Sequential loss of myelin proteins during Wallerian degeneration in the human spinal cord

Brain

Volumn 128, Issue 2, 2005, Pages 356-364

  Buss, Armin ^a,h   Pech, K ^b   Merkler, D ^b   Kakulas, B A ^c   Martin, D ^d,e   Schoenen, J ^e   Noth, J ^a   Schwab, M E ^f,g   Brook, G A ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d CHU SART TILMAN   (Belgium)

^e UNIVERSITY OF LIÈGE   (Belgium)

^f UNIVERSITY OF ZURICH   (Switzerland)

^g ETH ZURICH   (Switzerland)

^h NONE   (Germany)

Author keywords

Myelin; NOGO A; Oligodendrocyte; Spinal cord; Wallerian degeneration

Indexed keywords

MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN PROTEIN; PROTEIN NOGO A;

ADULT; AGED; ARTICLE; AUTOPSY; BRAIN INFARCTION; CONTROLLED STUDY; CONVALESCENCE; DEATH; DISEASE COURSE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MYELIN SHEATH; NERVE DEGENERATION; NERVE FIBER MEMBRANE; NERVE FIBER REGENERATION; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPINAL CORD ATROPHY; SPINAL CORD INJURY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASTROCYTES; CELL COUNT; CEREBRAL INFARCTION; HUMANS; MIDDLE AGED; MYELIN PROTEINS; NERVE FIBERS; OLIGODENDROGLIA; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTORS; WALLERIAN DEGENERATION;

EID: 13544265330     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh355     Document Type: Article

References (40)

1. Aldskogius H, Kozlova EN. Central neuron-glial and glial-glial interactions following axon injury. Prog Neurobiol 1998; 55: 1-26.
2. Amar AP, Levy ML. Pathogenesis and pharmacological strategies for mitigating secondary damage in acute spinal cord injury. Neurosurgery 1999; 44: 1027-40.
3. Beattie MS, Harrington AW, Lee R, Young Kim J, Boyce SL, Longo FM, et al. ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron 2002; 36: 375-86.
4. Becerra JL, Puckett WR, Hiester ED, Quencer RM, Marcillo AE, Post MJ, et al. MR-pathologic comparisons of wallerian degeneration in spinal cord injury. AJNR Am J Neuroradiol 1995; 16: 125-33.
5. Breithaupt C, Schubart A, Zander H, Skerra A, Huber R, Linington C, Jacob U. Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proc Natl Acad Sci USA 2003; 100: 9446-51.
6. Bruck W. The role of macrophages in Wallerian degeneration. Brain Pathol 1997; 7: 741-52.
7. Buss A, Schwab ME. Sequential loss of myelin proteins during Wallerian degeneration in the rat spinal cord. Glia 2003; 42: 424-32.
8. Buss A, Brook GA, Kakulas B, Martin D, Franzen R, Schoenen J, et al. Gradual loss of myelin and formation of an astrocytic scar during Wallerian degeneration in the human spinal cord. Brain 2004; 127: 34-44.
9. Buss A, Sellhaus B, Noth J, Schwab ME, Brook GA. Expression pattern of NOGO-A protein in the human nervous system. Acta Neuropathol. In press 2005.
10. Coleman M, Perry V. Axon pathology in neurological disease: a neglected therapeutic target. Trends Neurosci 2002; 25: 532.
11. Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 1997; 3: 73-6.
12. Dusart I, Schwab ME. Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur J Neurosci 1994; 6: 712-24.
13. Emery E, Aldana P, Bunge MB, Puckett W, Srinivasan A, Keane RW, et al. Apoptosis after traumatic human spinal cord injury. J Neurosurg 1998; 89: 911-20.
14. Gabriel JM, Erne B, Bernasconi L, Tosi C, Probst A, Landmann L, et al. Confocal microscopic localization of anti-myelin-associated glycoprotein autoantibodies in a patient with peripheral neuropathy initially lacking a detectable IgM gammopathy. Acta Neuropathol 1998; 95: 540-6.
15. George R, Griffin JW. Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model. Exp Neurol 1994a; 129: 225-36.
16. George R, Griffin JW. The proximo-distal spread of axonal degeneration in the dorsal columns of the rat. J Neurocytol 1994b; 23: 657-67.
17. George EB, Glass JD, Griffin JW. Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels. J Neurosci 1995; 15: 6445-52.
18. Griffin JW, George R, Lobato C, Tyor WR, Yan LC, Glass JD. Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination. J Neuroimmunol 1992; 40: 153-65.
19. Linnington C, Webb M, Woodhams PL. A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody. J Neuroimmunol 1984; 6: 387-96.
20. Liu BP, Fournier A, GrandPre T, Strittmatter SM. Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor. Science 2002; 297: 1190-3.
21. Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 1999; 122: 2279-95.
22. Mautes AE, Weinzierl MR, Donovan F, Noble LJ. Vascular events after spinal cord injury: contribution to secondary pathogenesis. Phys Ther 2000; 80: 673-87.
23. Miklossy J, Van der Loos H. The long-distance effects of brain lesions: visualization of myelinated pathways in the human brain using polarizing and fluorescence microscopy. J Neuropathol Exp Neurol 1991; 50: 1-15.
24. Mukhopadhyay G, Doherty P, Walsh FS, Cracker PR, Filbin MT. A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron 1994; 13: 757-67.
25. Oertle T, van der Haar ME, Bandtlow CE, Robeva A, Burfeind P, Buss A, Hubor AB, Simonen M, Schnell L, Brosamle C, Kaupmann K, Vallon R, Schwab ME. Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. J Neurosci 2003; 23: 5393-406.
26. Schlaepfer WW. Calcium-induced degeneration of axoplasm in isolated segments of rat peripheral nerve. Brain Res 1974; 69: 203-15.
27. Schmitt AB, Brook GA, Buss A, Nacimiento W, Noth J, Kreutzberg GW. Dynamics of microglial activation in the spinal cord after cerebral infarction are revealed by expression of MHC class II antigen. Neuropathol Appl Neurobiol 1998; 24: 167-76.
28. Schwab ME. Nogo and axon regeneration. Curr Opin Neurobiol 2004; 14: 118-24.
29. Schwab ME, Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 1996; 76: 319-70.
30. Shamash S, Reichert F, Rotshenker S. The cytokine network of Wallerian degeneration: tumor necrosis factor-alpha, interleukin-1 alpha, and interleukin-lbeta. J Neurosci 2002; 22: 3052-60.
31. Shuman SL, Bresnahan JC, Beattie MS. Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. J Neurosci Res 1997; 50: 798-808.
32. Simonen M, Pedersen V, Weinmann O, Schnell L, Buss A, Ledermann B, et al. Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury. Neuron 2003; 38: 201-11.
33. Stoll G, Jander S. The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 1999; 58: 233-47.
34. Stoll G, Muller HW. Nerve injury, axonal degeneration and neural regeneration: basic insights. Brain Pathol 1999; 9: 313-25.
35. Stoll G, Trapp BD, Griffin JW. Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression. J Neurosci 1989; 9: 2327-35.
36. Waller A. Experiments on the section of glossopharyngeal and hypoglossal nerves of the frog and observations of the alternatives produced thereby in the structure of their primitive fibres. Phil Trans R Soc Lond 1850; 140: 423.
37. Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, et al. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 2002; 417: 941-4.
38. Waxman SG, Ransom BR, Stys PK. Non-synaptic mechanisms of Ca(2+)-mediated injury in CNS white matter. Trends Neurosci 1991; 14: 461-8.
39. Wroblewski R, Roomans GM, Kozlova EN. Effects of dorsal root transection on morphology and chemical composition of degenerating nerve fibers and reactive astrocytes in the dorsal funiculus. Exp Neurol 2000; 164: 236-45.
40. Zhai Q, Wang J, Kim A, Liu Q, Watts R, Hoopfer E, et al. Involvement of the ubiquitin-proteasome system in the early stages of Wallerian degeneration. Neuron 2003; 39: 217-25.