메뉴 건너뛰기




Volumn 5, Issue 1, 2005, Pages 101-109

Gene therapy for the prevention of ischemia/reperfusion injury in organ transplantation

Author keywords

Anti apoptotic genes; Cytoprotective genes; Gene therapy; Ischemia reperfusion injury; Transplantation; Viral vectors

Indexed keywords

ADENOVIRUS VECTOR; AMINOTRANSFERASE; BAG 1 PROTEIN; CD4 ANTIGEN; CELL ADHESION MOLECULE; COMPLEMENTARY DNA; COPPER ZINC SUPEROXIDE DISMUTASE; DNA; FERRITIN; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOSOME; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; NITRIC OXIDE REDUCTASE; PLASMID VECTOR; PROTEIN BCL 2; PROTEIN BCL XL; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VIRUS VECTOR;

EID: 13844254508     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/1566523052997451     Document Type: Review
Times cited : (18)

References (71)
  • 1
    • 0038526269 scopus 로고    scopus 로고
    • Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation
    • Abunasra, H.J., Smolenski, R.T., Yap, J., Sheppard, M., O'Brien, T., Yacoub, M.H. (2003) Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation. J Thorac Cardiovasc Surg., 125: 998-1006.
    • (2003) J. Thorac. Cardiovasc. Surg. , vol.125 , pp. 998-1006
    • Abunasra, H.J.1    Smolenski, R.T.2    Yap, J.3    Sheppard, M.4    O'Brien, T.5    Yacoub, M.H.6
  • 2
    • 0036175802 scopus 로고    scopus 로고
    • Gene therapy and solid-organ transplantation
    • Akalin, E., Bromberg, J.S. Gene therapy and solid-organ transplantation. (2002) Kidney Int Suppl., 61 (Suppl 1): 56-60.
    • (2002) Kidney Int. Suppl. , vol.61 , Issue.SUPPL. 1 , pp. 56-60
    • Akalin, E.1    Bromberg, J.S.2
  • 4
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan, N., DiDonato, J.A., Rosette, C., Helmberg, A., Karin, M. (1995) Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science, 270 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 5
    • 0033557372 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-kappaB
    • Badrichani, A.Z., Stroka, D.M., Bilbao, G., Curiel, D.T., Bach, F.H., Ferran, C. (1999) Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-kappaB. J Clin Invest., 103: 543-553.
    • (1999) J. Clin. Invest. , vol.103 , pp. 543-553
    • Badrichani, A.Z.1    Stroka, D.M.2    Bilbao, G.3    Curiel, D.T.4    Bach, F.H.5    Ferran, C.6
  • 10
    • 0027517422 scopus 로고
    • Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide
    • Cassatella, M.A., Meda, L., Bonora, S., Ceska, M., Constantin, G. (1993) Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide. J Exp Med., 178: 2207-2211
    • (1993) J. Exp. Med. , vol.178 , pp. 2207-2211
    • Cassatella, M.A.1    Meda, L.2    Bonora, S.3    Ceska, M.4    Constantin, G.5
  • 13
    • 0037099359 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia/reperfusion injury
    • Coito, A., Buelow, R., Shen, X.D., Amersi, F., Moore, C., Volk, H.D., Busuttil, R.W., Kupiec-Weglinski, J.W: (2002) Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia/reperfusion injury. Transplantation, 74: 96-102.
    • (2002) Transplantation , vol.74 , pp. 96-102
    • Coito, A.1    Buelow, R.2    Shen, X.D.3    Amersi, F.4    Moore, C.5    Volk, H.D.6    Busuttil, R.W.7    Kupiec-Weglinski, J.W.8
  • 17
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C.G., de Vries, J.E. (1991) Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med., 174: 1209-1220.
    • (1991) J. Exp. Med. , vol.174 , pp. 1209-1220
    • de Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 18
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • de Waal Malefyt, R., Haanen, J., Spits, H., Roncarolo, M.G., te Velde, A., Figdor, C., Johnson, K., Kastelein, R., Yssel, H., de Vries, J.E. (1991) Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med., 174: 915-924.
    • (1991) J. Exp. Med. , vol.174 , pp. 915-924
    • de Waal Malefyt, R.1    Haanen, J.2    Spits, H.3    Roncarolo, M.G.4    te Velde, A.5    Figdor, C.6    Johnson, K.7    Kastelein, R.8    Yssel, H.9    de Vries, J.E.10
  • 19
    • 0037096712 scopus 로고    scopus 로고
    • Apoptosis and inflammation in renal reperfusion injury
    • Daemen, M.A., de Vries, B., Buurman, W.A. (2002) Apoptosis and inflammation in renal reperfusion injury. Transplantation, 73: 1693-1700.
    • (2002) Transplantation , vol.73 , pp. 1693-1700
    • Daemen, M.A.1    de Vries, B.2    Buurman, W.A.3
  • 20
    • 0001490181 scopus 로고
    • Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation
    • Drummond, G.S., Kappas, A. (1981) Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proc Natl Acad Sci USA., 78: 6466-6470.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 6466-6470
    • Drummond, G.S.1    Kappas, A.2
  • 22
    • 0034719869 scopus 로고    scopus 로고
    • Optimization of ex vivo pressure mediated delivery of antisense oligodeoxynucleotides to ICAM-1 reduces reperfusion injury in rat cardiac allografts
    • Feeley, B.T., Poston, R.S., Park, A.K., Ennen, M.P., Hoyt, E.G., Vriens, P.W., Robbins, R.C. (2000) Optimization of ex vivo pressure mediated delivery of antisense oligodeoxynucleotides to ICAM-1 reduces reperfusion injury in rat cardiac allografts. Transplantation, 69: 1067-1074.
    • (2000) Transplantation , vol.69 , pp. 1067-1074
    • Feeley, B.T.1    Poston, R.S.2    Park, A.K.3    Ennen, M.P.4    Hoyt, E.G.5    Vriens, P.W.6    Robbins, R.C.7
  • 23
    • 0034670357 scopus 로고    scopus 로고
    • Nuclear factor-kappaB transcription factor decoy treatment inhibits graft coronary artery disease after cardiac transplantation in rodents
    • Feeley, B.T., Miniati, D.N., Park, A.K., Hoyt, E.G., Robbins, R.C. (2000) Nuclear factor-kappaB transcription factor decoy treatment inhibits graft coronary artery disease after cardiac transplantation in rodents. Transplantation, 70: 1560-1568.
    • (2000) Transplantation , vol.70 , pp. 1560-1568
    • Feeley, B.T.1    Miniati, D.N.2    Park, A.K.3    Hoyt, E.G.4    Robbins, R.C.5
  • 24
    • 0035572948 scopus 로고    scopus 로고
    • In vivo transtracheal adenovirus-mediated transfer of human interleukin-10 gene to donor lungs ameliorates ischemia-reperfusion injury and improves early posttransplant graft function in the rat
    • Fischer, S., Liu, M., MacLean, A.A., de Perrot, M., Ho, M., Cardella, J.A., Zhang, X.M., Bai, X.H., Suga, M., Imai, Y., Keshavjee, S. (2001) In vivo transtracheal adenovirus-mediated transfer of human interleukin-10 gene to donor lungs ameliorates ischemia-reperfusion injury and improves early posttransplant graft function in the rat. Hum Gene Ther. 12: 1513-1526.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1513-1526
    • Fischer, S.1    Liu, M.2    MacLean, A.A.3    de Perrot, M.4    Ho, M.5    Cardella, J.A.6    Zhang, X.M.7    Bai, X.H.8    Suga, M.9    Imai, Y.10    Keshavjee, S.11
  • 25
    • 0142244759 scopus 로고    scopus 로고
    • Interleukin 10 gene transfection of donor lungs ameliorates posttransplant cell death by a switch from cellular necrosis to apoptosis
    • Fischer, S., De Perrot, M., Liu, M., MacLean, A.A., Cardella, J.A., Imai, Y., Suga, M., Keshavjee, S. (2003) Interleukin 10 gene transfection of donor lungs ameliorates posttransplant cell death by a switch from cellular necrosis to apoptosis. J Thorac Cardiovasc Surg. 126: 1174-1180.
    • (2003) J. Thorac. Cardiovasc. Surg. , vol.126 , pp. 1174-1180
    • Fischer, S.1    De Perrot, M.2    Liu, M.3    MacLean, A.A.4    Cardella, J.A.5    Imai, Y.6    Suga, M.7    Keshavjee, S.8
  • 27
    • 0032846998 scopus 로고    scopus 로고
    • Gene therapy in transplantation
    • Review
    • Giannoukakis, N., Thomson, A., Robbins, P.. (1999) Gene therapy in transplantation. Gene Ther., 6: 1499-1511. Review.
    • (1999) Gene Ther. , vol.6 , pp. 1499-1511
    • Giannoukakis, N.1    Thomson, A.2    Robbins, P.3
  • 28
    • 0033979275 scopus 로고    scopus 로고
    • Gene therapy in transplantation in the year 2000: Moving towards clinical applications?
    • Review
    • Guillot, C., Le Mauff, B., Cuturi, M.C., Anegon, I. (2000) Gene therapy in transplantation in the year 2000: moving towards clinical applications? Gene Ther., 7: 14-19. Review.
    • (2000) Gene Ther. , vol.7 , pp. 14-19
    • Guillot, C.1    Le Mauff, B.2    Cuturi, M.C.3    Anegon, I.4
  • 34
    • 0037377658 scopus 로고    scopus 로고
    • Preconditioning with tin-protoporphyrin IX attenuates ischemia/reperfusion injury in the rat kidney
    • Kaizu, T., Tamaki, T., Tanaka, M., Uchida, Y., Tsuchihashi, S., Kawamura, A., Kakita, A. (2003) Preconditioning with tin-protoporphyrin IX attenuates ischemia/reperfusion injury in the rat kidney. Kidney Int., 63: 1393-1403.
    • (2003) Kidney Int. , vol.63 , pp. 1393-1403
    • Kaizu, T.1    Tamaki, T.2    Tanaka, M.3    Uchida, Y.4    Tsuchihashi, S.5    Kawamura, A.6    Kakita, A.7
  • 35
    • 0033167922 scopus 로고    scopus 로고
    • Gene therapy using HVJ-liposomes: The best of both worlds?
    • Kaneda, Y., Saeki, Y., Morishita, R. (1999) Gene therapy using HVJ-liposomes: the best of both worlds? Mol Med Today, 5 298-303.
    • (1999) Mol. Med. Today , vol.5 , pp. 298-303
    • Kaneda, Y.1    Saeki, Y.2    Morishita, R.3
  • 37
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • Kay, M.A., Glorioso, J.C., Naldini, L. (2001) Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med, 7: 33-40.
    • (2001) Nat. Med. , vol.7 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 38
    • 0036019201 scopus 로고    scopus 로고
    • Heme Oxygenase 1 Gene Transfer Prevents CD95/Fas Ligand-Mediated Apoptosis and Improves Liver Allograft Survival via Carbon Monoxide Signaling Pathway
    • Ke, B., Buelow, R., Shen, X.D., Melinek, J., Amersi, F., Gao, F., Ritter, T., Volk, H.-D., Busuttil, R.W., Kupiec-Weglinski, J.W. (2002) Heme Oxygenase 1 Gene Transfer Prevents CD95/Fas Ligand-Mediated Apoptosis and Improves Liver Allograft Survival via Carbon Monoxide Signaling Pathway. Hum Gene Ther., 13: 1189-1199.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 1189-1199
    • Ke, B.1    Buelow, R.2    Shen, X.D.3    Melinek, J.4    Amersi, F.5    Gao, F.6    Ritter, T.7    Volk, H.-D.8    Busuttil, R.W.9    Kupiec-Weglinski, J.W.10
  • 39
    • 0037469013 scopus 로고    scopus 로고
    • Kupiec-Weglinski, J.W. (2003a) Interleukin-13 gene transfer protects rat livers from antigen-independent injury induced by ischemia and reperfusion
    • Ke, B., Shen, X.D., Lassman, C.R., Gao, F., Katori, M., Busuttil, R.W., Kupiec-Weglinski, J.W. (2003a) Interleukin-13 gene transfer protects rat livers from antigen-independent injury induced by ischemia and reperfusion. Transplantation, 75: 1118-1123.
    • Transplantation , vol.75 , pp. 1118-1123
    • Ke, B.1    Shen, X.D.2    Lassman, C.R.3    Gao, F.4    Katori, M.5    Busuttil, R.W.6
  • 40
    • 0041861336 scopus 로고    scopus 로고
    • Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/reperfusion injury are heme oxygenase-1 dependent
    • Ke, B., Shen, X.D., Lassman, C.R., Gao, F., Busuttil, R.W., Kupiec-Weglinski, J.W. (2003b) Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/reperfusion injury are heme oxygenase-1 dependent. Am J Transplant., 3: 1076-1082.
    • (2003) Am. J. Transplant. , vol.3 , pp. 1076-1082
    • Ke, B.1    Shen, X.D.2    Lassman, C.R.3    Gao, F.4    Busuttil, R.W.5    Kupiec-Weglinski, J.W.6
  • 41
    • 1142287429 scopus 로고    scopus 로고
    • Gene therapy for liver transplantation using adenoviral vectors: CD40-CD154 blockade by gene transfer of CD40Ig protects rat livers from cold ischemia and reperfusion injury
    • Ke, B., Shen, X.D., Gao, F., Busuttil, R.W., Lowenstein, P., Kupiec-Weglinski, J.W. (2004) Gene therapy for liver transplantation using adenoviral vectors: CD40-CD154 blockade by gene transfer of CD40Ig protects rat livers from cold ischemia and reperfusion injury. Mol. Ther., 9: 38-45.
    • (2004) Mol. Ther. , vol.9 , pp. 38-45
    • Ke, B.1    Shen, X.D.2    Gao, F.3    Busuttil, R.W.4    Lowenstein, P.5    Kupiec-Weglinski, J.W.6
  • 42
    • 3142742209 scopus 로고    scopus 로고
    • Interleukin 13 gene transfer in liver ischemia and reperfusion injury: Role of Stat6 and TLR4 pathways in cytoprotection
    • Ke, B., Shen, X.D., Gao, F., Busuttil, R.W., Kupiec-Weglinski, J.W. (2004) Interleukin 13 gene transfer in liver ischemia and reperfusion injury: Role of Stat6 and TLR4 pathways in cytoprotection. Hum. Gene Ther., 15: 691-698.
    • (2004) Hum. Gene Ther. , vol.15 , pp. 691-698
    • Ke, B.1    Shen, X.D.2    Gao, F.3    Busuttil, R.W.4    Kupiec-Weglinski, J.W.5
  • 43
    • 0028117228 scopus 로고
    • Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer
    • Kolls, J., Peppel, K., Silva, M., Beutler, B. (1994) Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer. Proc Natl Acad Sci U S A. 91: 215-219.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 215-219
    • Kolls, J.1    Peppel, K.2    Silva, M.3    Beutler, B.4
  • 45
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • Lee, T.S., Chau, L.Y. (2002) Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med. 8 240-246
    • (2002) Nat. Med. , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2
  • 46
    • 0034719762 scopus 로고    scopus 로고
    • Delivery of Cu/Zn-superoxide dismutase genes with a viral vector minimizes liver injury and improves survival after liver transplantation in the rat
    • Lehmann, T.G., Wheeler, M.D., Schoonhoven, R., Bunzendahl, H., Samulski, R.J., Thurman, R.G. (2000) Delivery of Cu/Zn-superoxide dismutase genes with a viral vector minimizes liver injury and improves survival after liver transplantation in the rat. Transplantation, 69: 1051-1057
    • (2000) Transplantation , vol.69 , pp. 1051-1057
    • Lehmann, T.G.1    Wheeler, M.D.2    Schoonhoven, R.3    Bunzendahl, H.4    Samulski, R.J.5    Thurman, R.G.6
  • 47
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-beta
    • Letterio, J.J., Roberts, A.B. (1998) Regulation of immune responses by TGF-beta. Annu Rev Immunol., 16: 137-161.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 48
    • 0033767577 scopus 로고    scopus 로고
    • Therapeutic applications of transcription factor decoy oligonucleotides
    • Mann, M.J., Dzau, V.J. (2000) Therapeutic applications of transcription factor decoy oligonucleotides. J Clin Invest, 106 1071-1075.
    • (2000) J. Clin. Invest. , vol.106 , pp. 1071-1075
    • Mann, M.J.1    Dzau, V.J.2
  • 49
    • 0034913116 scopus 로고    scopus 로고
    • Nonviral vectors in the new millennium: Delivery barriers in gene transfer
    • Nishikawa, M., Huang, L. (2001) Nonviral vectors in the new millennium: delivery barriers in gene transfer. Hum Gene Ther., 12: 861-870.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 861-870
    • Nishikawa, M.1    Huang, L.2
  • 50
    • 0030764114 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of viral interleukin-10 inhibits the immune response to both alloantigen and adenoviral antigen
    • Qin, L., Ding, Y., Pahud, D.R., Robson, N.D., Shaked, A., Bromberg, J.S. (1997) Adenovirus-mediated gene transfer of viral interleukin-10 inhibits the immune response to both alloantigen and adenoviral antigen. Hum Gene Ther., 8: 1365-1374.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 1365-1374
    • Qin, L.1    Ding, Y.2    Pahud, D.R.3    Robson, N.D.4    Shaked, A.5    Bromberg, J.S.6
  • 51
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J.C. (1994) Bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124: 1-6
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 52
    • 4344584558 scopus 로고    scopus 로고
    • Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
    • Ricchetti, G.A., Williams, L.M., Foxwell, B.M. (2004) Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide. J Leukoc Biol., 76: 719-726.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 719-726
    • Ricchetti, G.A.1    Williams, L.M.2    Foxwell, B.M.3
  • 53
    • 0033914386 scopus 로고    scopus 로고
    • Ischemia/reperfusion injury-mediated down-regulation of adenovirus-mediated gene expression in a rat heart transplantation model is inhibited by co-application of a TNFRp55-Ig chimeric construct
    • Ritter, T., Schroder, G., Risch, K., Vergopoulos, A., Shean, M.K., Kolls, J., Brock, J., Lehmann, M., Volk, H.D. (2000) Ischemia/ reperfusion injury-mediated down-regulation of adenovirus-mediated gene expression in a rat heart transplantation model is inhibited by co-application of a TNFRp55-Ig chimeric construct. Gene Ther., 7 1238-1243.
    • (2000) Gene Ther. , vol.7 , pp. 1238-1243
    • Ritter, T.1    Schroder, G.2    Risch, K.3    Vergopoulos, A.4    Shean, M.K.5    Kolls, J.6    Brock, J.7    Lehmann, M.8    Volk, H.D.9
  • 55
    • 0037308148 scopus 로고    scopus 로고
    • Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection
    • Shen. X.D., Ke, B., Zhai, Y., Gao, F., Anselmo, D,, Lassman, C.R., Busuttil, R.W., Kupiec-Weglinski, J.W. (2003) Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection. Hepatology. 37: 296-303.
    • (2003) Hepatology , vol.37 , pp. 296-303
    • Shen, X.D.1    Ke, B.2    Zhai, Y.3    Gao, F.4    Anselmo, D.5    Lassman, C.R.6    Busuttil, R.W.7    Kupiec-Weglinski, J.W.8
  • 57
    • 0035707492 scopus 로고    scopus 로고
    • Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs
    • Soares, M.P., Brouard, S., Smith, R.N., Bach, F.H. (2001) Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs. Immunol Rev., 184: 275-285.
    • (2001) Immunol. Rev. , vol.184 , pp. 275-285
    • Soares, M.P.1    Brouard, S.2    Smith, R.N.3    Bach, F.H.4
  • 58
    • 0035669174 scopus 로고    scopus 로고
    • Phosphorothioate/methoxyethyl-modified ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury
    • Stepkowski, S.M., Chen, W., Bennett, C.F., Condon, T.P., Stecker, K., Tian, L., Kahan, B.D. Phosphorothioate/methoxyethyl-modified (2001) ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury. Transplant Proc, 33: 3705-3706.
    • (2001) Transplant. Proc. , vol.33 , pp. 3705-3706
    • Stepkowski, S.M.1    Chen, W.2    Bennett, C.F.3    Condon, T.P.4    Stecker, K.5    Tian, L.6    Kahan, B.D.7
  • 61
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama, S., Sato, T., Krajewski, S., Kochel, K., Irie, S., Millan, J.A., Reed, J.C. (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell, 80: 279-284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 62
    • 0033534588 scopus 로고    scopus 로고
    • An evolutionarily conserved family of Hsp70/Hsc7O molecular chaperone regulators
    • Takayama, S., Xie, Z., Reed, J.C. (1999) An evolutionarily conserved family of Hsp70/Hsc7O molecular chaperone regulators. J Biol Chem., 279: 781-786.
    • (1999) J. Biol. Chem. , vol.279 , pp. 781-786
    • Takayama, S.1    Xie, Z.2    Reed, J.C.3
  • 63
    • 0029114163 scopus 로고
    • High survival rates of kidney transplants from spousal and living unrelated donors
    • Terasaki, P.I., Cecka, J.M., Gjertson, D.W., Takemoto, S. (1995) High survival rates of kidney transplants from spousal and living unrelated donors. N Engl J Med., 333: 333-336
    • (1995) N. Engl. J. Med. , vol.333 , pp. 333-336
    • Terasaki, P.I.1    Cecka, J.M.2    Gjertson, D.W.3    Takemoto, S.4
  • 64
    • 0035960264 scopus 로고    scopus 로고
    • Transplantation of organs from marginal donors
    • Tullius, S.G., Volk, H.D., Neuhaus, P. (2001) Transplantation of organs from marginal donors. Transplantation, 72: 1341-1349.
    • (2001) Transplantation , vol.72 , pp. 1341-1349
    • Tullius, S.G.1    Volk, H.D.2    Neuhaus, P.3
  • 66
    • 0037377634 scopus 로고    scopus 로고
    • Heme oxygenase-1 attenuates ischemia/ reperfusion-induced apoptosis and improves survival in rat renal allografts
    • Wagner, M., Cadetg, P., Ruf, R., Mazzucchelli, L., Ferrari, P., Redaelli, C.A. (2003) Heme oxygenase-1 attenuates ischemia/ reperfusion-induced apoptosis and improves survival in rat renal allografts. Kidney Int, 63: 1564-1573.
    • (2003) Kidney Int. , vol.63 , pp. 1564-1573
    • Wagner, M.1    Cadetg, P.2    Ruf, R.3    Mazzucchelli, L.4    Ferrari, P.5    Redaelli, C.A.6
  • 67
    • 0033856775 scopus 로고    scopus 로고
    • Viral vectors for gene transfer: A review of their use in the treatment of human diseases
    • Walther, W., Stein, U. (2000) Viral vectors for gene transfer: a review of their use in the treatment of human diseases. Drugs. 60: 249-271.
    • (2000) Drugs , vol.60 , pp. 249-271
    • Walther, W.1    Stein, U.2
  • 68
    • 0035685562 scopus 로고    scopus 로고
    • Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury
    • Wheeler, M.D., Katuna, M., Smutney, O.M., Froh, M., Dikalova, A., Mason, R.P., Samulski, R.J., Thurman, R.G. (2001) Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury. Hum Gene Ther, 12: 2167-2177.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 2167-2177
    • Wheeler, M.D.1    Katuna, M.2    Smutney, O.M.3    Froh, M.4    Dikalova, A.5    Mason, R.P.6    Samulski, R.J.7    Thurman, R.G.8
  • 69
    • 0030690558 scopus 로고    scopus 로고
    • Gene therapy and allotransplantation
    • Wood, K.J. (1997) Gene therapy and allotransplantation. Curr. Opin. Immunol, 9: 662-668.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 662-668
    • Wood, K.J.1
  • 71
    • 0035082637 scopus 로고    scopus 로고
    • Subcellular site of superoxide dismutase expression differentially controls AP-1 activity and injury in mouse liver following ischemia/reperfusion
    • Zhou, W., Zhang, Y., Hosch, M.S., Lang, A., Zwacka, R.M., Engelhardt, J.F. (2001) Subcellular site of superoxide dismutase expression differentially controls AP-1 activity and injury in mouse liver following ischemia/reperfusion. Hepatology, 33: 902-914.
    • (2001) Hepatology , vol.33 , pp. 902-914
    • Zhou, W.1    Zhang, Y.2    Hosch, M.S.3    Lang, A.4    Zwacka, R.M.5    Engelhardt, J.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.