A molecular analysis of prion protein expression in Alzheimer's disease

McGill Journal of Medicine

Volumn 8, Issue 1, 2004, Pages 7-14

  McNeill, Alisdair ^a,b  

^a Western Infirmary Glasgow ^*  (United Kingdom)

^b GARTNAVEL GENERAL HOSPITAL   (United Kingdom)

Author keywords

Alzheimer's; Immunohistochemistry; Prion protein; Western Blotting

Indexed keywords

PRION PROTEIN; SUPEROXIDE DISMUTASE;

ADULT; AGED; ALZHEIMER DISEASE; AMYLOIDOSIS; ARTICLE; BRAIN TUMOR; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; FEMALE; GENOTYPE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; ISOMERIZATION; MALE; MOLECULAR BIOLOGY; NERVE CELL; NEUROPATHOLOGY; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FOLDING; QUANTITATIVE ANALYSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; WESTERN BLOTTING;

EID: 13444249545     PISSN: 1201026X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Ironside JW. Prion Diseases In Man. Journal of Pathology 186(3):227-234; 1998.
2. Collinge J, Whittington MA, Sidle KC, et al. Prion Protein Is Necessary For Normal Synaptic Function. Nature 370(6487):295-297; 1994.
3. Herms J, Tings T, Gall S, et al. Evidence Of Presynaptic Location And Function Of The Prion Protein. Journal of Neuroscience 19(20):8866-8875; 1999.
4. Moore RC, Lee IY, Silverman GL, et al. Ataxia In Prion Protein Deficient Mice Is Associated With Upregulation Of The Novel PrP - Like Protein Doppel. Journal of Molecular Biology 292(4):797-817; 1999.
5. Brown DR, Besinger A. Prion Protein And Superoxide Dismutase Activity. Biochemical Journal 334:423-429; 1998.
6. Brown DR, Schulz-Schaeffer WJ, Schmidt B, Kretzschmar HA. Prion Protein Deficient Cells Show Altered Response To Oxidative Stress Due To Decreased SOD -1 Activity. Experimental Neurology 146(1):104-112; 1997.
7. Voigtlander T, Kloppel S, Birner P, et al. Marked Increase Of Neuronal Prion Protein Immunoreactivity In Alzheimer's Disease And Human Prion Diseases. Acta Neuropathologica 101(5):417-423; 2001.
8. Ferrer I, Blanco R, Carmona M, et al. Prion Protein Expression In Senile Plaques In Alzheimer's Disease. Acta Neuropathologica 101(1):49-56; 2001.
9. Perry RT, Go RCP, Harrell LE, et al. SSCP Analysis And Sequencing Of The Prion Protein Gene Detects Two 24 bp Deletions In An Atypical Alzheimer's Disease Family. American Journal of Medical Genetics 60(1):12-18; 1995.
10. Casadei VM, Ferri C, Calabrese E, et al. Prion Protein Gene Polymorphism And Alzheimer's Disease: One Modulatory Trait of Cognitive Decline? Journal of Neurology, Neurosurgery and Psychiatry 71(2):279-280; 2001
11. Leuba G, Saini K, Savioz A, Charnay Y. Early Onset Familial Alzheimer Disease With Co-existing -Amyloid And Prion Pathology. Journal of the American Medical Association 283(13):756; 2000.
12. Graham DI, Lantos PL. Ageing And Dementia. In: Graham DI, Lantos PL, eds. Greenfield's Neuropathology. London: Arnold, 1997.
13. Lyras L, Cairns NJ, Jenner A, Jenner P, Halliwell B. An Assessment Of Oxidative Damage To Proteins, Lipids, And DNA In Brain From Patients With Alzheimer's Disease. Journal of Neurochemistry 68(5):2061-2069; 1997.
14. Yatin SM, Aksenova M, Aksenov M, et al. Temporal relations among amyloid beta-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses. Journal of Molecular Neuroscience 11(3):183-97; 1998.
15. Celsi F, Ferri A, Casciati A, et al. Overexpression of SOD-1 Protects Against -Amyloid Peptide Toxicity: Effect of Oestrogen and Copper Chelators. Neurochemistry International 44(1):25-33; 2004.
16. McLennan NF, Rennison KA, Bell JE, Ironside JW. In Situ Hybridisation Analysis Of PrP mRNA In Human CNS Tissue. Neuropath. Applied Neurobiology 27(5):373-383; 2001.
17. DeArmond SJ. Alzheimer's Disease and Creutzfeldt-Jakob Disease: Overlap Of Pathogenic Mechanisms. Currents Opinions in Neurology 6(6):872-881; 1993.
18. Hainfellner JA, Wanschitz J, Jellinger K, Liberski PP, Gullotta F, Budka H. Coexistance Of Alzheimer-Type Neuropathology In Creutzfeldt Jakob Disease. Acta Neuropathologica 96(2):116-122; 1998.
19. Forloni G, Tagliavini F, Bugiani O, Salmona M. Amyloid in Alzheimer's Disease And Prion Related Encephalopathies: Studies With Synthetic Peptides. Progress in Neurobiology 49(4):287-315; 1996.
20. Dickson DW. The Pathogenesis of Senile Plaques. Journal of Neuropathology and Experimental Neurology 56(4):321-339; 1997.
21. Kovacs GG, Zerbi P, Voigtlander T, et al. The Prion Protein In Human Neurodegenerative Disorders. Neuroscience Letters 329(3):269-272; 2002.