Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity

Genes and Development

Volumn 19, Issue 4, 2005, Pages 502-513

  Schmidt, Andreas ^a   Duncan, Peter I ^a,c   Rauh, Nadine R ^a   Sauer, Guido ^a   Fry, Andrew M ^b   Nigg, Erich A ^a   Mayer, Thomas U ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Anaphase promoting complex cyclosome; Cell cycle; Cytostatic factor; Mitotic exit; Polo like kinase; Xenopus

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CYCLINE; F BOX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; POLO LIKE KINASE; PROTEIN PLX1; PROTEIN XERP1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; UO 126;

ANAPHASE; ARTICLE; CELL CYCLE; GENETIC CONSERVATION; IMMUNOBLOTTING; MASS SPECTROMETRY; METAPHASE; NONHUMAN; OOCYTE MATURATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SISTER CHROMATID; UBIQUITINATION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; DNA PRIMERS; F-BOX PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-MOS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-PROTEIN LIGASE COMPLEXES; XENOPUS; XENOPUS PROTEINS;

EID: 13844253522     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.320705     Document Type: Article

References (38)

1. Barr, F.A., Sillje, H.H., and Nigg, E.A. 2004. Polo-like kinases and the orchestration of cell division. Nat. Rev. Mol. Cell Biol 5: 429-440.
2. Brassac, T., Castro, A., Lorca, T., Le Peuch, C., Doree, M., Labbe, J.C., and Galas, S. 2000. The polo-like kinase Plx1 prevents premature inactivation of the APC(Fizzy)-dependent pathway in the early Xenopus cell cycle. Oncogene 19: 3782-3790.
3. Desai, A., Murray, A., Mitchison, T.J., and Walczak, C.E. 1999. The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol. 61: 385-412.
4. Descombes, P. and Nigg, E.A. 1998. The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J. 17: 1328-1335.
5. Donaldson, M.M., Tavares, A.A., Ohkura, H., Deak, P., and Glover, D.M. 2001. Metaphase arrest with centromere separation in polo mutants of Drosophila. J. Cell Biol. 153: 663-676.
6. Dong, X., Zavitz, K.H., Thomas, B.J., Lin, M., Campbell, S., and Zipursky, S.L. 1997. Control of G1 in the developing Drosophila eye: real regulates Cyclin A. Genes & Dev. 11: 94-105.
7. Elia, A.E., Rellos, P., Haire, L.F., Chao, J.W., Ivins, F.J., Hoepker, K., Mohammad, D., Cantley, L.C., Smerdon, S.J., and Yaffe, M.B. 2003. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell 115: 83-95.
8. Fuchs, S.Y., Spiegelman, V.S., and Kumar, K.G. 2004. The many faces of β-TrCP E3 ubiquitin ligases: Reflections in the magic mirror of cancer. Oncogene 23: 2028-2036.
9. Funabiki, H. and Murray, A.W. 2000. The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement. Cell 102: 411-424.
10. Gabrielli, B.G., Roy, L.M., and Maller, J.L. 1993. Requirement for Cdk2 in cytostatic factor-mediated metaphase II arrest. Science 259: 1766-1769.
11. Gietz, R.D. and Woods, R.A. 2002. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol. 350: 87-96.
12. Golan, A., Yudkovsky, Y., and Hershko, A. 2002. The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk. J. Biol. Chem. 277: 15552-15557.
13. Hansen, D.V., Loktev, A.V., Ban, K.H., and Jackson, P.K. 2004. Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFβTrCP-dependent destruction of the APC inhibitor Emil. Mol. Biol. Cell 15: 5623-5634.
14. Kosako, H., Gotoh, Y., and Nishida, E. 1994. Mitogen-activated protein kinase kinase is required for the mos-induced metaphase arrest. J. Biol. Chem. 269: 28354-28358.
15. Kotani, S., Tugendreich, S., Fujii, M., Jorgensen, P.M., Watanabe, N., Hoog, C., Hieter, P., and Todokoro, K. 1998. PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression. Mol. Cell 1: 371-380.
16. Kraft, C., Herzog, F., Gieffers, C., Mechtler, K., Hagting, A., Pines, J., and Peters, J.M. 2003. Mitotic regulation of the human anaphase-promoting complex by phosphorylation. EMBO J. 22: 6598-6609.
17. Kramer, E.R., Gieffers, C., Holzl, G., Hengstschlager, M., and Peters, J.M. 1998. Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family. Curr. Biol. 8: 1207-1210.
18. Liu, J., Lewellyn, A.L., Chen, L.G., and Maller, J.L. 2004. The polo box is required for multiple functions of plx1 in mitosis. J. Biol. Chem. 279: 21367-21373.
19. Lorca, T., Cruzalegui, F.H., Fesquet, D., Cavadore, J.C., Mery, J., Means, A., and Doree, M. 1993. Calmodulin-dependent protein kinase II mediates inactivation of MPF and CSF upon fertilization of Xenopus eggs. Nature 366: 270-273.
20. Masui, Y. and Markert, C.L. 1971. Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes. J. Exp. Zool. 177: 129-145.
21. Moshe, Y., Boulaire, J., Pagano, M., and Hershko, A. 2004. Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome. Proc. Natl. Acad. Sci. 101: 7937-7942.
22. Murray, A.W. 1991. Cell cycle extracts. Methods Cell Biol. 36.
23. -. 2004. Recycling the cell cycle: Cyclins revisited. Cell 116: 221-234.
24. Ohsumi, K., Koyanagi, A., Yamamoto, T.M., Gotoh, T., and Kishimoto, T. 2004. Emil-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest. Proc. Natl. Acad. Sci. 101: 12531-12536.
25. Rappsilber, J., Ishihama, Y., and Mann, M. 2003. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 75: 663-670.
26. Regan-Reimann, J.D., Duong, Q.V., and Jackson, P.K. 1999. Identification of novel F-box proteins in Xenopus laevis. Curr. Biol. 9: R762-R763.
27. Reimann, J.D. and Jackson, P.K. 2002. Emil is required for cytostatic factor arrest in vertebrate eggs. Nature 416: 850-854.
28. Reimann, J.D., Freed, E., Hsu, J.Y., Kramer, E.R., Peters, J.M., and Jackson, P.K. 2001a. Emil is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell 105: 645-655.
29. Reimann, J.D., Gardner, B.E., Margottin-Goguet, F., and Jackson, P.K. 2001b. Emil regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. Genes & Dev. 15: 3278-3285.
30. Sagata, N., Watanabe, N., Vande Woude, G.F., and Ikawa, Y. 1989. The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs. Nature 342: 512-518.
31. Schwab, M.S., Roberts, B.T., Gross, S.D., Tunquist, B.J., Taieb, F.E., Lewellyn, A.L., and Maller, J.L. 2001. Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation. Curr. Biol. 11: 141-150.
32. Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68: 850-858.
33. Shirayama, M., Zachariae, W., Ciosk, R., and Nasmyth, K. 1998. The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J. 17: 1336-1349.
34. Stemmann, O., Zou, H., Gerber, S.A., Gygi, S.P., and Kirschner, M.W. 2001. Dual inhibition of sister chromatid separation at metaphase. Cell 107: 715-726.
35. Sturgill, T.W., Ray, L.B., Erikson, E., and Mailer, J.L. 1988. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334: 715-718.
36. Tunquist, B.J. and Maller, J.L. 2003. Under arrest: Cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs. Genes & Dev. 17: 683-710.
37. Tunquist, B.J., Schwab, M.S., Chen, L.G., and Maller, J.L. 2002. The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor. Curr. Biol. 12: 1027-1033.
38. Tunquist, B.J., Eyers, P.A., Chen, L.G., Lewellyn, A.L., and Maller, J.L. 2003. Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest. J. Cell Biol. 163: 1231-1242.