The swinging lever-arm hypothesis of muscle contraction

Current Biology

Volumn 7, Issue 2, 1997, Pages

  Holmes, Kenneth C ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; DICTYOSTELIUM;

EID: 0031079847     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00051-0     Document Type: Review

References (27)

1. Huxley HE: The mechanism of muscular contraction. Science 1969, 164:1356-1366.
2. Lymn RW, Taylor EW: Mechanism of adenosine triphosphate hydrolysis of actomyosin. Biochemistry 1971, 10:4617-4624.
3. Huxley AF, Simmons R: Proposed mechanism of force generation in striated muscle. Nature 1971, 233:533-538.
4. Cooke R: The mechanism of muscle contraction. CRC Crit Rev. Biochem 1986, 21:53-118.
5. Kabsch W, Mannherz HG, Suck D, Pai EF, Holmes KC: Atomic structure of the actin:DNase I complex. Nature 1990, 347:37-44.
6. Holmes KC, Popp D, Gebhard W, Kabsch W: Atomic model of the actin filament. Nature 1990, 347:44-49.
7. Lorenz M, Popp D, Holmes K : Reinement of the F-actin model against X-ray fiber diffraction data by the use of a directed mutation algorithm. J Mol Biol 1993, 234:826-836.
8. Rayment I, Rypniewski WR, Schmidt-Base K, Smith R, Tomchick DR, Benning MM, Winkelmann DA, Wesenberg G, Holden HM: Three-dimensional structure of myosin subfragment-1: a molecular motor. Science 1993, 261:50-58.
9. Rayment I, Holden HM, Whittaker M, Yohn CB, Lorenz M, Holmes KC, Milligan RA: Structure of the actin-myosin complex and its implications for muscle contraction. Science 1993, 261:58-65.
10. -. Biochemistry 1995, 34:8960-8972.
11. Smith CA, Rayment I: X-ray structure of the magnesium(ii).ADP.vanadate complex of the Dictyostelium-discoideum myosin motor domain to 1.9 resolution. Biochemistry 1996, 35:5404-5417.
12. Cope M, Whisstock J, Rayment I, Kendrick-Jones J: Conservation within the myosin motor domain - implications for structure and function. Structure 1996, 4:969-987.
13. Mornet D, Pantel P, Audemard E, Kassab R: The limited tryptic cleavage of chymotriptic S1: an approach to the characterisation of the actin site in myosin heads. Biochem Biophys Res Comm 1979, 89:925-932.
14. Houdusse A, Cohen C: Structure of the regulatory domain of scallop myosin at 2Å resolution: implications for regulation. Structure 1996, 4:21-32.
15. Schroeder RR, Manstein DJ, Jahn W, Holden H, Rayment I, Holmes KC, Spudich JA: Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature 1993, 364:171-174.
16. Milligan RA, Flicker PF: Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J Cell Biol 1987, 105:29-39.
17. Jontes JD, Wilson-Kubalek EM, Milligan RA: The brush border myosin-1 tail swings through a 32° arc upon ADP release. Nature 1995, 378:751-753.
18. Whittaker M, Wilson-Kubalek EM, Smith JE, Faust L, Milligan RA, Sweeney HL: Smooth muscle myosin moves 35Å upon ADP release. Nature 1995, 378:748-751.
19. Uyeda T, Abramson PD, Spudich JA: The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc Natl Acad Sci USA 1996, 93:4459-4464.
20. Anson M, Geeves MA, Kurzawa SE, Manstein D: Myosin motors with artificial lever arms. EMBO J 1996, 15:6069-6074.
21. Patterson B, Spudich JA: Cold-sensitive mutations of Dictyostelium myosin heavy-chain highlight functional domains of the myosin motor. Genetics 1996, 143:801-810.
22. Kinose F, Wang SX, Kidambi US, Moncman CL, Winkelmann DA: Glycine 699 is pivotal for the motor activity of skeletal muscle myosin. J Cell Biol 1996, 134:895-909.
23. Irving M, Allen TS, Sabidodavid C, Craik JS, Brandmeier B, Kendrick-Jones J, Corrie JET, Trentham DR, Goldman YE: Tilting of the light-chain region of myosin during step length changes and active force generation in skeletal muscle. Nature 1995, 375:688-691.
24. Huston EE, Grammer JC, Yount RG : Flexibility of the myosin heavy chain: direct evidence that the region containing SH1 and SH2 can move 10 Å under the influence of nucleotide binding. Biochemistry 1988, 27:8945-8952.
25. Kursawa SE, Manstein DJ, Geeves MA: Dictyostelium discoidium myosin II: characterisation of functional myosin motor fragments. Biochemistry 1997, in press:
26. Smith CA, Rayment I: Active site comparisons highlight structural similarities between myosin and other P-loop proteins. Biophys J 1996, 70:1590-1602.
27. Nicholls A, Sharp KA, Honig B: Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 1991, 11:281-296.