Duration of α1-antichymotrypsin gene activation by interleukin-1 is determined by efficiency of inhibitor of nuclear factor κBα resynthesis in primary human astrocytes

Journal of Neurochemistry

Volumn 92, Issue 4, 2005, Pages 730-738

  Kiss, Daniel L ^a   Xu, Weili ^a,b   Gopalan, Sunita ^a,b   Buzanowska, Katarzyna ^a   Wilczynska, Katarzyna M ^a,b   Rydel, Russell E ^c   Kordula, Tomasz ^a,b  

^a CLEVELAND STATE UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c ELAN PHARMACEUTICALS   (United States)

Author keywords

1 antichymotrypsin; Astrocytes; Expression; Interleukin 1; Nuclear factor B

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; I KAPPA B ALPHA; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; PROTEIN P50; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; ASTROCYTE; CELL TYPE; COMPLEX FORMATION; GENE ACTIVATION; GENE EXPRESSION REGULATION; GLIA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REPORTER GENE; SIGNAL TRANSDUCTION;

ALPHA 1-ANTICHYMOTRYPSIN; ASTROCYTES; CELL LINE, TUMOR; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-1; NF-KAPPA B;

EID: 13644268433     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02900.x     Document Type: Article

References (49)

1. Abraham C. R., Selkoe D. J. and Potter H. (1988) Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52, 487-501.
2. Anest V., Hanson J. L., Cogswell P. C., Steinbrecher K. A., Strahl B. D. and Baldwin A. S. (2003) A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature 423, 659-663.
3. Arts J., Grimbergen J., Toet K. and Kooistra T. (1999) On the role of c-Jun in the induction of PAI-1 gene expression by phorbol ester, serum, and IL-1alpha in HepG2 cells. Arterioscler. Thromb. Vasc. Biol. 19, 39-46.
4. Baeuerle P. A. and Baltimore D. (1988) I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 242, 540-546.
5. Baumann H. and Gauldie J. (1994) The acute phase response [see comments]. Immunol Today 15, 74-80.
6. Bourke E., Kennedy E. J. and Moynagh P. N. (2000) Loss of Ikappa B-beta is associated with prolonged NF-kappa B activity in human glial cells. J. Biol. Chem. 275, 39 996-40 002.
7. Cardinaux J. R., Allaman I. and Magistretti P. J. (2000) Pro-inflammatory cytokines induce the transcription factors C/EBPbeta and C/EBPdelta in astrocytes. Glia 29, 91-97.
8. Cha-Molstad H., Agrawal A., Zhang D., Samols D. and Kushner I. (2000) The Rel family member P50 mediates cytokine-induced C-reactive protein expression by a novel mechanism. J. Immunol. 165, 4592-4597.
9. Chen L. F. and Greene W. C. (2003) Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J. Mol. Med. 81, 549-557.
10. Chen L. F., Mu Y. and Greene W. C. (2002) Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J. 21, 6539-6548.
11. Das S. and Potter H. (1995) Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron 14, 447-456.
12. Delegeane A. M., Ferland L. H. and Mellon P. L. (1987) Tissue-specific enhancer of the human glycoprotein hormone alpha- subunit gene: dependence on cyclic AMP-inducible elements. Mol. Cell. Biol. 7, 3994-4002.
13. Desterro J. M., Rodriguez M. S. and Hay R. T. (1998) SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol. Cell 2, 233-239.
14. DiDonato J. A., Hayakawa M., Rothwarf D. M., Zandi E. and Karin M. (1997) A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 388, 548-554.
15. Edbrooke M. R., Foldi J., Cheshire J. K., Li F., Faulkes D. J. and Woo P. (1991) Constitutive and NF-kappa B-like proteins in the regulation of the serum amyloid A gene by interleukin 1. Cytokine 3, 380-388.
16. Feinberg A. P. and Vogelstein B. (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13.
17. Fried M. and Crothers D. M. (1981) Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucl. Acids Res. 9, 6505-6525.
18. Ghirnikar R. S., Lee Y. L. and Eng L. F. (1998) Inflammation in traumatic brain injury: role of cytokines and chemokines. Neurochem. Res. 23, 329-340.
19. Ghosh S., May M. J. and Kopp E. B. (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260.
20. Gorman C. (1985) High efficiency gene transfer into mammalian cells, in DNA Cloning: a Practical Approach (Glover D., ed.), pp. 143-190. IRL Press.
21. Grimaldi L. M., Casadei V. M., Ferri C. et al. (2000) Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism [see comments]. Ann. Neurol. 47, 361-365.
22. Hay R. T., Vuillard L., Desterro J. M. and Rodriguez M. S. (1999) Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha. Philos. Trans. R. Soc. Lond. B Biol. Sci. 354, 1601-1609.
23. Higashitsuji H., Nagao T., Nonoguchi K., Fujii S., Itoh K. and Fujita J. (2002) A novel protein overexpressed in hepatoma accelerates export of NF-kappa B from the nucleus and inhibits p53-dependent apoptosis. Cancer Cell 2, 335-346.
24. Hwang S. R., Steineckert B., Kohn A., Palkovits M. and Hook V. Y. (1999) Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of ACT in hippocampus and liver. J. Biol. Chem. 274, 1821-1827.
25. Ito C. Y., Kazantsev A. G. and Baldwin A. S. Jr (1994) Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha. Nucl. Acids Res. 22, 3787-3792.
26. Karin M. and Ben-Neriah Y. (2000) Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu. Rev. Immunol. 18, 621-663.
27. Kasza A., Kiss D. L., Gopalan S., Xu W., Rydel R. E., Koj A. and Kordula T. (2002) Mechanism of plasminogen activator inhibitor-1 regulation by oncostatin M and interleukin-1 in human astrocytes. J. Neurochem. 83, 696-703.
28. Kiernan R., Bres V., Ng R. W., Coudart M. P., El Messaoudi S., Sardet C., Jin D. Y., Emiliani S. and Benkirane M. (2003) Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65. J. Biol. Chem. 278, 2758-2766.
29. Kordula T., Rydel R. E., Brigham E. F., Horn F., Heinrich P. C. and Travis J. (1998) Oncostatin M and the interleukin-6 and soluble interleukin-6 receptor complex regulate alpha1-antichymotrypsin expression in human cortical astrocytes. J. Biol. Chem. 273, 4112-4118.
30. Kordula T., Bugno M., Rydel R. E. and Travis J. (2000) Mechanism of interleukin-1- and tumor necrosis factor alpha-dependent regulation of the alpha 1-antichymotrypsin gene in human astrocytes. J. Neurosci. 20, 7510-7516.
31. Maniatis T. (1997) Catalysis by a multiprotein IkappaB kinase complex. Science 278, 818-819.
32. Nicoll J. A., Mrak R. E., Graham D. I. et al. (2000) Association of interleukin-1 gene polymorphisms with Alzheimer's disease [see comments]. Ann. Neurol. 47, 365-368.
33. Nilsson L. N., Bales K. R., DiCarlo G., Gordon M. N., Morgan D., Paul S. M. and Potter H. (2001) Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease. J. Neurosci. 21, 1444-1451.
34. Oakley F., Mann J., Ruddell R. G., Pickford J., Weinmaster G. and Mann D. A. (2003) Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP-J (CBF1) and its activator Notch1. J. Biol. Chem. 278, 24 359-24 370.
35. Rose-John S., Dietrich A. and Marks F. (1988) Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts. Gene 14, 465-471.
36. Ryo A., Suizu F., Yoshida Y., Perrem K., Liou Y. C., Wulf G., Rottapel R., Yamaoka S. and Lu K. P. (2003) Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol. Cell 12, 1413-1426.
37. Saccani S., Pantano S. and Natoli G. (2003) Modulation of NF-kappaB activity by exchange of dimers. Mol. Cell 11, 1563-1574.
38. Sakurai H., Suzuki S., Kawasaki N., Nakano H., Okazaki T., Chino A., Doi T. and Saiki I. (2003) Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J. Biol. Chem. 278, 36 916-36 923.
39. Sambrook J., Fritsch E. F. and Maniatis T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory.
40. Sawadogo M., Van Dyke M. W., Gregor P. D. and Roeder R. G. (1988) Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J. Biol. Chem. 263, 11 985-11 993.
41. Schmidt C., Peng B., Li Z., Sclabas G. M., Fujioka S., Niu J., Schmidt-Supprian M., Evans D. B., Abbruzzese J. L. and Chiao P. J. (2003) Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. Mol. Cell 12, 1287-1300.
42. Schrell U. M., Koch H. U., Marschalek R., Schrauzer T., Anders M., Adams E. and Fahlbusch R. (1998) Formation of autocrine loops in human cerebral meningioma tissue by leukemia inhibitor factor, interleukin-6, and oncostatin M: inhibition of meningioma cell growth in vitro by recombinant oncostatin M. J. Neurosurg. 88, 541-548.
43. Senftleben U., Cao Y., Xiao G. et al. (2001 ) Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 293, 1495-1499.
44. Sun S. C., Ganchi P. A., Ballard D. W. and Greene W. C. (1993) NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science 259, 1912-1915.
45. Suyang H., Phillips R., Douglas I. and Ghosh S. (1996) Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B. Mol. Cell. Biol. 16, 5444-5449.
46. Thompson J. E., Phillips R. J., Erdjument-Bromage H., Tempst P. and Ghosh S. (1995) I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B. Cell 80, 573-582.
47. Xiao G., Harhaj E. W. and Sun S. C. (2001) NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol. Cell 7, 401-409.
48. Yamamoto Y., Verma U. N., Prajapati S., Kwak Y. T. and Gaynor R. B. (2003) Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. Nature 423, 655-659.
49. Zhong H., May M. J., Jimi E. and Ghosh S. (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 9, 625-636.