메뉴 건너뛰기




Volumn 38, Issue 2, 2005, Pages 257-265

Pioglitazone, a peroxisome proliferator-activated receptor γ activator, ameliorates experimental autoimmune myocarditis by modulating Th1/Th2 balance

Author keywords

Cytokine; Helper T cell; Myocarditis; Peroxisome proliferator activated receptor ; Pioglitazone

Indexed keywords

CARDIAC MYOSIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 13444274720     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.11.010     Document Type: Article
Times cited : (53)

References (46)
  • 1
    • 0027223695 scopus 로고
    • Characterization of T cells infiltrating the heart in rats with experimental autoimmune myocarditis. Their similarity to extrathymic T cells in mice and the site of proliferation
    • H. Hanawa, M. Tsuchida, Y. Matsumoto, H. Watanabe, T. Abo, and H. Sekikawa Characterization of T cells infiltrating the heart in rats with experimental autoimmune myocarditis. Their similarity to extrathymic T cells in mice and the site of proliferation J. Immunol. 150 1993 5682 5695
    • (1993) J. Immunol. , vol.150 , pp. 5682-5695
    • Hanawa, H.1    Tsuchida, M.2    Matsumoto, Y.3    Watanabe, H.4    Abo, T.5    Sekikawa, H.6
  • 2
    • 0025939319 scopus 로고
    • Characteristics of giant cells and factors related to the formation of giant cells in myocarditis
    • M. Kodama, Y. Matsumoto, M. Fujiwara, S.S. Zhang, H. Hanawa, and E. Itoh Characteristics of giant cells and factors related to the formation of giant cells in myocarditis Circ. Res. 69 1991 1042 1050
    • (1991) Circ. Res. , vol.69 , pp. 1042-1050
    • Kodama, M.1    Matsumoto, Y.2    Fujiwara, M.3    Zhang, S.S.4    Hanawa, H.5    Itoh, E.6
  • 4
    • 0034936956 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha relates to the recruitment of inflammatory cells in myosin-induced autoimmune myocarditis in rats
    • T. Toyozaki, T. Saito, H. Shiraishi, Y. Tsukamoto, H. Takano, and T. Nagai Macrophage inflammatory protein-1alpha relates to the recruitment of inflammatory cells in myosin-induced autoimmune myocarditis in rats Lab. Invest. 81 2001 929 936
    • (2001) Lab. Invest. , vol.81 , pp. 929-936
    • Toyozaki, T.1    Saito, T.2    Shiraishi, H.3    Tsukamoto, Y.4    Takano, H.5    Nagai, T.6
  • 6
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • W.J. Karpus, N.W. Lukacs, B.L. McRae, R.M. Strieter, S.L. Kunkel, and S.D. Miller An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis J. Immunol. 155 1995 5003 5010
    • (1995) J. Immunol. , vol.155 , pp. 5003-5010
    • Karpus, W.J.1    Lukacs, N.W.2    McRae, B.L.3    Strieter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 7
    • 0029791412 scopus 로고    scopus 로고
    • PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
    • K. Schoonjans, J. Peinado-Onsurbe, A.M. Lefebvre, R.A. Heyman, M. Briggs, and S. Deeb PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene EMBO J. 15 1996 5336 5348
    • (1996) EMBO J. , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.M.3    Heyman, R.A.4    Briggs, M.5    Deeb, S.6
  • 8
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • J. Berger, and D.E. Moller The mechanisms of action of PPARs Annu. Rev. Med. 53 2002 409 435
    • (2002) Annu. Rev. Med. , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 9
    • 0034730794 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes
    • H. Takano, T. Nagai, M. Asakawa, T. Toyozaki, T. Oka, and I. Komuro Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes Circ. Res. 87 2000 596 602
    • (2000) Circ. Res. , vol.87 , pp. 596-602
    • Takano, H.1    Nagai, T.2    Asakawa, M.3    Toyozaki, T.4    Oka, T.5    Komuro, I.6
  • 11
    • 0037066014 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo
    • M. Asakawa, H. Takano, T. Nagai, H. Uozumi, H. Hasegawa, and N. Kubota Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo Circulation 105 2002 1240 1246
    • (2002) Circulation , vol.105 , pp. 1240-1246
    • Asakawa, M.1    Takano, H.2    Nagai, T.3    Uozumi, H.4    Hasegawa, H.5    Kubota, N.6
  • 12
    • 0037699442 scopus 로고    scopus 로고
    • The role of PPARgamma-dependent pathway in the development of cardiac hypertrophy
    • H. Takano, H. Hasegawa, T. Nagai, and I. Komuro The role of PPARgamma-dependent pathway in the development of cardiac hypertrophy Drugs Today (Barc) 39 2003 347 357
    • (2003) Drugs Today (Barc) , vol.39 , pp. 347-357
    • Takano, H.1    Hasegawa, H.2    Nagai, T.3    Komuro, I.4
  • 13
    • 0037058874 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction
    • T. Shiomi, H. Tsutsui, S. Hayashidani, N. Suematsu, M. Ikeuchi, and J. Wen Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction Circulation 106 2002 3126 3132
    • (2002) Circulation , vol.106 , pp. 3126-3132
    • Shiomi, T.1    Tsutsui, H.2    Hayashidani, S.3    Suematsu, N.4    Ikeuchi, M.5    Wen, J.6
  • 14
    • 0034533048 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors are expressed in human cultured mast cells: A possible role of these receptors in negative regulation of mast cell activation
    • H. Sugiyama, T. Nonaka, T. Kishimoto, K. Komoriya, K. Tsuji, and T. Nakahata Peroxisome proliferator-activated receptors are expressed in human cultured mast cells: a possible role of these receptors in negative regulation of mast cell activation Eur. J. Immunol. 30 2000 3363 3370
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3363-3370
    • Sugiyama, H.1    Nonaka, T.2    Kishimoto, T.3    Komoriya, K.4    Tsuji, K.5    Nakahata, T.6
  • 15
    • 0034777941 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells
    • P. Gosset, A.S. Charbonnier, P. Delerive, J. Fontaine, B. Staels, and J. Pestel Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells Eur. J. Immunol. 31 2001 2857 2865
    • (2001) Eur. J. Immunol. , vol.31 , pp. 2857-2865
    • Gosset, P.1    Charbonnier, A.S.2    Delerive, P.3    Fontaine, J.4    Staels, B.5    Pestel, J.6
  • 16
    • 0036901274 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets
    • M. Okada, S.F. Yan, and D.J. Pinsky Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets FASEB J. 16 2002 1861 1868
    • (2002) FASEB J. , vol.16 , pp. 1861-1868
    • Okada, M.1    Yan, S.F.2    Pinsky, D.J.3
  • 17
    • 0038825370 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme a reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats
    • H. Hasegawa, R. Yamamoto, H. Takano, M. Mizukami, M. Asakawa, and T. Nagai 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats J. Mol. Cell Cardiol. 35 2003 953 960
    • (2003) J. Mol. Cell Cardiol. , vol.35 , pp. 953-960
    • Hasegawa, H.1    Yamamoto, R.2    Takano, H.3    Mizukami, M.4    Asakawa, M.5    Nagai, T.6
  • 18
    • 0034037198 scopus 로고    scopus 로고
    • Strain difference in rats with experimental giant cell myocarditis
    • K. Shioji, C. Kishimoto, Y. Nakayama, and S. Sasayama Strain difference in rats with experimental giant cell myocarditis Jpn. Circ. J. 64 2000 283 286
    • (2000) Jpn. Circ. J. , vol.64 , pp. 283-286
    • Shioji, K.1    Kishimoto, C.2    Nakayama, Y.3    Sasayama, S.4
  • 19
    • 0033168993 scopus 로고    scopus 로고
    • Decreased expression of Th2 type cytokine mRNA contributes to the lack of allergic bronchial inflammation in aged rats
    • K. Ide, H. Hayakawa, T. Yagi, A. Sato, Y. Koide, and A. Yoshida Decreased expression of Th2 type cytokine mRNA contributes to the lack of allergic bronchial inflammation in aged rats J. Immunol. 163 1999 396 402
    • (1999) J. Immunol. , vol.163 , pp. 396-402
    • Ide, K.1    Hayakawa, H.2    Yagi, T.3    Sato, A.4    Koide, Y.5    Yoshida, A.6
  • 20
    • 1542315613 scopus 로고    scopus 로고
    • Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells
    • M. Matsubara, S. Masaki, K. Ohmori, A. Karasawa, and K. Hasegawa Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells Biochem. Pharmacol. 67 2004 1315 1326
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 1315-1326
    • Matsubara, M.1    Masaki, S.2    Ohmori, K.3    Karasawa, A.4    Hasegawa, K.5
  • 21
    • 0028302285 scopus 로고
    • Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 alpha by inflammatory granuloma fibroblasts
    • N.W. Lukacs, S.W. Chensue, R.E. Smith, R.M. Strieter, K. Warmington, and C. Wilke Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 alpha by inflammatory granuloma fibroblasts Am. J. Pathol. 144 1994 711 718
    • (1994) Am. J. Pathol. , vol.144 , pp. 711-718
    • Lukacs, N.W.1    Chensue, S.W.2    Smith, R.E.3    Strieter, R.M.4    Warmington, K.5    Wilke, C.6
  • 22
    • 0032794139 scopus 로고    scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by MIP-1alpha and MCP-1 naked DNA vaccines
    • S. Youssef, G. Wildbaum, and N. Karin Prevention of experimental autoimmune encephalomyelitis by MIP-1alpha and MCP-1 naked DNA vaccines J. Autoimmun. 13 1999 21 29
    • (1999) J. Autoimmun. , vol.13 , pp. 21-29
    • Youssef, S.1    Wildbaum, G.2    Karin, N.3
  • 23
    • 0032972793 scopus 로고    scopus 로고
    • Hemodynamic basis for the acute cardiac effects of troglitazone in isolated perfused rat hearts
    • M. Shimoyama, K. Ogino, Y. Tanaka, T. Ikeda, and I. Hisatome Hemodynamic basis for the acute cardiac effects of troglitazone in isolated perfused rat hearts Diabetes 48 1999 609 615
    • (1999) Diabetes , vol.48 , pp. 609-615
    • Shimoyama, M.1    Ogino, K.2    Tanaka, Y.3    Ikeda, T.4    Hisatome, I.5
  • 24
    • 0037453063 scopus 로고    scopus 로고
    • Glitazones and heart failure: Critical appraisal for the clinician
    • C.H. Wang, R.D. Weisel, P.P. Liu, P.W. Fedak, and S. Verma Glitazones and heart failure: critical appraisal for the clinician Circulation 107 2003 1350 1354
    • (2003) Circulation , vol.107 , pp. 1350-1354
    • Wang, C.H.1    Weisel, R.D.2    Liu, P.P.3    Fedak, P.W.4    Verma, S.5
  • 25
    • 0035993207 scopus 로고    scopus 로고
    • PPAR and immune system--what do we know?
    • X. Zhang, and H.A. Young PPAR and immune system--what do we know? Int. Immunopharmacol. 2 2002 1029 1044
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 1029-1044
    • Zhang, X.1    Young, H.A.2
  • 26
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • M. Ricote, A.C. Li, T.M. Willson, C.J. Kelly, and C.K. Glass The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 391 1998 79 82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 27
    • 10144226439 scopus 로고    scopus 로고
    • 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways
    • S. Boyault, M.A. Simonin, A. Bianchi, E. Compe, B. Liagre, and D. Mainard 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways FEBS Lett. 501 2001 24 30
    • (2001) FEBS Lett. , vol.501 , pp. 24-30
    • Boyault, S.1    Simonin, M.A.2    Bianchi, A.3    Compe, E.4    Liagre, B.5    Mainard, D.6
  • 28
    • 0036314839 scopus 로고    scopus 로고
    • Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size
    • N.S. Wayman, Y. Hattori, M.C. McDonald, H. Mota-Filipe, S. Cuzzocrea, and B. Pisano Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size FASEB J. 16 2002 1027 1040
    • (2002) FASEB J. , vol.16 , pp. 1027-1040
    • Wayman, N.S.1    Hattori, Y.2    McDonald, M.C.3    Mota-Filipe, H.4    Cuzzocrea, S.5    Pisano, B.6
  • 29
    • 0242516069 scopus 로고    scopus 로고
    • Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs
    • Y. Xu, L. Lu, C. Greyson, J. Lee, M. Gen, and K. Kinugawa Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs Diabetes 52 2003 1187 1194
    • (2003) Diabetes , vol.52 , pp. 1187-1194
    • Xu, Y.1    Lu, L.2    Greyson, C.3    Lee, J.4    Gen, M.5    Kinugawa, K.6
  • 30
    • 0029797142 scopus 로고    scopus 로고
    • Persistent expression of cytokine in the chronic stage of viral myocarditis in mice
    • T. Shioi, A. Matsumori, and S. Sasayama Persistent expression of cytokine in the chronic stage of viral myocarditis in mice Circulation 94 1996 2930 2937
    • (1996) Circulation , vol.94 , pp. 2930-2937
    • Shioi, T.1    Matsumori, A.2    Sasayama, S.3
  • 31
    • 0035876287 scopus 로고    scopus 로고
    • Relationship between tumor necrosis factor-alpha production and oxidative stress in the failing hearts of patients with dilated cardiomyopathy
    • T. Tsutamoto, A. Wada, T. Matsumoto, K. Maeda, N. Mabuchi, and M. Hayashi Relationship between tumor necrosis factor-alpha production and oxidative stress in the failing hearts of patients with dilated cardiomyopathy J. Am. Coll. Cardiol. 37 2001 2086 2092
    • (2001) J. Am. Coll. Cardiol. , vol.37 , pp. 2086-2092
    • Tsutamoto, T.1    Wada, A.2    Matsumoto, T.3    Maeda, K.4    Mabuchi, N.5    Hayashi, M.6
  • 32
    • 0038221307 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: Consequences for the immune response
    • V. Angeli, H. Hammad, B. Staels, M. Capron, B.N. Lambrecht, and F. Trottein Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response J. Immunol. 170 2003 5295 5301
    • (2003) J. Immunol. , vol.170 , pp. 5295-5301
    • Angeli, V.1    Hammad, H.2    Staels, B.3    Capron, M.4    Lambrecht, B.N.5    Trottein, F.6
  • 33
    • 0142210174 scopus 로고    scopus 로고
    • Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: Involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor
    • S.W. Chung, B.Y. Kang, and T.S. Kim Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor Mol. Pharmacol. 64 2003 1169 1179
    • (2003) Mol. Pharmacol. , vol.64 , pp. 1169-1179
    • Chung, S.W.1    Kang, B.Y.2    Kim, T.S.3
  • 34
    • 0141922040 scopus 로고    scopus 로고
    • Inhibition of IgE-production by peroxisome proliferator-activated receptor ligands
    • R. Ruhl, A. Dahten, F.J. Schweigert, U. Herz, and M. Worm Inhibition of IgE-production by peroxisome proliferator-activated receptor ligands J. Invest. Dermatol. 121 2003 757 764
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 757-764
    • Ruhl, R.1    Dahten, A.2    Schweigert, F.J.3    Herz, U.4    Worm, M.5
  • 35
    • 0036743165 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis
    • L.J. Saubermann, A. Nakajima, K. Wada, S. Zhao, Y. Terauchi, and T. Kadowaki Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis Inflamm. Bowel Dis. 8 2002 330 339
    • (2002) Inflamm. Bowel Dis. , vol.8 , pp. 330-339
    • Saubermann, L.J.1    Nakajima, A.2    Wada, K.3    Zhao, S.4    Terauchi, Y.5    Kadowaki, T.6
  • 36
    • 0037087324 scopus 로고    scopus 로고
    • Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors
    • R. Cunard, M. Ricote, D. DiCampli, D.C. Archer, D.A. Kahn, and C.K. Glass Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors J. Immunol. 168 2002 2795 2802
    • (2002) J. Immunol. , vol.168 , pp. 2795-2802
    • Cunard, R.1    Ricote, M.2    Dicampli, D.3    Archer, D.C.4    Kahn, D.A.5    Glass, C.K.6
  • 37
    • 0033595261 scopus 로고    scopus 로고
    • Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
    • J.T. Huang, J.S. Welch, M. Ricote, C.J. Binder, T.M. Willson, and C. Kelly Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase Nature 400 1999 378 382
    • (1999) Nature , vol.400 , pp. 378-382
    • Huang, J.T.1    Welch, J.S.2    Ricote, M.3    Binder, C.J.4    Willson, T.M.5    Kelly, C.6
  • 39
    • 0035806905 scopus 로고    scopus 로고
    • Protection against autoimmune myocarditis by gene transfer of interleukin-10 by electroporation
    • K. Watanabe, M. Nakazawa, K. Fuse, H. Hanawa, M. Kodama, and Y. Aizawa Protection against autoimmune myocarditis by gene transfer of interleukin-10 by electroporation Circulation 104 2001 1098 1100
    • (2001) Circulation , vol.104 , pp. 1098-1100
    • Watanabe, K.1    Nakazawa, M.2    Fuse, K.3    Hanawa, H.4    Kodama, M.5    Aizawa, Y.6
  • 40
    • 0032103328 scopus 로고    scopus 로고
    • Recombinant murine interleukin-12 facilitates induction of cardiac myosin-specific type 1 helper T cells in rats
    • Y. Okura, K. Takeda, S. Honda, H. Hanawa, H. Watanabe, and M. Kodama Recombinant murine interleukin-12 facilitates induction of cardiac myosin-specific type 1 helper T cells in rats Circ. Res. 82 1998 1035 1042
    • (1998) Circ. Res. , vol.82 , pp. 1035-1042
    • Okura, Y.1    Takeda, K.2    Honda, S.3    Hanawa, H.4    Watanabe, H.5    Kodama, M.6
  • 41
    • 0036546185 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
    • C. Natarajan, and J.J. Bright Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation Genes Immun. 3 2002 59 70
    • (2002) Genes Immun. , vol.3 , pp. 59-70
    • Natarajan, C.1    Bright, J.J.2
  • 42
    • 0344153921 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis
    • C. Natarajan, G. Muthian, Y. Barak, R.M. Evans, and J.J. Bright Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis J. Immunol. 171 2003 5743 5750
    • (2003) J. Immunol. , vol.171 , pp. 5743-5750
    • Natarajan, C.1    Muthian, G.2    Barak, Y.3    Evans, R.M.4    Bright, J.J.5
  • 43
    • 0038460253 scopus 로고    scopus 로고
    • PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages
    • J.S. Welch, M. Ricote, T.E. Akiyama, F.J. Gonzalez, and C.K. Glass PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages Proc. Natl. Acad. Sci. USA 100 2003 6712 6717
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6712-6717
    • Welch, J.S.1    Ricote, M.2    Akiyama, T.E.3    Gonzalez, F.J.4    Glass, C.K.5
  • 44
    • 1642415252 scopus 로고    scopus 로고
    • Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis
    • Z. Yuan, Y. Liu, Y. Liu, J. Zhang, C. Kishimoto, and Y. Wang Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis Cardiovasc. Res. 59 2003 685 694
    • (2003) Cardiovasc. Res. , vol.59 , pp. 685-694
    • Yuan, Z.1    Liu, Y.2    Liu, Y.3    Zhang, J.4    Kishimoto, C.5    Wang, Y.6
  • 45
    • 2542458441 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells
    • Z. Yuan, Y. Liu, Y. Liu, J. Zhang, C. Kishimoto, and A. Ma Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells J. Cardiovasc. Pharmacol. 43 2004 868 875
    • (2004) J. Cardiovasc. Pharmacol. , vol.43 , pp. 868-875
    • Yuan, Z.1    Liu, Y.2    Liu, Y.3    Zhang, J.4    Kishimoto, C.5    Ma, A.6
  • 46
    • 0036371311 scopus 로고    scopus 로고
    • Fenofibrate, a peroxisome proliferator-activated receptor alpha activator, suppresses experimental autoimmune myocarditis by stimulating the interleukin-10 pathway in rats
    • S. Maruyama, K. Kato, M. Kodama, S. Hirono, K. Fuse, and O. Nakagawa Fenofibrate, a peroxisome proliferator-activated receptor alpha activator, suppresses experimental autoimmune myocarditis by stimulating the interleukin-10 pathway in rats J. Atheroscler. Thromb. 9 2002 87 92
    • (2002) J. Atheroscler. Thromb. , vol.9 , pp. 87-92
    • Maruyama, S.1    Kato, K.2    Kodama, M.3    Hirono, S.4    Fuse, K.5    Nakagawa, O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.