Molecular engineering of myosin

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 359, Issue 1452, 2004, Pages 1907-1912

  Manstein, Dietmar J ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Actin; Dictyostelium; Myosin; Protein design; X ray structure

Indexed keywords

MUSCLE; PROTEIN;

DICTYOSTELIUM;

EID: 13444261238     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2004.1565     Document Type: Conference Paper

References (57)

1. Anson, M., Geeves, M. A., Kurzawa, S. E. & Manstein, D. J. 1996 Myosin motors with artificial lever arms. EMBO J. 15, 6069-6074.
2. Carragher, B. O., Cheng, N., Wang, Z. Y., Korn, E. D., Reilein, A., Belnap, D. M., Hammer, J. A. & Steven, A. C. 1998 Structural invariance of constitutively active and inactive mutants of Acanthamoeba myosin IC bound to F-actin in the rigor and ADP-bound states. Proc. Natl Acad. Sci. USA 95, 15 206-15 211.
3. Conibear, P. B., Bagshaw, C. R., Fajer, P. G., Kovacs, M. & Malnasi-Csizmadia, A. 2003 Myosin cleft movement and its coupling to actomyosin dissociation. Nat. Struct. Biol. 10, 831-835.
4. Coureux, P. D., Wells, A. L., Menetrey, J., Yengo, C. M., Morris, C. A., Sweeney, H. L. & Houdusse, A. 2003 A structural state of the myosin V motor without bound nucleotide. Nature 425, 419-423.
5. Dominguez, R., Freyzon, Y., Trybus, K. M. & Cohen, C. 1998 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell 94, 559-571.
6. Finer, J. T., Simmons, R. M. & Spudich, J. A. 1994 Single myosin molecule mechanics: piconewton forces and nanometre steps. Nature 368, 113-119.
7. Fisher, A. J., Smith, C. A., Thoden, J. B., Smith, R., Sutoh, K., Holden, H. M. & Rayment, I. 1995 X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry 34, 8960-8972.
8. Funatsu, T., Harada, Y., Tokunaga, M., Saito, K. & Yanagida, T. 1995 Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution. Nature 374, 555-559.
9. Furch, M., Geeves, M. A. & Manstein, D. J. 1998 Modulation of actin affinity and actomyosin adenosine triphosphatase by charge changes in the myosin motor domain. Biochemistry 37, 6317-6326.
10. Furch, M., Remmel, B., Geeves, M. A. & Manstein, D. J. 2000 Stabilization of the actomyosin complex by negative charges on myosin. Biochemistry 39, 11 602-11 608.
11. Geeves, M. A. & Holmes, K. C. 1999 Structural mechanism of muscle contraction. A. Rev. Biochem. 68, 687-728.
12. Goodson, H. V., Warrick, H. M. & Spudich, J. A. 1999 Specialized conservation of surface loops of myosin: evidence that loops are involved in determining functional characteristics. J. Mol. Biol. 287, 173-185.
13. Goody, R. S. & Hofmann-Goody, W. 2002 Exchange factors, effectors, GAPs and motor proteins: common thermodynamic and kinetic principles for different functions. Eur. Biophys. J. 31, 268-274.
14. Gulick, A. M., Bauer, C. B., Thoden, J. B., Pate, E., Yount, R. G. & Rayment, I. 2000 X-ray structures of the Dictyostelium discoideum myosin motor domain with six non-nucleotide analogs. J. Biol. Chem. 275, 398-408.
15. Holmes, K. C. 1997 The swinging lever-arm hypothesis of muscle contraction. Curr. Biol. 7, R112-R118.
16. Holmes, K. C. & Geeves, M. A. 2000 The structural basis of muscle contraction. Phil. Trans. R. Soc. B 355, 419-431. (doi: 10.1098/rstb.2000.0583)
17. Holmes, K. C., Angert, I., Kull, F. J., Jahn, W. & Schröder, R. R. 2003 Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide. Nature 425, 423-427.
18. Houdusse, A. & Sweeney, H. L. 2001 Myosin motors: missing structures and hidden springs. Curr. Opin. Struct. Biol. 11, 182-194.
19. Houdusse, A., Kalabokis, V. N., Himmel, D., Szent-Gyorgyi, A. G. & Cohen, C. 1999 Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell 97, 459-470.
20. Houdusse, A., Szent-Gyorgyi, A. G. & Cohen, C. 2000 Three conformational states of scallop myosin S1. Proc. Natl Acad. Sci. USA 97, 11 238-11 243.
21. Huxley, A. F. 1957 Muscle structure and theories of contraction. Prog. Biophys. Biophys. Chem. 7, 255-318.
22. Huxley, A. F. & Niedergerke, R. 1954 Structural changes in muscle during contraction; interference microscopy of living muscle fibres. Nature 173, 971-973.
23. Huxley, A. F. & Hanson, J. 1954 Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature 173, 973-976.
24. Huxley, H. E. 1957 The double array of filaments in cross-striated muscle. J. Biophys. Biochem. Cytol. 3, 631-648.
25. Huxley, H. E. 1969 The mechanism of muscular contraction. Science 164, 1356-1365.
26. Huxley, H. & Hanson, J. 1954 Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature 173, 973-976.
27. Ishijima, A., Kojima, H., Funatsu, T., Tokunaga, M., Higuchi, H., Tanaka, H. & Yanagida, T. 1998 Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin. Cell 92, 161-171.
28. Ito, K., Kashiyama, T., Shimada, K., Yamaguchi, A., Awata, J., Hachikubo, Y., Manstein, D. J. & Yamamoto, K. 2003 Recombinant motor domain constructs of Chara corallina myosin display fast motility and high ATPase activity. Biochem. Biophys. Res. Commun. 312, 958-964.
29. Kliche, W., Fujita-Becker, S., Kollmar, M., Manstein, D. J. & Kull, F. J. 2001 Structure of a genetically engineered molecular motor. EMBO J. 20, 40-46.
30. Kollmar, M., Dürrwang, U., Kliche, W., Manstein, D. J. & Kull, F. J. 2002 Crystal structure of the motor domain of a class-I myosin. EMBO J. 21, 2517-2525.
31. Kron, S. J. & Spudich, J. A. 1986 Fluorescent actin filaments move on myosin fixed to a glass surface. Proc. Natl Acad. Sci. USA 83, 6272-6276.
32. Kurzawa, S. E., Manstein, D. J. & Geeves, M. A. 1997 Dictyostelium discoideum myosin II: characterization of functional myosin motor fragments. Biochemistry 36, 317-323.
33. Kurzawa-Goertz, S. E., Perreault-Micale, C. L., Trybus, K. M., Szent-Gyorgyi, A. G. & Geeves, M. A. 1998 Loop I can modulate ADP affinity, ATPase activity, and motility of different scallop myosins. Transient kinetic analysis of S1 isoforms. Biochemistry 37, 7517-7525.
34. Levitsky, D. I., Ponomarev, M. A., Geeves, M. A., Shnyrov, V. L. & Manstein, D. J. 1998 Differential scanning calorimetric study of the thermal unfolding of the motor domain fragments of Dictyostelium discoideum myosin II. European J. Biochem. 251, 275-280.
35. Lymn, R. W. & Taylor, E. W. 1971 Mechanism of adenosine triphosphate hydrolysis by actomyosin. Biochemistry , 4617-4624.
36. Manstein, D. J., Ruppel, K. M. & Spudich, J. A. 1989 Expression and characterization of a functional myosin head fragment in Dictyostelium discoideum. Science 246, 656-658.
37. Matsu-ura, M. & Ikebe, M. 1995 Requirement of the two-headed structure for the phosphorylation dependent regulation of smooth muscle myosin. FEBS Lett. 363, 246-250.
38. Molley, J. E., Burns, J. E., Kendrick-Jones, J., Tregear, R. T. & White, D. C. 1995a Movement and force produced by a single myosin head. Nature 378, 209-212.
39. Molley, J. E., Sparrow, J. C., Tregear, R. T., Kendrick-Jones, J. White, D. C. 1995b Single-molecule mechanics of heavy meromyosin and S1 interacting with rabbit or Drosophila actins using optical tweezers. Biophys. J. 68(Suppl.), 298S-303S.
40. Murphy, C. T. & Spudich, J. A. 2000 Variable surface loops and myosin activity: accessories to a motor. J. Muscle Res. Cell Motil. 21, 139-151.
41. Ponomarev, M. A., Furch, M., Levitsky, D. I. & Manstein, D. J. 2000 Charge changes in loop 2 affect the thermal unfolding of the myosin motor domain bound to F-actin. Biochemistry 39, 4527-4532.
42. Prakash, B., Renault, L., Praefcke, G. J., Herrmann, C. & Wittinghofer, A. 2000 Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO J. 19, 4555-4564.
43. Rayment, I., Holden, H. M., Whittaker, M., Yohn, C. B., Lorenz, M., Holmes, K. C. & Milligan, R. A. 1993 Structure of the actin-myosin complex and its implications for muscle contraction. Science 261, 58-65.
44. Reedy, M. K., Holmes, K. C. & Tregear, R. T. 1965 Induced changes in orientation of the cross-bridges of glycerinated insect flight muscle. Nature 207, 1276-1280.
45. Reubold, T. F., Eschenburg, S., Becker, A., Kull, F. J. & Manstein, D. J. 2003 A structural model for actin-induced nucleotide release in myosin. Nature Struct. Biol. 10, 826-830.
46. Ruff, C., Furch, M., Brenner, B., Manstein, D. J. & Meyhofer, E. 2001 Single-molecule tracking of myosins with genetically engineered amplifier domains. Nature Struct. Biol. 8, 226-229.
47. Schröder, R. R., Manstein, D. J., Jahn, W., Holden, H., Rayment, I., Holmes, K. C. & Spudich, J. A. 1993 Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature 364, 171-174.
48. Sheetz, M. P. & Spudich, J. A. 1983 Movement of myosin-coated structures on actin cables. Cell Motil. 3, 485-489.
49. Sweeney, H. L., Rosenfeld, S. S., Brown, F., Faust, L., Smith, J., Xing, J., Stein, L. A. & Sellers, J. R. 1998 Kinetic tuning of myosin via a flexible loop adjacent to the nucleotide binding pocket. J. Biol. Chem. 273, 6262-6270.
50. Trybus, K. M. 1994 Regulation of expressed truncated smooth muscle myosins. Role of the essential light chain and tail length. J. Biol. Chem. 269, 20 819-20 822.
51. Tsiavaliaris, G., Fujita-Becker, S. & Manstein, D. J. 2004 Molecular engineering of a backwards-moving myosin motor. Nature 427, 558-561.
52. Uyeda, T. Q., Ruppel, K. M. & Spudich, J. A. 1994 Enzymatic activities correlate with chimaeric substitutions at the actin-binding face of myosin. Nature 368, 567-569.
53. Vale, R. D. 1996 Switches, latches, and amplifiers: common themes of G proteins and molecular motors. J. Cell Biol. 135, 291-302.
54. Van Dijk, J., Furch, M., Lafont, C., Manstein, D. J. & Chaussepied, P. 1999 Functional characterization of the secondary actin binding site of myosin II. Biochemistry 38, 15078-15085.
55. Volkmann, N., Hanein, D., Ouyang, G., Trybus, K. M., DeRosier, D. J. & Lowey, S. 2000 Evidence for cleft closure in actomyosin upon ADP release. Nature Struct. Biol. 7, 1147-1155.
56. Wells, A. L., Lin, A. W., Chen, L. Q., Safer, D., Cain, S. M., Hasson, T., Carragher, B. O., Milligan, R. A. & Sweeney, H. L. 1999 Myosin VI is an actin-based motor that moves backwards. Nature 401, 505-508.
57. Yanagida, T., Nakase, M., Nishiyama, K. & Oosawa, F. 1984 Direct observation of motion of single F-actin filaments in the presence of myosin. Nature 307, 58-60.