The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberrations in different hematological malignancies

Cytogenetics and Cell Genetics

Volumn 72, Issue 2-3, 1996, Pages 229-235

  Wlodarska, I ^a   Marynen, P ^a   La Starza, R ^b   Mecucci, C ^b   Van den Berghe, H ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APLASTIC ANEMIA; ARTICLE; CHROMOSOME 12P; CHROMOSOME DELETION; CHROMOSOME REARRANGEMENT; DNA PROBE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOSS; HUMAN; HUMAN CELL; LEUKEMIA; MALE; MYELOMA; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL;

ADULT; AGED; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 12; FEMALE; GENE DELETION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES;

EID: 0029921262     PISSN: 03010171     EISSN: 1424859X     Source Type: Journal    
DOI: 10.1159/000134197     Document Type: Article

References (43)

1. Baens M, Aerssens J, Van Zand K, Cassiman JJ, Van den Berghe H, Marynen P: Isolation and regional assignment of human chromosome 12p cDNAs. Genomics 29:44-52 (1995).
2. Baldini A, Rocchi M, Archidiácono N, Miller OJ, Miller DA: A human alpha satellite DNA subset specific for chromosome 12. Am J hum Genet 46:784-788(1990).
3. Buijs A, Sherr S, van Baal S, van Bezouw S, van der Pias D, van Kessel AG, Riegman P, Deprez RL, Zwarthoff E, Hagemeijer A, Grosveld G: Translocation (12;22)(p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12pl3totheMNl gene on 22ql 1. Oncogene 10: 1511-1519(1995).
4. KipI, to regions involved in human cancer. Cancer Res 55:1199-1205 (1995).
5. Buroker NE, Magenis RE, Weliky K, Bruns G, Litt M: Four restriction fragment length polymorphisms revealed by probes from a single cosmid map to human chromosome 12q. Hum Genet 72:86-94 (1986).
6. Call KM, Glaser T, Ito CY, Buckler AJ, Pelletier J, Haber DA, Rose EA, Krai A, Yeger H, Lewis WH, Jones C, Houseman DE: Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wihns’ tumor locus. Cell 60:509-520(1990).
7. Chafianet M, Baens M, Aerssens J, Schoenmakcrs E, Cassiman JJ, Marynen P: Mapping of an ordered set of 14 cosmids to human chromosome 12p by two color in situ hybridization. Cytogenet Cell Genet 69:27-32 (1995).
8. Chaganti SR, Gaidano G, Louie DC, Dalla Favera R, Chaganti RSK: Diffuse large cell lymphomas exhibit frequent deletions in 9p21 → p22 and 9q31 → q34 regions. Genes Chrom Cancer 12:32-36(1995).
9. Devilder MC, François S, Bosic C, Moreau A, Mellerin MP, Le Paslier D, Bataille R, Moisan JP: Deletion cartography around the D13S25 locus in B cell chronic lymphocytic leukemia and accurate mapping of the involved tumor suppressor gene. Cancer Res 55:1355-1357 (1995).
10. Diaz MO, Rubin CM, Harden A, Ziemin S, Larson RA, Le Beau MM, Rowley JD: Deletions of interferon genes in acute lymphoblastic leukemia. New F.ngl J Med 322:77-82 (1990).
11. Fearon ER and Vogelstein A: A genetic model for colorectal lumorigenesis. Cell 61:759-767 (1990).
12. Gaidano G, Hauptschein RS, Parsa NZ, Offit K, Rao PH, Lenoir G, Knowles DM, Chaganti RSK, Dalla Favera R: Deletions involving two distinct regions of 6q in B cell non Hodgkin-lvmphoma. Blood 80: 1781-1787(1992).
13. Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns GAP: Homozygous deletion in Wilms’ tumours of a zinc finger gene identified by chromosome jumping. Nature 343:774-778 (1990).
14. Golub TR, Barker GF, Lovett M, Gilliland DG: Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 77:307-316 (1994).
15. Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P, Morgan E, Raimondi SC, Rowley JD, Gilliland DG: Fusion of the TEL gene on 12pl 3 to the AMLI geneon21q22 in acute lymphoblastic leukemia. Proc natl Acad Sei. USA 92: 4917-4921 (1995).
16. ISCN: Guideline for Cancer Cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature. Mitelman F (ed) (Karger. Basel 1991).
17. Johansson B, Mertens F, Mitelman F: Cytogenetic deletion maps of hematologic neoplasms: Circumstantial evidence for tumor suppressor loci. Genes Chrom Cancer 8:205-218 (1993).
18. Kobayashi H, Espinosa III R, Femald AA, Begy C, Diaz MO, Le Beau MM, Rowley JD: Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization. Genes Chrom Cancer 8:246-252 (1993).
19. Kobayashi H, Montgomery KT, Bohlander SK, Adra CN, Lim BL, Kucherlapati RS, Donis-Kellcr H, Holt MS, Le Beau MM, Rowley JD: Fluorescence in situ hybridization mapping of translations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases. Blood 10:3473-3482 (1994).
20. Kobayashi H, Rowley JD: Identification of cytogenetically undetected I2pl3 translocations and associated deletions with fluorescence in situ hybridization. Genes Chrom Cancer 12:66-69 (1995).
21. Kucherlapati R, Craig I, Marynen P: Report of the Second International Workshop on Human Chromosome 12 Mapping 1994. Cytogenet Cell Genet 67: 245-276(1994).
22. Le Beau MM, Espinosa R III, Neuman WL, Stock W, Roulston D, Larson RA, Kcinanen M, Westbrook CA: Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. Proc natl Acad Sci. USA 90:5484-5488 (1993).
23. Lee W-H, Bookstein R, Hong F, Young L-J, Shew J-Y, Lee EY-H: Human retinoblastoma susceptibility gene: Cloning, identification, and sequence. Science 235:1394-1399 (1987).
24. Levine AJ: Tumor suppressor genes. BioEssays 12:60-66(1990).
25. Marlton P, Claxton DF, Liu P, Estey EH, Beran M, LeBeau M, Testa JR, Collins FS, Rowley JD, Sicilians MJ: Molecular characterization of 16p deletions associated with inversion 16 defines the eriti-cal fusion for leukemogencsis. Blood 85:772-779 (1995).
26. Mitelman F: Catalog of Chromosome Aberrations in Cancer. 5th ed. Wiley Liss. New York 1994
27. Neuman WL, Rubin CM, Rios RB, Larson RA, Le Beau MM, Rowley JD, Vardiman JW, Schwartz JL, Farber RA: Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders. Blood 79:1501-1510 (1992).
28. Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melte E, Le Beau MM, Diaz MO: Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. Genomics 14:437-443 (1992).
29. Papadopoulos P, Ridge SA, Boucher CA, Stocking C, Wiedemann LM: The novel activation of ABL by fusion to an ets-related gene. TEL I. Cancer Res 55: 34-38(1995).
30. Kip1 gene to 12pl3 and its analysis in leukemias. Cancer Res 55:1206-1210(1995).
31. Kip1. a Cyclin-dependenl kinase inhibitor and a potential mediator of extracellular antintitogenic signals. Cell 78:59-68(1994).
32. Kip1: Chromosomal mapping to 12pl2 →12p13;1 and absence of mutations in human tumors. Cancer Res 55:1211-1214(1995).
33. Quesnel B, Preudhomme C, Philippe N, Vanrumbeke M, Dervite I, Lai JL, Bauters F, Waltel E, Fenaux P: pl6 gene homozygous deletions in acute lymphoblastic leukemia, Blood 85:657-663(1995).
34. Raevmakers P, Van Zand K, Jun L, Cassiman JJ, Van den Berghe H, Marvnen P: A radiation-hybrid map with 60 loci covering the entire short arm of chromosome 12. Genomics 29:170-178 (1995).
35. Raimondi SC, Williams DL, Callihan T, Peiper S, Rivera GK, Murphy SB: Nonrandom involvement of the 12pl2 breakpoint in chromosome abnormalities of childhood acute lymhoblastic leukemia. Blood 68:69-75 (1986).
36. Romana SP, Mauchauffé M, Leconial M, Chumakov I, Le Paslier D, Berger R, Bernard OA: The t(12:21) of acute lymphoblastic leukemia results in a tcl-AML1 gene fusion. Blood 85:3662-3670(1995).
37. Roulston D, Espinosa III R, StolTel M, Bell GI, Le Beau MM: Molecular genetics of myeloid leukemia: Identification of the commonly deleted segment of chromosome 20. Blood 82:3424-3429 (1993).
38. Solomon E, Borrow J, Goddard A: Chromosome aberrations and cancer. Science 254:1153-1160 (1991).
39. Toyoshima H, Hunter T: p27. a novel inhibitor of G Cyclin-CdK protein kinase activity, is related to p21. Cell 78:67-74(1994).
40. Weinberg RA: Tumor suppressor genes. Science 254: 1138-1146(1991).
41. Wlodarska I, Mecucci C, Marynen P, Guo C, Franckx D, La Slarza R, Aventin A, Boslv MF, Martelli JJ, Cassiman JJ, Van den Berghe H: TEL gene is involved in myelodysplastic syndromes with either the typical t(5; 12)(q33;p 13) or its variant t(10; 12)(q24;pl 3). Blood 85:2848-2852(1995).
42. Wlodarska I, Mecucci C, Vandcnbcrghe E, De Wolf-Peeters C, Thomas J, Hilliker C, Schoenmakers E, Stul M, Marynen P, Cassiman JJ, Van den Berghe H: Dup(12)(q 13 → qter) in two t(14:18) negative follicular B-non-Hodgkin's lymphomas. Genes Chrom Cancer 4:302-308 (1992).
43. Zhang J, Baens M, Chaffanet M, Aerssens J, Cassiman J-J, Mary nen P: Isolation and characterization of Notl-end cosmids mapping to human chromosome 12p. in Bullerdiek J (ed): Cytogenetics and Molecular Genetics of Chromosome 12 in Human Solid Tumours (Springer. New York 1994).