Minimal mutations are required to effect a radical change in function in CEA family members of the lg superfamily

Journal of Cell Science

Volumn 117, Issue 5, 2004, Pages 761-769

  Naghibalhossaini, Fakhraddin ^a,b   Stanners, Clifford ^a  

^a MCGILL UNIVERSITY   (Canada)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

CEA; CEACAMI; Evolution; GPI; Ig superfamily

Indexed keywords

CARCINOEMBRYONIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; GLYCOSYLPHOSPHATIDYLINOSITOL; MUTANT PROTEIN; PHOSPHOLIPASE C;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL ANCHORAGE; CELL DIFFERENTIATION; CELL MEMBRANE; CONTROLLED STUDY; EXON; FLUORESCENCE ACTIVATED CELL SORTING; GENE DELETION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STOP CODON;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; BASE SEQUENCE; CARCINOEMBRYONIC ANTIGEN; CELL ADHESION; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL LINE; CRICETINAE; CRICETULUS; FLOW CYTOMETRY; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; IMMUNOGLOBULINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; SEQUENCE ANALYSIS;

ANIMALIA; PRIMATES;

EID: 1342347557     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00903     Document Type: Article

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