메뉴 건너뛰기




Volumn 54, Issue 3, 2005, Pages 391-396

Changes in blood pressure and plasma catecholamine levels during prolonged hyperinsulinemia

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSUMAN RAPID;

EID: 13844252099     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2004.10.005     Document Type: Article
Times cited : (47)

References (52)
  • 1
    • 0024160877 scopus 로고
    • Banting Lecture 1988: Role of insulin resistance in human disease
    • G.M. Reaven Banting Lecture 1988: role of insulin resistance in human disease Diabetes 37 1988 1595 1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 0026021161 scopus 로고
    • Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease
    • R.A. DeFronzo, and E. Ferrannini Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease Diabetes Care 14 1991 173 194
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • Defronzo, R.A.1    Ferrannini, E.2
  • 4
    • 0021928204 scopus 로고
    • Hyperinsulinaemia: A link between hypertension, obesity and glucose intolerance
    • M. Modan, H. Halkin, and S. Almog Hyperinsulinaemia: a link between hypertension, obesity and glucose intolerance J. Clin. Invest. 75 1985 809 817
    • (1985) J. Clin. Invest. , vol.75 , pp. 809-817
    • Modan, M.1    Halkin, H.2    Almog, S.3
  • 5
    • 0021884286 scopus 로고
    • The cardiovascular risk profile of adolescents with insulin-dependent diabetes mellitus
    • K.J. Cruickshanks, T.J. Orchard, and D.J. Becker The cardiovascular risk profile of adolescents with insulin-dependent diabetes mellitus Diabetes Care 8 1985 118 124
    • (1985) Diabetes Care , vol.8 , pp. 118-124
    • Cruickshanks, K.J.1    Orchard, T.J.2    Becker, D.J.3
  • 6
    • 0023127245 scopus 로고
    • Sex differences in the coronary heart disease risk profile: A possible role for insulin
    • R.P. Donahue, T.J. Orchard, and D.J. Becker Sex differences in the coronary heart disease risk profile: a possible role for insulin Am. J. Epidemiol. 125 1987 650 657
    • (1987) Am. J. Epidemiol. , vol.125 , pp. 650-657
    • Donahue, R.P.1    Orchard, T.J.2    Becker, D.J.3
  • 7
    • 0023214682 scopus 로고
    • A role for insulin in the aetiology and course of hypertension?
    • G.M. Reaven, and B.B. Hoffman A role for insulin in the aetiology and course of hypertension? Lancet 2 1987 435 437
    • (1987) Lancet , vol.2 , pp. 435-437
    • Reaven, G.M.1    Hoffman, B.B.2
  • 8
    • 0023832784 scopus 로고
    • Hypertension and hyperinsulinaemia: A relation in diabetes but not essential hypertension
    • J.N. Mbanya, T.H. Thomas, and R. Wilkinson Hypertension and hyperinsulinaemia: a relation in diabetes but not essential hypertension Lancet 1 1988 733 734
    • (1988) Lancet , vol.1 , pp. 733-734
    • Mbanya, J.N.1    Thomas, T.H.2    Wilkinson, R.3
  • 9
    • 0035118204 scopus 로고    scopus 로고
    • Urinary epinephrine and norepinephrine interrelations with obesity, insulin, and the metabolic syndrome in Hong Kong Chinese
    • Z.S. Lee, J.A. Critchley, and B. Tomlinson Urinary epinephrine and norepinephrine interrelations with obesity, insulin, and the metabolic syndrome in Hong Kong Chinese Metabolism 50 2001 135 143
    • (2001) Metabolism , vol.50 , pp. 135-143
    • Lee, Z.S.1    Critchley, J.A.2    Tomlinson, B.3
  • 10
    • 0027409551 scopus 로고
    • An epidemiological test of the hyperinsulinemia-hypertension hypothesis
    • D.C. Muller, D. Elahi, and R.E. Pratley An epidemiological test of the hyperinsulinemia-hypertension hypothesis J. Clin. Endocrinol. Metab. 76 1993 544 548
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , pp. 544-548
    • Muller, D.C.1    Elahi, D.2    Pratley, R.E.3
  • 11
    • 0025649883 scopus 로고
    • An inconsistent relationship between insulin and blood pressure in three Pacific island populations
    • V.R. Collins, G.K. Dowse, and C.F. Finch An inconsistent relationship between insulin and blood pressure in three Pacific island populations J. Clin. Epidemiol. 43 1990 1369 1378
    • (1990) J. Clin. Epidemiol. , vol.43 , pp. 1369-1378
    • Collins, V.R.1    Dowse, G.K.2    Finch, C.F.3
  • 12
    • 0030020797 scopus 로고    scopus 로고
    • Nocturnal blood pressure elevation is related to adrenomedullary hyperactivity, but not to hyperinsulinemia, in nonobese normoalbuminuric type 1 diabetes
    • A. Peters, S. Gromeier, and T. Kohlmann Nocturnal blood pressure elevation is related to adrenomedullary hyperactivity, but not to hyperinsulinemia, in nonobese normoalbuminuric type 1 diabetes J. Clin. Endocrinol. Metab. 81 1996 507 512
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 507-512
    • Peters, A.1    Gromeier, S.2    Kohlmann, T.3
  • 13
    • 0014220939 scopus 로고
    • Asymptomatic diabetes mellitus in normal weight subjects with hypertension. Studies on glucose tolerance, serum insulin and nonesterified fatty acids in essential hypertension
    • P. Dieterle, H. Fehm, and W. Ströder Asymptomatic diabetes mellitus in normal weight subjects with hypertension. Studies on glucose tolerance, serum insulin and nonesterified fatty acids in essential hypertension Dtsch. Med. Wochenschr. 52 1967 2376 2381
    • (1967) Dtsch. Med. Wochenschr. , vol.52 , pp. 2376-2381
    • Dieterle, P.1    Fehm, H.2    Ströder, W.3
  • 14
    • 0030025673 scopus 로고    scopus 로고
    • Hypertension and associated metabolic abnormalities-the role of insulin resistance and the sympathoadrenal system
    • G.M. Reaven, H. Lithell, and L. Landsberg Hypertension and associated metabolic abnormalities-the role of insulin resistance and the sympathoadrenal system N. Engl. J. Med. 334 1996 374 381
    • (1996) N. Engl. J. Med. , vol.334 , pp. 374-381
    • Reaven, G.M.1    Lithell, H.2    Landsberg, L.3
  • 15
    • 0025015629 scopus 로고
    • Hyperinsulinemia and elevated blood pressure: Cause, confounder, or coincidence
    • R.P. Donahue, J.S. Skyler, and N. Schneiderman Hyperinsulinemia and elevated blood pressure: cause, confounder, or coincidence Am. J. Epidemiol. 132 1990 827 836
    • (1990) Am. J. Epidemiol. , vol.132 , pp. 827-836
    • Donahue, R.P.1    Skyler, J.S.2    Schneiderman, N.3
  • 16
    • 0026075182 scopus 로고
    • Re: Hyperinsulinemia and elevated blood pressure: Cause, confounder, or coincidence
    • R.J. Jarret Re: Hyperinsulinemia and elevated blood pressure: cause, confounder, or coincidence Am. J. Epidemiol. 134 1991 327 328
    • (1991) Am. J. Epidemiol. , vol.134 , pp. 327-328
    • Jarret, R.J.1
  • 17
    • 0026722182 scopus 로고
    • The sympathetic response to euglycemic hyperinsulinaemia: Evidence from microelectrode nerve recordings in healthy subjects
    • C. Berne, J. Fagius, and T. Pollare The sympathetic response to euglycemic hyperinsulinaemia: evidence from microelectrode nerve recordings in healthy subjects Diabetologia 35 1992 873 879
    • (1992) Diabetologia , vol.35 , pp. 873-879
    • Berne, C.1    Fagius, J.2    Pollare, T.3
  • 18
    • 0019483909 scopus 로고
    • Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man
    • J.W. Rowe, J.B. Young, and K.L. Minaker Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man Diabetes 30 1981 219 225
    • (1981) Diabetes , vol.30 , pp. 219-225
    • Rowe, J.W.1    Young, J.B.2    Minaker, K.L.3
  • 19
    • 13344249788 scopus 로고    scopus 로고
    • Effects of insulin on vascular tone and sympathetic nervous system in NIDDM
    • C.J.J. Tack, P. Smits, and J.J. Willemsen Effects of insulin on vascular tone and sympathetic nervous system in NIDDM Diabetes 45 1996 15 22
    • (1996) Diabetes , vol.45 , pp. 15-22
    • Tack, C.J.J.1    Smits, P.2    Willemsen, J.J.3
  • 20
    • 0017393657 scopus 로고
    • Intravenous insulin causing loss of intravascular water and albumin and increased adrenergic nervous activity in diabetics
    • H.J.G. Gundersen, and N.J. Christensen Intravenous insulin causing loss of intravascular water and albumin and increased adrenergic nervous activity in diabetics Diabetes 26 1977 551 557
    • (1977) Diabetes , vol.26 , pp. 551-557
    • Gundersen, H.J.G.1    Christensen, N.J.2
  • 21
    • 0028840916 scopus 로고
    • The glucose clamp procedure activates the sympathetic nervous system even in the absence of hyperinsulinemia
    • A. Moan, A. Hoieggen, and G. Nordby The glucose clamp procedure activates the sympathetic nervous system even in the absence of hyperinsulinemia J. Clin. Endocrinol. Metab. 80 1995 3151 3154
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3151-3154
    • Moan, A.1    Hoieggen, A.2    Nordby, G.3
  • 22
    • 0026515392 scopus 로고
    • Evidence against the hypothesis that hyperinsulinemia increases sympathetic nervous system activity in man
    • A. Mitrakou, M. Mokan, and G. Bolli Evidence against the hypothesis that hyperinsulinemia increases sympathetic nervous system activity in man Metabolism 41 1992 198 200
    • (1992) Metabolism , vol.41 , pp. 198-200
    • Mitrakou, A.1    Mokan, M.2    Bolli, G.3
  • 23
    • 0025763533 scopus 로고
    • Renal and cardiovascular effects of exogenous insulin in healthy volunteers
    • R.O. Gans, T.L. vd, and H.J. Bilo Renal and cardiovascular effects of exogenous insulin in healthy volunteers Clin. Sci. (Lond.) 80 1991 219 225
    • (1991) Clin. Sci. (Lond.) , vol.80 , pp. 219-225
    • Gans, R.O.1    Vd, T.L.2    Bilo, H.J.3
  • 24
    • 0030666657 scopus 로고    scopus 로고
    • 'Physiological' hyperinsulinaemia increases distal artery systolic blood pressure without changing proximal blood pressure
    • C.J. O'Callaghan, K. Komersova, and H. Krum 'Physiological' hyperinsulinaemia increases distal artery systolic blood pressure without changing proximal blood pressure Clin. Sci. (Lond.) 93 1997 535 540
    • (1997) Clin. Sci. (Lond.) , vol.93 , pp. 535-540
    • O'Callaghan, C.J.1    Komersova, K.2    Krum, H.3
  • 25
    • 0025995364 scopus 로고
    • Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
    • E.A. Anderson, R.P. Hoffmann, and T.W. Balon Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans J. Clin. Invest. 87 1991 2246 2252
    • (1991) J. Clin. Invest. , vol.87 , pp. 2246-2252
    • Anderson, E.A.1    Hoffmann, R.P.2    Balon, T.W.3
  • 26
    • 0023748234 scopus 로고
    • Effect of starvation and food intake on sympathetic activity
    • T. Sakaguchi, K. Arase, and J.S. Fisler Effect of starvation and food intake on sympathetic activity Am. J. Physiol. 255 1988 R284 R288
    • (1988) Am. J. Physiol. , vol.255
    • Sakaguchi, T.1    Arase, K.2    Fisler, J.S.3
  • 27
    • 0030063781 scopus 로고    scopus 로고
    • Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men
    • M. Bergendahl, M.L. Vance, and A. Iranmanesh Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men J. Clin. Endocrinol. Metab. 81 1996 692 699
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 692-699
    • Bergendahl, M.1    Vance, M.L.2    Iranmanesh, A.3
  • 29
    • 0019415752 scopus 로고
    • Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus
    • O.G. Kolterman, R.S. Gray, P. Burtstein, J. Insel, J.A. Scarlett, and J.M. Olefsky Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus J. Clin. Invest. 68 1981 957 969
    • (1981) J. Clin. Invest. , vol.68 , pp. 957-969
    • Kolterman, O.G.1    Gray, R.S.2    Burtstein, P.3    Insel, J.4    Scarlett, J.A.5    Olefsky, J.M.6
  • 30
    • 0028085621 scopus 로고
    • Hemodynamic actions of insulin
    • A.D. Baron Hemodynamic actions of insulin Am. J. Physiol. 267 1994 E187 E202
    • (1994) Am. J. Physiol. , vol.267
    • Baron, A.D.1
  • 31
    • 0028216451 scopus 로고
    • Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin
    • M. Muntzel, T. Beltz, and A.L. Mark Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin Hypertension 23 1994 1059 1062
    • (1994) Hypertension , vol.23 , pp. 1059-1062
    • Muntzel, M.1    Beltz, T.2    Mark, A.L.3
  • 32
    • 0022359768 scopus 로고
    • Insulin-mediated glucose metabolism in the relationship between dietary intake and sympathetic nervous system activity
    • L. Landsberg, and J.B. Young Insulin-mediated glucose metabolism in the relationship between dietary intake and sympathetic nervous system activity Int. J. Obes. 9 Suppl. 2 1985 63 68
    • (1985) Int. J. Obes. , vol.9 , Issue.2 SUPPL. , pp. 63-68
    • Landsberg, L.1    Young, J.B.2
  • 33
    • 0020998384 scopus 로고
    • Circumventricular organs: Receptors and mediators of direct peptide hormone action on brain
    • M. Van Houten, and B.I. Posner Circumventricular organs: receptors and mediators of direct peptide hormone action on brain Adv. Metab. Disord. 10 1983 269 289
    • (1983) Adv. Metab. Disord. , vol.10 , pp. 269-289
    • Van Houten, M.1    Posner, B.I.2
  • 34
    • 0020661448 scopus 로고
    • Effect of insulin on central catecholamines
    • A. Sauter, M. Goldstein, and J. Engel Effect of insulin on central catecholamines Brain Res. 260 1983 330 333
    • (1983) Brain Res. , vol.260 , pp. 330-333
    • Sauter, A.1    Goldstein, M.2    Engel, J.3
  • 35
    • 0019387836 scopus 로고
    • Insulin-induced enhancement of uptake of noradrenaline in atrial strips
    • B. Bhagat, W.J. Burke, and N.S. Dhalla Insulin-induced enhancement of uptake of noradrenaline in atrial strips Br. J. Pharmacol. 74 1981 325 332
    • (1981) Br. J. Pharmacol. , vol.74 , pp. 325-332
    • Bhagat, B.1    Burke, W.J.2    Dhalla, N.S.3
  • 36
    • 0026637065 scopus 로고
    • Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension
    • G. Lembo, R. Napoli, and B. Capaldo Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension J. Clin. Invest. 90 1992 24 29
    • (1992) J. Clin. Invest. , vol.90 , pp. 24-29
    • Lembo, G.1    Napoli, R.2    Capaldo, B.3
  • 37
    • 0033635326 scopus 로고    scopus 로고
    • Increase in systolic blood pressure and catecholamine level during hyperinsulinemia in a placebo-controlled euglycemic clamp in healthy subjects
    • W. Kern, A. Fittje, and W. Fohr Increase in systolic blood pressure and catecholamine level during hyperinsulinemia in a placebo-controlled euglycemic clamp in healthy subjects Exp. Clin. Endocrinol. Diabetes 108 2000 498 505
    • (2000) Exp. Clin. Endocrinol. Diabetes , vol.108 , pp. 498-505
    • Kern, W.1    Fittje, A.2    Fohr, W.3
  • 38
    • 0028136625 scopus 로고
    • Relative roles of insulin and hypoglycaemia on induction of neuroendocrine responses to, symptoms of, and deterioration of cognitive function in hypoglycaemia in male and female humans
    • C. Fanelli, S. Pampanelli, and L. Epifano Relative roles of insulin and hypoglycaemia on induction of neuroendocrine responses to, symptoms of, and deterioration of cognitive function in hypoglycaemia in male and female humans Diabetologia 37 1994 797 807
    • (1994) Diabetologia , vol.37 , pp. 797-807
    • Fanelli, C.1    Pampanelli, S.2    Epifano, L.3
  • 39
    • 0024519447 scopus 로고
    • Adrenomedullary hyperactivity in type I diabetic patients before and during continuous subcutaneous insulin treatment
    • G. Del Rio, A. Baldini, and C. Carani Adrenomedullary hyperactivity in type I diabetic patients before and during continuous subcutaneous insulin treatment J. Clin. Endocrinol. Metab. 68 1989 555 559
    • (1989) J. Clin. Endocrinol. Metab. , vol.68 , pp. 555-559
    • Del Rio, G.1    Baldini, A.2    Carani, C.3
  • 40
    • 0027008266 scopus 로고
    • High urinary excretion of adrenaline in insulin dependent diabetic subjects
    • G. Del Rio, P. Marrama, and L. Della Casa High urinary excretion of adrenaline in insulin dependent diabetic subjects Horm. Metab. Res. 26 1992 106 108
    • (1992) Horm. Metab. Res. , vol.26 , pp. 106-108
    • Del Rio, G.1    Marrama, P.2    Della Casa, L.3
  • 41
    • 0019278898 scopus 로고
    • Increased integrated concentration of norepinephrine, epinephrine, aldosterone, and growth hormone in patients with uncontrolled juvenile diabetes mellitus
    • Z. Zadik, R. Kayne, and M. Kappy Increased integrated concentration of norepinephrine, epinephrine, aldosterone, and growth hormone in patients with uncontrolled juvenile diabetes mellitus Diabetes 29 1980 655 658
    • (1980) Diabetes , vol.29 , pp. 655-658
    • Zadik, Z.1    Kayne, R.2    Kappy, M.3
  • 42
    • 0017284855 scopus 로고
    • A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus
    • R.P. Robertson, J.B. Halter, and D.J. Porte A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus J. Clin. Invest. 57 1976 791 795
    • (1976) J. Clin. Invest. , vol.57 , pp. 791-795
    • Robertson, R.P.1    Halter, J.B.2    Porte, D.J.3
  • 44
    • 0002746443 scopus 로고    scopus 로고
    • Physiologic action of insulin
    • D. LeRoith S.I. Taylor J.M. Olefsky
    • P. Flakoli, M.G. Carlson, and A. Cherrington Physiologic action of insulin D. LeRoith S.I. Taylor J.M. Olefsky Diabetes Mellitus 1996 121 131
    • (1996) Diabetes Mellitus , pp. 121-131
    • Flakoli, P.1    Carlson, M.G.2    Cherrington, A.3
  • 45
    • 0025063027 scopus 로고
    • Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid
    • M.W. Schwartz, A.J. Sipols, and S.E. Kahn Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid Am. J. Physiol. 259 1990 E378 E383
    • (1990) Am. J. Physiol. , vol.259
    • Schwartz, M.W.1    Sipols, A.J.2    Kahn, S.E.3
  • 46
    • 0027361094 scopus 로고
    • Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain
    • G.D. Baura, D.M. Foster, and D. Porte Jr. Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain J. Clin. Invest. 92 1993 1824 1830
    • (1993) J. Clin. Invest. , vol.92 , pp. 1824-1830
    • Baura, G.D.1    Foster, D.M.2    Porte Jr., D.3
  • 47
    • 0035743089 scopus 로고    scopus 로고
    • Improving influence of insulin on cognitive functions in humans
    • W. Kern, A. Peters, and B. Fruehwald-Schultes Improving influence of insulin on cognitive functions in humans Neuroendocrinology 74 2001 270 280
    • (2001) Neuroendocrinology , vol.74 , pp. 270-280
    • Kern, W.1    Peters, A.2    Fruehwald-Schultes, B.3
  • 48
    • 0028817458 scopus 로고
    • Evidence that the brain of the conscious dog is insulin sensitive
    • S.N. Davis, C. Colburn, and R. Dobbins Evidence that the brain of the conscious dog is insulin sensitive J. Clin. Invest. 95 1995 593 602
    • (1995) J. Clin. Invest. , vol.95 , pp. 593-602
    • Davis, S.N.1    Colburn, C.2    Dobbins, R.3
  • 49
    • 0030903504 scopus 로고    scopus 로고
    • Brain of the conscious dog is sensitive to physiological changes in circulating insulin
    • S.N. Davis, B. Dunham, and K. Walmsley Brain of the conscious dog is sensitive to physiological changes in circulating insulin Am. J. Physiol. 272 1997 E567 E575
    • (1997) Am. J. Physiol. , vol.272
    • Davis, S.N.1    Dunham, B.2    Walmsley, K.3
  • 50
    • 0027507021 scopus 로고
    • The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension
    • E.A. Anderson, and A.L. Mark The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension Hypertension 21 1993 136 141
    • (1993) Hypertension , vol.21 , pp. 136-141
    • Anderson, E.A.1    Mark, A.L.2
  • 51
    • 0026801899 scopus 로고
    • Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM
    • M. Laakso, S.V. Edelman, and G. Brechtel Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM Diabetes 41 1992 1076 1083
    • (1992) Diabetes , vol.41 , pp. 1076-1083
    • Laakso, M.1    Edelman, S.V.2    Brechtel, G.3
  • 52
    • 0025763663 scopus 로고
    • Reduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in non-insulin-dependent diabetic subjects: Effects of insulin therapy
    • A.D. Baron, M. Laakso, and G. Brechtel Reduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in non-insulin-dependent diabetic subjects: effects of insulin therapy J. Clin. Invest. 87 1991 1186 1194
    • (1991) J. Clin. Invest. , vol.87 , pp. 1186-1194
    • Baron, A.D.1    Laakso, M.2    Brechtel, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.