Proteolipid Protein Gene

Myelin Biology and Disorders

Volumn 1, Issue , 2004, Pages 401-420

  Hudson, Lynn D ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 13444275722     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012439510-7/50069-3     Document Type: Chapter

References (129)

1. Anderson T.J., Montague P., Nadon N., Nave K.A., Griffiths I.R. Modification of Schwann cell phenotype with Plp transgenes: Evidence that the PLP and DM20 isoproteins are targeted to different cellular domains. J Neurosci Res. 1997, 50:13-22.
2. Armstrong R., Kim J., Hudson L.D. Expression of Myelin transcription factor 1 (Myt1), a "Zinc-Finger" DNA binding protein, in developing oligodendrocytes. Glia 1995, 14:303-321.
3. Baumgartner B.G., Deppe A., Rettenberger G., Leeb T., Hameister H., Brenig B. Molecular analysis of the porcine proteolipid protein (PLP) gene. Mamm Genome 1999, 10(9):895-899.
4. Baumrind N.L., Parkinson D., Wayne D.B., Heuser J.E., Pearlman A.L. EMA: A developmentally regulated cell-surface glycoprotein of CNS neurons that is concentrated at leading edge of growth cones. Dev Dyn. 1992, 194(4):311-325.
5. Barres B.A., Lazar M.A., Raff M.C. A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oliogdendrocyte development. Development 1994, 120:1097-1108.
6. Bellefroid E.J., Bourguignon C., Hollemann T., Ma Q., Anderson D.J., Kintner C., Pieler T. X-Myt1, a Xenopus C2HC-Type zinc finger protein with a regulatory function in neuronal differentiation. Cell 1996, 87:1191-1202.
7. Berndt J., Kim J., Hudson L.D. Cis regulatory elements required for expression of the myelin proteolipid protein gene. J. Biol. Chem. 1992, 267:14730-14737.
8. Berndt J.A., Kim J.G., Tosic M., Kim C., Hudson L.D. The transcriptional regulator Yin Yang 1 activates the myelin PLP gene. J. Neurochem. 2001, 77:935-942.
9. Billon N., Tokumoto Y., Forrest D., Raff M. Role of thyroid hormone receptors in timing oligodendrocyte differentiation. Dev Biol. 2001, 235(1):110-120.
10. Bizzozero O.A., Bixler H.A., Davis J.D., Espinosa A., Messier A.M. Chemical deacylation reduces the adhesive properties of proteolipid protein and leads to decompaction of the myelin sheath. J Neurochem. 2001, 76(4):1129-1141.
11. Bizzozero O.A., Lees M.B. Fatty acid composition of myelin proteolipid protein during vertebrate evolution. Neurochem Res. 1999, 24(2):269-274.
12. Bizzozero O.A., Leyba J., Nunez D.J. Characterization of proteolipid protein fatty acylesterase from rat brain myelin. J Biol Chem. 1992, 267(11):7886-7894.
13. Bizzozero O.A., Malkoski S.P., Mobarak C., Bixler H.A., Evans J.E. Mass-spectrometric analysis of myelin proteolipids reveals new features of this family of palmitoylated membrane proteins. J Neurochem. 2002, 81(3):636-645.
14. Bizzozero O.A., McGarry J.F., Lees M.B. Autoacylation of myelin proteolipid protein with acyl coenzyme A. Biol Chem. 1987, 262(28):13550-13557.
15. Bogazzi F., Hudson L.D., Nikodem V.M. A novel heterodimerization partner for thyroid hormone receptor. J. Biol. Chem. 1994, 269:11683-11686.
16. Boison D., Bussow H., D'Urso D., Muller H.W., Stoffel W. Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths. J Neurosci. 1995, 15(8):5502-5513.
17. Boison D., Stoffel W. Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice. Proc Natl Acad Sci U S A 1994, 91:11709-11713. (24).
18. Bongarzone E.R., Campagnoni C.W., Kampf K., Jacobs E.C., Handley V.W., Schonmann V., Campagnoni A.T. Identification of a new exon in the myelin proteolipid protein gene encoding novel protein isoformsthat are restricted to the somata of oligodendrocytes and neurons. J Neurosci. 1999, 19(19):8349-8357.
19. Boucher S.E.M., Cypher M.A., Carlock L.R., Skoff R.P. Proteolipid protein gene modulates viability and phenotype of neurons. J. Neurosci. 2002, 22:1772-1783.
20. Britsch S., Goerich D.E., Riethmacher D., Peirano R.I., Rossner M., Nave K.A., Birchmeier C., Wegner M. The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 2001, 15(1):66-78.
21. Campagnoni C.W., Garbay B., Micevych P., Pribyl T., Kampf K., Handley V.W., Campagnoni A.T. DM20 mRNA splice product of the myelin proteolipid protein gene is expressed in the murine heart. J Neurosci Res. 1992, 33(1):148-155.
22. Chandross K.J., Champagne B., Auble K., Hudson L.D. Tracking oligodendrocytes during development and regeneration. Microscopy Res. Tech. 2001, 52:766-777.
23. de Cozar M., Lucas M., Monreal J. Ionophoric properties of the proteolipid apoprotein from bovine brain myelin. Biochem Int 1987, 14:833-841.
24. Dickinson P.J., Griffiths I.R., Barrie J.M., Kyriakides E., Pollock G.F., Barnett S.C. Expression of the dm-20 isoform of the plp gene in olfactory nerve ensheathing cells: Evidence from developmental studies. J Neurocytol. 1997, 26(3):181-189.
25. Diehl H.J., Schaich M., Budzinski R.M., Stoffel W. Individual exons encode the integral membrane domains of human myelin proteolipid protein. Proc Natl Acad Sci U S A 1986, 83:9807-9811. (24).
26. Folch J., Lees M.B. Proteolipids, a new type of tissue lipoproteins: Their isolation from brain. J. Biol. Chem. 1951, 191:807-817.
27. Franz T., Waehneldt T.V., Neuhoff V., Wachtler K. Central nervous system myelin proteins and glycoproteins in vertebrates: A phylogenetic study. Brain Res. 1981, 226(1-2):245-258.
28. Fuss B., Mallon B., Phan T., Ohlemeyer C., Kirchhoff F., Nishiyama A., Macklin W.B. Purification and analysis of in vivo-differentiated oligodendrocytes expressing the green fluorescent protein. Dev Biol. 2000, 218(2):259-274.
29. Geltner D., Kitagawa K., Yoshida M. Remarkable diversity of proteolipid proteins in fish. J Neurosci Res. 1998, 54(2):289-295.
30. Gow A. Redefining the lipophilin family of proteolipid proteins. J Neurosci Res. 1997, 50(5):659-664.
31. Gow A., Friedrich V.L., Lazzarini R.A. Intracellular transport and sorting of the oligodendrocyte transmembrane proteolipid protein. J Neurosci Res. 1994, 37(5):563-573.
32. Gow A., Friedrich V.L., Lazzarini R.A. Many naturally occurring mutations of myelin proteolipid protein impair its intracellular transport. J Neurosci Res. 1994, 37(5):574-583.
33. Gow A., Gragerov A., Gard A., Colman D.R., Lazzarini R.A. Conservation of topology, but not conformation, of the proteolipid proteins of the myelin sheath. J Neurosci. 1997, 17(1):181-199.
34. Gow A., Lazzarini R.A. A cellular mechanism governing the severity of Pelizaeus-Merzbacher disease. Nat Genet. 1996, 13(4):422-428.
35. Gow A., Southwood C.M., Lazzarini R.A. Disrupted proteolipid protein trafficking results in oligodendrocyte apoptosis in an animal model of Pelizaeus-Merzbacher disease. J Cell Biol. 1998, 140(4):925-934.
36. Granneman J., Skoff R., Yang X. Member of the peroxisome proliferator-activated receptor family of transcription factors is differentially expressed by oliogdendrocytes. J. Neurosci Res. 1998, 51:563-573.
37. Greer J.M., Dyer C.A., Pakaski M., Symonowicz C., Lees M.B. Orientation of myelin proteolipid protein in the oligodendrocyte cell membrane. Neurochem Res. 1996, 21(4):431-440.
38. Griffiths I.R., Dickinson P., Montague P. Expression of the proteolipid protein gene in glial cells of the post-natal peripheral nervous system of rodents. Neuropathol Appl Neurobiol. 1995, 21(2):97-110.
39. Griffiths I.R., Klugmann M., Anderson T.J., Yool D., Thomson C.E., Schwab M.H., Schneider A., Zimmermann F., McCulloch M.C., Nadon N.L., Nave K.-A. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science 1998, 280:1610-1613.
40. Griffiths I.R., Mitchell L.S., McPhilemy K., Morrison S., Kyriakides E., Barrie J.A. Expression of myelin protein genes in Schwann cells. J Neurocytol 1989, 18(3):345-352.
41. Gupta S.K., Pringle J., Poduslo J.F., Mezei C. Levels of proteolipid protein mRNAs in peripheral nerve are not under stringent axonal control. J Neurochem. 1991, 56(5):1754-1762.
42. Helynck G., Bang L., Nussbaum J.-L., Picken D., Skalidis G., Trifilieff E., Van Dorsselaer A., Seta P., Sandeaux R., Gavach E., Heitz F., Simon D., Spach G. Brain proteolipids: Isolation, purification and effect on ionic permeability of membranes. Eur. J. Biochem 1983, 133:689-695.
43. Hudson L.D., Friedrich V., Behar T., Dubois-Dalcq M., Lazzarini R.A. The initial events in myelin synthesis: Orientation of proteolipid protein in the plasma membrane of cultured oligodendrocytes. J. Cell Biol. 1989, 109:717-727.
44. Ikenaka K., Furuichi T., Iwasaki Y., Moriguchi A., Okano H., Mikoshiba K. Myelin proteolipid protein gene structure and its regulation of expression in normal and jimpy mutant mice. J. Mol Biol. 1988, 199:587-596.
45. Ikenaka K., Kagawa T., Mikoshiba K. Selective expression of DM-20, an alternatively spliced myelin proteolipid protein gene product, in developing nervous system and in nonglial cells. J Neurochem. 1992, 58(6):2248-2253.
46. Inouye H., Kirschner D.A. Orientation of proteolipid protein in myelin: Comparison of models with X-ray diffraction measurements. Dev. Neurosci. 1989, 11:81-89.
47. Janz R., Stoffel W. Characterization of a brain-specific Sp1-like activity interacting with an unusual binding site within the myelin proteolipid protein promoter. Biol. Chem. Hoppe Seyler 1993, 374:507-517.
48. Jiang H., Duchala C.S., Awatramani R., Shumas S., Carlock L., Kamholz J., Garbern J., Scherer S.S., Shy M.E., Macklin W.B. Proteolipid protein mRNA stability is regulated by axonal contact in the rodent peripheral nervous system. J. Neurobiol. 2000, 44:7-19.
49. Jung M., Sommer I., Schachner M., Nave K.-A. Monoclonal antibody O10 defines a conformationally sensitive cell-surface epitope of proteolipid protein (PLP): Evidence that PLP misfolding underlies dysmyelination in transgenic mice. J. Neurosci. 1996, 16:7920-7929.
50. Kahan I., Moscarello M.A. Identification of membrane-embedded domains of lipophilin from human myelin. Biochem. 1985, 24:538-554.
51. Kamholz J., Sessa M., Scherer S., Vogelbacker H., Mokuno K., Baron P., Wrabetz L., Shy M., Pleasure D. Structure and expression of proteolipid protein in the peripheral nervous system. J Neurosci Res. 1992, 31(2):231-244.
52. 2-HC Finger that recognizes a glial-specific gene. Molecular Cell Biol. 1992, 12:5632-5639.
53. Kim J.G., Armstrong R.C., Berndt J.A., Kim N.W., Hudson L.D. A secreted DNA-binding protein that is translated through an internal ribosome entry site (IRES). Mol. Cell. Neurosci. 1998, 12:119-140.
54. Kim J.G., Armstrong R.C., Robinsky A., Agoston D.v., Wiese C., Nagle J., Hudson L.D. Cloning, mapping and expression of a neuronal zinc finger gene closely related to Myelin Transcription Factor 1 (Myt1) of the oligodendrocyte lineage. J. Neurosci. Res. 1997, 50:272-290.
55. Kitagawa K., Sinoway M.P., Yang C., Gould R.M., Colman D.R. A proteolipid protein gene family: Expression in sharks and rays and possible evolution from anancestral gene encoding a pore-forming polypeptide. Neuron. 1993, 11(3):433-448.
56. Klugmann M., Schwab M.H., Puhlhofer A., Schneider A., Zimmermann F., Griffiths I.R., Nave K.A. Assembly of CNS myelin in the absence of proteolipid protein. Neuron. 1997, 18(1):59-70.
57. Knapp P.E., Bartlett W.P., Williams L.A., Yamada M., Ikenaka K., Skoff R.P. Programmed cell death without DNA fragmentation in the jimpy mouse: Secreted factors can enhance survival. Cell Death Differ 1999, 6:136-145.
58. Konola J.T., Yamamura T., Tyler B., Lees M.B. Orientation of the myelin proteolipid protein C-terminus in oligodendroglial membranes. Glia 1992, 5:112-121.
59. Kurihara T., Sakuma M., Gojobori T. Molecular evolution of myelin proteolipid protein. Biochem Biophys Res Commun. 1997, 237(3):559-561.
60. Lagenaur C., Kunemund V., Fischer G., Fushiki S., Schachner M. Monoclonal M6 antibody interferes with neurite extension of cultured neurons. J Neurobiol. 1992, 23(1):71-188.
61. Lees M., Brostoff S.L. Proteins of myelin. Myelin 1984, 197-224. Plenum Press, New York. 2nd ed. P. Morell (Ed.).
62. Lees M.B., Sakura J.D., Sapirstein VS, Curatolo W. Structure and function of proteolipids in myelin and non-myelin membranes. Biochim Biophys Acta 1979, 559(2-3):209-230.
63. Lepage P., Helynck G., Chu J.Y., Luu B., Sorokine O., Trifilieff E., Van Dorsselaer A. Purification and characterization of minor brain proteolipids: Use of fast atom bombardment-masspectrometry for peptide sequencing. Biochimie. 1986, 68(5):669-686.
64. Li A.H.Y., Silverstein B., Leone M.G., Giacomelli S., Cheng C.Y. Cerebrin-50, a human cerebrospinal fluid protein whose mRNA is present in multiple tissues but predominantly expressed in lymphoblastoid cells and the brain. Biochem. Mol. Biol. 1995, 35:135-144.
65. Li S., Dobretsova A., Kokorina N.A., Wight P.A. Repression of myelin proteolipid protein gene expression is mediated through both general and cell type-specific negative regulatory elements in nonexpressing cells. J Neurochem. 2002, 82(1):159-171.
66. Macklin W.B., Campagnoni C.W., Deininger PL., Gardinier M.V. Structure and expression of the mouse myelin proteolipid protein gene. J Neurosci Res. 1987, 18(3):383-394.
67. Mallon B.S., Shick H.E., Kidd G.J., Macklin W.B. Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development. J Neurosci. 2002, 22(3):876-885.
68. McLaughlin M., Hunter D.J., Thomson C.E., Yool D., Kirkham D., Freer A.A., Griffiths I.R. Evidence for possible interactions between PLP and DM20 within the myelin sheath. Glia. 2002, 39(1):31-36.
69. Mi Z.P., Weng W., Hankin M.H., Narayanan V., Lagenaur C.F. Maturational changes in cell surface antigen expression in the mouse retina and optic pathway. Brain Res Dev Brain Res. 1998, 106(1-2):145-154.
70. Milner R.J., Lai C., Nave K-A., Lenoir D., Ogata J., Sutcliffe J.G. Nucleotide sequences of two mRNAs for rat brain myelin proteolipid protein. Cell 1985, 42:931-939.
71. Nadon N.L. Aberrant dendritic growth in central nervous system white matter induced by a mutant proteolipid protein transgene. J. Comp. Neurol. 2000, 416:262-268.
72. Nadon N.L., Arnheiter H., Hudson L.D. A combination of PLP and DM20 transgenes promotes partial myelination in the jimpy mouse. J Neurochem. 1994, 63(3):822-833.
73. Nadon N.L., West M. Myelin proteolipid protein: Function in myelin structure is distinct from its role in oligodendrocyte development. Dev Neurosci. 1998, 20(6):533-5339.
74. Nakao J., Yamada M., Kagawa T., Kim S.U., Miyao Y., Shimizu K., Mikoshiba K., Ikenaka K. Expression of proteolipid protein gene is directly associated with secretion of a factor influencing oligodendrocyte development. J. Neurochem. 1995, 64:2396-2403.
75. Nave K.A., Lemke G. Induction of the myelin proteolipid protein (PLP) gene in C6 glioblastoma cells: functional analysis of the PLP promoter. J Neurosci. 1991, 11(10):3060-3069.
76. Olinsky S., Loop B.T., DeKosky A., Ripepi B., Weng W., Cummins J., Wenger S.L., Yan Y., Lagenaur C., Narayanan V. Chromosomal mapping of the human M6 genes. Genomics. 1996, 33(3):532-536.
77. Peirano R.I., Wegner M. The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences. Nucleic Acids Res. 2000, 28(16):3047-3055.
78. Peters J.M., Lee S.S.T, Li W., Ward J.M., Gavrilova O., Everett C., Reitman M.L., Hudson L.D., Gonzalez F.J. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor β (δ). Mol. Cell. Biol. 2000, 20:5119-5128. 2000.
79. Pham-Dinh D., Birling M.C., Roussel G., Dautigny A., Nussbaum J.L. Proteolipid DM-20 predominates over PLP in peripheral nervous system. Neuroreport. 1991, 2(2):89-92.
80. Popot J.L., Phan Dinh D., Dautigny A. Major myelin proteolipid: The 4-alpha-helix topology. J. Membr. Biol. 1991, 120:233-246.
81. Pribyl T.M., Campagnoni C.W., Kampf K., Kashima T., Handley V.W., McMahon J., Campagnoni A.T. Expression of the myelin proteolipid protein gene in the human fetal thymus. J Neuroimmunol. 1996, 67(2):125-130.
82. Puckett C., Hudson L., Ono K., Friedrich V., Benecke J., Dubois-Dalcq M., Lazzarini R.A. Myelin-specific proteolipid protein is expressed in myelinating Schwann cells but is not incorporated into myelin sheaths. J Neurosci Res. 1987, 18(4):511-518.
83. Rosenbluth J., Stoffel W., Schiff R. Myelin structure in proteolipid protein (PLP)-null mouse spinal cord. J Comp Neurol. 1996, 371(2):336-344.
84. Ross N.W., Braun P.E. Acylation in vitro of the myelin proteolipid protein and comparison with acylation in vivo: Acylation of a cysteine occurs nonenzymatically. Neurosci Res. 1988, 21(1):35-44.
85. Scherer S.S., Vogelbacker H.H., Kamholz J. Axons modulate the expression of proteolipid protein in the CNS. J Neurosci Res. 1992, 32(2):138-148.
86. Schindler P., Luu B., Sorokine O., Trifilieff E., Van Dorsselaer A. Developmental study of proteolipids in bovine brain: A novel proteolipid and DM20 appear before proteolipid protein (PLP) during myelination. J. Neurochem. 1990, 55:2079-2086.
87. Schliess F., Stoffel W. Evolution of the myelin integral membrane proteins of the central nervous system. Biol Chem Hoppe Seyler. 1991, 372(9):865-874.
88. Schneider A., Montague P., Griffiths I., Fanarraga M., Kennedy P., Brophy P., Nave K.A. Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene. Nature 1992, 358(6389):758-761.
89. Sheetz M.P., Baumrind N.L., Wayne D.B., Pearlman A.L. Concentration of membrane antigens by forward transport and trapping in neuronal growth cones. Cell. 1990, 61(2):231-241.
90. Shi Y.J., Lee J.S., Galvin K.M. Everything you have ever wanted to know about Yin Yang 1. Biochim. Biophys. Acta 1997, 1332:F49-F66.
91. Shimokawa N., Miura M. Rhombex-29, a novel gene of the PLP/DM20-M6 family cloned from rat medulla oblongata by differential display. J Neurosci Res. 2000, 62(1):1-8.
92. Simons M., Kramer E.M., Macchi P., Rathke-Hartlieb S., Trotter J., Nave K.-A., Schulz J.B. Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: Implications for Pelizaeus-Merzbacher disease. J Cell Biol. 2002, 157:327-336.
93. Simons M., Kramer E.M., Thiele C., Stoffel W., Trotter J. Assembly of myelin by association of proteolipid protein with cholesterol-andgalactosylceramide-rich membrane domains. J Cell Biol. 2000, 151(1):143-154.
94. Sinoway M.P., Kitagawa K., Timsit S., Hashim G.A., Colman D.R. Proteolipid protein interactions in transfectants: Implications for myelin assembly. J Neurosci Res. 1994, 37(5):551-562.
95. Sobel R.A., Greer J.M., Isaac J., Fondren G., Lees M.B. Immunolocalization of proteolipid protein peptide 103-116 in myelin. J. Neurosci. Res. 1994, 37:36-43.
96. Southwood C., Gow A. Molecular pathways of oligodendrocyte apoptosis revealed by mutations in the proteolipid proteingene. Microsc Res Tech. 2001, 52(6):700-708.
97. Spassky N., Goujet-Zalc C., Parmantier E., Olivier C., Martinez S., Ivanova A., Ikenaka K., Macklin W., Cerruti, Zalc B., Thomas J.L. Multiple restricted origin of oligodendrocytes. J Neurosci. 1998, 18(20):8331-8843.
98. Sporkel O., Uschkureit T., Bussow H., Stoffel W. Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: Myelination and development. Glia 2002, 37(1):19-30.
99. Stecca B., Southwood C.M., Gragerov A., Kelley K.A., Friedrich V.L., Gow A. The evolution of lipophilin genes from invertebrates to tetrapods: DM-20 cannot replace proteolipid protein in CNS myelin. J Neurosci. 2000, 20(11):4002-4010.
100. Stoffel W., Hillen H., Giersiefen H. Structure and molecular arrangement of proteolipid protein of central nervous system myelin. Proc Natl Acad Sci USA 1984, 81:5012-5016. (16).
101. Stoffel W., Subkowski T., Jander S. Topology of proteolipid protein in the myelin membrane of central nervous system. A study usingantipeptide antibodies. Biol Chem Hoppe Seyler. 1989, 370(2):165-176.
102. Stolt C.C., Rehberg S., Ader M., Lommes P., Riethmacher D., Schachner M., Bartsch U., Wegner M. Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002, 16(2):165-170.
103. Thomas J.L., Spassky N., Perez Villegas E.M., Olivier C., Cobos I., Goujet-Zalc C., Martinez S., Zalc B. Spatiotemporal development of oligodendrocytes in the embryonic brain. J Neurosci Res. 2000, 59(4):47146-47147.
104. Thomson C.E., Montague P., Jung M., Nave K.A., Griffiths I.R. Phenotypic severity of murine Plp mutants reflects in vivo and in vitro variations in transport of PLP isoproteins. Glia 1997, 20(4):322-332.
105. Timsit S.G., Bally-Cuif L., Colman D.R., Zalc B. DM-20 mRNA is expressed during the embryonic development of the nervous system of the mouse. J Neurochem. 1992, 58(3):1172-1175.
106. Timsit S., Martinez S., Allinquant B., Peyron F., Puelles L., Zalc B. Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression. J Neurosci. 1995, 15(2):1012-1024.
107. Ting-Beall H.P., Lees M.B., Robertson J.D. Interactions of Folch-Lees proteolipid apoprotein with planar lipid bilayers. J. Membr. Biol. 1979, 51:33-46.
108. Uschkureit T., Sporkel O., Bussow H., Stoffel W. Rumpshaker-Like Proteolipid Protein (PLP) ratio in a mouse model with unperturbed structural and functional integrity of the myelin sheath and axons in the central nervous system. Glia 2001, 35:63-71.
109. Venkatesh B., Erdmann M.V., Brenner S. Molecular synapomorphies resolve evolutionary relationships of extant jawed vertebrates. Proc Natl Acad Sci U S A 2001, 98:11382-11387. (20).
110. Vouyiouklis D.A., Barrie J.A., Griffiths I.R., Thomson C.E. A proteolipid protein-specific pre-mRNA (Ppm-1) contains intron 3 and is up-regulated duringmyelination in the CNS. J Neurochem 2000, 74(3):940-948.
111. Vouyiouklis D.A., Werner H., Griffiths I.R., Stewart G.J., Armin-Nave K., Thomson C.E. Molecular cloning and transfection studies of M6b-2, a novel splice variant of a member of the PLP-DM20/M6 gene family. J Neurosci Res. 1998, 52(6):633-640.
112. Waehneldt T.V., Malotka J., Karin N.J., Matthieu J.M. Phylogenetic examination of vertebrate central nervous system myelin proteins by electro-immunoblotting. Neurosci Lett. 1985, 57(1):97-102.
113. Wahle S., Stoffel W. Cotranslational integration of myelin proteolipid protein (PLP) into the membrane of endoplasmic reticulum: Analysis of topology by glycosylation scanning and protease domain protection assay. Glia. 1998, 24(2):226-235.
114. Weimbs T., Stoffel W. Proteolipid protein (PLP) of CNS myelin: Positions of free, disulfide-bonded, and fatty acidthioester-linked cysteine residues and implications for the membrane topology of PLP. Biochemistry. 1992, 31(49):12289-12296.
115. Weimbs T., Stoffel W. Topology of CNS myelin proteolipid protein: Evidence for the nonenzymatic glycosylation of extracytoplasmic domains in normal and diabetic animals. Biochemistry. 1994, 33(34):10408-10415.
116. Werner H., Dimou L., Klugmann M., Pfeiffer S., Nave K.A. Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes. Mol Cell Neurosci. 2001, 18(6):593-605.
117. Wight P.A., Dobretsova A. The first intron of the myelin proteolipid protein gene confers cell type-specific expression by a transcriptional repression mechanism in non-expressing cell types. Gene. 1997, 201(1-2):111-117.
118. Wight P.A., Dobretsova A., Macklin W.B. Regulation of murine myelin proteolipid protein gene expression. J Neurosci Res. 1997, 50(6):917-927.
119. Wight P.A., Duchala C.S., Readhead C., Macklin W.B. A myelin proteolipid protein-LacZ fusion protein is developmentally regulated and targeted to the membrane in transgenic mice. J Cell Biol. 1993, 123(2):443-454.
120. Witt A., Brady ST Unwrapping new layers of complexity in axon/glial relationships. Glia 2000, 29(2):112-117.
121. Yamada M., Ivanova A., Yamaguchi Y., Lees M.B., Ikenaka K. Proteolipid protein gene product can be secreted and exhibit biological activity during earlydevelopment. J Neurosci. 1999, 19(6):2143-2151.
122. Yamaguchi Y., Ikenaka K., Niinobe M., Yamada H., Mikoshiba K. Myelin proteolipid protein (PLP), but not DM-20, is an inositol hexakisphosphate-finding protein. J Biol Chem. 1996, 271(44):27838-27846.
123. Yan Y., Lagenaur C., Narayanan V. Molecular cloning of M6: Identification of a PLP/DM20 gene family. Neuron. 1993, 11(3):423-431.
124. Yan Y., Naryanan V., Lagenaur C. Expression of members of the proteolipid protein gene family in the developing murine central nervous system. J. Comp. Neurol. 1996, 370:465-478.
125. Yool D., Klugmann M., Barrie J.A., McCulloch M.C., Nave K.A., Griffiths I.R. Observations on the structure of myelin lacking the major proteolipid protein. Neuropathol Appl Neurobiol. 2002, 28(1):75-78.
126. Yool D.A., Klugmann M., McLaughlin M., Vouyiouklis D.A., Dimou L., Barrie J.A., McCulloch M.C., Nave K.A., Griffiths I.R. Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons. J Neurosci Res. 2001, 63(2):151-164.
127. Yoshida M., Colman D.R. Parallel evolution and coexpression of the proteolipid proteins and protein zero in vertebrate myelin. Neuron. 1996, 16(6):1115-1126.
128. Yoshida M., Shan W.S., Colman D.R. Conserved and divergent expression patterns of the proteolipid protein gene family in the amphibiancentral nervous system. J Neurosci Res. 1999, 57(1):13-22.
129. Yu W.P., Collarini E.J., Pringle N.P., Richardson W.D. Embryonic expression of myelin genes: Evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube. Neuron. 1994, 12(6):1353-1362.