Identification of a novel isoform of ZAP-70, truncated ZAP kinase

Biochemical and Biophysical Research Communications

Volumn 315, Issue 4, 2004, Pages 935-941

  Kuroyama, Hiroyuki ^a   Ikeda, Tohru ^a   Kasai, Michiyuki ^b   Yamasaki, Sho ^c   Tatsumi, Masashi ^b   Utsuyama, Masanori ^a   Saito, Takashi ^c,d   Hirokawa, Katsuiku ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d RIKEN   (Japan)

Author keywords

Immune synapse; Microtubule organizing center; T lymphocyte; T cell receptor; Tyrosine kinase; ZAP 70

Indexed keywords

ISOENZYME; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME MODIFICATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SYNAPSE; T LYMPHOCYTE; THYMOCYTE; TISSUE DISTRIBUTION;

EID: 1342345243     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.01.127     Document Type: Article

References (29)

1. Chan A.C., Iwashima M., Turck C.W., Weiss A. ZAP-70: a 70. kd protein-tyrosine kinase that associates with the TCR ζ chain Cell. 71:1992;649-662.
2. Weiss A., Littman D.R. Signal transduction by lymphocyte antigen receptors. Cell. 76:1994;263-274.
3. Iwashima M., Irving B.A., van Oers N.S.C., Chan A.C., Weiss A. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science. 263:1994;1136-1139.
4. van Oers N.S.C., Killeen N., Weiss A. Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. J. Exp. Med. 183:1996;1053-1062.
5. Hatada M.H., Xiaode L., Laird E.R., Green J., Morgenstein J.P., Lou M., Marr C.S., Phillips T.B., Ram M.K., Theriault K., Zoller M.J., Karas J.L. Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor. Nature. 377:1995;32-38.
6. Visco C., Magistrelli G., Bosotti R., Perego R., Rusconi L., Toma S., Zamai M., Acuto O., Isacchi A. Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding. Biochemistry. 39:2000;2784-2791.
7. Negishi I., Motoyama N., Nakayama K., Nakayama K., Senju S., Hatakeyama S., Zhang Q., Chan A.C., Loh D.Y. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature. 376:1995;435-438.
8. Cheng A.M., Negishi I., Anderson S.J., Chan A.C., Bolen J., Loh D.Y., Pawson T. The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc. Natl. Acad. Sci USA. 94:1997;9797-9801.
9. Elder M.E. Severe combined immunodeficiency due to a defect in the tyrosine kinase ZAP-70. Pediatr. Res. 39:1996;743-748.
10. Elder M.E. SCID due to ZAP-70 deficiency. J. Pediatr. Hematol. Oncol. 19:1997;546-550.
11. Elder M.E., Lin D., Clever J., Chan A.C., Hope T.J., Weiss A., Parslow T.G. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science. 264:1994;1596-1599.
12. Chan A.C., Kadlecek T.A., Elder M.E., Filipovich A.H., Kuo W.L., Iwashima M., Parslow T.G., Weiss A. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science. 264:1994;1599-1601.
13. + thymic selection in humans lacking Zap-70 kinase. Cell. 76:1994;947-958.
14. Gelfand E.W., Weinberg K., Mazer B.D., Kadlecek T.A., Weiss A. Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. J. Exp. Med. 182:1995;1057-1065.
15. Blanchard N., Bartolo V.D., Hivroz C. In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern. Immunity. 17:2002;389-399.
16. Ikeda T., Kasai M., Utsuyama M., Hirokawa K. Determination of three isoforms of the receptor activator of nuclear factor-. κ B ligand and their differential expression in bone and thymus Endocrinology. 142:2001;1419-1426.
17. Kasai M., Kominami E., Mizuochi T. The antigen presentation pathway in medullary thymic epithelial cells, but not that in cortical thymic epithelial cells, conforms to the endocytic pathway. Eur. J. Immunol. 28:1998;1867-1876.
18. Hachiya A., Aizawa S., Tanaka M., Takahashi Y., Ida S., Gatanaga H., Hirabayashi Y., Kojima A., Tatsumi M., Oka S. Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing Hela/CD4(+) cell clone 1-10 (MAGIC-5). Antimicrob. Agents Chemother. 45:2001;495-501.
19. Williams B.L., Schreiber K.L., Zhang W., Wange R.L., Samelson L.E., Leibson P.J., Abraham R.T. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Mol. Cell. Biol. 18:1998;1388-1399.
20. Yamasaki S., Nishida K., Hibi M., Sakuma M., Shiina R., Takeuchi A., Ohnishi H., Hirano T., Saito T. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules. J. Biol. Chem. 276:2001;45175-45183.
21. Booth J.W., Kim M.K., Jankowski A., Schreiber A.D., Grinstein S. Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis. EMBO J. 21:2002;251-258.
22. Ishijima S.-A., Zeng Y.-X., Kurashima C., Utsuyama M., Shirasawa T., Sakamoto K., Hirokawa K. Expression of ZAP-70 gene in the developing thymus and various nonlymphoid tissues of embryonic and adult mice. Cell. Immunol. 165:1995;278-283.
23. Chu D.H., van Oers N.S.C., Malissen M., Harris J., Elder M., Weiss A. Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression. J. Immunol. 163:1999;2610-2620.
24. Grakoui A., Bromley S.K., Sumen C., Davis M.M., Shaw A.S., Allen P.M., Dustin M.L. The immunological synapse: a molecular machine controlling T cell activation. Science. 285:1999;221-227.
25. Dustin M.L., Cooper J.A. The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nat. Immunol. 1:2000;23-28.
26. Monks C.R., Freiberg B.A., Kupfer H., Sciaky N., Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature. 395:1998;82-86.
27. Kupfer A., Dennert G. Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells. J. Immunol. 133:1984;2762-2766.
28. Kupfer A., Mosmann T.R., Kupfer H. Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells. Proc. Natl. Acad. Sci. USA. 88:1991;775-779.
29. Lowin-Kropf B., Shapiro V.S., Weiss A. Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism. J. Cell Biol. 140:1998;861-871.