Diversity-oriented solid-phase synthesis and biological evaluation of oligonucleotide hairpins as HIV-1 RT RNase H inhibitors

Nucleic Acids Research

Volumn 32, Issue 21, 2004, Pages 6164-6175

  Hannousch, Rami N ^a,b   Min, Kyung Lyum ^a   Damha, Masad J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; DNA; NUCLEASE; NUCLEIC ACID; NUCLEOTIDE; OLIGONUCLEOTIDE; RIBONUCLEASE; RNA; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; DRUG CLASSIFICATION; DRUG CONFORMATION; DRUG POTENCY; DRUG RESISTANCE; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENE LIBRARY; GENETIC VARIABILITY; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; IN VITRO STUDY; MOLECULAR BIOLOGY; NONHUMAN; NUCLEIC ACID SYNTHESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; RETROVIRUS; SENSITIVITY ANALYSIS; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION; THERMOSTABILITY; VIRUS GENOME; VIRUS REPLICATION;

ANTI-HIV AGENTS; BASE SEQUENCE; ENDORIBONUCLEASES; GENE LIBRARY; HIV-1 REVERSE TRANSCRIPTASE; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 13444283855     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh948     Document Type: Article

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