. Gabert, E. Delabesse, V. Rossi, G. Saglio, E. Gottardi, A. Rambaldi, G. Dotti, F. Griesinger, A. Parreira, P. Gameiro, M. González Diáz, M. Malec, A.W. Langerak, J.F. San Miguel, and A. Biondi Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease Leukemia 13 1999 1901 1928
19. S. Mathew, S.A. Shurtleff, and S.C. Raimondi Novel cryptic, complex rearrangements involving ETV6-CBFA2 (TEL-AML1) genes identified by fluorescence in situ hybridization in pediatric patients with acute lymphoblastic leukemia Genes Chromosomes Cancer 32 2001 188 193
20. J.L. Wiemels, F.E. Alexander, G. Cazzaniga, A. Biondi, S.P. Mayer, and M. Greaves Microclustering of TEL-AML1 translocation breakpoints in childhood acute lymphoblastic leukemia Genes Chromosomes Cancer 29 2000 219 228
21. G. Cazzaniga, M. Daniotti, S. Tosi, G. Giudici, A. Aloisi, E. Pogliani, L. Kearney, and A. Biondi The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case Cancer Res 61 2001 4666 4670
22. S. Strehl, M. König, M.N. Dworzak, K. Kalwak, and O.A. Haas PAX5/ETV6 fusion defines cytogenetic entity dic(9;12)(p13;p13) Leukemia 17 2003 1121 1123
23. I. Mikkola, B. Heavey, M. Horcher, and M. Busslinger Reversion of B cell commitment upon loss of PAX5 expression Science 297 2002 110 113
24. S.L. Nutt, S. Vambrie, P. Steinlein, Z. Kozmik, A. Rolink, A. Weith, and M. Busslinger Independent regulation of the two PAX5 alleles during B-cell development Nat Genet 21 1999 390 395
25. R. La Starza, M. Stella, N. Testoni, E. Di Bona, S. Ciolli, P. Marynen, M.F. Martelli, F. Mandelli, and C. Mecucci Characterization of 12p molecular events outside ETV6 in complex karyotypes of acute myeloid malignancies Br J Haematol 107 1999 340 346
26. M.D. Odero, K. Carlson, I. Lahortiga, M.J. Calasanz, and J.D. Rowley Molecular cytogenetic characterization of breakpoints in 19 patients with hematologic malignancies and 12p unbalanced translocations Cancer Genet Cytogenet 142 2003 115 119