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Volumn 3, Issue 3, 2004, Pages 92-98

Atazanavir - A once-daily HIV protease inhibitor that does not cause dyslipidemia in newly treated patients: Results from two randomized clinical trials

Author keywords

atazanavir; HIV protease inhibitors; hypercholesterolemia; hyperlipidemia; hypertriglyceridemia; nelfinavir

Indexed keywords

ATAZANAVIR; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OLIGOPEPTIDE; PROTEINASE INHIBITOR; PYRIDINE DERIVATIVE; TRIACYLGLYCEROL;

EID: 13644260227     PISSN: 15451097     EISSN: 15570886     Source Type: Journal    
DOI: 10.1177/154510970400300304     Document Type: Article
Times cited : (49)

References (46)
  • 1
    • 0034631873 scopus 로고    scopus 로고
    • Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: A 5-year cohort study
    • Tsiodras S, Mantzoros C, Hammer S, Samore M. Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: A 5-year cohort study. Arch Intern Med 2000 ; 160: 2050-2056. (Pubitemid 30437589)
    • (2000) Archives of Internal Medicine , vol.160 , Issue.13 , pp. 2050-2056
    • Tsiodras, S.1    Mantzoros, C.2    Hammer, S.3    Samore, M.4
  • 4
    • 0037217704 scopus 로고    scopus 로고
    • Dyslipidemia in the era of HIV protease inhibitors
    • DOI 10.1053/pcad.2003.4
    • Stein JH. Dyslipidemia in the era of HIV protease inhibitors. Prog Cardiovasc Dis 2003 ; 45: 293-304. (Pubitemid 36293025)
    • (2003) Progress in Cardiovascular Diseases , vol.45 , Issue.4 , pp. 293-304
    • Stein, J.H.1
  • 6
    • 0036404783 scopus 로고    scopus 로고
    • Evaluation and management of dyslipidemia in patients with HIV infection
    • DOI 10.1046/j.1525-1497.2002.20201.x
    • Green ML. Evaluation and management of dyslipidemia in patients with HIV infection. J Gen Intern Med 2002 ; 17: 797-810. (Pubitemid 35286246)
    • (2002) Journal of General Internal Medicine , vol.17 , Issue.10 , pp. 797-810
    • Green, M.L.1
  • 7
    • 1242324939 scopus 로고    scopus 로고
    • Favorable metabolic profile for tenofovir disoproxil fumarate (TDF) versus stavudine (d4T) when used in combination with lamivudine and efavirenz in antiretroviral naive patients: 96-week interim results
    • Staszewski S, Gallant JE, Pozniak AL, et al. Favorable metabolic profile for tenofovir disoproxil fumarate (TDF) versus stavudine (d4T) when used in combination with lamivudine and efavirenz in antiretroviral naive patients: 96-week interim results. 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment. July 13-16, 2003. Paris, France. (Abstract 562).
    • 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment
    • Staszewski, S.1    Gallant, J.E.2    Pozniak, A.L.3
  • 8
    • 0037685663 scopus 로고    scopus 로고
    • Prospective study of hyperlipidemia in ART-naive subjects taking combivir/abacavir (COM/ABC), COM/nelfinavir (NFV), or stavudine (d4T)/lamivudine (3TC)/NFV (ESS40002)
    • Kumar P, Rodriguez-French A, Thompson M, et al. Prospective study of hyperlipidemia in ART-naive subjects taking combivir/abacavir (COM/ABC), COM/nelfinavir (NFV), or stavudine (d4T)/lamivudine (3TC)/NFV (ESS40002). 9th Conference on Retroviruses and Opportunistic Infections. February 24-28, 2002. Seattle, WA, USA. (Abstract 33). Accessed March 8, 2004 from http://www.retroconference.org/2002/Abstract/13081.htm
    • 9th Conference on Retroviruses and Opportunistic Infections
    • Kumar, P.1    Rodriguez-French, A.2    Thompson, M.3
  • 10
    • 0037748566 scopus 로고    scopus 로고
    • Lipid changes in a randomized comparative trial of first-line antiretroviral therapy with regimens containing either nevirapine alone, efavirenz alone or both drugs combined, together with stavudine and lamivudine (2NN Study)
    • van Leth F, Phanuphak P, Gazzard B, et al. Lipid changes in a randomized comparative trial of first-line antiretroviral therapy with regimens containing either nevirapine alone, efavirenz alone or both drugs combined, together with stavudine and lamivudine (2NN Study). 10th Conference on Retroviruses and Opportunistic Infections. February 10-14, 2003. Boston, MA, USA. (Poster 752). Accessed March 8, 2004 from http://www.retroconference.org/2003/Abstract/ Abstract.aspx?AbstractID=97
    • 10th Conference on Retroviruses and Opportunistic Infections
    • Van Leth, F.1    Phanuphak, P.2    Gazzard, B.3
  • 12
    • 0033527333 scopus 로고    scopus 로고
    • Myocardial infarction in HIV-infected men receiving protease inhibitors [6]
    • Flynn TE, Bricker LA. Myocardial infarction in HIV-infected men receiving protease inhibitors. Ann Intern Med 1999 ; 131: 548. (Pubitemid 29482406)
    • (1999) Annals of Internal Medicine , vol.131 , Issue.7 , pp. 548
    • Flynn, T.E.1    Bricker, L.A.2
  • 14
    • 17444376929 scopus 로고    scopus 로고
    • Association between protease inhibitors and increased cardiovascular risk: A systematic review
    • (Abstract 56)
    • Rhew D, Kim M, Bernal M, Aguilar D, Iloeje U, Goetz MB. Association between protease inhibitors and increased cardiovascular risk: A systematic review. Antivir Ther 2002 ; 7: L38. (Abstract 56).
    • (2002) Antivir Ther , vol.7 , pp. 38
    • Rhew, D.1    Kim, M.2    Bernal, M.3    Aguilar, D.4    Iloeje, U.5    Goetz, M.B.6
  • 16
    • 17844387799 scopus 로고    scopus 로고
    • Protease inhibitors may increase risk of cardiovascular disease in HIV-infected patients
    • Iloeje U, Yuan Y, Tuomari A, et al. Protease inhibitors may increase risk of cardiovascular disease in HIV-infected patients. 10th Conference on Retroviruses and Opportunistic Infections. February 10-14, 2003. Boston, MA, USA. (Poster 746). Accessed: May 6, 2004 from http://www.retroconference.org/ 2003/Abstract/Abstract.aspx?AbstractID=630
    • 10th Conference on Retroviruses and Opportunistic Infections
    • Iloeje, U.1    Yuan, Y.2    Tuomari, A.3
  • 17
    • 1642403331 scopus 로고    scopus 로고
    • Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men
    • DOI 10.1097/00002030-200311210-00010
    • Mary-Krause M, Cotte L, Simon A, et al. Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men. AIDS 2003 ; 17: 2479-2486. (Pubitemid 38393320)
    • (2003) AIDS , vol.17 , Issue.17 , pp. 2479-2486
    • Mary-Krause, M.1    Cotte, L.2    Simon, A.3    Partisani, M.4    Costagliola, D.5
  • 18
    • 0037456351 scopus 로고    scopus 로고
    • Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection
    • DOI 10.1056/NEJMoa022048
    • Bozzette SA, Ake CF, Tam HK, Chang SW, Louis TA. Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. N Engl J Med 2003 ; 348: 702-710. (Pubitemid 36237039)
    • (2003) New England Journal of Medicine , vol.348 , Issue.8 , pp. 702-710
    • Bozzette, S.A.1    Ake, C.F.2    Tam, H.K.3    Chang, S.W.4    Louis, T.A.5
  • 19
    • 0035902493 scopus 로고    scopus 로고
    • Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction
    • Stein JH, Klein MA, Bellehumeur JL, et al. Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation 2001 ; 104: 257-262. (Pubitemid 32666944)
    • (2001) Circulation , vol.104 , Issue.3 , pp. 257-262
    • Stein, J.H.1    Klein, M.A.2    Bellehumeur, J.L.3    McBride, P.E.4    Wiebe, D.A.5    Otvos, J.D.6    Sosman, J.M.7
  • 21
    • 0032564571 scopus 로고    scopus 로고
    • Severe coronary artery disease in a young HIV-infected man with no cardiovascular risk factor who was treated with indinavir [1]
    • Karmochkine M, Raguin G. Severe coronary artery disease in a young HIV-infected man with no cardiovascular risk factor who was treated with indinavir. AIDS 1998 ; 12: 2499. (Pubitemid 28558610)
    • (1998) AIDS , vol.12 , Issue.18 , pp. 2499
    • Karmochkine, M.1    Raguin, G.2
  • 22
    • 1842474732 scopus 로고    scopus 로고
    • Progression of Atherosclerosis as Assessed by Carotid Intima-Media Thickness in Patients with HIV Infection
    • DOI 10.1161/01.CIR.0000124480.32233.8A
    • Hsue PY, Lo JC, Franklin A, et al. Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. Circulation 2004 ; 109: 1603-1608. (Pubitemid 38451715)
    • (2004) Circulation , vol.109 , Issue.13 , pp. 1603-1608
    • Hsue, Y.1    Lo, J.C.2    Franklin, A.3    Bolger, A.F.4    Martin, J.N.5    Deeks, S.G.6    Waters, D.D.7
  • 23
    • 0037234238 scopus 로고    scopus 로고
    • Results of a phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects
    • Sanne I, Piliero P, Squires K, Thiry A, Schnittman S. Results of a phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects. J Acquir Immune Defic Syndr 2003 ; 32: 18-29. (Pubitemid 36091481)
    • (2003) Journal of Acquired Immune Deficiency Syndromes , vol.32 , Issue.1 , pp. 18-29
    • Sanne, I.1    Piliero, P.2    Squires, K.3    Thiry, A.4    Schnittman, S.5
  • 24
    • 1642465026 scopus 로고    scopus 로고
    • Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-Week results
    • DOI 10.1097/00002030-200312050-00007
    • Murphy RL, Sanne I, Cahn P, et al. Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in antiretroviral-naive subjects: 48-week results. AIDS 2003 ; 17: 2603-2614. (Pubitemid 38402338)
    • (2003) AIDS , vol.17 , Issue.18 , pp. 2603-2614
    • Murphy, R.L.1    Sanne, I.2    Cahn, P.3    Phanuphak, P.4    Percival, L.5    Kelleher, T.6    Giordano, M.7
  • 25
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection Evaluation Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001 ; 285: 2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 27
    • 0037013037 scopus 로고    scopus 로고
    • Switching to zidovudine plus lamivudine plus abacavir maintains viral suppression in patients with high viral load before antiretroviral therapy: A retrospective clinical cohort analysis [3]
    • DOI 10.1097/00002030-200205030-00022
    • Moyle GJ, Gazzard BG. Switching to zidovudine plus lamivudine plus abacavir maintains viral suppression in patients with high viral load before antiretroviral therapy: A retrospective clinical cohort analysis. AIDS 2002 ; 16: 1086-1087. (Pubitemid 34499439)
    • (2002) AIDS , vol.16 , Issue.7 , pp. 1086-1087
    • Moyle, G.J.1    Gazzard, B.G.2
  • 28
    • 0034457426 scopus 로고    scopus 로고
    • Preliminary guidelines for the evaluation and management of dyslipidemia in adults infected with human immunodeficiency virus and receiving antiretroviral therapy: Recommendations of the adult AIDS clinical trial group cardiovascular disease focus group
    • DOI 10.1086/317429
    • Dubé MP, Sprecher D, Henry WK, et al. Preliminary guidelines for the evaluation and management of dyslipidemia in adults infected with human immunodeficiency virus and receiving antiretroviral therapy: Recommendations of the Adult AIDS Clinical Trial Group Cardiovascular Disease Focus Group. Clin Infect Dis 2000 ; 31: 1216-1224. (Pubitemid 32295453)
    • (2000) Clinical Infectious Diseases , vol.31 , Issue.5 , pp. 1216-1224
    • Dube, M.P.1    Sprecher, D.2    Henry, W.K.3    Aberg, J.A.4    Torriani, F.J.5    Hodis, H.N.6    Schouten, J.7    Levin, J.8    Myers, G.9    Zackin, R.10    Nevin, T.11    Currier, J.S.12
  • 29
    • 0042832397 scopus 로고    scopus 로고
    • Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)-infected adults receiving antiretroviral therapy: Recommendations of the HIV Medicine Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group
    • DOI 10.1086/378131
    • Dubé MP, Stein JH, Aberg JA, et al. Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)-infected adults receiving antiretroviral therapy: Recommendations of the HIV Medical Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group. Clin Infect Dis 2003 ; 37: 613-627. (Pubitemid 37100800)
    • (2003) Clinical Infectious Diseases , vol.37 , Issue.5 , pp. 613-627
    • Dube, M.P.1    Stein, J.H.2    Aberg, J.A.3    Fichtenbaum, C.J.4    Gerber, J.G.5    Tashima, K.T.6    Henry, W.K.7    Currier, J.S.8    Sprecher, D.9    Glesby, M.J.10
  • 31
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 1994 ; 344: 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 32
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995 ; 333: 1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 35
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998 ; 339: 1349-1357.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 36
    • 13944257981 scopus 로고    scopus 로고
    • Treatment of HIV-associated dyslipidemia: A time trend analysis 1998-2001
    • (Abstract 42)
    • Iloeje UH, Yu-Isenberg KS, Ventura EP, Tuomari AV. Treatment of HIV-associated dyslipidemia: A time trend analysis 1998-2001. Antivir Ther 2002 ; 7: L29. (Abstract 42).
    • (2002) Antivir Ther , vol.7 , pp. 29
    • Iloeje, U.H.1    Yu-Isenberg, K.S.2    Ventura, E.P.3    Tuomari, A.V.4
  • 39
    • 0033873920 scopus 로고    scopus 로고
    • Hyperlipidemia associated with HIV protease inhibitor use: Pathophysiology, prevalence, risk factors and treatment
    • Penzak SR, Chuck SK. Hyperlipidemia associated with HIV protease inhibitor use: Pathophysiology, prevalence, risk factors and treatment. Scand J Infect Dis 2000 ; 32: 111-123. (Pubitemid 30599192)
    • (2000) Scandinavian Journal of Infectious Diseases , vol.32 , Issue.2 , pp. 111-123
    • Penzak, S.R.1    Chuck, S.K.2
  • 41
    • 0038046900 scopus 로고    scopus 로고
    • Incidence of hyperlipidaemia in a cohort of 212 HIV-infected patients receiving a protease inhibitor-based antiretroviral therapy
    • DOI 10.1016/S0924-8579(03)00100-6
    • Calza L, Manfredi R, Farneti B, Chiodo F. Incidence of hyperlipidaemia in a cohort of 212 HIV-infected patients receiving a protease inhibitor-based antiretroviral therapy. Int J Antimicrob Agents 2003 ; 22: 54-59. (Pubitemid 36808718)
    • (2003) International Journal of Antimicrobial Agents , vol.22 , Issue.1 , pp. 54-59
    • Calza, L.1    Manfredi, R.2    Farneti, B.3    Chiodo, F.4
  • 42
    • 84864211521 scopus 로고    scopus 로고
    • Favourable increases in high-density lipoprotein cholesterol (HDL-C) concentrations in chronic HIV-infected therapy naive subjects receiving 908/R QD in the SOLO study
    • Horban A, Staszewski S, Walmsley S, Pierone G, Sexton A, Stark T. Favourable increases in high-density lipoprotein cholesterol (HDL-C) concentrations in chronic HIV-infected therapy naive subjects receiving 908/R QD in the SOLO study. 9th European AIDS Conference (EACS). 1st EACS Resistance & Pharmacology Workshop. October 25-29, 2003. Warsaw, Poland. (Abstract F8/3). Accessed June 16, 2004 from http://www.aegis.com/conferences/eacs2003/41. html
    • 9th European AIDS Conference (EACS). 1st EACS Resistance & Pharmacology Workshop
    • Horban, A.1    Staszewski, S.2    Walmsley, S.3    Pierone, G.4    Sexton, A.5    Stark, T.6
  • 44
    • 3242686642 scopus 로고    scopus 로고
    • Once-daily vs. twice-daily lopinavir/ritonavir in antiretroviral-naive patients: 48-week results
    • Gathe J, Podzamczer D, Johnson M, et al. Once-daily vs. twice-daily lopinavir/ritonavir in antiretroviral-naive patients: 48-week results. 11th Conference on Retroviruses and Opportunistic Infections. February 8-11, 2004. San Francisco, CA, USA. (Abstract 570). Accessed June 17, 2004 from http://www.retroconference.org/2004/cd/Abstract/570.htm
    • 11th Conference on Retroviruses and Opportunistic Infections
    • Gathe, J.1    Podzamczer, D.2    Johnson, M.3
  • 45
    • 0037661234 scopus 로고    scopus 로고
    • Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: A randomized comparative pilot trial
    • DOI 10.1097/00002030-200306130-00008
    • Haas DW, Zala C, Schrader S, et al. Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: A randomized comparative pilot trial. AIDS 2003 ; 17: 1339-1349. (Pubitemid 36819848)
    • (2003) AIDS , vol.17 , Issue.9 , pp. 1339-1349
    • Haas, D.W.1    Zala, C.2    Schrader, S.3    Piliero, P.4    Jaeger, H.5    Nunes, D.6    Thiry, A.7    Schnittman, S.8    Sension, M.9
  • 46
    • 84864274449 scopus 로고    scopus 로고
    • Safety assessment of patients receiving atazanavir (ATV) with ritonavir (RTV), ATV with saquinavir (SQV), or lopinavir (LPV)/RTV: 48-week results from BMS A1424-045
    • Clotet B, Lazzarin A, Grinsztejn B, Lichtenstein K, Sankoh S, Wilber R. Safety assessment of patients receiving atazanavir (ATV) with ritonavir (RTV), ATV with saquinavir (SQV), or lopinavir (LPV)/RTV: 48-week results from BMS A1424-045. 13th International Symposium on HIV & Emerging Infectious Diseases. June 3-5, 2004. Toulon, France. (Abstract PP 4.57). Accessed June 14, 2004 from http://www.isheid.com/faq-286.htm
    • 13th International Symposium on HIV & Emerging Infectious Diseases
    • Clotet, B.1    Lazzarin, A.2    Grinsztejn, B.3    Lichtenstein, K.4    Sankoh, S.5    Wilber, R.6


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